Review
Published
A review on advances in chemical compound toxicology prediction
Ahmed Hagag · Nada A. Elsayed · Ibrahim Abdelbaky
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1974935
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Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 110 articles
Original Research
Published
Diffusion-augmented contrastive learning for diabetic retinopathy severity classification
Ali Abidalkareem · Ali K. Ibrahim · Hanqi Zhuang
Frontiers in Artificial Intelligence
doi 10.3389/frai.2026.1932259
Original Research
Published
Development and internal validation of a clinical prediction model for postoperative venous thromboembolism after neurosurgical intervention in patients with traumatic brain injury
Dongping Li · Jianhui Chen · Chunfa Weng · Jianhuang Huang
Frontiers in Neurology
doi 10.3389/fneur.2026.1953953
Original Research
Published
Explainable AI in educational data mining: LightGBM and SHAP for enhancing learner performance prediction
Zakaria Alj · Anas Bouayad
Frontiers in Artificial Intelligence
doi 10.3389/frai.2026.1954446
Review
Published
Canine atopic dermatitis clinical trials: study design and methodological considerations
Michael Klotsman · Sharon K. Sagiv · Wayne H. Anderson · Domenico Santoro
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1878714
Original Research
Published
Development and external validation of an explainable machine learning model for identifying depressive symptoms in middle-aged and older adults with low haemoglobin: a prediction-model study
Qilong Wang · Juan He · Siheng Ma · Jianpeng Zhao · Jingjing Zong · Dongmei Ma · Sha Liu · Lei Zhang · Xin Qi · Dongrong Zhao
Frontiers in Nutrition
doi 10.3389/fnut.2026.1846276
Original Research
Published
Laboratory-derived inflammatory–nutritional exploratory phenogroups and their associations with functional limitation and 30-day same-center all-cause unplanned readmission in patients with heart failure
Yilian Zhang · Xu Zhang · Hongbin Song · Qiyu Hu · Jingzhu Nan
Frontiers in Nutrition
doi 10.3389/fnut.2026.1985953
Original Research
Published
A multi-class fundus disease classification framework based on self-supervised contrastive learning and dual-branch network
Lili Cai · Keke Hou · Zhong Mo · Shining Ding
Frontiers in Medicine
doi 10.3389/fmed.2026.1932626
Original Research
Published
Identification and validation of early vital sign trajectory subphenotypes for risk stratification in sepsis-associated liver injury: a multicenter retrospective cohort study
Weihang Wang · Jing Ma · Bingqing Wang · Jiayang Wang · Zexi Zang · Qiyao Liu · Zhi Gao · Wei Chen · Yuxin Deng · Zhiqing Zhang · Yongfang Jiang
Frontiers in Medicine
doi 10.3389/fmed.2026.1835574
Original Research
Published
Adaptive neuro-fuzzy risk index for safe and interpretable lane-change decisions in Level-3 autonomous driving
Quanda Zu · Shaobo Cai · Jianwei Li
Frontiers in Neurorobotics
doi 10.3389/fnbot.2026.1918469
Original Research
Published
Differential sparse attention framework for accurate ovarian cancer subtype classification using DenseNet121
Muhammad Shoaib Saleem · Javed Rashid · Turke Althobaiti · Faiza Jameel · Khiati Zakaria · Hari Mohan Rai · Anwar Ghani
Frontiers in Digital Health
doi 10.3389/fdgth.2026.1875306
Original Research
Published
Physics-guided multi-channel attention learning for GPR imaging of hidden anomalies in historic masonry
Xiangchi Men · Yannan Zhang · Xianghao Liu · Yaoming Wang
Frontiers in Earth Science
doi 10.3389/feart.2026.1947285
Review
Published
Advances in artificial intelligence-driven MRI research in Alzheimer’s disease
Lihua Deng · Yan Zeng · Peiling Ou · Suyi Zhou · Yu Gou · Cong Huang
Frontiers in Neurology
doi 10.3389/fneur.2026.1943265
Review
Published
Artificial intelligence - driven toxicogenomics for predictive environmental and pharmaceutical safety
Mohammed Monirul Islam · Sibghatullah Muhammad Ali Sangi · Girish Meravanige · Sreeharsha Nagaraja · Muhammad Shahzad Chohan · Md Khalid Anwer · Ashesh Gurung
Frontiers in Genetics
doi 10.3389/fgene.2026.1858338
Original Research
Published
Explainable detection of depression in Arabic tweets: identifying clinically meaningful linguistic markers using SHAP
Erfan Salehi · Maryam Raissi · Amirhossein Rasouli · Wajdi Zaghouani
Frontiers in Artificial Intelligence
doi 10.3389/frai.2026.1917139
Original Research
Published
Concomitant acromioplasty is associated with enhanced structural healing, long-term durability, and functional outcomes in arthroscopic rotator cuff repair: a retrospective propensity score and causal machine-learning analysis
