Mini Review
Published
Immunotechnology-based toolbox for care of chronic wounds
Munishwar Nath Gupta · Premlata Ambre
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2026.1979352
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 98 articles
Original Research
Published
Machine learning-based identification of CXCL13 and CXCL10 as key biomarkers in rheumatoid arthritis
Subash M · Sheik Asraf S · Santhanamari M · Nagaraj P · Ayodeji Olalekan Salau · Abdullahi Garba Usman · Mouaz Yousfan
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1925964
Mini Review
Published
Iron homeostasis at the interface of nutrition, infection, and iron supplementation
Özge Mert · Seray Saday · Aybala Temel
Frontiers in Nutrition
doi 10.3389/fnut.2026.1943495
Hypothesis and Theory
Published
Influencing the exposome, patient macroenvironment, tumor microenvironment through-line to improve clinical outcomes
Samuel F. Yanuck · Neil E. Alexis
Frontiers in Oncology
doi 10.3389/fonc.2026.1929067
Original Research
Published
Sprayable phage-cocktail hydrogel promotes diabetic wound healing through macrophage M2 polarization and restoring SP and CGRP signaling axis
Han-Shiang Shiue · Sheng-Jie Shiue · Hsin-Yi Lin · Ming-Shun Wu
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1789996
Review
Published
Obesity-driven inflammation and immune dysregulation in cancer development and progression
Pritika Pandey · Jeb F. Struder · Erika T. Rezeli · Evan M. Paules · Stephen D. Hursting · Michael F. Coleman · Kristin A. Altwegg
Frontiers in Oncology
doi 10.3389/fonc.2026.1947958
Perspective
Published
From macrofungal polysaccharides to precision microbial immunotherapy: reprogramming the tumor microenvironment through immunometabolic and gene-regulatory pathways
Kingsley Excel Dunga · Sylvester Chibueze Izah · Ebinyo Rebecca Aseibai · Matthew Chidozie Ogwu · Vivian Ibienebakabobo Promise · Nsikak Godwin Etim · Irene Nneka Ohanusi
Frontiers in Oncology
doi 10.3389/fonc.2026.1966586
Review
Published
Immunoregulatory roles of the enteric nervous system in esophageal motility control: mechanisms, advances, and therapeutic potential
Ao Wang · Yu-Ting Liao · Hong-Jie Cheng · Nai-Wei Zhang · Yan-Mei Cai · Qiao-Yan Zhang · Hai-Xia Zeng · Bo-Yi Jia
Frontiers in Immunology
doi 10.3389/fimmu.2026.1987626
Review
Published
Functional single-cell omics in gynecological cancers immunotherapy: from heterogeneity dissection to clinical translation
Dong-mei Li · Kai-ge Pei · Bo-wen Yang · Ming-rong Qie · Jin-feng Xu · Lan Zhong · Liang Song
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981010
Review
Published
Extracellular vesicles in colorectal cancer: M2 polarization, bidirectional regulation of CAFs, metastasis, and treatment
Xiaoling Wang · Zhaohua Lai · Hanlu Chen · Mei Yang · Huapei Kang · Fangsheng Wang · Junyun Huang · Yuxin Deng
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1980961
Mini Review
Published
Bioactive small-molecule gas delivery for enhanced bone regeneration: modulation of cellular signaling and remodeling of the regenerative microenvironment
Zhou Zhong · Biao Cao · Xin Duan
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1992564
Original Research
Published
Integrative population genetics and multi-omics reveal IL15RA as a shared pathogenic hub in rheumatoid arthritis-related heart failure
Qishun Geng · Chaoying Wen · Meijia Yang · Yuhan Zhou · Meng Yang · Qishun Geng · Jie Zhao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1956897
Review
Published
Immunometabolic crosstalk between dysfunctional adipose tissue and the brain: implications for postoperative cognitive dysfunction in obesity
Ya-Jiao Hu · Juan Ni · Jin-Xi Zhang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1965479
Review
Published
Macrophage functional plasticity in periodontitis: microenvironmental regulation, disease progression, and therapeutic targeting
Ziqi Gu · Xinyu Li · Gulinur Awuti
Frontiers in Immunology
doi 10.3389/fimmu.2026.1973755
Original Research
Published
The multifaceted role of SsrB in S . Typhi H58 during THP-1 macrophage infection
Marion Fernandez · Soham Deolankar · Moirangthem Kiran Singh · Parisa Zangoui · Linda J. Kenney
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1849419
Review
Published
Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation
Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979311
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Review
Published
Microbial-derived metabolites in cancer: evidence boundaries, immune mechanisms and translational pathways
Xuefeng Shi · Shunjun Wang · Wenhao Ouyang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1947330
Brief Research Report
Published
