Review
Published
When absence becomes functional: lysine deserts in protein regulation and evolution
Natalia A. Szulc
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1959694
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Articles
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Showing 50 articles
Original Research
Published
Explainable machine learning integrating CT-derived intratumoral heterogeneity for histological subtype prediction in pure ground-glass lung adenocarcinoma: multicenter validation and transcriptomic characterization
Ying Deng · Jiajun Liu · Dinghua Li · Bingyi Zhang · Bin Xiang · Wanyin Qi · Sanhong Zhang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1958127
Opinion
Published
On the physics of chromatin molecular complex: from phase-separation to membrane adsorption
Andrea Fontana · Andrea M. Chiariello
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1951961
Original Research
Published
Development of a multiplex detection system for toxic Amanita species based on isothermal recombinase polymerase amplification and CRISPR/Cas12b technology
Hao Li · Xinyu Ying · Zhidan Luo · Chen Lu · Ping Zhang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1832406
Correction
Published
Correction: In vitro cytotoxic and pro-apoptotic effects of Lactobacillus rhamnosus GG cell-free supernatant on HT-29 colorectal cancer cells
Frontiers Production Office
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.2005518
Mini Review
Published
SIRT2 in metabolism, aging, and longevity
Menghui Li · Yihuan Dong · Wen Ren · Weixia Dong · Shaoping Ji
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1990670
Review
Published
Copper complexes in the triple-negative breast cancer landscape: advances and opportunities
Paula Marynella Alves Pereira Lima · André Carlos Pereira de Matos · Gabriela da Silva Guimarães · Laryssa Aparecida Sales Barbosa · Thaise Gonçalves Araújo
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1931263
Hypothesis and Theory
Published
Dimensional convergence at the nanoscale: a novel synthesis of experimental evidence justifying direct measurement of quantum coherence in microtubules
Justin Echternach
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1840116
Original Research
Published
Circulating and vascular NAD + metabolism remodeling in Tgαq*44 mice with progressive heart failure
Agata Jedrzejewska · Oliwia Krol · Patryk Mucha · Ada Kawecka · Ewa Slominska · Mariola Olkowicz · Ryszard T. Smolenski · Marta Tomczyk
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1927197
Original Research
Published
Immobilised enzyme reactors for post-production glycan modification of purified glycoproteins
Nicholas J. DeBono · Joel Cain · Chi-Hung Lin · Nicolle H. Packer · Edward S. X. Moh
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1932584
Correction
Published
Correction: Serum vitamins and microelements levels and their association with children with attention deficit hyperactivity disorder (ADHD)
Tianzhu Chen · Jiaxiong Yao · Yang Su · Jingya Li · Panli Tan
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.2008863
Review
Published
Molecular mechanisms regulating differential expression of individual miRNAs within polycistronic clusters
Diana Maltseva · Alexander Tonevitsky
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1913118
Systematic Review
Published
Cross-model metabolomic signatures of dietary anti-inflammatory (poly) phenols in nutraceutical development: a systematic review
Adesoji Fayomi · Emmanuel Adom · Alberta N. A. Aryee
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1824027
Original Research
Published
Serum GDF15 as a potential biomarker for treatment response and survival in patients with resectable locally advanced gastric cancer undergoing neoadjuvant chemotherapy
Can Cao · Shunda Wang · Shikang Ding · Hongyun Huang · Tian Yu · Moxi Chen · Yibin Xie · Jianchun Yu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1948454
Review
Published
Lipid droplet–mitochondria crosstalk in osteoarthritis: linking lipid routing to metabolic mismatch
Gang Meng · Ruijie Hou · Ping Dong · Qiannan Chen · Xueyuan Li · Kai Hu · Zixuan Du · Rong Wang · Zhaoxin Zhong
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1973436
Original Research
Published
AIPFusion-Net: an interaction-fusion framework for anti-inflammatory peptide prediction using protein language model embeddings, local sequence patterns, and handcrafted descriptors
Wentao Wang · Weidong Yang · Hongmei Li · Zhenyu Cui · Dan Shen
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1952395
Original Research
Published
