Perspective
Published
Artificial intelligence for small-molecule chemical probe design: why drug-centric models may not transfer cleanly
Renzo Carlucci · Exequiel O. J. Porta
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1836983
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 858 articles
Review
Published
From biosimilars to breakthroughs: regulatory convergence toward evidence-efficient development of monoclonal antibodies
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1778468
Systematic Review
Published
Rebound regrowth phenomenon in patients with pediatric low-grade gliomas treated with MAPK inhibitors – a systematic review
Malgorzata Styczewska · Weronika Lyzinska · Malgorzata A. Krawczyk · Ewa Bien
Oncology Reviews
doi 10.3389/or.2026.1815932
Original Research
Published
Light-driven growth rate-dependent volatile organic compound production reflects adaptative strategies in Dunaliella tertiolecta and Thalassiosira weissflogii
Hawra H. Almubarak · Holger H. Buchholz · Kimberly H. Halsey
Frontiers in Photobiology
doi 10.3389/fphbi.2026.1810167
Original Research
Published
Assessing ecosystem risk from human activities in an Atlantic oceanic island
Ana C. Suhett · Débora S. Ferrari · Sergio R. Floeter · Ana M. Liedke · Tiago B. R. Gandra · Amanda R. Rodrigues · Hudson T. Pinheiro · Raphael M. Macieira · João L. Gasparini · Vinicius J. Giglio · Maria A. Gasalla · Carlos E. L. Ferreira
Frontiers in Ocean Sustainability
doi 10.3389/focsu.2026.1721755
Original Research
Published
Opposite sides of different coins: near-diametrical opposition of physiological indices of reduced accuracy of face emotion recognition in schizophrenia and autism spectrum disorders
Daniel C. Javitt · Antigona Martinez · Pejman Sehatpour · Pamela D. Butler · Elisa Dias · Kristin Micceri · Melissa Breland · Russell H. Tobe
Frontiers in Neuroimaging
doi 10.3389/fnimg.2026.1771087
Original Research
Published
Surgical management of ulcerative colitis-associated colorectal cancer in a 20-year period, a single-centre study
János Tajti · László Libor · Szabolcs Ábrahám · Zsolt Simonka · Anikó Maráz · Attila Paszt · Tamás Molnár · Judit Oláh · György Lázár
Pathology and Oncology Research
doi 10.3389/pore.2026.1612362
Commentary
Published
Governing Evidence in Contentious Times: A GUARD Framework for Public Health Leadership
Geneviève Chene · Marie Preau · Paulette Lenert · Yves Martin-Prevel · Roch Giorgi
Public Health Reviews
doi 10.3389/phrs.2026.1609645
Original Research
Published
Rate maximization of low-altitude integrated sensing and communication systems with fluid antennas
Siyun Liang · Xingtao Yang · Zhenghe Guo · Zhaohui Yang · Chen Zhu · Zhaoyang Zhang
Frontiers in Communications and Networks
doi 10.3389/frcmn.2026.1783301
Brief Research Report
Published
Genome analysis of Ceratobasidium theobromae and its causal association with cassava witches’ broom disease in the Philippines
Cris Q. Cortaga · Alejandra Gil-Ordóñez · Mónica F. Fronda · John Emmanuel B. Tandang · Juan M. Pardo · Ana M. Leiva · Warren Arinaitwe · Clarise Marie S. Evaristo · Jonathan Newby · Al Imran Malik · Wilmer J. Cuellar
Frontiers in Fungal Biology
doi 10.3389/ffunb.2026.1800255
Original Research
Published
Investigation on partial acidulation of rock phosphate using acetic acid and acidic calcium phosphate solutions
Youness Sedki Alaoui · Yuriy Sakhno · Pavlo Ivanchenko · Mohamed Hafidi · Martin Jemo · Deb P. Jaisi
Frontiers in Chemical Engineering
doi 10.3389/fceng.2026.1779902
Review
Published
