Articles

Showing 106 articles

• Original Research

  Published 9 October 2026

  Sex-dependent transcriptional and imaging responses to metformin in young-adult mice with SuHx-induced pulmonary arterial hypertension

  Irene Fernández-Folgueral · María Jesús Sánchez-Guisado · Irati Aiestaran-Zelaia · Marta Beraza · Aitor Zubillaga-Unsain · Claudia Miranda-Pérez de Alejo · Amanda Marrero-Pérez de Alejo · Kinsey Mae Thorpe · Angela Frimpong · Rui Adão · Ian J. Holt · Jesús Ruiz-Cabello

  Frontiers in Cardiovascular Medicine

  doi 10.3389/fcvm.2026.1947678

• Original Research

  Published 8 October 2026

  Immediate anxiety-reducing effects of multisensory virtual reality reminiscence therapy in older adults with a wide range of cognitive functions: a pilot study using electrophysiological measures

  Keita Ueno · Kazuyuki Niki · Hiroyuki Tanaka · Takeshi Okuda · Daisuke Iwai · Kosuke Sato · Yasuo Naito · Toshinori Ito · Ryouhei Ishii

  Frontiers in Aging Neuroscience

  doi 10.3389/fnagi.2026.1958403

• Original Research

  Published 8 October 2026

  Open wavefront ablation terminates rotor-driven atrial fibrillation

  Arthur S. Bezerra · Robin Van Den Abeele · Bram Van Landeghem · Bjorn Verstraeten · Sebastiaan Lootens · Viktor Van Nieuwenhuize · Sander Hendrickx · Vincent F. M. Segers · Mattias Duytschaever · Nele Vandersickel

  Frontiers in Network Physiology

  doi 10.3389/fnetp.2026.1940428

• Systematic Review

  Published 8 October 2026

  Cross-model metabolomic signatures of dietary anti-inflammatory (poly) phenols in nutraceutical development: a systematic review

  Adesoji Fayomi · Emmanuel Adom · Alberta N. A. Aryee

  Frontiers in Molecular Biosciences

  doi 10.3389/fmolb.2026.1824027

• Original Research

  Published 8 October 2026

  Amomum tsao-ko volatile oil alleviates renal fibrosis in 5/6 nephrectomy rats through TGF- β 1/SMAD3 and PI3K/AKT signaling pathways

  Huanyue Cui · Meiru Shi · Qing Xu · Shangwen Zhou · Xin Li · Hangyu Wang · Dahong Yao · Ke Zhang · Pinghua Sun · Jinhui Wang

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1819932

• Review

  Published 8 October 2026

  Therapeutic potential of Boswellia -derived compounds in skin conditions

  Eman A. Alturki · Caroline S. Weckerle · Caroline Maake · Raha Orfali · Michael Heinrich

  Frontiers in Pharmacology

  doi 10.3389/fphar.2026.1966705

• Mini Review

  Published 8 October 2026

  Plant essential oils as a novel therapeutic strategy for depression and anxiety: emerging evidence and mechanisms

  Jiahui Hong · Liting He · Jingquan Chen · Hongxuan Cai · Weiyi Cheng · Ji-gang Piao · Jingjing Zhu

  Frontiers in Psychiatry

  doi 10.3389/fpsyt.2026.1920527

• Original Research

  Published 7 October 2026

  Family physicians’ knowledge, attitudes, and practices regarding complementary and alternative medicine in Saudi Arabia: an exploratory cross-sectional study

  Safaa M. Alsanosi · Asim M. Alshanberi · Aljawharah Alqathama · Majd Almech · Husna Irfan Thalib · Bandar M. Abuageelah · Ameena Manzoor · Ruwaydah Hamoud M. Alruways · Yosra Alhindi · Maram H. Alshareef

  Frontiers in Health Services

  doi 10.3389/frhs.2026.1837145

• Original Research

  Published 7 October 2026

  Species-specific IgE recognition of cockroach allergens in human–dog dyads sharing the same household

  Mey-Fann Lee · Jane Lu Hsu · Ching-Chun Lin · Yu-Wen Chu · Nancy M. Wang

  Frontiers in Allergy

  doi 10.3389/falgy.2026.1932833

• Original Research

  Published 7 October 2026

  EPA and DHA engage NRF2 to orchestrate a β-cell resilience circuit suppressing senescence remodeling and sustaining molecular fitness during glucolipotoxic stress

