Review
Published
A review on advances in chemical compound toxicology prediction
Ahmed Hagag · Nada A. Elsayed · Ibrahim Abdelbaky
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1974935
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 275 articles
Original Research
Published
Biogenic fabrication of zinc oxide nanoparticles for enhanced germination and early seedling establishment of rice under salinity stress
Jennifer Flora · Saiyyeda Firdous
Frontiers in Nanotechnology
doi 10.3389/fnano.2026.1944557
Review
Published
The liver–gut–bone axis in hepatic osteodystrophy: mechanisms, clinical evidence and therapeutic perspectives
Liangping Zhang · Ting Jiang · Rongqi Cao · Linqiu Han · Ligang Ni
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1935323
Review
Published
Beyond single-element toxicity: chromium-salinity interactions, food-chain transfer and mitigation in sugarcane agroecosystems
Gowtham Sornam · Sugumaran Melkumaramangalam Palani · Parameswari Ettiyagounder · Kalaiselvi Thangavel · Saravanan Naaganoor Ananthan · Elayarajan Maharajan · Selva Kumar Manikkam · Sassikumar Datchinamoorthy · Sinduja Murugaiyan · Priyatharsini Sengottaiyan
Frontiers in Sustainable Food Systems
doi 10.3389/fsufs.2026.1942892
Original Research
Published
Exploring the protective mechanism of Huangqishengmaiyin against anthracycline-induced cardiotoxicity in breast cancer with concomitant gut microbiota modulation
Yixuan Wang · Yeying Jin · Jiali Han · Mingjia Ding · Haoqing Hou · Miaoyu Mei · Rui Yang
Frontiers in Cardiovascular Medicine
doi 10.3389/fcvm.2026.1818551
Review
Published
From environmental occurrence to human exposure: multisystem toxicity, immune-relevant mechanisms, and gaps in health-risk assessment of liquid crystal monomers
Hongchi Zhang · Jingle Qiu · Zhenyu Lu · Xiangbin Zheng · Xia Huo · Xijin Xu
Frontiers in Public Health
doi 10.3389/fpubh.2026.1977975
Original Research
Published
Low-affinity anti-HER2-CAR T cells efficiently eradicate HER2 + and HER2 low cancer cells with reduced toxicity on healthy tissue
Leonard Knoedler · Konstantin Herfeld · Julian N. Scherer · Kaiji Fan · Dhyani Shah · Sascha Goettert · Luisa Becker · Iria Lloshi · Suqi Li · Dennis C. Harrer · Matthias A. Fante · Tobias Wertheimer · Roland Schelker · Severin Guetter · Misbah Tariq · Omer Khalid · Alexander Scheiter · Wolfgang Herr · Christian Schmidl · Moritz Jesinghaus · Markus Tschurtschenthaler · Hendrik Poeck · Markus Perl
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1895507
Mini Review
Published
Arsenic trioxide-induced cardiotoxicity: insights into the oxidative stress-inflammation positive feedback loop, translational biomarkers and targeted cardioprotective strategies— a narrative review
Haiyan Wu · Jian Lv · Xiaoyang Hu
Frontiers in Oncology
doi 10.3389/fonc.2026.1954263
Clinical Trial
Published
Preliminary evaluation of ProSpare ® , a rectal obturator for prostate bed radiotherapy within the randomised multicentre POPS trial (NCT02978014)
Sarah Stewart · Karen Thomas · Jenni Parmar · Alison Claire Tree · Chris Parker · Helen McNair · Sophie Alexander · Julia Henderson · James Talbot · Christopher Scrase · Chee Goh · Reena Davda · Emma Gray · Peter Hoskin · Sarah Needleman · Jenny Nobes · Kamalram Thippu Jayaprakash · Yvonne Rimmer · Ranachandran Venkitaraman · Anna Wilkins · Vincent Khoo · Julia Murray · David Paul Dearnaley
Frontiers in Oncology
doi 10.3389/fonc.2026.1758462
Perspective
Published
Revisiting proton therapy for adenoid cystic carcinoma: a case worth making
Astha Rohit · Adam Holtzman · James Bates · Scott Lester · Roi Dagan · Barbara Vischioni · Ester Orlandi · Maria Bonora · Amy Tien Yee Chang · Rohan Deraniyagala · Martin Bues · Steven Frank · Samir H. Patel · Atsushi Musha · Tatsuya Ohno · Nancy Lee · Lisa McGee
Frontiers in Oncology
doi 10.3389/fonc.2026.1979803
Review
Published
Antitumor immunity and immune-related toxicity during immune checkpoint inhibition: mechanistic overlap, tissue selectivity, and interventional evidence
Chengyan Shi · Chunhai Li · Jun Yan
Frontiers in Immunology
doi 10.3389/fimmu.2026.1958441
