Articles

Showing 354 articles

• Case Report

  Published 12 October 2026

  Case Report: Longitudinal evaluation of cerebrospinal fluid Alzheimer’s disease core biomarkers in a case of refractory late-onset epilepsy of unknown etiology

  Takafumi Wada · Akira Kuzuya · Kazuma Koda · Sakiho Ueda · Atsushi Shima · Nobukatsu Sawamoto · Akio Ikeda · Ryosuke Takahashi · Riki Matsumoto

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1807027

• Review

  Published 12 October 2026

  Digital biomarkers derived from wearable and portable devices in prodromal Parkinson’s disease and at-risk populations: a scoping review

  Ting Yu · Qian Wang · Mingxia Pan · Yuanfang Xiong · Shiya Hu · Yiping Deng · Lingyu Kuang · Hanjiao Liu

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1850991

• Original Research

  Published 12 October 2026

  Inflammatory and cardiac-stress biomarkers in Moyamoya disease: the role of GDF-15

  Fengxia Guo · Hanxiao Li · Qiushi Guo · Yumeng Wang · Xiaohuan Zhang · Weiguang Luo

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1906016

• Review

  Published 12 October 2026

  The mind–body connection in women’s reproductive health: how psychological stress shapes gut and ovarian function - a narrative review

  Arpitha Yachanahalli Purushotham · Borehalli Mayegowda Shilpa · Divya Sundaram

  Frontiers in Gastroenterology

  doi 10.3389/fgstr.2026.1854862

• Original Research

  Published 12 October 2026

  Identification and validation of biomarkers related to oxidative stress in pediatric sepsis utilizing WGCNA and multiple machine learning algorithms

  Yumeng Liu · Gang Luo

  Frontiers in Bioinformatics

  doi 10.3389/fbinf.2026.1745381

• Original Research

  Published 12 October 2026

  Machine learning-based identification of CXCL13 and CXCL10 as key biomarkers in rheumatoid arthritis

  Subash M · Sheik Asraf S · Santhanamari M · Nagaraj P · Ayodeji Olalekan Salau · Abdullahi Garba Usman · Mouaz Yousfan

  Frontiers in Bioinformatics

  doi 10.3389/fbinf.2026.1925964

• Original Research

  Published 12 October 2026

  Levels of plasma PAD4 and citrullinated vimentin in relation to clinical severity of periodontitis and their exploratory discriminatory performance

  Weiwen Hu · Zhijia Xu · Xinyu Li · Xiaoyu Sun · Jiajie Tu

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1949560

• Clinical Trial

  Published 12 October 2026

  Quality of life and safety of a dietary intervention with French maritime pine bark extract (Pycnogenol ®) in women with osteoporotic bone loss: a randomized, placebo-controlled double-blind study—Part II

  Christian Scherg · Franca Genest · Jonas Maghary · Lothar Seefried · Petra Högger

  Frontiers in Nutrition

  doi 10.3389/fnut.2026.1924081

• Systematic Review

  Published 12 October 2026

  Outcome reporting in randomized trials of medicine–food homology interventions for cardiometabolic disease: a scoping review

  Jianguo Xu · Qingyong Zheng · Tengfei Li · Ming Liu · Min Tian · Yonghong Zhu · Yingying Kang · Jinhui Tian · Ping Chen

  Frontiers in Nutrition

  doi 10.3389/fnut.2026.1937261

• Review

  Published 12 October 2026

  Multi-omics insights into immune dysregulation and candidate biological programs in kawasaki disease: toward precision immunomodulation

  Yun Han · Jiaying Liu · Chengxu Song · Li Fu · Yu Gu · Yu Zeng · Zhenzhuang Zou

  Frontiers in Pediatrics

  doi 10.3389/fped.2026.1960681

• Review

  Published 12 October 2026

  Gut microbiota, microbial metabolites, and mucosal barrier dysfunction in benign anorectal disorders and ulcerative colitis: shared mechanisms, clinical links, and precision interventions

  Hexue Yuan · Maofang Zhao · Yunfen Wang · Chen Shen · Delong Liu · Chunxiao Wang · Jian Liu

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1979206

• Editorial

  Published 12 October 2026

  Editorial: Advances in early detection, pathophysiology, and management of mild cognitive impairment

