Mini Review
Published
SIRT2 in metabolism, aging, and longevity
Menghui Li · Yihuan Dong · Wen Ren · Weixia Dong · Shaoping Ji
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1990670
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 115 articles
Mini Review
Published
Iron homeostasis at the interface of nutrition, infection, and iron supplementation
Özge Mert · Seray Saday · Aybala Temel
Frontiers in Nutrition
doi 10.3389/fnut.2026.1943495
Review
Published
Multidimensional molecular strategies for crop photoperiod adaptation and latitudinal expansion-
Hang Zhao · Shuxin Zhang · Xiaoyu Yin · Nianwei Qiu · Ying Bao
Frontiers in Plant Science
doi 10.3389/fpls.2026.1967465
Original Research
Published
The molecular mechanisms underlying hydrogen peroxide regulating free-living conchocelis maturation of Pyropia haitanensis
Rong He · Wenfei Xian · Yan Xu · Dehua Ji · Chaotian Xie · Wenlei Wang
Frontiers in Plant Science
doi 10.3389/fpls.2026.1979927
Review
Published
Flavonoids in cancer pharmacology: molecular mechanisms, tumor microenvironment regulation, and drug resistance
Zhengyuan Yu · Zhanyi Zhou · Ni Yin · Hongcheng Ge
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1969337
Review
Published
NEDD4-1: from molecular mechanisms to clinical translation in human diseases
Haifen Tian · Yongsheng Huang · Yun Liang · Chengjun Huang · Bingbing Wei · Chang-Neng Liao · Weijie Zhou
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1897001
Mini Review
Published
Molecular mechanisms underpinning cognitive reserve and resilience
Amber Chen · Sreenithi Bhuvaneshwaran · Yash Akkara · Thomas Burke · Robert Perneczky · Magdalena Sastre
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1957901
Correction
Published
Correction: Decoding the mechanisms of acupuncture by neuroimaging: an integrated review from networks to molecules
Shiping Liu · Yan Bai · Jie Liu · Xia Chen · Peizhu Lv · Yulin Wang · Dandan Wang · Shun Wang
Frontiers in Human Neuroscience
doi 10.3389/fnhum.2026.2006254
Review
Published
Gene, microbiome, and anti-aging doping in sport: molecular mechanisms, detection strategies, and implications for sports rehabilitation medicine
Diego Cotella
Frontiers in Sports and Active Living
doi 10.3389/fspor.2026.1984895
Original Research
Published
Berberine-fluconazole synergy against drug-resistant Candida albicans : association with disruption of the Ire1-mediated UPR pathway
Daifan Yue · Dongming Zheng · Zhen Song · Dongmei Li · Yan Li
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1965937
Original Research
Published
Research trends and emerging topics in gut microbiota-derived metabolites and diabetic kidney disease: a multi-database bibliometric analysis (2014–2025)
Xinyu Yang · Xiangning Huang · Yaru Shi · Yunfeng Yu · Rong Yu
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1967850
Mini Review
Published
Mediator complex: the unsung hero of hematopoiesis
Nadezhda A. Kuznetsova · Elena V. Misnik · Ekaterina A. Varlamova · Alvina I. Khamidullina
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1959663
Hypothesis and Theory
Published
Based on the skeletal-muscle dual stem cell chemotaxis and bidirectional differentiation mechanism to reinterpret the “sinew-bone interdependence” theory
Jiahao Dong · Tao Chen
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1869812
Review
Published
Pharmacological regulation of chondrocyte ferroptosis by plant-derived metabolites in osteoarthritis: from molecular mechanisms to targeted nanodelivery
Tianci Guo · Qi Liu · Jida Wang · Keming Ren · Longyao Zhang · Jinzhong Sheng · Aifeng Liu
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1949976
Study Protocol
Published
Cognitive remediation in schizophrenia: efficacy and role of neuroplasticity in “top-down” and “bottom-up” mechanisms—a randomized, double-blind, treatment-as-usual-controlled study protocol
Juan I. Cifuentes · Constanza Orellana · Diego Tello · Cristian Ramírez · Catalina Prieto · Jessica M. Guasti · Rodrigo R. Nieto
Frontiers in Psychiatry
doi 10.3389/fpsyt.2026.1936475
Mini Review
Published
The role of platelet-rich plasma in repeated implantation failure: a review of biological mechanisms and clinical efficacy
Fanourios Makrygiannakis · Thomas Vrekoussis · Maria Marmara · Aikaterini Berdiaki · Antonis Makrigiannakis
Frontiers in Reproductive Health
doi 10.3389/frph.2026.1907558
Review
Published
Molecular mechanisms regulating differential expression of individual miRNAs within polycistronic clusters
Diana Maltseva · Alexander Tonevitsky
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1913118
Systematic Review
Published
