Review
Published
Application of large language models in early screening of Alzheimer’s disease: a scoping review
Jianan Tian · Weidong Huang · Yongmei Wen · Yifan Liang
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1906641
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Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 70 articles
Original Research
Published
Risk factors for invasive fungal infections after kidney transplantation and the construction of a predictive model
Lulu Tang · Jiqiu Wen · Hongdi Xiong · Chunying Lv · Jianhui Dong · Ning Wen · Guomei Huang · Zhiwen Jiang · Haiju Chen · Cairong Yan · Shuangshuang Li · Yuyang Jiang · Yi Wu · Cunwei Cao · Xuyong Sun
Frontiers in Medicine
doi 10.3389/fmed.2026.1850921
Original Research
Published
Deep-learning analysis suggests a facial image signal associated with low muscle mass in a clinical cohort enriched for chronic liver disease: a proof-of-concept study
Thomas Fuchs · Akhila Abdulnazar · Lavra Rebol · Peter Fickert · Thomas Gremsl · Vanessa Stadlbauer
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1964880
Original Research
Published
Physiologically-based pharmacokinetic model to predict pharmacokinetics of KY0467 in humans and guide dose selection in infants and children
Panpan Xie · Yanyan Yang · Xuemei He · Ming Yang · Zhixing Chen · Xi Weng · Aixin Shi
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1866331
Original Research
Published
Independent correlates of vancomycin steady-state trough concentration among patients undergoing combined CABG and valve surgery: observational findings for intra-aortic balloon pump support
Bei-bei Shao · Tao Feng · Ji-cheng Jiang · Wen-lu Xing · Ming Ni · Lu-lu Li · Chao Liu · Shu-ping Meng · Yong-cheng Ma · Ai-feng Wang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1888382
Original Research
Published
Clinical study of isokinetic training with joint control tasks on lower limb function in stroke patients with proprioceptive impairment: a preliminary randomized controlled trial
Zhendong Zhang · Huixian Yu · Ping Li · Na Li · Yumei Zhang
Frontiers in Neurology
doi 10.3389/fneur.2026.1881854
Systematic Review
Published
Towards optimizing repetitive transcranial magnetic stimulation protocols for chronic subjective tinnitus
Dibyendu Das · Koyel Das · Henry Benson Nongrum · Indranil Chatterjee · Dinesh Bhatia
Frontiers in Audiology and Otology
doi 10.3389/fauot.2026.1955517
Original Research
Published
TSC1-mTORC1 signaling in Alzheimer’s disease: an integrated bioinformatic analysis linking gene expression to neuropathology
Zheng Liu · Yuchen Yu · Yu Wang · Shuohan Ning · Tongshuai Huang · Jingqi Li · Sihan Fan · Chaolong Lu
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1920487
Original Research
Published
Development and temporal validation of a calibrated machine learning model for in-hospital blood culture positivity using routine clinical data
Tao Huang · Zhenzhen Tan · Longyang Jiang · Xuping Yang · Shurong Wang · Yilan Huang
Frontiers in Medicine
doi 10.3389/fmed.2026.1956921
Original Research
Published
Diverse Staphylococcus aureus lineages in a tertiary hospital in North Central Nigeria: emergence of CC1-ST772-MRSA, CC8-ST789-MRSA, and ST152-MRSA
Rasaki Adewole Raheem · Charles Nwabuisi · Abayomi Fadeyi · Bashirat Ayobola Olanipekun · Ademola Ibraheem Hamzat · Tomiwa Olumide Adesoji · Taofiq Adewale Sulayman · Alexander Mellmann · Frieder Schaumburg · Adebayo Osagie Shittu
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1908867
Original Research
Published
A machine learning model for predicting cognitive improvement after scalp cluster needling therapy in patients with post-stroke mild cognitive impairment
Yican Hao · Xia Wei · Pingli Zhao · Hewei Qin
Frontiers in Neurology
doi 10.3389/fneur.2026.1884682
Original Research
Published