  Edgar Vásquez-Carrasco · Cristian Sandoval-Vásquez · Pablo Valdés-Badilla

  Frontiers in Medicine

  doi 10.3389/fmed.2026.2007251

• Review

  Published 12 October 2026

  Spatial architecture shapes programmed cell death-associated immune niches and therapeutic resistance in clear cell renal cell carcinoma

  Yu Yin · Junlong Wang · Dengxiong Li · Dandan Qiu

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1952158

• Systematic Review

  Published 12 October 2026

  Imaging biomarkers related to 18F-FDG PET/CT for predicting microvascular invasion in hepatocellular carcinoma: a systematic review and meta-analysis

  Zhigang Li · Ke Gong · Ning Liu

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1948193

• Mini Review

  Published 12 October 2026

  Arsenic trioxide-induced cardiotoxicity: insights into the oxidative stress-inflammation positive feedback loop, translational biomarkers and targeted cardioprotective strategies— a narrative review

  Haiyan Wu · Jian Lv · Xiaoyang Hu

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1954263

• Perspective

  Published 12 October 2026

  From macrofungal polysaccharides to precision microbial immunotherapy: reprogramming the tumor microenvironment through immunometabolic and gene-regulatory pathways

  Kingsley Excel Dunga · Sylvester Chibueze Izah · Ebinyo Rebecca Aseibai · Matthew Chidozie Ogwu · Vivian Ibienebakabobo Promise · Nsikak Godwin Etim · Irene Nneka Ohanusi

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1966586

• Original Research

  Published 12 October 2026

  Efficacy and safety of immune checkpoint inhibitor plus bevacizumab-based chemotherapy in advanced or recurrent KRAS -mutant non-squamous NSCLC: the SPIRAL-STONE study

  Masaki Ishida · Tadaaki Yamada · Riko Kamada · Makoto Hibino · Masashi Egami · Takayuki Nakano · Tatsuya Imabayashi · Chieko Takumi · Koichi Ishida · Masafumi Takeshita · Ken Masubuchi · Miiru Izumi · Takayo Ota · Shoki Morito · Yusuke Chihara · Soichi Hirai · Shinsuke Shiotsu · Ryo Sawada · Hayato Kawachi · Naoya Nishioka · Masahiro Iwasaku · Koichi Takayama

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1875501

• Original Research

  Published 12 October 2026

  Upper respiratory virome signatures reflect COVID-19 severity and post-recovery shifts

  Mudita Gosain · Manjeet Kaur · Daizee Talukdar · Subhash Tanwar · Pradipta Jana · Sonali Porey Karmakar · Jyoti Verma · Susmita Bakshi · Kajal Kamboj · Priyanka Verma · Madhu Pareek · Sreevatsan Raghavan · Pallavi Kshetrapal · Shinjini Bhatnagar · Jayanta Bhattacharya · Pramod Kumar Garg · Nitya Wadhwa · Bhabatosh Das

  Frontiers in Microbiology

  doi 10.3389/fmicb.2026.1925299

• Review

  Published 12 October 2026

  TA-TMA as a clinical model for precision complement therapeutics in stem cell transplantation

  Sonata Jodele

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1959683

• Review

  Published 12 October 2026

  Immunometabolic crosstalk between dysfunctional adipose tissue and the brain: implications for postoperative cognitive dysfunction in obesity

  Ya-Jiao Hu · Juan Ni · Jin-Xi Zhang

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1965479

• Review

  Published 12 October 2026

  Glutamine metabolic reprogramming in acute and chronic kidney diseases: mechanistic insights and therapeutic implications

  Ruotong Xu · Jin Zhao · Minna Liu · Yifan Qiao · Xiaoxuan Ning · Shiren Sun

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1939528

• Review

  Published 12 October 2026

  Metabolic-epigenetic regulation of the HBV cccDNA reservoir: pathways underpinning viral persistence

  Qing Peng · Liyuan Hao · Shenghao Li · Fei Yu · Na Li · Fanghang Ye · Xiaoyu Hu

  Frontiers in Microbiology

  doi 10.3389/fmicb.2026.1968789

• Review

  Published 12 October 2026

  Tebentafusp induces systemic immune activation, but tumor immune remodeling remains incompletely validated: a narrative review in metastatic uveal melanoma