Berberine and metabolic dysfunction-associated steatotic liver disease: a global analysis of molecular mechanisms, translational challenges and research frontiers
Fei Yu · Sihan Yin · Jiayu Zhu · Kewei Sun
Frontiers in Nutrition
doi 10.3389/fnut.2026.1969017
Review
Published
Protein glycosylation and glycation in Alzheimer's disease: mechanisms, crosstalk, and therapeutic perspectives
Yuqi Luo · Jingjing Gu
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1925934
Original Research
Published
Identification of microglia-associated hub genes and a CX3CR1/P2RY12 two-gene diagnostic model for cross-subtype epilepsy-associated cortical malformations: integrated transcriptomic analysis with external validation
Hongliang Zeng · Bin Li
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1954412
Original Research
Published
Computational identification of candidate biomarkers and compounds associated with skeletal muscle insulin sensitivity improvement mediated by physical activity: an integrative multi-omics and computational chemistry study
Hong Liu · Zicheng Liang · Jun Tan · Chunyun Yuan
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1885995
Review
Published
Biochemical and molecular mechanisms of probiotic action: current concepts and emerging therapeutic applications
Alexey A. Churin · Lyudmila O. Sokolyanskaya · Anastasia P. Lukina · Olga V. Karnachuk
Frontiers in Nutrition
doi 10.3389/fnut.2026.1964473
Review
Published
The genotoxic burden of toxic metals: bridging molecular mechanisms, biomonitoring, and multidisciplinary interventions
Sameera Reem Imthiaz · Suryapratap Ray · Gracy Anu Francis · Rahul Vashishth
Frontiers in Toxicology
doi 10.3389/ftox.2026.1906308
Original Research
Published
Multi-cohort meta-analysis, single-cell and Mendelian randomization analyses with experimental validation identify RHBDF2 as a shared mediator of ulcerative colitis and blood–brain barrier disruption
Jiongjiong Cheng · Aman Xu
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1970578
Original Research
Published
Time-course profiling of behavioral phenotypes and Ywhah/ERK signaling expression within the vestibular region of the brainstem during motion sickness habituation
Xue Yue · Chenxi Jia · Lihong Zhai · Jie Deng · Dongjun Yang · Zhanguo Jin
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1955920
Original Research
Published
Nicotine and tobacco smoke reshape neuronal signaling networks from a single-nucleus transcriptomic perspective
Jian Jiang · Anfu Hu · Yixiao Jin · Xia Li · Guo-Jun Zhou · Yi Shen · Chengyun Xu · Xing Ji · Ximei Wu · Hong-Juan Wang
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1953804
Original Research
Published
Transcriptomic analysis identifies candidate molecular mechanisms underlying SCF+G-CSF-reduced neuropathology in aged APP/PS1 mice
Afua Addo · Bin Li · Sasidhar Murikinati · Robert Gardner · Li-Ru Zhao
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1705436
Original Research
Published
Integrating Mendelian randomization with single-cell and spatial transcriptomics to investigate gut microbiota-associated genetic signals and molecular characteristics in prostate cancer
Chenjie Qiu · Huilin Zhang · Zongmin Du · Yuan Gao · Liangliang Dai
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1899354
Review
Published
Pathogenesis and molecular mechanisms of steroid-induced femoral head necrosis in children: a narrative review
Fadong Gou · Lu Wu · Xingwen Bao · Wei Wang · Chen Wang · Mingxuan Gao
Frontiers in Pediatrics
doi 10.3389/fped.2026.1897364
Review
Published
Epigenetics in Alzheimer’s disease: from molecular mechanisms to emerging novel biomarkers
Elisabetta D’Aversa · Miriana Grisafi · Salvatore Pernagallo · Francesca Salvatori · Ajay V. Singh · Alessia Nucciarone · Veronica Tisato · Donato Gemmati
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1959361
Review
Published
Dexmedetomidine as a potential neuroprotective agent against Alzheimer’s disease: molecular mechanisms and therapeutic perspectives
Jun Kang · Yongbo Duan · Jiaxuan Bi · Jiangping Liu · Wenjun Yan
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1952923
Original Research
Published
Molecular mechanism of dynamic regulation of the proNGF/NGF ratio in controlling hair follicle cycle transition in liaoning cashmere goats
Bing Luo · Di Han · Meng Sun · Jianwei Wei · Mingqian Li · Shuai Chang · Zhiguo Quan · Ying Wang · Chunqiang Wang · Wei Ma
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1940416
Original Research
Published
Methylglyoxal hampers the angiogenic capacity of human retinal endothelial cells modifying cell transcriptome with the contribution of NRSF/REST
