Review
Published
Artificial intelligence for full-cycle clinical management in orthokeratology: a comprehensive review
Xiaotong Wang · Haojiang Yang
Frontiers in Medicine
doi 10.3389/fmed.2026.1950432
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Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 50 articles
Review
Published
Gut microbiota, microbial metabolites, and mucosal barrier dysfunction in benign anorectal disorders and ulcerative colitis: shared mechanisms, clinical links, and precision interventions
Hexue Yuan · Maofang Zhao · Yunfen Wang · Chen Shen · Delong Liu · Chunxiao Wang · Jian Liu
Frontiers in Medicine
doi 10.3389/fmed.2026.1979206
Editorial
Published
Editorial: Advances in early detection, pathophysiology, and management of mild cognitive impairment
Edgar Vásquez-Carrasco · Cristian Sandoval-Vásquez · Pablo Valdés-Badilla
Frontiers in Medicine
doi 10.3389/fmed.2026.2007251
Case Report
Published
Case Report: Delayed non-calculous biliary obstruction after left hepatectomy associated with intraductal necrotic material with a biliary epithelial component
Ye Wang · Shengchen Nan · Xu Jiang · Xinglin Jin
Frontiers in Medicine
doi 10.3389/fmed.2026.1967233
Perspective
Published
Bridging global standards and local needs: a realist perspective on glocalisation in medical education
Ronan Daly · Muirne Spooner
Frontiers in Medicine
doi 10.3389/fmed.2026.1967360
Correction
Published
Correction: Impact of structured mentorship on professional identity and career development among medical residents: a cross-sectional study in China
Jiayi Tan · Li Jiang · Bo Huang
Frontiers in Medicine
doi 10.3389/fmed.2026.1999534
Systematic Review
Published
The dementia fear among older adults: a scoping review
Lin Wang · Guihua Xiong · Xue Dong
Frontiers in Medicine
doi 10.3389/fmed.2026.1938388
Original Research
Published
Age as a significant prognostic factor in patients meeting the global ARDS definition but not the Berlin definition
Pan Pan · Jin Chen · Tiantian Zhang · Cheng Haibo · Zhang Wanyi · Xiaobo Han · Han Xinjie · Hu Xingshuo · Yang Qingyun · Gu Hongjun · Liu Yuhong · Lixin Xie
Frontiers in Medicine
doi 10.3389/fmed.2026.1929746
Original Research
Published
A comparison of clinical phenotype and outcomes in anti- melanoma differentiation-associated protein 5 dermatomyositis and anti-synthetase syndrome in a multiethnic cohort in Singapore
Choon-Guan Chua · Zhaoxiang Fan · Hwee-Pin Phua · Wei-Yen Lim · Gin Tsen Chai · Mona Manghani
Frontiers in Medicine
doi 10.3389/fmed.2026.1969582
Original Research
Published
Effects of isobaric spinal anesthesia combined with different nerve block techniques on postoperative pain and complications in elderly patients undergoing proximal femoral nail antirotation: a retrospective observational study
Jingjing Li · Ning Ma · Yuan Zhao · Na Liang · Yanbin Zhao
Frontiers in Medicine
doi 10.3389/fmed.2026.1813736
Original Research
Published
Risk factors for invasive fungal infections after kidney transplantation and the construction of a predictive model
Lulu Tang · Jiqiu Wen · Hongdi Xiong · Chunying Lv · Jianhui Dong · Ning Wen · Guomei Huang · Zhiwen Jiang · Haiju Chen · Cairong Yan · Shuangshuang Li · Yuyang Jiang · Yi Wu · Cunwei Cao · Xuyong Sun
Frontiers in Medicine
doi 10.3389/fmed.2026.1850921
Mini Review
Published
Predicting spinal hypotension during cesarean delivery: what is being predicted, and when
Yi Zhang · Shuang Guo · Qingjun Zeng · Chaowen Fu
Frontiers in Medicine
doi 10.3389/fmed.2026.1989191
Review
Published
Non-acid reflux and reflux laryngitis: new perspectives on mechanism, diagnosis and treatment