Usability of digital medicine systems in patients with schizophrenia or schizoaffective disorder
Taishiro Kishimoto · Harumasa Takano · Ryo Kanzaka · Hisateru Tachimori · Hideki Oi · Hiroyuki Ogino · Kyosuke Sawada · Fumiaki Kumagai · Masayuki Tomita · Iku Nakayama · Yoshiyuki Shibasaki · Toshiaki Kikuchi · Hiroyoshi Takeuchi · Kazuyuki Nakagome
Frontiers in Psychiatry
doi 10.3389/fpsyt.2026.1903689
Review
Published
GLP-1 receptor agonists as potential disease-modifying agents in Parkinson’s and Alzheimer’s disease: mechanisms, clinical trial evidence, and the neuroprotection horizon
Mohamed Alsharif · Omran Shrebaty · Mohammad Ammar Aloudah · Mayar Alqahtani · Raghad Saud Aloubili · Marafi Jammaa Ahmed · Bana Albani · Ahmad El Bana
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1969490
Original Research
Published
Solving the mystery of persistent isolated aspartate aminotransferase elevation: Macro-AST as a decisive diagnostic consideration
Lina Sun · Yao Liu · Xue Yang · Fangyuan Gao · Lei Sun · Yu Lu · Yanqiu Li · Ying Feng · Xianbo Wang
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1895517
Original Research
Published
Prognosis and tumor grading in bladder urothelial carcinomas with intratumoral grade heterogeneity
Gökhan Veli Alkan · Kutsal Doğan · Meltem Türk Alkan · Evrim Önder
Pathology and Oncology Research
doi 10.3389/pore.2026.1612553
Original Research
Published
Gut microbiota and serum metabolomics in children with human parainfluenza virus infection
Xinghan Ren · Zhuoying Liu · Liuxuan Huang · Xiaotong Lai · Binyu Wu · Tianyu Bai · Xinyue Shen · Weijian Liang · Zhongting Dai · Huanqiong Li · Rong Zhou · Tiantian Liu
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1941674
Systematic Review
Published
A systematic review to characterize functional tic-like behaviors
Joseph B. Gary · Jacob S. Shaw · Joseph F. McGuire
Frontiers in Child and Adolescent Psychiatry
doi 10.3389/frcha.2026.1936806
Systematic Review
Published
Artificial intelligence, explainable deep learning, and generative models for osteoporosis and bone disease prediction: a systematic review and future research roadmap
M. Raja · Avulapalli Jayaram Reddy
Frontiers in Artificial Intelligence
doi 10.3389/frai.2026.1930437
Original Research
Published
No evidence that serum metabolite slopes improve held-out prediction of clinical progression in the Alzheimer’s disease neuroimaging initiative
Tia Warrick · Manali Misra · Stephen Kataria · Jahnavi Patel · Bhuvi Ajmera
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1942662
Original Research
Published
Prediction of cognitive impairment in Parkinson’s disease using TabPFN: an integrative analysis of clinical data, longitudinal trajectories, and lipidomics
Zikai Zhou · Jie Liu · Lijuan Wang · Hong Lv · Wencan Jiang · Ling Huang · Guojun Zhang · Ruimin Ma
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1905374
Methods
Published
Investigation into biomarkers to predict preterm birth (INSIGHT): a longitudinal UK pregnancy cohort for spontaneous preterm birth research
Raphaella Jackson · Carlotta Valensin · Evonne Chin-Smith · Natalie Suff · Andrew H. Shennan · Natasha L. Hezelgrave · Rachel M. Tribe
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1926506
Original Research
Published
Cellular, chromatin-accessibility, and spatial contextualization of bulk transcriptional patterns linked to positive peritoneal cytology in endometrial cancer
Jiangang Huang · Binglai Luo · Zhiqing Hu · Shuping Lin · Jinyong Wang · Meiyan Lin
Frontiers in Genetics
doi 10.3389/fgene.2026.1924936
Original Research
Published
Development and evaluation of a machine learning based risk prediction model for osteoporosis
Lin Zhou · Qi Zhang · Haijing Wei · Jie Liu · Yongchang Yang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1939155
Original Research
Published
An XGBoost–logistic regression hybrid stacking model for breast cancer outcome prediction