  Chaofeng Xing · Fanghong Li · Yan Zou · Cheng Song · Dan Luo · Jian Ruan · Minyi Tang · Qihua Xu · Yunping Mu · Jie Shen · Allan Zijian Zhao

  Frontiers in Physiology

  doi 10.3389/fphys.2026.1948763

• Hypothesis and Theory

  Published 7 October 2026

  The developmental dopamine trajectory hypothesis of ADHD across the lifespan

  Raly James Perez Custodio · Stephan Getzmann · Edmund Wascher · Michael C. Pan · Florence Ingred Samante · Fred Lawrence Samante · Bung-Nyun Kim · Hee Jin Kim · Eugene C. Yi · Jae Hoon Cheong

  Frontiers in Psychiatry

  doi 10.3389/fpsyt.2026.1944446

• Review

  Published 5 October 2026

  Advances and applications of wearable electrochemical sensors in personalised medicine and precision agriculture: a systematic review

  Vaibhav Sharma · Anuj Sharma · Raj Shukla · Mahipal Singh Sankhla · Garima Awasthi · Amanpreet Singh · Manpreet Kaur · Diksha Pathania · Sheifali Gupta · Kumud Kant Awasthi · Harsh Sable

  Frontiers in Sensors

  doi 10.3389/fsens.2026.1951973

• Original Research

  Published 5 October 2026

  Stability and dermatological safety assessment of Cryptocarya alba (Peumo) and Laureliopsis philippiana (Tepa) essential oil-carrying dry shampoo formulations for dermal use in dogs

  Martín Varas · Martina Jacobs · Nicole Rojas · Paola Ramos · Flavia Bruna · Gabriela Valenzuela-Barra · Olosmira Correa · Antonia Díaz-Parra · Manuel Ahumada · Gabriela Maturana · Irene Martínez · Francisco Abusleme · Belén Rivera · María Olga Bargsted · Daniela Siel · Jessica Bravo

  Frontiers in Veterinary Science

  doi 10.3389/fvets.2026.1918882

• Original Research

  Published 5 October 2026

  Polystyrene nanoplastics impair mitochondrial function, quality control, and ER–mitochondria crosstalk in HeLa cells

  Giuseppe Petito · Maria Teresa Gentile · Arianna Cuomo · Angelo Fusco · Sara Falvo · Maria della Valle · Gianluca D’Abrosca · Carla Isernia · Roberto Fattorusso · Maria Emanuela Errico · Antonia Lanni · Gaetano Malgieri · Rosalba Senese

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1907794

• Original Research

  Published 30 September 2026

  1 H NMR-based profiling and candidate prioritization of interaction-associated metabolites from fungal co-cultures

  Mustapha N. Abubakar · Vitor S. Mazucato · Paulo C. Vieira

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1879578

• Original Research

  Published 30 September 2026

  Antibiotic prescribing appropriateness among critically ill patients at a single tertiary care center in the United Arab Emirates: a retrospective cohort study

  Inas Kassis · Mosab Al Balas · Sheilla Hilal Hamed Rashid · Shabaz Mohiuddin Gulam · Jisha Myalil Lucca · Kimberly Caye McKeirnan · Vineetha Menon

  Frontiers in Health Services

  doi 10.3389/frhs.2026.1900610

• Original Research

  Published 29 September 2026

  MambaGLA-NPC: a 3D framework integrating CNN and state space models for robust multi-center nasopharyngeal carcinoma segmentation

  Wei Jin · Xiaobo Chen · Weifeng Jin · Hai Liao · Li Yu

  Frontiers in Genome Editing

  doi 10.3389/fgeed.2026.1954329

• Hypothesis and Theory

  Published 28 September 2026

  A pragmatic workflow for integrating large language models into toxicological risk assessment

  Arianna Bassan · Alexander Amberg · Maria Letizia Barreca · Paul M. Bradley · Frank Bringezu · Joyce De Paula Souza · Corinne Guicheney · Elena Lo Piparo · Simona Kovarich · Andrey Massarsky · Georgia Maundrill · Lance Molnar · Cristina Parenti · Patricia Parris · Manuela Pavan · John F. Reichard · Ron Steigerwalt · Olga Tcheremenskaia · Kenneth Unice · Christopher J. Waine · Geraldine Whelan · Angela White · Glenn J. Myatt

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1877128

• Original Research

  Published 25 September 2026

  Quality by design driven development of a Monteverdia ilicifolia herbal medicine: from plant to granules

