Mini Review
Published
Immunotechnology-based toolbox for care of chronic wounds
Munishwar Nath Gupta · Premlata Ambre
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2026.1979352
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 66 articles
Original Research
Published
Machine learning-based identification of CXCL13 and CXCL10 as key biomarkers in rheumatoid arthritis
Subash M · Sheik Asraf S · Santhanamari M · Nagaraj P · Ayodeji Olalekan Salau · Abdullahi Garba Usman · Mouaz Yousfan
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1925964
Hypothesis and Theory
Published
Influencing the exposome, patient macroenvironment, tumor microenvironment through-line to improve clinical outcomes
Samuel F. Yanuck · Neil E. Alexis
Frontiers in Oncology
doi 10.3389/fonc.2026.1929067
Original Research
Published
Sprayable phage-cocktail hydrogel promotes diabetic wound healing through macrophage M2 polarization and restoring SP and CGRP signaling axis
Han-Shiang Shiue · Sheng-Jie Shiue · Hsin-Yi Lin · Ming-Shun Wu
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1789996
Review
Published
Obesity-driven inflammation and immune dysregulation in cancer development and progression
Pritika Pandey · Jeb F. Struder · Erika T. Rezeli · Evan M. Paules · Stephen D. Hursting · Michael F. Coleman · Kristin A. Altwegg
Frontiers in Oncology
doi 10.3389/fonc.2026.1947958
Perspective
Published
From macrofungal polysaccharides to precision microbial immunotherapy: reprogramming the tumor microenvironment through immunometabolic and gene-regulatory pathways
Kingsley Excel Dunga · Sylvester Chibueze Izah · Ebinyo Rebecca Aseibai · Matthew Chidozie Ogwu · Vivian Ibienebakabobo Promise · Nsikak Godwin Etim · Irene Nneka Ohanusi
Frontiers in Oncology
doi 10.3389/fonc.2026.1966586
Review
Published
Immunoregulatory roles of the enteric nervous system in esophageal motility control: mechanisms, advances, and therapeutic potential
Ao Wang · Yu-Ting Liao · Hong-Jie Cheng · Nai-Wei Zhang · Yan-Mei Cai · Qiao-Yan Zhang · Hai-Xia Zeng · Bo-Yi Jia
Frontiers in Immunology
doi 10.3389/fimmu.2026.1987626
Review
Published
Functional single-cell omics in gynecological cancers immunotherapy: from heterogeneity dissection to clinical translation
Dong-mei Li · Kai-ge Pei · Bo-wen Yang · Ming-rong Qie · Jin-feng Xu · Lan Zhong · Liang Song
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981010
Review
Published
Extracellular vesicles in colorectal cancer: M2 polarization, bidirectional regulation of CAFs, metastasis, and treatment
Xiaoling Wang · Zhaohua Lai · Hanlu Chen · Mei Yang · Huapei Kang · Fangsheng Wang · Junyun Huang · Yuxin Deng
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1980961
Original Research
Published
Integrative population genetics and multi-omics reveal IL15RA as a shared pathogenic hub in rheumatoid arthritis-related heart failure
Qishun Geng · Chaoying Wen · Meijia Yang · Yuhan Zhou · Meng Yang · Qishun Geng · Jie Zhao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1956897
Review
Published
Macrophage functional plasticity in periodontitis: microenvironmental regulation, disease progression, and therapeutic targeting
Ziqi Gu · Xinyu Li · Gulinur Awuti
Frontiers in Immunology
doi 10.3389/fimmu.2026.1973755
Original Research
Published
The multifaceted role of SsrB in S . Typhi H58 during THP-1 macrophage infection
Marion Fernandez · Soham Deolankar · Moirangthem Kiran Singh · Parisa Zangoui · Linda J. Kenney
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1849419
Review
Published
Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation
Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979311
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Brief Research Report
Published
Distinct spatial immune architectures in tumor and tumor-adjacent tissues of early-stage non-small cell lung cancer
Isabella Polic · Claudio Arrechedera · Jared K. Slone · Amanda Montoya · Emily Bontekoe · Peixin Jiang · Anika Patel · Tatiana V. Karpinets · Xiaogang Wu · Xingzhi Song · Qianyun Luo · Heladio Ibarguen · Auriole Tamegnon · Mei Jiang · Cara Haymaker · Annikka Weissferdt · Ara A. Vaporciyan · Lydia E. Kavraki · Tina Cascone · Ignacio Wistuba · Luisa Maren Solis Soto · John V. Heymach · Jianjun Zhang · Don L. Gibbons · Alexandre Reuben
Frontiers in Immunology
doi 10.3389/fimmu.2026.1981839
Mini Review
Published
A proposed retinal venular immune gate: a mini review of perivascular macrophages and basement-membrane organization
Zhiqing Huang · Zijian Huang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970491
Mini Review
Published
Metabolic stress and macrophage efferocytosis in osteoarthritis: mechanisms and therapeutic implications
HaoYang Wu · DeChao Yuan · RenJian He · ShiWei Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1999085
Original Research
Published