Marianna Aprile · Cecilia Nigro · Caterina Perfetto · Alessia Leone · Simona Cataldi · Antonella Nicolò · Mariagiovanna Tramontano · Antonella Desiderio · Francesco Beguinot · Valerio Costa · Claudia Miele · Alfredo Ciccodicola
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1762167
Review
Published
Artificially intelligent modeling of macromolecular assemblies
Margherita Bini · Valentina Tozzini
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1856649
Original Research
Published
Mechanistic study on components of Angelica Pubescens-Taxillus Chinensis in improving compression-induced intervertebral disc degeneration via piezo1/NF-κB signaling axis
Fei Yang · Chaoqun Feng · Guangye Li · Junwen Deng · Yunchuan Gou · Bingyi Yang · Ying Zhang · Xin Zhou · Chuan Leng · Maoyin Luo · Rigao Chen · Xiaohong Fan
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1935597
Review
Published
Cellular remodeling of lipedema affected subcutaneous adipose tissue
Sabrina Gohlke · Francisco Garcia-Carrizo · Robin Upmeyer · Tim J. Schulz
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1893552
Review
Published
Gut microbiota–cancer crosstalk: emerging molecular targets for personalized cancer treatment- a comprehensive review
Pooja Negi · Arpita Upreti · Preeti Budhlakoti · Amit Kumar Sen · Mitali Danu · Sumit Tewari · Nirmal Joshi · Deepak Chandra Joshi
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1924197
Review
Published
Comprehensive insights into molecular techniques and applications for genetic modification and targeted mutagenesis in zebrafish
Nahida Quyoom · Gowhar Iqbal · Lukram Sushil Singh · Shafiya Mushtaq · Showkat Ahmad Dar
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1820777
Original Research
Published
Intact spatial learning in Fmr1 –/ y, Syngap1 +/–, and Grin2b +/– rat models of neurodevelopmental disorders
Anuj Vadher · Adrian J. Duszkiewicz · Emma R. Wood · Paul A. Dudchenko
Frontiers in Behavioral Neuroscience
doi 10.3389/fnbeh.2026.1929983
Original Research
Published
TrkC-dependent regulation of dendritic branching shapes dendritic bundle architecture in the rat granular retrosplenial cortex
Toshio Miyashita
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1925955
Review
Published
Garlic-derived bioactive components in neuropathic pain: molecular mechanisms and therapeutic promise
Asif Ali · Sorimuthu Revathi · Koilmani Emmanuvel Rajan · Chin Kun Wang · Subramanian Thangaleela
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1886063
Original Research
Published
The impact of zeaxanthin and lycopene on fatty acid beta-oxidation in isolated peroxisomes from frozen livers of obese rats
Lina Baz · Mona Al-Thepyani
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1906904
Original Research
Published
Combined exposure to emerging Fusarium mycotoxins produces concentration-dependent synergistic toxicity in Jurkat T cells
Chanamon Maleeratana · Phattarawadee Wattanasuntorn · Saranya Poapolathep · Imourana Alassane-Kpembi · Johanna Fink-Gremmels · Isabelle P. Oswald · Amnart Poapolathep
Frontiers in Toxicology
doi 10.3389/ftox.2026.1924250
Review
Published
Breaching the Weismann barrier – a role of vitellogenin yolk proteins in nematode non-Mendelian inheritance
Shiela Pearl Quiobe · Ralf J. Sommer
Frontiers in Ecology and Evolution
doi 10.3389/fevo.2026.1956995
Brief Research Report
Published
SST interneuron maturation extends beyond the second postnatal week and is driven by coordinated transcriptional and functional remodeling
Ourania Christodoulou · Konstantinos Diskos · Angeliki Velli · Panagiotis Moulos · Kyriaki Sidiropoulou · Myrto Denaxa
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1892850
Original Research
Published
Median nerve electrical stimulation promotes myelin regeneration through regulating miR-1-3p/BDNF/TrkB-MAPK pathway in a transient cerebral ischemia rat model
Rui Li · Jingyi Lu · Chengcai Zhang · Xiaowei Zhang · Meiqi Wang · Ping Zhang · Kunli Yang · Hongmei Fang · Ying Gao · Kistina Mohamed · Che Ismail Che Noh · Yi Li · Kai Ling Chin
Frontiers in Behavioral Neuroscience
doi 10.3389/fnbeh.2026.1820913
Review
Published
Beyond tobacco: understanding the growing burden of lung adenocarcinoma in women
Michael Christian A. Virata · Rizal Michael Ramos Abello · Edroico Mari Beltran Brillante · Jasmine Soco Interior · Patrick Reyes Relacion · Ryan Gabriel C. Molen · Eryll Paolo M. Alea · John Cedric P. Mojica
Oncology Reviews
doi 10.3389/or.2026.1813124
Review
Published
Maternal high-fat diet and risk of cardiovascular disease in offspring: a review of mechanisms, controversies, and interventions
Heyu Meng · Jianjun Ruan · Qing Wang · Fanbo Meng
Experimental Biology and Medicine
doi 10.3389/ebm.2026.11199