  Alberto Araujo de Caux · José Cláudio Klier Monteiro Filho · Ruan Barbosa da Silva e Medeiros · Marili Villa Nova Rodrigues · Marcos Nopper Alves · Marcus Bruno Soares Forte · Maria Isabel Rodrigues · Rodney Alexandre Ferreira Rodrigues

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1887810

• Original Research

  Published 23 September 2026

  Effect of silymarin on Helicobacter pylori growth and adhesion: in vitro and in silico evaluation

  Vitor Zorzal Majeski · Milena Lopes Francisco Bittencourt · Pedro Henrique Tregnago · Dalila Nickel Loose · Leonardo Bruno Federico · Rodrigo Rezende Kitagawa · Rita de Cássia Ribeiro Gonçalves

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1890760

• Original Research

  Published 23 September 2026

  Preconception care knowledge, attitudes, and practices among women attending a private women's hospital in Riyadh, Saudi Arabia: a cross-sectional study

  Rola E. Alhabbash · Aiman Y. Alwadi · Sadeq B. Abu-Dawas · Abdullah Binsaeedu · Beenish Maqsud · Sally Yahya · Fouad F. Jabri · Mohammad H. Rajab · Noara K. Alhusseini

  Frontiers in Global Women's Health

  doi 10.3389/fgwh.2026.1947977

• Original Research

  Published 18 September 2026

  Approval lag and loss for biologic-device combination products in Japan and the United States

  Makiko Mochizuki · Hideki Maeda

  Frontiers in Medical Technology

  doi 10.3389/fmedt.2026.1924169

• Original Research

  Published 18 September 2026

  Cross-species gene expression analysis identifies a type I interferon-associated transcriptional signature in Tregs from atopic dermatitis

  Naoya Kase · Hina Nakamura · Chizuru Nakakomi · Manami Shimakata · Mai Banno · Ryotaro Kanari · Yohsuke Harada

  Journal of Cutaneous Immunology and Allergy

  doi 10.3389/jcia.2026.17310

• Original Research

  Published 16 September 2026

  GCMS profiling and larvicidal potentials of the extracts of Terminalia catappa leaf, Eucalyptus citriodora seed and stem against malarial, dengue and filarial vector mosquitoes (Diptera: Culicidae)

  Eze Elijah Ajaegbu · Juliet Onyinye Nwigwe · Chidinma Claribel Chikezie · Nkeiru Catherine Enyi

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1934443

• Review

  Published 16 September 2026

  Engineering the oxidative myocardium: ROS-responsive biomaterials for precision cardiovascular delivery in ischemia-reperfusion injury and post-infarction remodeling

  Hossein Omidian · Kwadwo A. Mfoafo · Luigi X. Cubeddu

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1929035

• Review

  Published 16 September 2026

  Copper nanoparticles and their future in drug delivery and anticancer therapy

  Keykavous Parang · Rajesh Vadlapatla · Cassia Charles · Kimberly Tang · Trang Nguyen · Amir Nasrolahi Shirazi · Ajoy Koomer

  Frontiers in Nanotechnology

  doi 10.3389/fnano.2026.1906191

• Original Research

  Published 16 September 2026

  Identification of natural TLR4 modulators through network pharmacology and molecular modeling in SARS-CoV-2 Acinetobacter baumannii co-infection

  Mebarka Ouassaf · Shafi Ullah Khan · Kannan R. R. Rengasamy · Nada S. Alhaggass · Bader Y. Alhatlani

  Frontiers in Chemistry

  doi 10.3389/fchem.2026.1916568

• Original Research

  Published 15 September 2026

  Artificial intelligence modeling of small molecule pharmaceutical solubility in supercritical fluid and comparative analysis under temperature and pressure variations

  Haolin Wu · Hadil Faris Alotaibi · Ahmed Salah Fahem · Saeed Shirazian

  Frontiers in Chemistry

  doi 10.3389/fchem.2026.1947884

• Original Research

  Published 15 September 2026

  ALDH1/2 deficiency modulates dieldrin-induced dopaminergic neurodegeneration and reactive glial morphometry in male mice

  Omar A. Yanouri · Adam J. Schuller · Savannah M. Rocha · Aidan M. Briggs · Paul A. Martinez · Elizabeth Fernandez · Randy Strong · Xueshu Li · Hans-Joachim Lehmler · Jonathan A. Doorn · Ronald B. Tjalkens