Oyetayo Oyebisi · Winnie Chacha · Femi Amoyedo
Frontiers in Applied Mathematics and Statistics
doi 10.3389/fams.2026.1931146
Original Research
Published
CERKL- related inherited retinal dystrophy in a Brazilian cohort: genotype-phenotype correlation
E. S. Yasaki · M. V. Salles · F. L. Motta · J. M. F. Sallum
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10935
Original Research
Published
Retrospective analysis of ustekinumab in Crohn’s disease between biologic-naïve and biologic-experienced
Kaifei Yuan · Xianhong Hu · Qi Fang · Siyuan Li · Ping Lin · Baijing Ding · Tongyuan Lin
Frontiers in Gastroenterology
doi 10.3389/fgstr.2026.1926425
Brief Research Report
Published
Routine baseline clinical data do not reliably predict poor first-year myopia control with low-dose atropine: a machine-learning benchmarking study
Karenna Mehta · Robert A. Clark
Frontiers in Ophthalmology
doi 10.3389/fopht.2026.1930814
Review
Published
Hearing preservation in cochlear implantation: a comprehensive review with emphasis on atraumatic and robot-assisted electrode insertion
Guillaume Gersdorff · Severine Camby · Philippe Lefebvre
Frontiers in Audiology and Otology
doi 10.3389/fauot.2026.1939453
Opinion
Published
Ten key considerations for developing interpretable risk prediction models
Xi Zhang · Wenjie Xu · David R. Smith
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1878681
Original Research
Published
Palmitoylation-related lncRNAs link molecular signaling, immune remodeling, and tumor progression in glioma: prognostic modeling and functional validation of LYRM4-AS1
Juan Xu · Chen Zhang · Lingling Pu · Xiaoyang Zhu · Xiaoan Sheng · Juanjuan Dong · Miaomiao Song · Chao Wang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1901839
Review
Published
Narrative review of intravenous NAD + and NAD + precursors in wellness and translational medicine
Abdulrahman Alangari · Jamal Arif · Fahd Al Qureshah · Fahad Alkhodairy
Frontiers in Aging
doi 10.3389/fragi.2026.1887175
Original Research
Published
Guanfacine extended-release use in diagnostic diversity and symptom complexity
Gülenay Korkmaz Şahin · Seda Sarı · Zeynep İrem Şener · Nazlı Burcu Özbaran
Frontiers in Child and Adolescent Psychiatry
doi 10.3389/frcha.2026.1912093
Original Research
Published
Breastmilk transfer and infant exposure to atazanavir/ritonavir in breastfeeding women with HIV: results from IMPAACT 2026
Emily Anne Barr · Mauricio Pinilla · Jeremiah D. Momper · Ahizechukwu C. Eke · Lucy Koech · Kristina M. Brooks · Victoria Ndyanabangi · Sandra K. Burchett · Sujith Valiyaparambil · Mark Mirochnick · Alice Marie Stek · Brookie M. Best · Rachael Jeffrey · Chelsea Stotz · Marije Van Schalkwyk · Renee Browning · David E. Shapiro · Kathleen M. Powis
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1892081
Original Research
Published
Adverse drug events in hospitalized COVID-19 patients: a pharmacovigilance perspective on ICU management and fentanyl exposure
Michele Ferreira Murgel · Marcel de Souza Borges Quintana · Roberta Olmo Pinheiro · Vítor Santos da Silva · Cláudia Luciana dos Santos Moura · Vanessa da Gama Oliveira · Cláudia Maria Valete Rosalino · Gilberto Marcelo Sperandio da Silva
Frontiers in Epidemiology
doi 10.3389/fepid.2026.1770145
Methods
Published
Dissecting and stimulating instruments in thyroid surgery: principles, applications and clinical role
Francesco Brucchi · Carla Colombo · Giuseppe Mercante · Paolo Battaglia · Pietro Indelicato · Diego Barbieri · Davide Lombardi · Gabriele Materazzi · Gianlorenzo Dionigi
Frontiers in Medical Technology
doi 10.3389/fmedt.2026.1845958
Review
Published
Non-coding RNAs as predictive factors of oncological outcomes in plasma cell myeloma
Alicja Bogdanowicz-Żeleźniak · Natalia Moniczewska · Maciej Korpysz · Aneta Szudy-Szczyrek · Radosław Mlak
Oncology Reviews
doi 10.3389/or.2026.1868835
Original Research