Yucheng Song · Liang Zhao · Can Liu · Yijun Wang
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1840528
Review
Published
Transformers for fMRI analysis: from spatiotemporal modeling to brain foundation models
Xiaomin Yang · Yue Li · Xue Zhang · Bocheng Wang
Frontiers in Neuroinformatics
doi 10.3389/fninf.2026.1869687
Review
Published
A comprehensive review of AI-driven water-quality monitoring and prediction: advances, challenges, and future directions
K. Yukesh Kumar · P. Kumaresan
Frontiers in Water
doi 10.3389/frwa.2026.1946412
Systematic Review
Published
Voice and speech as digital biomarkers of mental health: a scoping review of clinical interpretability, data collection and translational readiness
Ralph Justin Uy · Ibrahim Shaaban · Angel Arnaout
Frontiers in Digital Health
doi 10.3389/fdgth.2026.1964389
Original Research
Published
An interpretable machine learning model for MRI-based morphological classification of lumbar disc herniation using functional biomechanical features
Guanghui Yuan · Can Cui · Yong Xu · Bin Xue
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1856872
Original Research
Published
A data-driven and interpretable hybrid quantum-classical model for male infertility risk assessment
T. Sarath · K. Brindha
Frontiers in Medical Technology
doi 10.3389/fmedt.2026.1853728
Systematic Review
Published
Artificial intelligence, explainable deep learning, and generative models for osteoporosis and bone disease prediction: a systematic review and future research roadmap
M. Raja · Avulapalli Jayaram Reddy
Frontiers in Artificial Intelligence
doi 10.3389/frai.2026.1930437
Original Research
Published
Explainable AI for phishing URL detection: a Bayesian-optimized stacking ensemble framework with SHAP-guided feature learning
Hafiz Aziz Khan · Sonia Akter · Abdur Rahman Lindon · Taslima Akter · Iftekhar Rasul · Mamunur Rahman · Nasrin Akter Tohfa · Iftekhar Hossain
Frontiers in Artificial Intelligence
doi 10.3389/frai.2026.1854934
Review
Published
Artificially intelligent modeling of macromolecular assemblies
Margherita Bini · Valentina Tozzini
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1856649
Original Research
Published
Effects of mapping units on landslide susceptibility assessment: a comparative analysis of slope units and raster cells
Hongqiang Su · Kun Zhao · Bingbing Lei · Erdeng Ai · Jiangao Zhang · Jiangang Chen · Ping Zheng · Luxu Shi
Frontiers in Earth Science
doi 10.3389/feart.2026.1931888
Original Research
Published
Prediction of cognitive impairment in Parkinson’s disease using TabPFN: an integrative analysis of clinical data, longitudinal trajectories, and lipidomics
Zikai Zhou · Jie Liu · Lijuan Wang · Hong Lv · Wencan Jiang · Ling Huang · Guojun Zhang · Ruimin Ma
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1905374
Original Research
Published
Reference ranges and dimensional structure of upper body posture parameters in adults: a cross-sectional study
Lianhua Yin · Chendong Ruan · Xiaojin Zhuang · Lijuan Wu · Xuling Ni · Jing Tao · Lidian Chen
Frontiers in Rehabilitation Sciences
doi 10.3389/fresc.2026.1930857
Original Research
Published
Patient classification using single-cell RNA-sequencing data with deep learning convolutional neural networks
Anastasis Oulas · Nestoras Karathanasis · Theodosios Lampadarios · Raphael Antartis · George M. Spyrou
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1919127
Review
Published
Cancer prevention and interception studies registered in ClinicalTrials.gov: a landscape analysis of trial characteristics and reporting gaps
Martha Fors · Paloma González · Ariel Torres · Lizbeth Silva-Guayasamín · Christian Silva-Sarabia
Frontiers in Epidemiology
doi 10.3389/fepid.2026.1943268
Original Research
Published
Visual cues in MI-BCI induce biases in EEG classification models with deep learning but not with standard machine learning
David Trocellier · Simon Kojima · Bernard N'kaoua · Fabien Lotte
Frontiers in Neuroergonomics
doi 10.3389/fnrgo.2026.1804143
Original Research
Published
A comparative analysis of graph neural networks and classical machine learning for carbapenem-resistance prediction and genomic interpretation in Acinetobacter baumannii
Irfan Sharif Shaik · Morteza Sarmadi
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1885813
Review
Published
Explainable artificial intelligence (XAI) in schizophrenia: enhancing transparency in clinical decision-making