  Frontiers in Toxicology

  doi 10.3389/ftox.2026.1888799

• Original Research

  Published 14 September 2026

  Comprehensive phytochemical study of Galianthe thalictroides: isolation of three new compounds, structural revision of β-carbolines, and evaluation of cytotoxic and anti-wnt activities

  Patrícia de Oliveira Figueiredo · Olivier August Kirchhoffer · Laurence Marcourt · Luis Quiros-Guerrero · Alexey Koval · Wilson Hino Kato Junior · Nídia Cristiane Yoshida · Fernanda Rodrigues Garcez · Walmir Silva Garcez · Vladimir L. Katanaev · Jean-Luc Wolfender · Emerson Ferreira Queiroz

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1840056

• Original Research

  Published 14 September 2026

  Exploratory scaffold hopping strategies led to identification of novel histamine H 3 and H 4 receptor ligands

  Flávia B. Lopes · Denise Mönnich · Gustavo A. B. Fernandes · Steffen Pockes · João Paulo S. Fernandes

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1944403

• Original Research

  Published 14 September 2026

  Fungal contamination, mycotoxins, histamine, and allergen-related immunoreactivity in edible insects and insect-fortified complementary foods

  Maryam Imbumi · Sheila Okoth · Kris Audenaert · Hans De Steur · Xavier Gellynck · Chrysantus Mbi Tanga · Sarah De Saeger · Judith Kimiywe · Katleen Raes

  Frontiers in Fungal Biology

  doi 10.3389/ffunb.2026.1798430

• Original Research

  Published 11 September 2026

  Bioinspired rhyolite particles as a functional material for lipid regulation in diet-induced obesity

  Ahmad Bikharudin · Masahiro Okada · Satoshi Wakai · Ping-Chin Sung · Akihisa Otaka · Nutan Bhingaradiya · YuYang Jiao · Takuya Matsumoto

  Frontiers in Food Science and Technology

  doi 10.3389/frfst.2026.1964244

• Review

  Published 9 September 2026

  Nipah virus vaccine development: current platforms, preclinical evidence, and clinical translation

  Shrabonti Chatterjee · Joydeep Mahata · Athika Firdous · Moh. Royhan Afnani · Rangga Adhi Prastika · Muhammad 'Ahdi Kurniawan · Volta Kellik Setiawan · Farah Arini Subekti · Fara Disa Durry · Sukma Sahadewa · Aswin Rafif Khairullah · Yudhi Nugraha · Tegar Achsendo Yuniarta · Timotius Ivan Hariyanto · Abhishek Singh · Vikash Jakhmola · Nitin Sharma · Abdugani Abdurasulov · Maksim Rebezov · Arif Nur Muhammad Ansori · Rollando Rollando · Arli Aditya Parikesit

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1906594

• Correction

  Published 9 September 2026

  Correction: Network-based integrative analysis of multi-level regulatory mechanisms associated with glyphosate exposure

  Claudia Consuegra-Mayor · Barbara Arroyo-Salgado · Jesus Olivero-Verbel

  Frontiers in Bioinformatics

  doi 10.3389/fbinf.2026.1979796

• Original Research

  Published 9 September 2026

  Charge modulation of peptide/nucleic acid complexes: an anionic additive enhances gene silencing and CRISPR/Cas9 editing by promoting intracellular nucleic acid release

  Abdulelah Alhazza · Sorour Khayyatnejad Shoushtari · Hasan Uludag · Keykavous Parang · Hamidreza Montazeri Aliabadi

  Frontiers in Nanotechnology

  doi 10.3389/fnano.2026.1925723

• General Commentary

  Published 7 September 2026

  Commentary: “Bridging innovation and equity: the evolving landscape of CAR T-cell therapy access in Brazil” The Uruguayan pediatric experience

  Maria Ines Pereira · Marcela Barrios · Lucia D’ Andrea · Manuel Ibarra · Susana Rives · Luis Castillo

  Frontiers in Hematology

  doi 10.3389/frhem.2026.1891877

• Original Research

  Published 3 September 2026

  Antifungal and antibiofilm activity of crude hydroalcoholic extract and fractions of Myrcia neoobscura leaves against a clinical isolate of Candida krusei

  Leticia Bachmann · Eduarda Rensi Botelho · Patrícia Helena Arrabal · Pâmela Elise Munzlinger · Patryne Luana da Silva Dantas · Larissa Mascarenhas Krepsky · Lucas Ferriolli Mariotto · Michele Debiasi Alberton · Tatiani Karini Rensi Botelho

