Articles

Showing 178 articles

• Perspective

  Published 12 October 2026

  Shared mediators, divergent networks: a tissue-response hypothesis for discordant phenotypes in chronic spontaneous urticaria and atopic dermatitis

  Young-Min Ye · Michihiro Hide

  Frontiers in Allergy

  doi 10.3389/falgy.2026.1976519

• Original Research

  Published 12 October 2026

  Antimicrobial resistance of bacteria isolated from blood cultures at a tertiary hospital in Papua New Guinea: implications for antimicrobial stewardship and surveillance

  Watson Toroi · Victor Musyoki · Becky Max · Donella Omena · Nomvuyo Mothobi · Kudakwashe Chani · Josephine Chanoan · Amrita Ronnachit

  Frontiers in Public Health

  doi 10.3389/fpubh.2026.1914935

• Original Research

  Published 12 October 2026

  A comparison of clinical phenotype and outcomes in anti- melanoma differentiation-associated protein 5 dermatomyositis and anti-synthetase syndrome in a multiethnic cohort in Singapore

  Choon-Guan Chua · Zhaoxiang Fan · Hwee-Pin Phua · Wei-Yen Lim · Gin Tsen Chai · Mona Manghani

  Frontiers in Medicine

  doi 10.3389/fmed.2026.1969582

• Hypothesis and Theory

  Published 12 October 2026

  Influencing the exposome, patient macroenvironment, tumor microenvironment through-line to improve clinical outcomes

  Samuel F. Yanuck · Neil E. Alexis

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1929067

• Correction

  Published 12 October 2026

  Correction: Genetically defined systemic autoinflammatory diseases in pediatric patients with Behçet’s disease

  Shaoling Zheng · Pui Y Lee · Qing Zhou · Xu Han · Xuechan Huang · Yukai Huang · Jiajun Chen · Chun Zheng · Xiaolin Fang · Jianhua Yu · Aiwu Wang · Xia Pan · Xiaomin Yu · Tianwang Li

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.2007295

• Original Research

  Published 12 October 2026

  House dust mite drives biphasic immunomodulation of inflammatory dendritic epidermal cells via glucose metabolism in atopic dermatitis

  Ying Zhao · Cuie Gao · Xin Sui · Lan Ge · Huan Wang · Sisi Deng · Qiquan Chen · Lu Liu · Jing Tian · Tong Mu · Li Wang · Zhiqiang Song

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1887390

• Review

  Published 12 October 2026

  CAR-T-cell therapy for autoimmune neurologic diseases

  Yunhan Zhao · Yunyu Ding · Congfeng Tang · Zhengrong Wei · Yuqing Fan · Xianhui Hu · Jilong Yi

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1942249

• Mini Review

  Published 12 October 2026

  Cerebrospinal fluid metagenomic next-generation sequencing for culture-negative anaerobic central nervous system infection involving Prevotella oris : attribution challenges in low-biomass specimens

  Yan Li · Minghua Fan · Yuyuan Hu · Yuhang Yang · Wenyuan Li · Wei Zhang · Yanhong Wang

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1896093

• Original Research

  Published 12 October 2026

  An opsonic peptide promotes radiation-induced macrophage extracellular trap clearance to alleviate inflammation

  Yongchan Lee · Gaifeng Ma · Dilara Aylar · Monowar Aziz · Ping Wang

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1970645

• Original Research

  Published 12 October 2026

  SCD1 inhibition promotes lipid peroxidation and enhances anti-PD-1 response in triple-negative breast cancer

  Quentin Herrera Garfia · Aurélien Azam · Eric Bonneil · Laetitia Montero-Ruiz · Mohsen Momeni · Mohammad Farran · Robin Jehay · Nor Eddine Sounni

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1843935

• Original Research

  Published 12 October 2026

  Spatial analysis of placentae during congenital cytomegalovirus infection suggests distinct cellular profiles in immune and trophoblast cells: an exploratory study