  Francesca Rifaldi · Filippo De Braud · Michele Del Vecchio · Lorenza Di Guardo

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1934256

• Review

  Published 12 October 2026

  Precision immuno-oncology in triple-negative breast cancer: from PD-L1 to multimodal biomarkers, ADC–ICI combinations, and global real-world integration

  Jingna Wu

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1911879

• Original Research

  Published 12 October 2026

  Early dynamics of eosinophils and the neutrophil-to-lymphocyte ratio are associated with severe immune-related adverse events during nivolumab therapy for metastatic renal cell carcinoma

  Ondřej Fiala · Jan Králíček · Jindřich Kopecký · Michal Vočka · Tomas Buchler · Hana Študentová · Jana Obertová · Beáta Rondzíková · Martin Matějů · Dominik Šafčák · Matej Hrnčár · Peter Priester · Martina Spisarová · Anežka Zemánková · Radka Lohynská · Michaela Tkadlecová · Lucie Grmelová · Petr Stránský · Bohuslav Melichar · Patrik Palacka · Alexandr Poprach

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1944728

• Original Research

  Published 12 October 2026

  Dried blood spot IP-10 as a biomarker of tuberculosis severity and treatment responses: results from a phase IIb trial of adjunctive acetylsalicylic acid and ibuprofen

  Iselin Høgbakk Edlund · Noelia Alonso-Rodriguez · Chiara Sopegno · Judith Farrés · Nino Gogichadze · Lilibeth Arias · Kaori L Fonseca · Kennedy Otwombe · Ziyaad Waja · Tumelo Moloantoa · Natasha Pillay · Thabiso Seiphetlo · Neil Martinson · Cristina Vilaplana · Anne Ma Dyrhol-Riise

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1924239

• Hypothesis and Theory

  Published 12 October 2026

  Economic impact of biomarker-based aging interventions on healthcare costs and individual value

  Federico Felizzi

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1814599

• Original Research

  Published 12 October 2026

  Cross-lineage anomaly detection of microRNA expression: a framework for deriving exploratory candidate biomarkers in sarcoma

  Mritunjoy Dey · Piotr Remiszewski · Ewelina Perdas · Paweł Golik · Jakub Piątkowski · Anna M. Czarnecka

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1907450

• Review

  Published 12 October 2026

  MicroRNA cargo of extracellular vesicles as mediators of immune dysregulation in pediatric immune thrombocytopenia: from pathogenetic drivers to biomarkers

  Lucia Argenziano · Maria Maddalena Marrapodi · Giuseppe Di Feo · Oriana Di Domenico · Francesca Rossi · Alessandra Di Paola

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1951187

• Review

  Published 12 October 2026

  Alcohol-induced placental vasculopathy reprograms the placental-fetal cardiovascular axis: angiogenic mechanisms linking maternal alcohol exposure to developmental cardiovascular programming

  Elisa Cebral

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1917947

• Review

  Published 12 October 2026

  Silencing without clearing: pharmacological modulation of the SASP in aging and disease

  Lukas Fresser · Zofia Chrienova · Jan Gebrt · Patrik Oleksak · Kamil Kuca · Eugenie Nepovimova

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1911529

• Review

  Published 12 October 2026

  Early life stress, lower urinary tract dysfunction, and respiratory disease: a proposed shared-mechanism framework

  Tadanobu Chuyo Kamijo · Mayoko Tsuji

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1929695

• Original Research

  Published 12 October 2026

  Independent correlates of vancomycin steady-state trough concentration among patients undergoing combined CABG and valve surgery: observational findings for intra-aortic balloon pump support

  Bei-bei Shao · Tao Feng · Ji-cheng Jiang · Wen-lu Xing · Ming Ni · Lu-lu Li · Chao Liu · Shu-ping Meng · Yong-cheng Ma · Ai-feng Wang

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1888382

• Review

  Published 12 October 2026

  WRN helicase addiction in MSI-H colorectal cancer: biomarker-guided pharmacology, resistance evolution, and implications for other gastrointestinal cancers

  Peng Zhang · Jiangsu Gan · Hongying Wang · Yali Xiong

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1962228

• Perspective

  Published 12 October 2026

  Precision targeting of type 2 inflammation in COPD: identifying candidates for dupilumab therapy

  Kezhuo Zhong · Kaiying Lv · Qun Liang

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1971309

• Systematic Review

  Published 12 October 2026

  Prognostic value of multiple biomarkers for kidney function decline in type 2 diabetes with relatively preserved kidney function: a systematic review and exploratory meta-analysis