Analytical similarity as the primary determinant of monoclonal antibody development: toward evidence-efficient regulatory frameworks
Sarfaraz K. Niazi
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1801236
Original Research
Published
Collateral status predicts functional outcome in early-treated large-core anterior circulation stroke
Andrés Gallardo · Pablo M. Lavados · Pablo Albiña-Palmarola · Gabriel Cavada · Andrés Roldán · Verónica V. Olavarría
Frontiers in Stroke
doi 10.3389/fstro.2026.1755828
Original Research
Published
Random timing of aversive events extends stress responses in fish
Patricia Tatemoto · Graziela Valença-Silva · Donald Maurice Broom · Mônica Serra
Frontiers in Ethology
doi 10.3389/fetho.2026.1716575
Review
Published
Advanced computational approaches for bioheat transfer in minimally invasive cancer thermal therapies
Neetu Singh
Frontiers in Thermal Engineering
doi 10.3389/fther.2026.1798897
Original Research
Published
Are community-delivered patient navigation interventions the answer for targeting colorectal cancer screening inequalities? Findings from Lancashire's “Call for a KIT” intervention
Sandro Tiziano Stoffel · Shahida Hanif · Lorraine Morris · Robert Kerrison · Yasemin Hirst · Christian Von Wagner
Frontiers in Cancer Control and Society
doi 10.3389/fcacs.2026.1518293
Mini Review
Published
Epi-liquidomics: redefining cancer diagnostics through epigenetic profiling
Shahper Nazeer Khan · Mohammad Harris Siddiqui · Aamir Ahmad · Luca Guarnera · Salamatu Tijjani Isah
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1813822
Review
Published
Beyond GLP-1: underexplored peptide–receptor systems as the next frontier in drug discovery
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1792418
Brief Research Report
Published
Evaluating transport service quality metrics in tourism: a technological innovation-driven approach
Akhmatova Mokhigul Ergash Qizi · Qodirov Azizjon Anvarovich · Urakova Dilfuza Bakhriddinovna
Frontiers in Future Transportation
doi 10.3389/ffutr.2026.1797151
Review
Published
The invasive spectacled caiman (Caiman crocodilus) in Florida, United States: invasion timeline, insights, and implications for Everglades restoration
Sergio A. Balaguera-Reina · Edison D. Bonilla-Liberato · Bryna L. Daykin · Frank J. Mazzotti
Frontiers in Amphibian and Reptile Science
doi 10.3389/famrs.2026.1778412
Mini Review
Published
Postpartum challenges in women with systemic autoimmune diseases
Dina Zucchi · Chiara Tani · Giancarlo Cascarano · Elena Elefante · Marta Mosca
Frontiers in Lupus
doi 10.3389/flupu.2026.1788752
Review
Published
A registry-based systematic review of lifestyle and non-pharmaceutical oncology interventions in Africa
Monica Wangari · Eunice Njoroge · Grace Mburu · Brenda Mogeni · Luke Ouma
Frontiers in Cancer Control and Society
doi 10.3389/fcacs.2026.1571038
Editorial
Published
Editorial: Non-tuberculous mycobacteria and bronchiectasis
Octavio M. Rivero-Lezcano · Ramiro López-Medrano · Jaime Esteban
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1819209
Mini Review
Published
The anesthesiologist's role in preventing chronic post-surgical pain and opioid use through neurobiological programming: a mini review
Trisha Nair · Ofelia Loani Elvir-Lazo · Robert Wong
Frontiers in Anesthesiology
doi 10.3389/fanes.2026.1766035
Brief Research Report
Published
Promoting engagement with a mental health smartphone app: evidence from a randomized field experiment
Adeline Delavande · Nathan Kettlewell · Beate Mueller · Rachael Murrihy · Sonal Singh
Frontiers in Behavioral Economics