Hongshan Chang · Rui Sun · Huan Qiu · Yunhong Ning · Lei Yao
Frontiers in Medicine
doi 10.3389/fmed.2026.1949945
Review
Published
Periocular rejuvenation: current concepts and evidence-based management
Alessio Martucci · Flavia Quaranta Leoni · Matteo Di Marino · Enrico Romano
Frontiers in Medicine
doi 10.3389/fmed.2026.1943441
Case Report
Published
Primary pulmonary mucoepidermoid carcinoma: a case report
Shaoyong Dong · Jing Sun · Ying Yang
Frontiers in Medicine
doi 10.3389/fmed.2026.1893850
Original Research
Published
Current status of medical students’ use of large language models for graduation thesis writing: a comparative cross-sectional survey
Xuexiu Liu · Junyang Luo · Yanhan Chen · Jianjun Zhu · Yi Liu · Zhengjie Wang
Frontiers in Medicine
doi 10.3389/fmed.2026.1948768
Case Report
Published
Case Report: Isolated leptomeningeal relapse after systemic control in PALB2-altered pancreatic cancer
Jian Yuan · Yangxian Xu · Qihao Zhou · Guorong Yuan · Meizhen Ye
Frontiers in Medicine
doi 10.3389/fmed.2026.1927688
Original Research
Published
Incremental prognostic value of the T-helper 1/T-helper 2 immune phenotype and 72-h change in sequential organ failure assessment for in-hospital mortality in sepsis with and without type 2 diabetes: a retrospective two-cohort study
Dongxu Pan · Zongnan Lv · Jiayan Li · Bo Zhang · Feifei Xu · Wuxiang Huang · Wei Chen · Xuejun Mo
Frontiers in Medicine
doi 10.3389/fmed.2026.1911557
Review
Published
Surgery-related factors predisposing to uterine niche after cesarean section: a systematic review
Natalia Katarzyna Mazur-Ejankowska · Anna Abacjew-Chmylko · Maciej Ejankowski · Dariusz Grzegorz Wydra · Magdalena Emilia Grzybowska
Frontiers in Medicine
doi 10.3389/fmed.2026.1838075
Original Research
Published
High performance white blood cell classification using ensemble CNNs with Monte Carlo dropout and conformal prediction for clinical uncertainty quantification
Shahid Mehmood · Abeer A. K. Alharbi · Mona Alkhattabi · Muhammad Adnan Khan · Muhammad Amir Khan
Frontiers in Medicine
doi 10.3389/fmed.2026.1959061
Original Research
Published
Multi-sequence magnetic resonance imaging radiomics integrated with clinical features predicts pelvic lymph node metastasis in cervical cancer: a retrospective-prospective cohort study
Wanqing Gong · Xiaoyi Liu · Mengli Wang · Xiaowen Hu · Guangping Yan · Kun Liu · Yongxin Li · Tingting Zhang
Frontiers in Medicine
doi 10.3389/fmed.2026.1910248
Case Report
Published
Concurrent Bartholin gland and perianal abscesses in a woman: a case report of a diagnostic challenge
Jiansheng Hu · Liyun Dong · Linmei Sun · Hongbo Su
Frontiers in Medicine
doi 10.3389/fmed.2026.1982913
Systematic Review
Published
Interdisciplinary care models for functional movement disorders: a systematic review of clinical effectiveness and implications for integrated healthcare delivery
Anabel Granja-Dominguez · Juan Máximo Molina-Linde · Patricia García-Sanz · María Piedad Rosario-Lozano · Juan Antonio Blasco-Amaro · Alberto Marcos Heredia-Rizo
Frontiers in Medicine
doi 10.3389/fmed.2026.1939816
Case Report
Published
Case Report: Bacteremic respiratory tularemia causing refractory ARDS requiring VV-ECMO
Cynthia Wenglinski · Fabrizio Buttafuoco · Michaël Piagnerelli
Frontiers in Medicine
doi 10.3389/fmed.2026.1965100
Mini Review
Published
Hidden labor, monitoring, and exit burdens after hospital operational AI deployment: implications for resource-constrained Chinese hospitals
Xieyi Wang · Hezhuo Wang
Frontiers in Medicine
doi 10.3389/fmed.2026.1985884
Case Report
Published
Osteopathic manipulative treatment as an adjunct therapy in a pediatric patient with chronic pancreatitis and visceral hyperalgesia: a case report