Distinct spatial immune architectures in tumor and tumor-adjacent tissues of early-stage non-small cell lung cancer
Isabella Polic · Claudio Arrechedera · Jared K. Slone · Amanda Montoya · Emily Bontekoe · Peixin Jiang · Anika Patel · Tatiana V. Karpinets · Xiaogang Wu · Xingzhi Song · Qianyun Luo · Heladio Ibarguen · Auriole Tamegnon · Mei Jiang · Cara Haymaker · Annikka Weissferdt · Ara A. Vaporciyan · Lydia E. Kavraki · Tina Cascone · Ignacio Wistuba · Luisa Maren Solis Soto · John V. Heymach · Jianjun Zhang · Don L. Gibbons · Alexandre Reuben
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981839
Mini Review
Published
A proposed retinal venular immune gate: a mini review of perivascular macrophages and basement-membrane organization
Zhiqing Huang · Zijian Huang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970491
Mini Review
Published
Metabolic stress and macrophage efferocytosis in osteoarthritis: mechanisms and therapeutic implications
HaoYang Wu · DeChao Yuan · RenJian He · ShiWei Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1999085
Original Research
Published
An opsonic peptide promotes radiation-induced macrophage extracellular trap clearance to alleviate inflammation
Yongchan Lee · Gaifeng Ma · Dilara Aylar · Monowar Aziz · Ping Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970645
Original Research
Published
Integrative single-cell and bulk transcriptomic analysis identifies monocyte/macrophage senescence-associated candidate genes in pulmonary arterial hypertension
Xiaojun Chen · Weibin Wu · Yilong Liu · Guili Lian · Qingquan Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938985
Original Research
Published
Tumor-educated macrophages promote ferroptosis inhibition in pancreatic cancer via activating the p62-KEAP1-NRF2 pathway
Shouying Li · Dongxue Qi · Hanyang Yi · Lina Yang · Tonglei Xu · Wenkai Zhou · Weidong Xu · Ziheng Xu · Haodong Tang · Fangliang Xie · Chunfang Zhang · Xuyang Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938077
Original Research
Published
Taxifolin alleviates podocyte injury and macrophage chemotaxis associated with diabetic nephropathy by directly targeting RBP1 identified via multi-omics and machine learning
Zi-Xuan Wang · Wen-Xuan Wang · Qiong-Dan Liang · Ling-Dong Kong
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1933167
Original Research
Published
Quercetin attenuates polystyrene nanoplastic-induced intestinal barrier injury through modulation of macrophage inflammatory responses
Jian Kang · Heng Yang · Yan Wang · Xin Zhang · Chunyang Zhu · Yanhong Zhou · Yanqin Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1973458
Original Research
Published
Evaluation of inflammatory status and macrophage polarization in premature ovarian insufficiency mice induced by chemotherapy
Maoxing Tang · Manzhi Zhao · Yangcheng Yao · Xiqian Zhang · Fenghua Liu
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1798400
Mini Review
Published
Biomarker-guided immunotherapy in osteosarcoma: from immune microenvironment profiling to patient stratification and combination strategies
Qingqing Li
Frontiers in Medicine
doi 10.3389/fmed.2026.1987146
Original Research
Published
Tumor-antigen-specific polyclonal antibodies suppress tumor growth and metastasis in heterogeneous solid tumors
Carine Ciron · Ophélie Dauphouy · Pierre Morice · Pierre-Joseph Royer · Gwenaëlle Evanno · Juliette Rousse · Françoise Shneiker · Bernard Vanhove · Odile Duvaux · Firas Bassissi
Frontiers in Oncology
doi 10.3389/fonc.2026.1947593
Original Research
Published
β-Glucan–mediated macrophage priming enhances macrophage activation and host defense against Mycobacterium tuberculosis infection
Firoz Ahmad · Mohd Khubaib · Rolee Sharma
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1952695
Original Research
Published
Single cell RNA-seq analysis identifies junctional adhesion molecule two positive endothelial cells aggravate osteoarthritis by mediating vascular permeability and macrophage adhesion
Yang Xing · Chengxin Li · Chao Wang · Linli Zheng · Puyi Sheng
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1937741
Review
Published
Gut microbiota-immune-bone axis in osteoporosis: mechanisms and intervention strategies
Minying Huang · Baocheng Xie · Hongyu Liu
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1879472
Review
Published
Nutrition, thyroid function, and tuberculosis: exploring the endocrine–immune axis
Nooneh Khachatourian · Rubina Takhmazian · Vishwanath Venketaraman
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1945832
Original Research
Published
A RIPK2-associated macrophage program links mycobacterial sensing to osteoclastogenesis in bone tuberculosis