An opsonic peptide promotes radiation-induced macrophage extracellular trap clearance to alleviate inflammation
Yongchan Lee · Gaifeng Ma · Dilara Aylar · Monowar Aziz · Ping Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970645
Original Research
Published
Integrative single-cell and bulk transcriptomic analysis identifies monocyte/macrophage senescence-associated candidate genes in pulmonary arterial hypertension
Xiaojun Chen · Weibin Wu · Yilong Liu · Guili Lian · Qingquan Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938985
Original Research
Published
Tumor-educated macrophages promote ferroptosis inhibition in pancreatic cancer via activating the p62-KEAP1-NRF2 pathway
Shouying Li · Dongxue Qi · Hanyang Yi · Lina Yang · Tonglei Xu · Wenkai Zhou · Weidong Xu · Ziheng Xu · Haodong Tang · Fangliang Xie · Chunfang Zhang · Xuyang Liang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938077
Original Research
Published
Quercetin attenuates polystyrene nanoplastic-induced intestinal barrier injury through modulation of macrophage inflammatory responses
Jian Kang · Heng Yang · Yan Wang · Xin Zhang · Chunyang Zhu · Yanhong Zhou · Yanqin Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1973458
Original Research
Published
Evaluation of inflammatory status and macrophage polarization in premature ovarian insufficiency mice induced by chemotherapy
Maoxing Tang · Manzhi Zhao · Yangcheng Yao · Xiqian Zhang · Fenghua Liu
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1798400
Original Research
Published
β-Glucan–mediated macrophage priming enhances macrophage activation and host defense against Mycobacterium tuberculosis infection
Firoz Ahmad · Mohd Khubaib · Rolee Sharma
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1952695
Original Research
Published
A RIPK2-associated macrophage program links mycobacterial sensing to osteoclastogenesis in bone tuberculosis
Yuyang Zhang · Ziyang Zhang · Dongyang Zhang · Jiulin Tan · Zhaoxin Ma · Qingyang Xiao · Jie Zhang · Qixiu Yu · Zehua Zhang · Yong Tang · Ce Dou · Fei Luo
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1970405
Review
Published
Candida albicans subverts host programmed cell death: a unified framework from pyroptosis to ferroptosis
Limin Fan · Ruining Huang · Kexin Wang · Manting Ni · Xiuyu Nong · Zhenmou Xie · Bo Fu · Lijun Mo · Yinyuan Lan · Qingqing Xu · Wenhan Cao · Xinyue Li · Xueting Liu · Yaohua Xue
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1960578
Original Research
Published
Diethyl fumarate exhibits potent activity against differentially culturable Mycobacterium tuberculosis persisters
Amelie J. Herbert · Obolbek Turapov · Fraser MacDonald · Irawaty Djaharuddin · Muhammad Nasrum Massi · Douglas B. Kell · Vadim A. Makarov · Galina V. Mukamolova
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1901638
Original Research
Published
Integrative phenotypic and transcriptomic validation of an alveolar-like macrophage model reveals early host–pathogen dynamics during Aspergillus fumigatus infection
Jeany Söhnlein · Sascha Schäuble · Juan Prada Salcedo · Zahraa Abboud · Dalia Sheta · Kerstin Hünniger-Ast · Michelle Seif · Hermann Einsele · Thomas Dandekar · Gianni Panagiotou · Andreas Beilhack · Juergen Loeffler
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1922948
Original Research
Published
Flow cytometric profiling of water buffalo milk EVs: how lactation stage drives phenotypic evolution and macrophage modulation
Barbara Canonico · Mariele Montanari · Ludovica Di Fabrizio · Giulia Franzoni · Giovanna De Matteis · Katia Cappelli · Francesco Grandoni · Maria Carmela Scatà · Daniele Lopez · Samanta Mecocci · Michela Battistelli · Tania Vanzolini · Giovanna Cappelli · Anna Donniacuo · Orlando Paciello · Caterina Ciacci · Stefano Papa · Michele Guescini · Paola Lanuti · Alessandra Martucciello
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1922591
Original Research
Published
LncRNA ZFPM2 silencing alleviates lung epithelial injury by inducing M2 macrophage polarization: possible implication in bronchopulmonary dysplasia
Hanzhou Guan · Huaiqing Yin
Frontiers in Pediatrics
doi 10.3389/fped.2026.1921479
Original Research
Published
Integrating transcriptomic analysis to explore biomarkers and therapeutic targets for rheumatoid arthritis: a case-control and systems biology approach
S. Aswini · S. Mohamed Muzammil · N. Raja · S. Asha Devi
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1891543
Mini Review
Published
The cochlear macrophage in presbycusis: inflammaging, neuroinflammation, and targets for therapeutic modulation
Reef K. Al-Asad · Judith S. Kempfle
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1930209
Perspective
Published
Beyond the embryo: reframing recurrent implantation failure through immunopriming and endometrial immune dysregulation
Jayesh Amin