Instillation timing as the main determinant of aqueous humor nepafenac exposure
Angelo Macri · Annalisa Salis · Margherita Tarallo · Michele Iester · Gianluca Damonte · Francesca Mattioli
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1913752
Original Research
Published
Integrated transcriptome and single-cell RNA sequencing identifies transient receptor potential channel-related biomarkers in ulcerative colitis
Tiantian Bao · Tianru Xie · Jiang Chen · Yibo Cao · Jian Zhu · Pingliang Sun · Tao Yang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1902447
Methods
Published
Full-protein release assay in a reconstituted yeast translation system using GGQ-methylated eRF1
Shuai Huang · Yichen Xu · Wenting Chen · Ziang Miao · Chang Liu · Riku Nagai · Muhoon Lee · Hitomi Seike · Shinji Nagata · Nono Takeuchi-Tomita
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1933983
Original Research
Published
Bacterial actin MreB as a new antibiotic target
Emőke Bódis · Beáta Longauer · András Lukács · Tamás Huber · Miklós Nyitrai · Géza Makkai · Tibor Jánosi · Rita Börzsei · Csaba Hetényi · Zoltán Gazdag · Szilvia Barkó
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1912759
Review
Published
Artificially intelligent modeling of macromolecular assemblies
Margherita Bini · Valentina Tozzini
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1856649
Review
Published
Exosomal microRNAs as biomarkers of multimorbidity risk in lean and obese women with polycystic ovary syndrome
Debarati Halder · P. V. Varshini · Tridip Mitra · A. H. Sruthi Anil Kumar · Piyush Agrawal · Mrinmoy Das · A. Senthil Kumar · R. Sajeetha Kumari · S. N. Meenakshi Sundari · Rajiv Janardhanan
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1868855
Original Research
Published
Discovery of metabolite biomarkers for cerebral ischemia-reperfusion injury based on metabolomics: neurotoxic mechanism and functional validation of a flavopiridol -related metabolite
Zhi-guang Song · Yu-chen Liu · Zhen-lin Zhong · Shu-ting Yin · Si-si Dai · Yi-di Zeng · Cai-xing Zheng · Si-yuan Chen · Ji-yong Liu · Yan-song Liu · Si-min Peng · Shi-min Tan · Qian-ru Zeng · Hua Li · Wang-hua Liu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1752337
Original Research
Published
Integrated bulk and single-cell transcriptomic analyses with experimental validation identify PLOD1 as a diagnostic biomarker and TGF-β1-responsive profibrotic mediator in dupuytren’s disease
Xianjie Lin · Mingming Wang · Yutian Lin · Yinshen Zhu · Zhijiang Ye · Haoran Chen
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1924451
Editorial
Published
Editorial: Cancer biomarkers: molecular insights into diagnosis, prognosis, and risk prediction: volume II
Matteo Becatti · Giuseppe Bronte · Shaoquan Zheng
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1999668
Review
Published
Gut microbiota–cancer crosstalk: emerging molecular targets for personalized cancer treatment- a comprehensive review
Pooja Negi · Arpita Upreti · Preeti Budhlakoti · Amit Kumar Sen · Mitali Danu · Sumit Tewari · Nirmal Joshi · Deepak Chandra Joshi
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1924197
Review
Published
Lipid droplet organized metabolic vulnerabilities in melanoma: from the MITF low state to ferroptosis sensitization
Mengzhen Chen · Yi Wu · Muxin Zhao
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1948743
Original Research
Published
Circulating arginine–nitric oxide pathway metabolites and nitrated fatty acids in relation to pathological features of colorectal cancer
Jakub Klekowski · Paulina Fortuna · Łukasz Lewandowski · Gabriela Maciejewska · Wioleta Szewczak · Karolina Mosna · Marek Zawadzki · Mariusz Chabowski · Mariusz Fleszar
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1910147
Review
Published
Understanding the strengths and limitations of recombinant protein studies
Daniele Dell’Orco · Karl-Wilhelm Koch
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1927411
Editorial
Published
Editorial: Metabolomic analysis of plant matrices: identification of compounds of therapeutic and nutraceutical interest
Mariacaterina Lianza · Victor Aguilar-Hernández
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1996217
Review
Published
Telomeric autophagy in human health, aging, and diseases
Xingyao Li · Xili Wu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1922188
Correction
Published
Expression of Concern: Butyrate suppresses glucose metabolism of colorectal cancer cells via GPR109a-AKT signaling pathway and enhances chemotherapy
Frontiers Editorial Office
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1993113