  Jie Hu · Xinyu Pan · Shuwu Wei · Junping Wei

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1938521

• Review

  Published 12 October 2026

  Role of histone post-translational modifications in preeclampsia: from pathogenesis to diagnostic and therapeutic strategies

  Yuanxuan Ma · Renwei Zhang · Mengting Yang · Jingli Wang · Bo Hou · Shiguo Liu

  Frontiers in Endocrinology

  doi 10.3389/fendo.2026.1973542

• Editorial

  Published 9 October 2026

  Editorial: Imaging biomarkers in neurodegenerative diseases: advances and challenges

  Francesco Lanfranchi · Andrew R. Bender · Lucas Caldi Gomes

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.2009935

• Correction

  Published 9 October 2026

  Correction: Cerebrospinal fluid lipid profiles as exploratory biomarkers for pediatric meningitis: a proof-of-concept case series

  Feng Tang · Changzhen Li · Ye Zeng · Wanjun Luo · Lei Xi · Xiaomei Wang

  Frontiers in Cellular Neuroscience

  doi 10.3389/fncel.2026.2012403

• Review

  Published 9 October 2026

  Gene, microbiome, and anti-aging doping in sport: molecular mechanisms, detection strategies, and implications for sports rehabilitation medicine

  Diego Cotella

  Frontiers in Sports and Active Living

  doi 10.3389/fspor.2026.1984895

• Original Research

  Published 9 October 2026

  Evaluation of large language models for ICI-related liver injury with an emerging microbiome focus

  Man Sun · Dan Zang · Huan Zhou · Jun Chen

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1955356

• Review

  Published 9 October 2026

  Strategies for the detection and prevention of human cytomegalovirus from pregnancy to the neonatal period

  Pei Hu · Wenjie Chen · Ying Zhou · Mengyao Yu · Yuexinzi Jin · Xi Chen · Jiexin Zhang · Jin Zhou

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1965954

• Systematic Review

  Published 9 October 2026

  Effects and safety of acupuncture on inflammatory biomarkers in patients with coronary heart disease: a systematic review and meta-analysis

  Linghao Meng · Di Sun · Houfang Ma · Shuhan Zhao · Songyan Bai · Wenzeng Zhu · Limei Zhang · Shuai Shi

  Frontiers in Cardiovascular Medicine

  doi 10.3389/fcvm.2026.1891405

• Original Research

  Published 9 October 2026

  Prognostic value of the inflammatory burden index in predicting 1-year mortality in patients undergoing cardiac resynchronization therapy for heart failure

  Rustem Yilmaz · Kenan Toprak · Ahmet Karagoz · Osman Can Yontar · Mustafa Yolcu · Yasar Turan · Faruk Boyaci · Okan Oguzhan Ovaz · Emre Kasim Yilmaz · Enes Furkan Ozturk · Ersoy Öz

  Frontiers in Cardiovascular Medicine

  doi 10.3389/fcvm.2026.1934817

• Original Research

  Published 9 October 2026

  Comprehensive coronary computed tomography angiography assessment in high-altitude diabetic populations: integrating plaque characteristics, pericoronary inflammation, and coronary function

  Xin Fang · Shuang Li · Zhetao Wang · Junyan Zhang · Jia Song · Bing Wu · Kang Li · Kaiyue Diao

  Frontiers in Cardiovascular Medicine

  doi 10.3389/fcvm.2026.1886360

• Mini Review

  Published 9 October 2026

  Biomarker-guided immunotherapy in osteosarcoma: from immune microenvironment profiling to patient stratification and combination strategies

  Qingqing Li

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1987146

• Systematic Review

  Published 9 October 2026

  Effects of liraglutide on blood pressure and renal function in patients with type 2 diabetic nephropathy: a meta-analysis of randomized controlled trials

  Shengning Gao · Yudong Shan · Dongxue Ma · Xiaohong Zhou · Weijuan Gao

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1921737

• Systematic Review

  Published 9 October 2026

  From MRI-defined bone marrow lesions to pain, structural progression, and subchondral remodeling in knee osteoarthritis: an integrated multi-database bibliometric and text-mining analysis

  Yousheng Zhang · Zihang Zhao

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1903675