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1892030
Review
Published
Cellular remodeling of lipedema affected subcutaneous adipose tissue
Sabrina Gohlke · Francisco Garcia-Carrizo · Robin Upmeyer · Tim J. Schulz
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1893552
Original Research
Published
Integrated bulk and single-cell transcriptomic analyses with experimental validation identify PLOD1 as a diagnostic biomarker and TGF-β1-responsive profibrotic mediator in dupuytren’s disease
Xianjie Lin · Mingming Wang · Yutian Lin · Yinshen Zhu · Zhijiang Ye · Haoran Chen
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1924451
Perspective
Published
Neuroimmune phenotypes in brain aneurysms and neurodegenerative diseases
Francis J. Lauzier · David C. Lauzier
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1916561
Review
Published
Neu5Gc and beyond: sialylation at the innate immune and thromboinflammatory interface of xenotransplantation
Jae Young Kim
Frontiers in Transplantation
doi 10.3389/frtra.2026.1968710
Original Research
Published
Integrative bioinformatics screening of a M2 macrophage-associated gene signature for osimertinib resistance
Yajie Huang · Yaozhong Zhang · Jian Shi
Frontiers in Genetics
doi 10.3389/fgene.2026.1928986
Review
Published
Immunosuppressive cell populations as potential drivers of extrinsic immune checkpoint inhibition resistance in clear cell renal cell carcinoma
Usman Humayun Temuri
Oncology Reviews
doi 10.3389/or.2026.1953850
Original Research
Published
Effect of silymarin on Helicobacter pylori growth and adhesion: in vitro and in silico evaluation
Vitor Zorzal Majeski · Milena Lopes Francisco Bittencourt · Pedro Henrique Tregnago · Dalila Nickel Loose · Leonardo Bruno Federico · Rodrigo Rezende Kitagawa · Rita de Cássia Ribeiro Gonçalves
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1890760
Original Research
Published
A single-cell atlas and Shiny-based framework for murine lung injury and remodeling
Qiuming Wang · Jixian Li · Philip J. Moos · Alessandro Venosa
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1886929
Original Research
Published
Integrated AUF-UPLC-MS and fraction-activity correlation to identify COX-2-targeted constituents of Shaoyao Gancao decoction
Liping Li · Jun Chi · Hejia Wan · Yadi Hou · Bingjie Ren · Yixiao Li · Liping Dai
Frontiers in Chemistry
doi 10.3389/fchem.2026.1912431
Review
Published
Non-neoplastic histiocytic proliferations in bone marrow: a case series of uncommon morphologic findings
Melissa Ha · Shafagh Parsazad · Luke T. Dang · Elham Vali Betts · Denis M. Dwyre · Ananya Datta Mitra
Frontiers in Hematology
doi 10.3389/frhem.2026.1939019
Systematic Review
Published
Research hotspots and emerging trends of macrophages in peripheral nerve injury: a bibliometric and visualization analysis
Guohua Jiang · Renkun Huang · Kewen Wang · Yuchang Gui · Yun Tang · Guiyang Jiang · Yijun Liu · Jianwen Xu
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1893849
Original Research
Published
Phytochemical characterization and evaluation of antimicrobial activity of Eugenia sp.: antibacterial, antibiofilm and ampicillin-potentiating activities against resistant Staphylococcus aureus and Staphylococcus epidermidis
Patryne Luana da Silva Dantas · Leticia Bachmann · Alysson Camilla Blaese Gramkov · Thaynara Reichert · Nicole Prada Zibell · Maressa Danielli Dolzan · Matheus Santos Lourenço · Saulo Relison Tintino · Tatiani Karini Rensi Botelho · Diogo Alexandre Siebert · Luciano Vitali · Cícera Datiane de Morais Oliveira-Tintino · Isabel Daufenback Machado · Michele Debiasi Alberton
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1920078
Review
Published
Guanfacine and HCN channels: bridging neuroinflammation and prefrontal cortex function in autism spectrum disorder
Kazuhiko Yamamuro · Takahira Yamauchi · Manabu Makinodan
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1915506
Original Research
Published
Primary cell and tissue cultures of human choroid plexus epithelial cells
Ronja Bihlmaier · Melanie Scharr · Peter H. Neckel · Bernhard Hirt · Andreas F. Mack
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1827493
Original Research
Published
Readiness of the in vitro alveolar macrophage assay: an interlaboratory comparison using 12 blinded particles
Emanoela Thá · Antje Vennemann · Vanessa Marani · Oliver Gräb · Andreas Verlohner · Lan Ma-Hock · Inka Marie Spyridonov · Pamina Weber · Aline Chary · Tommaso Serchi · Robert Landsiedel · Martin Wiemann
Frontiers in Toxicology
doi 10.3389/ftox.2026.1844090
Original Research
Published
Harnessing liposomal delivery to boost polyphenols’ potential in chronic wound therapy
Lisa Myrseth Hemmingsen · Marte Kristensen · Cecilie Thanh Loan Dang · Mari Salamonsen · Elizabeth G. Aarag Fredheim · Nataša Škalko-Basnet
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1839747