  Elise Sintim-Aboagye · Huy Quang Quach · Indrani Mukherjee · Will Sherman · Katelyn T. Nguyen · Neil Ferland · Sheila Farnan · Kamila Otrubova · Namisha Verma · Dawn Littlefield · Sohan Punia · Erica Johnson · Mark Blackstad · Mark R. Schleiss · Andrew P. Norgan · Clive M. Gray · Elizabeth Ann L. Enninga · Rana Chakraborty

  Frontiers in Immunology

  doi 10.3389/fimmu.2026.1885923

• Review

  Published 9 October 2026

  The global emergence of Trichophyton indotineae: epidemiology, resistance, and management challenges

  Dipika Shaw · Adnan Omar · Michelle Singh · Merin Chandanathil · Chandana Bhargavi · Nagaraj Mysore · Dharam Bir · Srinidhi Ramasamy · Prasanna Honnavar

  Frontiers in Tropical Diseases

  doi 10.3389/fitd.2026.1960706

• Original Research

  Published 9 October 2026

  Establishing standardized evaluation protocols for peptide-target interaction prediction: the PTI-TAPE consensus framework eDelphi

  William J. Waldock · Guangshun Wang · Ara Darzi · Cesar de la Fuente-Nunez · Hutan Ashrafian · the PTI-TAPE Consortium Committee

  Frontiers in Bioinformatics

  doi 10.3389/fbinf.2026.1894725

• Original Research

  Published 9 October 2026

  Clinical reasoning in canine meningoencephalitis of unknown origin and glioma: the role of signalment, history and neurological examination

  Franziska Spohn · Samira Abani · Peter J. Dickinson · Karen M. Vernau · Christine M. Toedebusch · Kevin D. Woolard · Andreas Beineke · Holger A. Volk · Jasmin N. Nessler

  Frontiers in Veterinary Science

  doi 10.3389/fvets.2026.1920683

• Original Research

  Published 9 October 2026

  Age-related hepatic tolerance to ischemia-reperfusion injury in a rat model of extended hepatectomy

  Dmitry G. Akhaladze · Ivan V. Tverdov · Alexander A. Andreev-Andrievskiy · Mikhail A. Mashkin · Olga Yu. Frolova · Nikolay S. Grachev

  Frontiers in Surgery

  doi 10.3389/fsurg.2026.1902759

• Original Research

  Published 9 October 2026

  Tumor-antigen-specific polyclonal antibodies suppress tumor growth and metastasis in heterogeneous solid tumors

  Carine Ciron · Ophélie Dauphouy · Pierre Morice · Pierre-Joseph Royer · Gwenaëlle Evanno · Juliette Rousse · Françoise Shneiker · Bernard Vanhove · Odile Duvaux · Firas Bassissi

  Frontiers in Oncology

  doi 10.3389/fonc.2026.1947593

• Original Research

  Published 9 October 2026

  An experimentally validated manually curated genome-scale metabolic model of Enterococcus faecium TX0016 reproduces high-throughput phenotyping data

  Dina Samir Rasmi · Kalpathy Jayanth Krishnan · Yomna A. Hashem · Bernhard O. Palsson · Mona T. Kashef · Jonathan M. Monk · Ramy K. Aziz

  Frontiers in Microbiology

  doi 10.3389/fmicb.2026.1941652

• Original Research

  Published 9 October 2026

  Whole-genome sequencing analysis of phylogenetic relationships and lineage diversity of Mycobacterium tuberculosis in Western Kenya

  Susan Musau · Eleanor I. Lamont · Victor Moses Musyoki · Susan Odera · Noel Onyango · Steve Wandiga · Inosters Wambua Nzuki · Bob Morrison · Reymond Mumo · David Sherman · Marianne W. Mureithi · Videlis Nduba

  Frontiers in Microbiology

  doi 10.3389/fmicb.2026.1980516

• Review

  Published 9 October 2026

  Gut microbiota-immune-bone axis in osteoporosis: mechanisms and intervention strategies

  Minying Huang · Baocheng Xie · Hongyu Liu

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1879472

• Mini Review

  Published 9 October 2026

  Distinct host genetic determinants of HIV acquisition and disease progression: the case of classical HLA class I

  Marion Amujal · James Bumba

  Frontiers in Genetics

  doi 10.3389/fgene.2026.1982540

• Review

  Published 9 October 2026

  Treatment of myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): acute attacks, relapse prevention, and symptomatic care

