Original ResearchPublished 16 January 2026Enhancing structure-based virtual screening of MDM2–p53 inhibitors: a benchmark of machine learning vs. traditional docking scoring functionsMarcia Yineth Castillo Tarazona · Gian Pietro MiscioneFrontiers in Drug Discoverydoi 10.3389/fddsv.2025.1731262
Brief Research ReportPublished 5 January 2026Dual RNA polymerase I inhibition with CX-5461 and BMH-21 synergizes in breast cancer by activating p53-dependent stressJonathan Y. Chung · Kristen N. Nguyen · Bruce A. KnutsonFrontiers in Drug Discoverydoi 10.3389/fddsv.2025.1677461