Original Research
Published
The multifaceted role of SsrB in S . Typhi H58 during THP-1 macrophage infection
Marion Fernandez · Soham Deolankar · Moirangthem Kiran Singh · Parisa Zangoui · Linda J. Kenney
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1849419
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Original Research
Published
Early dynamics of eosinophils and the neutrophil-to-lymphocyte ratio are associated with severe immune-related adverse events during nivolumab therapy for metastatic renal cell carcinoma
Ondřej Fiala · Jan Králíček · Jindřich Kopecký · Michal Vočka · Tomas Buchler · Hana Študentová · Jana Obertová · Beáta Rondzíková · Martin Matějů · Dominik Šafčák · Matej Hrnčár · Peter Priester · Martina Spisarová · Anežka Zemánková · Radka Lohynská · Michaela Tkadlecová · Lucie Grmelová · Petr Stránský · Bohuslav Melichar · Patrik Palacka · Alexandr Poprach
Frontiers in Immunology
doi 10.3389/fimmu.2026.1944728
Review
Published
Chimeric antigen receptor-engineered cell therapy for asthma: advances in targeting type 2 inflammation and translational challenges
Yifei Niu · Chenyang Jian · Peize Liu · Mengwei Wu · Haoyuan Li · Xu Li · Lili Zhi
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979396
Original Research
Published
Clinical-scale manufacturing of CD137+ enriched tumor-reactive T cells for glioblastoma in the CliniMACS Prodigy
Arina Riabinska · Elvira Criado-Moronati · Emre Balta · Denis Frison · Cristina Berganza-Irusqueta · Tümay Telatar · Donata Maciaczyk · Johanna Engeln · Laura Fischer · Marieke Domdey · Imran Siddiqui · Velita Miranda · Teresa Schmidt · Sied Kebir · Yahya Ahmadipour · Martin Glas · Ulrich Herrlinger · Matthias Schneider · Anna-Laura Potthoff · Marcus Czabanka · Thomas Broggini · Sofia Stenqvist · Lisa M. Nilsson · Jonas A. Nilsson · Martina Ott · Andrzej Dzionek · Ian R. Hardy
Frontiers in Immunology
doi 10.3389/fimmu.2026.1866645
Systematic Review
Published
Efficacy of beta-blockers in preventing cardiotoxicity in breast cancer patients receiving anthracyclines: a GRADE-assessed systematic review and meta-analysis with trial sequential analysis
Victor M. Samperio · Lorena M. Murrieta Bruciaga · Jesús Antonio Castañeda Martínez · Vanessa Coronado Porchas · Alejandro Chen Liang · Yeison Cruz Castillo · Aishwarya Ghonge · Aishwarya Saripalli · Thomas Schulz
Frontiers in Cardiovascular Medicine
doi 10.3389/fcvm.2026.1926758
Case Report
Published
Multiple sclerosis relapse following gamma knife radiosurgery for meningioma in a patient treated with natalizumab: case report
Maryna Turbinska · Nabeela Nathoo · Penelope Smyth
Frontiers in Oncology
doi 10.3389/fonc.2026.1959731
Case Report
Published
Durable partial response with low-dose, intermittent nivolumab in combination with gemcitabine for high PD-L1 metastatic triple-negative breast cancer: a case report
Po Lin Ooi · Jamin Munchar Elias · Francis Yew Fu Tieng
Frontiers in Oncology
doi 10.3389/fonc.2026.1964934
Original Research
Published
Tumor-antigen-specific polyclonal antibodies suppress tumor growth and metastasis in heterogeneous solid tumors
Carine Ciron · Ophélie Dauphouy · Pierre Morice · Pierre-Joseph Royer · Gwenaëlle Evanno · Juliette Rousse · Françoise Shneiker · Bernard Vanhove · Odile Duvaux · Firas Bassissi
Frontiers in Oncology
doi 10.3389/fonc.2026.1947593
Original Research
Published
Study on the promoting effect of microplastic exposure on prostate cancer migration and invasion based on network toxicology and single-cell sequencing technology
Haiyang Jiang · Ying Bi · Longguo Dai · Yong Zhu · Ruikang Zhang · Chen Hu · Hong Yang · Jun Li · Chongjian Zhang · Yu Bai · Ruiqian Li
Frontiers in Oncology
doi 10.3389/fonc.2026.1973812
Case Report
Published
Case Report: Ribociclib-associated bilateral neurotrophic keratitis requiring amniotic membrane transplantation during adjuvant treatment of early breast cancer
Danielle DeCicco · Sanjana Nethagani · Lingo Lai · Danish Safi
Frontiers in Oncology
doi 10.3389/fonc.2026.1932226
Review
Published