  João Vitor Mahler · Marina Vilardo · Guilherme Diogo Silva · Anastasia Vishnevetsky · Philippe-Antoine Bilodeau · Michael Levy · Marcelo Matiello

  Frontiers in Neurology

  doi 10.3389/fneur.2026.1965135

• Original Research

  Published 9 October 2026

  The relationship between potential categories of self-management behavior and disease knowledge level of gout patients based on K-means clustering analysis

  Zuoyun Ma · Xia Pan · Tianwang Li · Yali Wang · Chun Zheng · Li Tang

  Frontiers in Psychology

  doi 10.3389/fpsyg.2026.1951213

• Review

  Published 9 October 2026

  Application of natural products combined with plant-derived extracellular vesicles in cancer therapy

  Ruyue Wang · Menglin Ren · Yuanjian Xu · Yan Sun · Zenghui Xu

  Experimental Biology and Medicine

  doi 10.3389/ebm.2026.11329

• Case Report

  Published 8 October 2026

  Case Report: Application of the 6D BTS digital assessment system in the comprehensive management of refractory cancer pain in a patient with gallbladder carcinoma

  Jing Ren · Yuewen Li · Kunzhong Zhou · Yunhua Wang · Quanli Wang · Dongmei Hu · Tingting Song · Hui Dong · Zhijuan Cheng · Changrong Hu · Kunxiang Huang · Yuan Zhang · Li Zhuang

  Frontiers in Pain Research

  doi 10.3389/fpain.2026.1808441

• Original Research

  Published 8 October 2026

  Characterizing and mitigating protocol-dependent gene expression bias in 3′ and 5′ single-cell RNA sequencing

  Valeryia Shydlouskaya · S. M. Mansour Haeryfar · Tallulah S. Andrews

  Frontiers in Bioinformatics

  doi 10.3389/fbinf.2026.1931243

• Perspective

  Published 8 October 2026

  From disease activity scores to precision medicine: biomarkers and composite models for risk stratification in chronic spontaneous urticaria

  Shuayb Elkhalifa · Mohamed Abuzakouk

  Frontiers in Allergy

  doi 10.3389/falgy.2026.1962595

• Review

  Published 8 October 2026

  Leishmaniasis and vaccine development: current progress, challenges, and future perspectives

  Somaditya Dey · Anushka Ghosh · Debarati Mukherjee

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1929424

• Review

  Published 8 October 2026

  Candida albicans subverts host programmed cell death: a unified framework from pyroptosis to ferroptosis

  Limin Fan · Ruining Huang · Kexin Wang · Manting Ni · Xiuyu Nong · Zhenmou Xie · Bo Fu · Lijun Mo · Yinyuan Lan · Qingqing Xu · Wenhan Cao · Xinyue Li · Xueting Liu · Yaohua Xue

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1960578

• Systematic Review

  Published 8 October 2026

  Mapping the intellectual landscape of lactylation research: a bibliometric analysis of global trends and emerging frontiers

  Jieyan Wang · Zhou Li · Xiya Li · Xiyu Liu · Zhaohua Zhong · Yantong Wan · Hui Liang

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1841236

• Systematic Review

  Published 7 October 2026

  Biologics and JAK inhibitors for atopic manifestations in inborn errors of immunity: a systematic review

  Mahnaz Jamee · Roba Maher Al-Gaweesh · Amirhossein Hajialigol · Sally Gouda Mohammed · Peyman Tirandazi · Abdullah A. Alangari · Rasha El-Owaidy

  Frontiers in Allergy

  doi 10.3389/falgy.2026.1867183

• Original Research

  Published 7 October 2026

  Variable alterations in frequencies of CRISPR/Cas9-induced nucleotide deletion and insertion in transgenic maize callus tissues exposed to chromatin modifiers

  Bettina Nagy · Aysha Jameel · Gábor V. Horváth · Katalin Török · Ferhan Ayaydin · Nikolett László · Divya Teja Dondapati · Sándor Mórocz · Zoltán Zombori · Györgyi Ferenc · Dénes Dudits