Avrohom Levy · Haili Bach · Fernando Medina Carbonell · Aniruddh Setya
Frontiers in Medicine
doi 10.3389/fmed.2026.1839129
Case Report
Published
Glioblastoma, IDH-wildtype, with spontaneous transdural and calvarial invasion: a case report and literature review
Jianhang Lin · Jiayi Lin · Jiana Zhang · Haiqing Xie · Dawei Liu · Shaolei Guo
Frontiers in Medicine
doi 10.3389/fmed.2026.1908149
Original Research
Published
Healthcare professionals’ knowledge, attitudes, and practices regarding perioperative ischemic stroke in elderly patients
Li Zhang · Hao Nie · Hui Sun · Jianwei Li · Yunpeng Hei · Maoxian Zhang
Frontiers in Medicine
doi 10.3389/fmed.2026.1745538
Original Research
Published
Radiomics-based interpretable machine learning model for identifying high-risk patients with small bowel obstruction: a multicenter study
Guozheng Zhang · Xiaohui Liu · Weitao Huang · Xisong Zhu · Cong Xia · Hua Xia · Yuguo Wei · Xiaowei Han · Danqiong Wang
Frontiers in Medicine
doi 10.3389/fmed.2026.1848334
Case Report
Published
Case Report: Late-onset BK polyomavirus-associated nephropathy with encephalitis, antibody-mediated rejection, and atypical hemolytic uremic syndrome: a rare overlap causing allograft dysfunction, therapeutic challenges, and multidisciplinary management
Jie Zhou · Lichuan Yang · Jiaojiao Zhou
Frontiers in Medicine
doi 10.3389/fmed.2026.1981467
Case Report
Published
Case Report: Beyond the stomach: the role of preoperative imaging in assessing regurgitation risk in patients with esophageal dilatation: a report of two cases
Kecheng Huang · Rongpeng Pi · Jieyu Fang
Frontiers in Medicine
doi 10.3389/fmed.2026.1933635
Original Research
Published
Low arterial oxygen-content burden during the first 24 h and hospital mortality in mechanically ventilated adults: analyses of MIMIC-IV and eICU
Xiaoyan Gao · Jiaqi Wang · Luyan Xiong · Bingzhu Hu · Cheng Jiang · Juan Li · Shi Chen · Cong Zhang
Frontiers in Medicine
doi 10.3389/fmed.2026.1935082
Case Report
Published
Amelanotic subungual melanoma becoming clinically apparent within 24 h after minor blunt trauma: a case report
Huiru Wang · Peng Wang · Yanyan Suo · Kang Lu · Qingfeng Xue · Huahua Li · Rui Gao · Yunchang Guo · Songjia Qu · Xiaowei Cai
Frontiers in Medicine
doi 10.3389/fmed.2026.1991898
Original Research
Published
Development and temporal validation of a calibrated machine learning model for in-hospital blood culture positivity using routine clinical data
Tao Huang · Zhenzhen Tan · Longyang Jiang · Xuping Yang · Shurong Wang · Yilan Huang
Frontiers in Medicine
doi 10.3389/fmed.2026.1956921
Systematic Review
Published
Modified frailty index versus risk analysis index for 30-day mortality after noncardiac surgery: a systematic review and meta-analysis
Xinrui Yin · Shijia Du
Frontiers in Medicine
doi 10.3389/fmed.2026.1885620
Case Report
Published
Expect the unexpected: cervical gastric-type adenocarcinoma in situ in a patient with long-standing Peutz-Jeghers syndrome — a case report and literature review
Shuo Xu · Xinjun Li · Xiangnan Zhang · Shengpu Wang
Frontiers in Medicine
doi 10.3389/fmed.2026.1944455
Original Research
Published
A multi-class fundus disease classification framework based on self-supervised contrastive learning and dual-branch network
Lili Cai · Keke Hou · Zhong Mo · Shining Ding
Frontiers in Medicine
doi 10.3389/fmed.2026.1932626
Case Report
Published
Extensive vulvar and perianal langerhans cell histiocytosis with clinical improvement during low-dose thalidomide and topical therapy: a case report
Pan Zou · Xiao Mei Zhu
Frontiers in Medicine