Microplastic contamination in agricultural systems: impacts on plant productivity, economic losses, and supply chain resilience
Tong Xu
Frontiers in Plant Science
doi 10.3389/fpls.2026.1956066
Original Research
Published
Antimicrobial activity of ginsenoside Rh2 against Enterococcus faecalis and its biofilm
Chaoran Liu · Yanchun Wang · Shu Zhou · Guanghong Han · Yingxian Zhai
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1979316
Mini Review
Published
Phytogenic zinc oxide nanoparticles in breast cancer therapy: an ethnopharmacological perspective on multi-targeted mechanistic pathways and translational constraints
Dhanya Soman Pillai · Ramesh Narve Venkatesha · Amarnath Karavettekudy Ranjit · Zeena Subramonia Pillai
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1883009
Systematic Review
Published
Carrier-free self-assembled nanodrugs in cancer therapy: a systematic scoping review and evidence map of molecular architecture, drug resistance, and translation-relevant reporting
Yifei Wang · Lulan Ma · Jiangshan Hu · Yanqiu Liu · Bonian Zhao · Yan Gao
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1977190
Review
Published
Application of natural products combined with plant-derived extracellular vesicles in cancer therapy
Ruyue Wang · Menglin Ren · Yuanjian Xu · Yan Sun · Zenghui Xu
Experimental Biology and Medicine
doi 10.3389/ebm.2026.11329
Original Research
Published
Assessment of the transcriptional and cellular effects of CRISPRa targeting Dopa decarboxylase and GTP cyclohydrolase 1 in HEK293 and SH-SY5Y cellular models of Parkinsonian neurotoxicity
Siyethaba Zinhle Bhengu · Ravesh Singh · Veron Ramsuran · Zama Ndlondlo Princess Msibi
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1883789
Review
Published
Leishmaniasis and vaccine development: current progress, challenges, and future perspectives
Somaditya Dey · Anushka Ghosh · Debarati Mukherjee
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1929424
Original Research
Published
Diethyl fumarate exhibits potent activity against differentially culturable Mycobacterium tuberculosis persisters
Amelie J. Herbert · Obolbek Turapov · Fraser MacDonald · Irawaty Djaharuddin · Muhammad Nasrum Massi · Douglas B. Kell · Vadim A. Makarov · Galina V. Mukamolova
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1901638
Systematic Review
Published
Forensic source classes and toxic-equivalent concentrations of polycyclic aromatic hydrocarbons in soils and sediments: a systematic review and meta-analysis
Vaibhav Sharma · Mahipal Singh Sankhla · Anuj Sharma · Kumud Kant Awasthi · Rachit Manchanda · Vishwanil Suman · Yogesh Kumar · Rupesh Gupta · Rajeev Kumar · Garima Awasthi
Frontiers in Earth Science
doi 10.3389/feart.2026.1948291
Original Research
Published
A chemically tuned La@MOF-808 adsorbent for simultaneous removal of Per- and polyfluoroalkyl substances (PFAS), arsenic, and lead from aqueous solutions
Hassan Nawaz · Gregg P. Kotchey · David V. P. Sanchez
Frontiers in Materials
doi 10.3389/fmats.2026.1804165
Original Research
Published
A melatonin textile transdermal patch based on physicochemical synergistic permeation-enhancement strategy for circadian rhythm regulation
Juyang Zhao · Jinzhi Liu · Jiahan Lin · Mingtao Liu · Fujun Wang · Lu Wang · Jing Gao
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1913854
Original Research
Published
Multi-omics integration reveals the role of PFOS in sarcopenia via ESRRG and RBP4: from computational prediction to experimental validation
Xingyao Yang · Xin Wang · Shuxing Xing · Zhangzhen Du
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1926144
Review
Published
Artificial intelligence - driven toxicogenomics for predictive environmental and pharmaceutical safety
Mohammed Monirul Islam · Sibghatullah Muhammad Ali Sangi · Girish Meravanige · Sreeharsha Nagaraja · Muhammad Shahzad Chohan · Md Khalid Anwer · Ashesh Gurung
Frontiers in Genetics
doi 10.3389/fgene.2026.1858338
Original Research
Published
Associations between a series of composite glucose-lipid indices and moderately increased albuminuria in patients with type 2 diabetes mellitus: a cross-sectional study