  Frontiers in Genome Editing

  doi 10.3389/fgeed.2026.1924094

• Brief Research Report

  Published 7 October 2026

  The pathogenic role of high-titer anti-Ro52 antibodies in neonatal lupus erythematosus: insights from a 9 case series

  Shuo Cheng · Yi Jiang · Suo Zhang · Jiaming Huang · Xiaoxue Wang · Huanyu Xie · Meiying Wang

  Frontiers in Pediatrics

  doi 10.3389/fped.2026.1939494

• Review

  Published 7 October 2026

  Phthalates: the interplay between diet, obesity, diabetes, and gut microbiota

  Luiza Czaczkowska · Natalia Radziwon · Klaudia Sikorska · Edyta Olkowska · Ewa Jabłońska · Wioletta Ratajczak-Wrona

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1941846

• Original Research

  Published 7 October 2026

  A CAR/CD19 Jurkat cell model for bioprocess screening and expansion: potential use for CAR-T cells production

  Hugo E. Fuentes-Bustos · Alejandrina Hernández-López · Marta Zapata-Tarrés · Juan Carlos Bustamante-Ogando · Blanca Angélica Segura-Pacheco · Alberto Olaya-Vargas · Angélica Meneses-Acosta

  Frontiers in Bioengineering and Biotechnology

  doi 10.3389/fbioe.2026.1917849

• Clinical Trial

  Published 6 October 2026

  An intravaginal ring for HIV pre-exposure prophylaxis: assessment of safety and pharmacokinetics in a randomized, placebo-controlled clinical trial

  Kathleen L. Vincent · John A. Moss · Mark A. Marzinke · Richard B. Pyles · Lauren Dawson · Trevelyn J. Olive · Irina Butkyavichene · Amalia E. Castonguay · John M. Cortez · Mariana Remedios-Chan · Patricia Galvan · Sofia Rivera · Simon Webster · Manjula Gunawardana · Amy P. Adler · Christina M. Ramirez · Hans M. L. Spiegel · Craig W. Hendrix · Peter A. Anton · Marc M. Baum

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1955105

• Original Research

  Published 6 October 2026

  Adverse childhood experiences and functional stability in the affective-to-psychotic spectrum: a longitudinal multistate analysis of employment and relationship outcomes

  Fanny Senner · Elena Merkle · Michael Lauseker · Eva C. Schulte · Urs Heilbronner · Monika Budde · Daniela Reich-Erkelenz · Mojtaba Oraki Kohshour · Alba Navarro-Flores · Maria Heilbronner · Ion-George Anghelescu · Volker Arolt · Bernhard T. Baune · Detlef E. Dietrich · Andreas J. Fallgatter · Christian Figge · Markus Jäger · Georg Juckel · Carsten Konrad · Nathalie Kühnen · Eva Z. Reininghaus · Max Schmauß · Andrea Schmitt · Simon Senner · Carsten Spitzer · Alkomiet Hasan · Peter Falkai · Thomas G. Schulze · Kristina Adorjan · Sergi Papiol · Sophie-Kathrin Greiner

  Frontiers in Psychiatry

  doi 10.3389/fpsyt.2026.1930635

• Original Research

  Published 5 October 2026

  Molecular epidemiology of carbapenemase-producing gram-negative bacilli in diabetic foot infections: association with glycemic control

  Gamal Othman · Abdelnaser A. Badawy · Rasha Hamed Al-Serwi · Maysaa El Sayed Zaki · Noha Tharwat Abou El-khier · Nashwa M. Alkassaby · Mohamed Saleh Ismail

  Frontiers in Cellular and Infection Microbiology

  doi 10.3389/fcimb.2026.1847743

• Review

  Published 5 October 2026

  The aryl hydrocarbon receptor and kynurenine pathway: connecting inflammatory bowel disease and depression via the microbiota gut brain axis

  Raymond Bogdon · Kasie Roark · Philip Brandon Busbee

  Frontiers in Neuroscience

  doi 10.3389/fnins.2026.1851943

• Perspective

  Published 2 October 2026

  Hydrogen gas and olfactory dysfunction in Alzheimer’s disease: the Hydrogen–Olfactory–Limbic hypothesis