doi 10.3389/fmed.2026.1969330
Study Protocol
Published
Clinical profiles, referral patterns and low vision aid prescribing across four rehabilitation centres in Ghana: protocol for a multicentre retrospective record review
Kwadwo Owusu Akuffo · Josephine Ampong · Josephine Ampomah Boateng · Caleb Ofosu Yeboah · Lovinger Ato Quansah · Richard Atakora Baafi · Edward Aboagye Yeboah · Isaiah Osei Duah Junior · Sylvia Agyekum · Sylvester Kyeremeh · David Ben Kumah · Albert Kwadjo Amoah Andoh · Emmanuel Tettey Doku · Gabriel Kwaku Agbeshie · Samuel Oteng Brako · Kenneth Bempah Karikari · Nana Akwasi Owusu Mensah · Eldrick Adu Acquah · Ellis Sarpong Mainuh · Maame Abena Kesewah Boaitey · Bright Owusu Prempeh · Louis Oteng-Gyimah · Afua Asantewaa Nkansah · Patience Boatemaa-Twum · Henry Owusu Bota · Josephine Boakye Owusu · Golda Dokuaa Kwapong · Nicholas Sarpong · Hornametor Yao Afake · Werner Eisenbarth
Frontiers in Medicine
doi 10.3389/fmed.2026.1936778
Original Research
Published
Undergraduate nursing students' clinical adaptation: a qualitative journey mapping study from student and clinical preceptor perspectives
Chuanqin Wu · Qingqing Hong · Yang Hao · Haiyu Yao · Yuanyuan Liang · Jiaqian Chen · Zhijun Shu · Man Wu · Shaohua Hu
Frontiers in Medicine
doi 10.3389/fmed.2026.1966449
Original Research
Published
Association of Serum GDF-15 with Bone and Muscle Parameters in Community-Dwelling Individuals
Nicia I. Profili · Sokratis Makrogiannis · Roberto Castelli · Maria Benelli · Valeria Orrù · Michele Marongiu · Edoardo Fiorillo · Francesco Cucca · Alessandro P. Delitala
Frontiers in Medicine
doi 10.3389/fmed.2026.1920342
Mini Review
Published
Biomarker-guided immunotherapy in osteosarcoma: from immune microenvironment profiling to patient stratification and combination strategies
Qingqing Li
Frontiers in Medicine
doi 10.3389/fmed.2026.1987146
Original Research
Published
Explainable machine learning for preoperative prediction of acute kidney injury after intertrochanteric fracture surgery in older adults
Weizhang Lin · Ximing Lin · Hongpeng Gao
Frontiers in Medicine
doi 10.3389/fmed.2026.1961926
Original Research
Published
Identification and validation of early vital sign trajectory subphenotypes for risk stratification in sepsis-associated liver injury: a multicenter retrospective cohort study
Weihang Wang · Jing Ma · Bingqing Wang · Jiayang Wang · Zexi Zang · Qiyao Liu · Zhi Gao · Wei Chen · Yuxin Deng · Zhiqing Zhang · Yongfang Jiang
Frontiers in Medicine
doi 10.3389/fmed.2026.1835574
Original Research
Published
Understanding ChatGPT adoption among medical students: an integrated theoretical model of psychological barriers and individual factors
Ayoob Lone · Ali Saleh Alshebami · Imtiyaz Ahmad Dar · Naved Iqbal
Frontiers in Medicine
doi 10.3389/fmed.2026.1945510
Original Research
Published
Clinical challenges in vaccine and monoclonal antibody development against ESCAPE pathogens: insights from EMA scientific advice procedures
Igor Stojkov · Linda Marchioro · Isabelle Bekeredjian-Ding · Benjamin Hofner
Frontiers in Medicine
doi 10.3389/fmed.2026.1931144
Systematic Review
Published
Effects of liraglutide on blood pressure and renal function in patients with type 2 diabetic nephropathy: a meta-analysis of randomized controlled trials
Shengning Gao · Yudong Shan · Dongxue Ma · Xiaohong Zhou · Weijuan Gao
Frontiers in Medicine
doi 10.3389/fmed.2026.1921737
Perspective
Published
Adapting the Girandole framework for cross-disciplinary social justice reflection in health professions education
Enrico De Luca · Bilkis Islam-Ali · Yusra Siddiqui
Frontiers in Medicine
doi 10.3389/fmed.2026.1942107