Yaru Li · Zhenyu Pan · Xinbo Zhao · Guanqi Gao · Dan Fu · Baolan Ji
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1883785
Original Research
Published
Reduction of Candidatus Liberibacter asiaticus titres in citrus seedlings via root-drenching application of bio-based nanoemulsions
Vitória Rodrigues Bergamo · Vítor Rodrigues Marin · Caio Felipe Cavicchia Zamunér · Lucas Miotelo · Maicon Segalla Petrônio · Henrique Ferreira
Frontiers in Agronomy
doi 10.3389/fagro.2026.1965184
Systematic Review
Published
Selenium supplementation for preventing cancer therapy-related toxicities: a systematic review and meta-analysis of clinical trials
Chuyue Chang · Juncheng Wei · Mengfei Li · Tingyi Chang · Yakun Guo · Miao Jiang
Frontiers in Nutrition
doi 10.3389/fnut.2026.1940806
Original Research
Published
Bioremediation of lead and manganese from wastewater using different Bacillus spp. with FTIR spectroscopic analysis
Walaa M. Nasr · Mohamed A. El-Kammah · Mohamed A. S. Abdelrazek · Hassan E. Flefel · Hossam Khedr · Nada A. El-Morsy · Mohamed E. Elmasry
Frontiers in Environmental Science
doi 10.3389/fenvs.2026.1936478
Review
Published
The genotoxic burden of toxic metals: bridging molecular mechanisms, biomonitoring, and multidisciplinary interventions
Sameera Reem Imthiaz · Suryapratap Ray · Gracy Anu Francis · Rahul Vashishth
Frontiers in Toxicology
doi 10.3389/ftox.2026.1906308
Original Research
Published
ZnPc(Lys) 5 -mediated photodynamic inactivation and reduction of Candida albicans biofilm-associated cells in vitro and in vivo
Danlin Li · Fang Yuan · Yuchen Yang · Kangli Zhou · Fei Xie · Zhiming Li · Xiaoling Huang · Mingdong Huang · Minkui Lin
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1953510
Original Research
Published
Natural polysaccharide-engineered POP@ZIF-67 nanoparticles coordinate antibacterial activity, macrophage polarization, and osteogenesis for chronic osteomyelitis therapy
Yunchang Zhao · Guangting Zhu · Mengxue Zhang · Yize Wu · Junwei Su · Jing Hu · Chao Jian · Ying Yuan
Frontiers in Bioengineering and Biotechnology
doi 10.3389/fbioe.2026.1935416
Review
Published
Liver-resident cellular determinants of oncolytic virotherapy in hepatocellular carcinoma: viral susceptibility and spatial immune remodeling
Ding Hu · Qiong Wang
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1959317
Original Research
Published
EPA and DHA engage NRF2 to orchestrate a β-cell resilience circuit suppressing senescence remodeling and sustaining molecular fitness during glucolipotoxic stress
Chaofeng Xing · Fanghong Li · Yan Zou · Cheng Song · Dan Luo · Jian Ruan · Minyi Tang · Qihua Xu · Yunping Mu · Jie Shen · Allan Zijian Zhao
Frontiers in Physiology
doi 10.3389/fphys.2026.1948763
Mini Review
Published
Periodontal diseases and coronary artery disease: epidemiological links, pathogenic mechanisms and prospects for comorbidity integrated management
Chengkui Xu · Tong Yu · Lulu Zhang
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1946319
Review
Published
Gut microbiota dysbiosis in pediatric acute lymphoblastic leukemia: clinical consequences, mechanistic insights, and microbiota-targeted interventions
Ke Chen · Qingqing Li · Yun Xing · Changqi Liu · Fei Yang
Frontiers in Pediatrics
doi 10.3389/fped.2026.1928304
Technology and Code
Published
An integrative meningioma surfaceome atlas and a transferable framework for CAR-T target nomination
Vivek Sanker · Dhanya Mahesh · Linda Liverani · Matthew Alexander Abikenari · Zhikai Li · Yi Zhang · Debebe Theodros · Ravi Medikonda · Maria Jose Cavagnaro · Matei Alexandru Banu · Atman Desai · Michael Lim
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1919802
Original Research
Published
Polystyrene nanoplastics impair mitochondrial function, quality control, and ER–mitochondria crosstalk in HeLa cells
Giuseppe Petito · Maria Teresa Gentile · Arianna Cuomo · Angelo Fusco · Sara Falvo · Maria della Valle · Gianluca D’Abrosca · Carla Isernia · Roberto Fattorusso · Maria Emanuela Errico · Antonia Lanni · Gaetano Malgieri · Rosalba Senese
Frontiers in Toxicology
doi 10.3389/ftox.2026.1907794