Review
Published
High-order chromatin structures mediated by phase separation in cell senescence
Wenjing Sun · Boxian Li · Zhaoyong Xu · Jing Wang · Jing Cao · Yangzhong Wang · Jiale Wang · Wenbo Gu · Pengjun Xu · Liang Wang · Wenyan Xie
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1896884
Original Research
Published
Single-cell transcriptomic analysis identifies vascular smooth muscle cell transcriptional programs associated with human carotid plaque remodeling
Yi-Jie Lu · Xue-Guang Lin · Ting Wang · Fan-Xuan Huang · Ying Deng · Shuai Jiang · Jing Dong Tang · Bo Yu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1950061
Original Research
Published
Integrated computational investigation of Glycosmis pentaphylla -derived compounds against major venom proteins of Daboia russelii
Sana S. Hussain · Danie J. Kingsley
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1906533
Review
Published
AI-driven multi-omics integration in breast cancer: clinical applications, immunotherapy prediction, and translational challenges
Zi-Yao Wang · Na Liu · Min-Bin Chen
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1875788
Original Research
Published
Development and evaluation of a machine learning based risk prediction model for osteoporosis
Lin Zhou · Qi Zhang · Haijing Wei · Jie Liu · Yongchang Yang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1939155
Original Research
Published
Preoperative CT deep learning of tumor and visceral adipose tissue combined with postoperative pathology predicts colorectal cancer recurrence: a multicenter study
Pengfei Wei · Linhua Zhong · Yongming Tan · Jinhong Zhao · Yongjie Zhou
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1937172
Original Research
Published
Integrative multi-omics characterization of KLRB1/CD161 in diffuse large B-cell lymphoma: associations with immune context, subtype biology, and therapeutic response
Erwei Li · Yingying Tang · Yuanyuan Wanyan · Yu Liang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1903725
Original Research
Published
Strengthening the interpretation of longitudinal EQA data through the sporadic inclusion of native human sera in general clinical chemistry
Laura Vierbaum · Patricia Kaiser · Ingo Schellenberg · Folker Wenzel · Mario Thevis · Manfred Falck
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1869542
Review
Published
Ferroptosis nanomedicine for cancer therapy: strategies and challenges
Yanpin Ma · Ziyi Xu · Hudabia Akram · Tiancheng Yang · Jiachun Sun · Xinyu Gu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1950781
Original Research
Published
Plasma untargeted metabolomics reveals metabolic signatures associated with epilepsy and anti-seizure medication responsiveness
Zijian Li · Zhen Liang · Juan Ren · Songyan Liu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1885513
Review
Published
Blood-based proteomics for schizophrenia: candidate biomarkers for risk assessment and precision psychiatry
Alexey S. Kononikhin · Anna E. Bugrova · Arina S. Foliforova · Maria I. Indeykina · Polina A. Strelnikova · Natalia V. Zakharova · Anna Y. Morozova · George P. Kostyuk · Evgeny N. Nikolaev
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1882675
Review
Published
Therapeutic reprogramming of natural killer cells for solid tumors: expanding frontiers into rare and ultra-rare malignancies
Francesca Rosato · James W. Hodge
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1955532
Original Research
Published
The impact of zeaxanthin and lycopene on fatty acid beta-oxidation in isolated peroxisomes from frozen livers of obese rats
Lina Baz · Mona Al-Thepyani
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1906904
Original Research
Published
Integrated bioinformatics and single-cell transcriptomics identify mitochondrial dysfunction-driven biomarkers for preeclampsia diagnosis
Lin Lin · Xiaowu Wang · Chengxiu Zhu · Kejun Ye · Dan Zhang · Ruohua Li · Mengjia Peng
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1922190
Original Research
Published
Integrative oxidative stress–disulfidptosis analysis identifies NPR3 and ZNF366 as cell-type-associated candidate markers in clear cell renal cell carcinoma
Ping Wang · Zhixuan Cai · Gaofeng Wu · Guangfeng Zhu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1912537
Perspective
Published
Development of an application for colorectal cancer prediction using SDC2 and TFPI2 methylation: an opportunity for early and noninvasive diagnosis in Latin-America
Fernando Hernandez-Medina · Alejandro Cornejo · Andrea Orue
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1922606