Yuyang Zhang · Ziyang Zhang · Dongyang Zhang · Jiulin Tan · Zhaoxin Ma · Qingyang Xiao · Jie Zhang · Qixiu Yu · Zehua Zhang · Yong Tang · Ce Dou · Fei Luo
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1970405
Review
Published
Candida albicans subverts host programmed cell death: a unified framework from pyroptosis to ferroptosis
Limin Fan · Ruining Huang · Kexin Wang · Manting Ni · Xiuyu Nong · Zhenmou Xie · Bo Fu · Lijun Mo · Yinyuan Lan · Qingqing Xu · Wenhan Cao · Xinyue Li · Xueting Liu · Yaohua Xue
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1960578
Original Research
Published
Regulatory role and mechanism of sRNA24 targeting pqsH in Pseudomonas aeruginosa infection immunity
Huanlan Liao · Qianying Liu · Yuyang Liu · Qiwei Li · Yujuan Xiong · Lan Wang · Yang Lu
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1933779
Original Research
Published
Diethyl fumarate exhibits potent activity against differentially culturable Mycobacterium tuberculosis persisters
Amelie J. Herbert · Obolbek Turapov · Fraser MacDonald · Irawaty Djaharuddin · Muhammad Nasrum Massi · Douglas B. Kell · Vadim A. Makarov · Galina V. Mukamolova
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1901638
Original Research
Published
Integrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during Aspergillus fumigatus infection
Jeany Söhnlein · Sascha Schäuble · Juan Prada Salcedo · Zahraa Abboud · Dalia Sheta · Kerstin Hünniger-Ast · Michelle Seif · Hermann Einsele · Thomas Dandekar · Gianni Panagiotou · Andreas Beilhack · Juergen Loeffler
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1922948
Original Research
Published
Natural polysaccharide-engineered POP@ZIF-67 nanoparticles coordinate antibacterial activity, macrophage polarization, and osteogenesis for chronic osteomyelitis therapy
Yunchang Zhao · Guangting Zhu · Mengxue Zhang · Yize Wu · Junwei Su · Jing Hu · Chao Jian · Ying Yuan
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1935416
Original Research
Published
scTIME: single-cell-informed interpretable modeling of immunotherapy-associated immune states in non-small cell lung cancer
Guozhi Chen · Chenqiu You · Hong Gao · Chengjie Xu
Frontiers in Artificial Intelligence
doi 10.3389/frai.2026.1918104
Original Research
Published
Flow cytometric profiling of water buffalo milk EVs: how lactation stage drives phenotypic evolution and macrophage modulation
Barbara Canonico · Mariele Montanari · Ludovica Di Fabrizio · Giulia Franzoni · Giovanna De Matteis · Katia Cappelli · Francesco Grandoni · Maria Carmela Scatà · Daniele Lopez · Samanta Mecocci · Michela Battistelli · Tania Vanzolini · Giovanna Cappelli · Anna Donniacuo · Orlando Paciello · Caterina Ciacci · Stefano Papa · Michele Guescini · Paola Lanuti · Alessandra Martucciello
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1922591
Original Research
Published
LncRNA ZFPM2 silencing alleviates lung epithelial injury by inducing M2 macrophage polarization: possible implication in bronchopulmonary dysplasia
Hanzhou Guan · Huaiqing Yin
Frontiers in Pediatrics
doi 10.3389/fped.2026.1921479
Review
Published
Mesenchymal stromal cells in polytrauma: from immune dysregulation to therapeutic potential
Charles S. Black · Milen Kumar · Renato Miguel Reyes · J. Kent Leach · Mark A. Lee · Håvard Jostein Haugen · Thaqif El Khassawna · Maryam Rahmati · Augustine Mark Saiz
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1892227
Original Research
Published
Integrating transcriptomic analysis to explore biomarkers and therapeutic targets for rheumatoid arthritis: a case-control and systems biology approach
S. Aswini · S. Mohamed Muzammil · N. Raja · S. Asha Devi
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1891543
Original Research
Published
Comparative nanotoxicity of polyethylene, silver, and copper oxide nanoparticles in African catfish (Clarias gariepinus): impacts on antioxidant defense, immunity, and tissue integrity
Mohammed Abdel-Wahab · Yousef A. Bin Jardan · Abdulaziz R. Alqahtani · Mohamed Abbas · Mohamed Hamed
Frontiers in Environmental Science
doi 10.3389/fenvs.2026.1855982
Mini Review
Published
The cochlear macrophage in presbycusis: inflammaging, neuroinflammation, and targets for therapeutic modulation
Reef K. Al-Asad · Judith S. Kempfle
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1930209
Perspective
Published
Beyond the embryo: reframing recurrent implantation failure through immunopriming and endometrial immune dysregulation
Jayesh Amin
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1892030
Review
Published
Cellular remodeling of lipedema affected subcutaneous adipose tissue
Sabrina Gohlke · Francisco Garcia-Carrizo · Robin Upmeyer · Tim J. Schulz
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1893552