  Ligao Bao · Dunfu Eer

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1937419

• Clinical Trial

  Published 2 October 2026

  Impact of contraceptive initiation on the cervicovaginal mucosa: results from the UMPALA multicentre, partially randomized patient-preference interventional trial

  Betty Njoroge · Nelly Mugo · Carolina Herrera · Karen Dominguez · Louise A. Ouattara · Nazita Yousefieh · Neelima Chandra · Agnieszka Kurczewska · Stephanie Nartey · Julie Lewis · Andrea R. Thurman · Matilda Saina · Raina N. Fichorova · Jacques Ravel · Reem Sharaf Alddin · Nicola Richardson-Harman · Kenneth Ngure · Gustavo F. Doncel

  Frontiers in Reproductive Health

  doi 10.3389/frph.2026.1882772

• Original Research

  Published 2 October 2026

  Vacuole histomorphology characteristics and their same immunophenotype with the gut wall: A histological study using human fetuses

  Xuelai Liu · Zhe-Wu Jin · Yuqiang Chen · Mao Ye · Feng He · Xiaoyun Cui · Huan Wang · Chaosheng He

  Frontiers in Pediatrics

  doi 10.3389/fped.2026.1915639

• Original Research

  Published 2 October 2026

  Methylglyoxal hampers the angiogenic capacity of human retinal endothelial cells modifying cell transcriptome with the contribution of NRSF/REST

  Marianna Aprile · Cecilia Nigro · Caterina Perfetto · Alessia Leone · Simona Cataldi · Antonella Nicolò · Mariagiovanna Tramontano · Antonella Desiderio · Francesco Beguinot · Valerio Costa · Claudia Miele · Alfredo Ciccodicola

  Frontiers in Cell and Developmental Biology

  doi 10.3389/fcell.2026.1762167

• Original Research

  Published 1 October 2026

  Evaluation of real-time LAMP assay for detection of Entamoeba species in clinical stool samples from a tertiary care center in North India

  Devyani Sharma · Usha Dutta · Divya Rattan · Upninder Kaur · Shinichi Inoue · Shinjiro Hamano · Ruby Jain · Kawaljeet Singh Sandha · Rakesh Sehgal · P. V. M. Lakshmi

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1937802

• Perspective

  Published 1 October 2026

  Beyond the embryo: reframing recurrent implantation failure through immunopriming and endometrial immune dysregulation

  Jayesh Amin

  Frontiers in Reproductive Health

  doi 10.3389/frph.2026.1892030

• Original Research

  Published 30 September 2026

  Hemocompatible polymeric hydrogels with tunable photoresponsive volumetric properties

  Akari J. Seiner · Victor Mishin · Shreya S. Soni · Elisabeth Posthill · Biplab Sarkar · Kara L. Spiller · Amy L. Throckmorton · Christopher B. Rodell

  Frontiers in Biomaterials Science

  doi 10.3389/fbiom.2026.1924191

• Original Research

  Published 30 September 2026

  Protoberberine alkaloids berberine and palmatine employ Pf Pgh-1 transporter to enter the digestive vacuole and kill the malaria parasite by inhibiting heme biocrystallization

  Nekpen Erhunse · Prachi Tomar · Dinkar Sahal · Agam Prasad Singh

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1949463

• Methods

  Published 30 September 2026

  Protocol for non-viral HDR-based CRISPR/Cas9 platform for small custom editing in primary T cells

  Katariina Mamia · Anniken Solveig Matheson Sollano · Vanja Lundberg · Svetlana Vakkilainen · Eliisa Kekäläinen · Camilla Schalin-Jäntti · Eira Leinonen · Børre Fevang · Juha Grönholm · Timi Martelius · Shiva Dahal-Koirala · Emma Maria Haapaniemi

  Frontiers in Genome Editing

  doi 10.3389/fgeed.2026.1817322

• Review

  Published 30 September 2026

  Gene therapy for non-obstructive azoospermia: therapeutic avenues and translational pathway to clinical application

  Man-Xi Jiang · Tao Jing · Huai L. Feng · Yan Zhu

  Frontiers in Genome Editing

  doi 10.3389/fgeed.2026.1921175