doi 10.3389/frbhe.2026.1700973
Perspective
Published
Re-opening the question of lower SARS-CoV-2 attack rates in active smokers: a perspective on viral interference and Tobacco Mosaic Virus
Ernesto de Bernardis · Fabio Lugoboni · Lina Busà · Giulio Petronio Petronio · Roberto Di Marco
Frontiers in Virology
doi 10.3389/fviro.2026.1801380
Correction
Published
Correction: Effect of hydroponic cultivation using MPM-processed methane fermentation digestate on tomato growth and yield
Dannisa Fathiya Rachma · Kazuya Maeda · Yuta Yamanouchi · Hiroshi Ueda · Kimiko Yamamoto · Makoto Shinohara · Masahide Isozaki · Dong-Hyuk Ahn
Frontiers in Horticulture
doi 10.3389/fhort.2026.1813573
Mini Review
Published
Species barriers in AAV tropism: mechanisms, models, and emerging solutions for clinical translation
Xinyuan Xu
Acta Biochimica Polonica
doi 10.3389/abp.2026.15939
Original Research
Published
Shifting expectations: when knowledge-based predictions and linguistic context collide
Melissa Troyer · Kara D. Federmeier
Frontiers in Language Sciences
doi 10.3389/flang.2026.1768590
Review
Published
Oral delivery of peptides and proteins: pharmacokinetic boundaries, negative selection, and route triage
Sarfaraz K. Niazi
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1776167
Original Research
Published
Transperineal versus transrectal systematic prostate biopsy in routine clinical practice: a real-world comparative study
Anouar El Ghazzaly · Mohammed Mrabeti · Abdesamad El Bahri · Larbi Hamedoun · Mohammed Tetou · Mohammed Alami · Ahmed Ameur
Frontiers in Urology
doi 10.3389/fruro.2026.1806961
Original Research
Published
Quaternized modified waste wood-derived porous carbon electrode for highly selective capacitive deionization denitrification
Sumei Zheng · Qin Liu · Xiaomei Huang · Maochun Wei · Furong Tu · Haomei Liu · Meina Xie · Xiaoqing Zhang · Huiju Zhang
Frontiers in Chemical Engineering
doi 10.3389/fceng.2026.1792131
Mini Review
Published
Metal-based compounds and Chagas disease treatment: current knowledge and therapeutic perspectives
Vitor Klipel da Silva Bertolini · Jennyfer Castro · Josielle Vieira Fontes · Camilla Abbehausen · Fernanda Ramos Gadelha
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1765208
Technology and Code
Published
Extra-P—Empirical performance modeling made easy
Alexandru Calotoiu · Marcin Copik · Fabian Czappa · Alexander Geiss · Gustavo de Morais · Marcus Ritter · Sergei Shudler · Torsten Hoefler · Felix Wolf
Frontiers in High Performance Computing
doi 10.3389/fhpcp.2025.1714042
Original Research
Published
Synergistic removal of various emergent pollutants in biochar-enhanced constructed wetlands: a pilot-scale nature-based solution for municipal wastewater treatment improvements
Chaimae Maldou · Yasmina El Janoussi · Dhafer Mohammed M. Al Salah · Majida Lahrouni · Naaila Ouazzani · Tonni Agustiono Kurnaiwan · Ayoub El Ghadraoui · Amine Elleuch · Aroua Ammar · John Poté · Faissal Aziz
Frontiers in Environmental Chemistry
doi 10.3389/fenvc.2026.1762724
Case Report
Published
Incidental detection of PDAC via 18 F-PSMA PET/CT in a patient with recurrent prostate cancer. A case report
Giordano Savelli · Mattia Bonacina · Alberto Soffientini · Elvira Archiati · Claudio Bnà · Alberto Zaniboni
Frontiers in Nuclear Medicine
doi 10.3389/fnume.2026.1767321
Brief Research Report
Published
Age-related dopaminergic integrity in the SNpc and VTA: morphometric and volumetric findings in marmoset ( Callithrix jacchus )