Published
Longitudinal deep learning-based segmentation of multiple sclerosis lesions in a local clinical cohort
Amalie Monberg Hindsholm · Annika Reynberg Langkilde · Jette Lautrup Frederiksen · Flemming Littrup Andersen · Henrik B. W. Larsson · Ulrich Lindberg · Claes Nøhr Ladefoged
Frontiers in Radiology
doi 10.3389/fradi.2026.1758276
Original Research
Published
Intelligent data governance and quality control for chest Bi syndrome/coronary heart disease across the prevention–treatment–rehabilitation continuum: integrating a standardized framework, adversarially-optimized trigger engine, and domain-adaptive AI
Huisi Hong · Guiyuan Yang · Weihan Shen · Shiqi Luo · Yiming Yuan · Yong Zhao · Hong Zhang · Shuangyan Li · Juhua Wu · Wenge Chen · Shaoyang Men · Kaixuan Lin
Frontiers in Medical Technology
doi 10.3389/fmedt.2026.1759773
Original Research
Published
Cost-utility analysis of home treatment versus inpatient treatment in child and adolescent psychiatry: a decision analysis
Karolina Foremnik · Gaby Sroczynski · Barbara Buchberger
Frontiers in Child and Adolescent Psychiatry
doi 10.3389/frcha.2026.1923381
Original Research
Published
Admission direct bilirubin and direct bilirubin-to-lymphocyte ratio as exploratory markers of early severity and in-hospital functional status in acute ischemic stroke
Yingxia Li · Ruixing Zhang · Yang Luo · Youquan Gu
Frontiers in Stroke
doi 10.3389/fstro.2026.1800285
Original Research
Published
A comparative performance analysis of ensemble learning and regularized neural networks in cardiovascular risk prediction
Golam Md Mohiuddin · Md Shakil Hossain · Md Shohel Sayeed
Frontiers in Medical Technology
doi 10.3389/fmedt.2026.1902471
Original Research
Published
Diagnostic delay, SERPING1 allelic heterogeneity, and real-world lanadelumab prophylaxis in Chinese patients with hereditary angioedema due to C1 inhibitor deficiency
Wenjin Du · Siqin Wang · Ke Yang · Qiuxing Zhang · Xianghua Lin · Wenchao Zhang · Weili Guo
Frontiers in Allergy
doi 10.3389/falgy.2026.1899305
Review
Published
Environmental DNA and next-generation sequencing for post-elimination surveillance of neglected tropical diseases in the Philippines and the Western Pacific Region
Boonfei Tan · Su Yin Lim · Josephine Abrazaldo · Patrick De Vera · Charmaine Ng
Frontiers in Tropical Diseases
doi 10.3389/fitd.2026.1829146
Original Research
Published
Hepatitis E virus infection in kidney transplant recipients: a pilot cross-sectional study of serological markers and allograft function in Northern Serbia
Sonja B. Golubović · Jelena D. Stojčević Maletić · Lada V. Petrović · Tamaš R. Petrović · Violeta V. Knežević · Maja S. Ružić
Frontiers in Nephrology
doi 10.3389/fneph.2026.1864349
Review
Published
Research advances on acute kidney injury and brain dysfunction
Min Li · Xiaohui Liao · Jingyang Ran
Frontiers in Nephrology
doi 10.3389/fneph.2026.1867473
Review
Published
Personalised prevention and management of kidney stones: a narrative review on the importance of integrating environmental, social and genetic factors
Aleksandra Leonova · Rosa Sinisi · Stefano Alba · Vincenzo Andracchio · Alberto Piana · Carmela Leonessa · Giuseppina Rose · Vito Summa · Giuseppe Passarino · Paolina Crocco
Public Health Reviews
doi 10.3389/phrs.2026.1609208
Perspective
Published
Artificial intelligence to enhance research integrity in evidence-based medicine: toward scalable trustworthiness assessment
Moses Mo · Rohit Arora · Christian Cao · Andrea C. Tricco · David Moher
Frontiers in Research Metrics and Analytics
doi 10.3389/frma.2026.1833223
Original Research
Published
Early identification of PRISm from chest CT: a multimodal for three-class stratification of normal, PRISm, and COPD
Yan Mou · Xueqing Bian · Na Tian · Zheng Xia · Jinbo Shi · Ming Li · Zhimin Shao · Lin Qi · Haiyan Ge · Miao Huang
Frontiers in Radiology
doi 10.3389/fradi.2026.1829853