Kshitij Srivastava · Ruby Srivastava
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1898853
Original Research
Published
A unified unsupervised deep learning and stride threat modeling framework for multi-domain cyber-physical security in nuclear digital twins
Mehtab Alam · Akshay Chamoli · Ashraf Ali · Abdullah Alourani
Frontiers in Mechanical Engineering
doi 10.3389/fmech.2026.1926649
Technology and Code
Published
singIST: an R/bioconductor library and quarto dashboard for automated single-cell comparative transcriptomics analysis of disease models and humans
Aitor Moruno-Cuenca · Sergio Picart-Armada · Alexandre Perera-Lluna · Francesc Fernández-Albert
Frontiers in Genetics
doi 10.3389/fgene.2026.1952333
Review
Published
Black boxes and petri dishes: AI models for antimicrobial pharmacokinetics, drug properties, and resistance
Jacob K. McPherson · Surbhi Sharma · Biswajit Mishra · Fadi Shehadeh · Eleftherios Mylonakis
Frontiers in Bacteriology
doi 10.3389/fbrio.2026.1926678
Original Research
Published
Latent multimorbidity classes and antithrombotic medication distributions among patients hospitalized for bleeding after dental surgery: a retrospective study
Juliane Wagner · Johannes Heinrich Spille · Jill Flor · Zeyue Ouyang · Jonas Conrad · Christof Dörfer · Jörg Wiltfang · Hendrik Naujokat
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1917159
Review
Published
AI-driven multi-omics integration in breast cancer: clinical applications, immunotherapy prediction, and translational challenges
Zi-Yao Wang · Na Liu · Min-Bin Chen
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1875788
Original Research
Published
Structurally restricted message-passing within shallow architectures for explainable network-level brain decoding on small cohorts
José Diogo Marques dos Santos · Maria Beatriz Ramos · Luís Paulo Reis · José Paulo Marques dos Santos · Bruno Direito
Frontiers in Behavioral Neuroscience
doi 10.3389/fnbeh.2026.1833995
Original Research
Published
Beyond segmentation accuracy: understanding model reliability and failure modes in ultrasound image analysis
Agathe Bricout · David Hardman · Scott Inglis · Stephen Pye · Carmel M. Moran
Frontiers in Medical Technology
doi 10.3389/fmedt.2026.1918432
Original Research
Published
Predicting female and male participants' contact-exchange decisions from time-segmented multimodal behavioral features in speed dating
Asahi Ogushi · Naoki Azuma · Ryo Ishii · Akihiro Miyata
Frontiers in Computer Science
doi 10.3389/fcomp.2026.1893669
Original Research
Published
An XGBoost–logistic regression hybrid stacking model for breast cancer outcome prediction
Oyetayo Oyebisi · Winnie Chacha · Femi Amoyedo
Frontiers in Applied Mathematics and Statistics
doi 10.3389/fams.2026.1931146
Review
Published
Artificial intelligence in food safety and quality control: applications, challenges, and future perspectives
Aysel İçöz
Frontiers in Food Science and Technology
doi 10.3389/frfst.2026.1931313
Review
Published
The impact of deep learning and omics data in transforming precision therapy for brain cancer
Sana Munquad · Anam Upadhyay · Asim Bikas Das
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1811813
Original Research
Published
Decentralized blockchain governance for explainable causal AI in macroeconomic forecasting
Oumaima Abouzaid · Faouzi Boussedra
Frontiers in Blockchain
doi 10.3389/fbloc.2026.1883639
Original Research
Published
A machine learning framework for interpreting phylogenetic tree patterns in interkingdom horizontal gene transfer
Kevin Aguirre-Carvajal · Cristian R. Munteanu · Vinicio Armijos-Jaramillo
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1891949
Review
Published
Artificial intelligence for sleep-disordered breathing: a taxonomy of methods, data modalities, and clinical applications
Tai Dinh · Daniil Lisik · Philippe Fournier-Viger · Dat Tran · Philip S. Yu · Huynh Van Hong · Ding Zou
Frontiers in Sleep
doi 10.3389/frsle.2026.1927453
Systematic Review
Published
Forecasting sports outcomes through machine learning
Andres Gregori · Ivan Reyes-Pedroza · Ari Yair Barrera-Animas · Julieta Noguez · David Escobar-Castillejos
Frontiers in Computer Science
doi 10.3389/fcomp.2026.1883327
Review
Published
Reproductive performance and predictive models for litter size in sows: a narrative review
Gladness Ntshehi · Khathutshelo Agree Nephawe · Peter Ayodeji Idowu · Takalani Judas Mpofu
Frontiers in Animal Science
doi 10.3389/fanim.2026.1896800