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1914843

• Original Research

  Published 3 September 2026

  Formulation and in vitro prospectus of probiotics, beetroot, and vitamin B12 encapsulated in alginate beads

  Tanhid Mansuri · Rajesh Hadia · Annu · Samaresh Pal Roy · Aayush Panchal

  Frontiers in Food Science and Technology

  doi 10.3389/frfst.2026.1850082

• Review

  Published 3 September 2026

  Machine learning-enabled formulation development of implantable drug delivery systems for precision medicine: from ocular and cochlear implants to personalized therapeutics

  Rohini Ganvenwaer · Shaktiprasad Pradhan · Kranti Jadhav · Kuldeep Vinchurkar · Rohit Ramesh Doke

  Frontiers in Biomaterials Science

  doi 10.3389/fbiom.2026.1927008

• Original Research

  Published 3 September 2026

  A systems microbiology framework for reproducible multi-dataset omics integration with application to long COVID

  Brigitta Varga · Marlet Martinez-Archundia · Linette E. M. Willemsen · Johan Garssen · Alejandro Lopez-Rincon

  Frontiers in Systems Biology

  doi 10.3389/fsysb.2026.1873899

• Review

  Published 28 August 2026

  Oral absorption of high molecular weight polyethylene glycols: mechanistic, safety and regulatory insights

  Chiara G. M. Gennari · Sara Azari · Antonella Casiraghi · Umberto M. Musazzi

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2026.1851318

• Original Research

  Published 28 August 2026

  Genetic modulation of oxycodone self-administration trajectories: from initiation to escalating burst patterns

  Caleb I. Hodges · Eamonn P. Duffy · Jonathan O. Ward · Luanne H. Hale · Cove C. Andrews · Laura M. Saba · Marissa A. Ehringer · Ryan K. Bachtell

  Frontiers in Behavioral Neuroscience

  doi 10.3389/fnbeh.2026.1913370

• Original Research

  Published 25 August 2026

  Molecular abnormalities scale across three models of cerebral injury

  Volha Liaudanskaya · Matthew J. Robson · Nicole L. Vike · Sumra Bari · Christopher J. O’Connell · Orlando S. Hoilett · David L. Kaplan · Thomas M. Talavage · Eric A. Nauman · Semyon Slobounov · Hans C. Breiter

  Frontiers in Molecular Neuroscience

  doi 10.3389/fnmol.2026.1844343

• Review

  Published 25 August 2026

  Translational advances in diabetic nephropathy management: integrating nanoformulation-based drug delivery systems

  Mohd Danish Ansari · Ashish Vishwakarma · Md Quamuddin · Mansi Aggarwal · Hashim Khan · Muhammad Fauzi Abd Jalil · Syed Mahmood · Adil Farooq Wali · Sirajunisa Talath · Mohamed El-Tanani

  Frontiers in Medical Technology

  doi 10.3389/fmedt.2026.1951734

• Review

  Published 24 August 2026

  Organelle-specific crosstalk between calcium and redox signaling in pancreatic β-cells in physiology and type 2 diabetes

  Lucas Rafael Pereira Camara · Eloisa Aparecida Vilas-Boas

  Frontiers in Network Physiology

  doi 10.3389/fnetp.2026.1864821

• Original Research

  Published 24 August 2026

  Paraventricular thalamic neurons respond to vagus nerve activation and modulate anxious behavior

  Ziyan Xie · Musashi Yamakawa · Tasuku Kayama · Takuya Sasaki · Nahoko Kuga

  Frontiers in Neural Circuits

  doi 10.3389/fncir.2026.1865790

• Original Research

  Published 21 August 2026

  Quality monitoring in telestroke networks: real-world insights from survey response data and literature review

  Ayush Agarwal · Christine Tunkl · Alexandra Krauss · Emily R. Ramage · Mirjam R. Heldner · Stefan T. Gerner · Teresa Ullberg · Leonardo A. Carbonera · Jatinder S. Minhas · Aristeidis Katsanos · Matias J. Alet · Abdul H. K. Y. Khan · Faddi Saleh Valez · Tamer Roushdy · Linxin Li · Bogdan Ciopleias · Zhe Kang Law · Radhika Lotlikar · Susanna M. Zuurbier · Maria G. Mosconi · Shirsho Shreyan · Shakti Shrestha · Gisele S. Silva · Annemarei Ranta

  Frontiers in Stroke

  doi 10.3389/fstro.2026.1879025