Maria M. O. Azambuja · Nelyane N. M. de Santana · Paulo L. A. G. Morais · Gabriel A. M. Vasiljevic · Jeferson S. Cavalcante · Adhil Bhagwandin · José R. L. P. Cavalcanti · Rovena Clara Engelberth
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1768392
Review
Published
Direct-to-satellite internet of things (DtS-IoT): a tutorial review on architectures, protocols, and future directions
Serdar Akar · Alessandro Compagnoni · Juan A. Fraire · Roberto Garello
Frontiers in Communications and Networks
doi 10.3389/frcmn.2026.1750955
Original Research
Published
Foam cleaning in closed circuits: effect of surfactant type on foam structure and Bacillus subtilis spore removal from stainless steel surfaces
Ahmad Al Saabi · Heni Dallagi · Piyush Kumar Jha · Fethi Aloui · Thierry Benezech · Christine Faille
Frontiers in Soft Matter
doi 10.3389/frsfm.2026.1750630
Review
Published
Methyl-coenzyme M reductase in archaeal methanogenesis: evolution, mechanism, and biotechnological perspectives
Alberto Vázquez-Salazar · Ricardo Hernández-Morales · Edgar Mixcoha · Ricardo Muñiz-Trejo · Israel Muñoz-Velasco
Frontiers in Catalysis
doi 10.3389/fctls.2026.1778429
Original Research
Published
CRISPR/Cas9-mediated knockout of DFR alters pigmentation and shifts flavonoid accumulation in red leaf lettuce without detectable growth penalties
Ai Nagamine · Masaki Ono · Osuke Sato · Eiji Goto · Hiroshi Ezura
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1755922
Original Research
Published
Postnatal expression of the transcription factor Ebf2 in motivation, reward, and pain-related circuits of the mouse brain
Moisés Martínez-Estrada · M. Blanca D. Cepeda-Varela · A. Damaris Salinas-Villarreal · Mara C. Obregón-Fuentes · Danna A. Real-Marín · Melani A. Balderas-Díaz · Viviana Zomosa-Signoret · Jesús Santana-Solano · Moisés Santillán-Zerón · Román Vidaltamayo
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1780361
Mini Review
Published
Social learning and exploration–exploitation dilemma in decision-making
Gota Morishita · Shinsuke Suzuki
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1781811
Original Research
Published
Effects of various alternative stunning techniques on welfare indicators and meat quality of Nile tilapia
Arnan Hirunratanakorn · Jidapa Yamkasem · Natthakul Youngnoi · Piyathip Setthawong · Win Surachetpong · Tuchakorn Lertwanakarn
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1779691
Original Research
Published
Field evaluation of a topical combination of ivermectin, imidacloprid, and praziquantel for flea control in cats under routine clinical
Camilo Romero-Núñez · Ariadna Flores-Ortega · Rafael Heredia-Cárdenas · Enrique Salazar-Grosskelwing
Frontiers in Parasitology
doi 10.3389/fpara.2026.1755999
Original Research
Published
Search for marker proteins to assess blood–brain barrier development
Yukari Shigemoto-Mogami · Kimiko Nakayama-Kitamura · Kaoru Sato
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1717532
Original Research
Published
Intra- and extrapulmonary lipopolysaccharides-induced acute lung injury and pharmacotherapeutic response patterns in ventilated 7-day-old rabbits
Guiyin Zhuang · Qiang Gu · Siyu Xie · Xiaojing Guo · Bo Sun
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10788
Original Research
Published
Bathing in resistance: evidence of multidrug-resistant bacteria in recreational coastal waters in Niterói City, Rio de Janeiro, Brazil
Sofia Lessa Costa · Laura Brandão Martins · Milena Conceição Amorim · Marcos Tavares Carneiro · Viviane Zahner · Thiago Pavoni Gomes Chagas
Frontiers in Bacteriology
doi 10.3389/fbrio.2025.1718905