Review
Published
Therapeutic reprogramming of natural killer cells for solid tumors: expanding frontiers into rare and ultra-rare malignancies
Francesca Rosato · James W. Hodge
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1955532
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 137 articles
Original Research
Published
Combined exposure to emerging Fusarium mycotoxins produces concentration-dependent synergistic toxicity in Jurkat T cells
Chanamon Maleeratana · Phattarawadee Wattanasuntorn · Saranya Poapolathep · Imourana Alassane-Kpembi · Johanna Fink-Gremmels · Isabelle P. Oswald · Amnart Poapolathep
Frontiers in Toxicology
doi 10.3389/ftox.2026.1924250
Original Research
Published
Balancing acidity in low alcohol wines: effects of fermentation conditions, chemical modification, and yeast selection on consumer perception
Patricia C. Patricio-Morillo · Madelyn M. Rippo · Alexandra A. Escalera · Charles Sims · Katherine A. Thompson-Witrick · Amarat Simonne · Andrew J. MacIntosh
Frontiers in Food Science and Technology
doi 10.3389/frfst.2026.1926825
Original Research
Published
Cross-species gene expression analysis identifies a type I interferon-associated transcriptional signature in Tregs from atopic dermatitis
Naoya Kase · Hina Nakamura · Chizuru Nakakomi · Manami Shimakata · Mai Banno · Ryotaro Kanari · Yohsuke Harada
Journal of Cutaneous Immunology and Allergy
doi 10.3389/jcia.2026.17310
Original Research
Published
Adoptive T Cell therapy for cancer and autoimmune disease: current advances, challenges, and future directions
Qiu-Hong Bao · Angel Wu · Jianming Pang · Junwei Wang · Qingqing Chen · SuWen Wu
Oncology Reviews
doi 10.3389/or.2026.1905358
Review
Published
The future directions of CAR-T Cell therapy: unlocking the potential of immunotherapy in cancer treatment
Angel Alberto Justiz-Vaillant · Sachin Soodeen · Rodolfo Arozarena-Fundora · Patrick Eberechi Akpaka · Chandrashekhar Unakal
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1931159
Perspective
Published
Tregs and persistent P. gingivalis colonisation: a plausible mechanism for cardiovascular risk in edentulism
Jelena Roganović
Frontiers in Oral Health
doi 10.3389/froh.2026.1895121
Mini Review
Published
Bridging soil health and human health: Mycobacterium vaccae as a keystone link
Camila Espinoza-Mendoza · Winfred Espejo · José E. Celis · Andy Banegas-Medina · Isis-Yelena Montes · Wanda Espejo-Contreras · Mauricio Schoebitz · Marco Sandoval
Frontiers in Soil Science
doi 10.3389/fsoil.2026.1957461
Original Research
Published
First report of Ichthyobodo necator, a flagellate protozoan parasite, in Schizothorax niger from the River Jhelum in the Kashmir Himalayas, India
Ishrat Shafi · Asifa Wali · Feroz A. Shah · Gowhar Iqbal · Shabir Ahmad Dar · Nazir Ah Sofi
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1846130
Case Report
Published
Clinicopathological features and differential diagnosis of a case report of atypical spindle cell/pleomorphic lipomatous tumor
Cheng Wang · Yuwen Jiang · Qinghua Liu · Yiqi Wang
Frontiers in Musculoskeletal Disorders
doi 10.3389/fmscd.2026.1922243
Review
Published
Clinical translation of CRISPR-Cas9 therapeutics in cancer and inherited genetic disorders
Khushi Bashir · Prathiksha Vasudev · Vikas Chhetri · Devika Prasad Dubhashi · Yash Gurunath Teli · Rhitam Biswas · Sudha Ramaiah · Anand Anbarasu
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1868779
Review
Published
Pathological neural and immune synapses in glioblastoma progression: mechanisms and therapeutic opportunities
Ashwin Jainarayanan · Aishwarya Vedula · Neeraj Soni
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1919817
Original Research
Published
Genes and cells associated with sublingual allergen immunotherapy revealed by integrated transcriptome analysis in allergic rhinitis patients
Zhengqi Li · Yilin Hou · Hang Li · Ding Ji · Yi Wei · Renqiang Ma
Frontiers in Allergy
doi 10.3389/falgy.2026.1855863
Original Research
Published
Adaptive immune cells and kidney function in older adults: sex-specific associations in the health and retirement study (HRS)
Shannon M. Sullivan · Bibin Joseph · Shweta Sharma · Weihua Guan · Amy B. Karger · Jessica Faul · Bharat Thyagarajan
Frontiers in Aging
doi 10.3389/fragi.2026.1882462
Brief Research Report
Published
High-titer human packaging cells producing γ-retroviral vectors pseudotyped with engineered baboon endogenous retrovirus (BaEV) envelope proteins
Angelina Hallik · Mona Pißarreck · Mats Jürgen Grummel · Yasemin van Heuvel · Jörn Stitz
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1888550
Review
Published
A narrative review of stellate ganglion block in management of post-operative atrial fibrillation with focus on immunomodulatory mechanisms
Dandan Zhu · Misty A. Radosevich · Aneta Szofer-Sendrowska · Maciej M. Kowalik · Wen Li · Erica Wittwer · Daniel Diedrich · Krzysztof Laudanski
Frontiers in Anesthesiology
doi 10.3389/fanes.2026.1898474
Original Research
Published
Delay-driven infection resurgence and intervention timing in within-host HIV infection
Sayaphat Suksai · Suthep Suantai · Areeyuth Sama-Ae
Frontiers in Applied Mathematics and Statistics
doi 10.3389/fams.2026.1899461
Review
Published
Secreted proteins of Mycobacterium tuberculosis as therapeutic targets for drug discovery
Anthony Musaazi Kaweesa · Divya Tiwari
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1736139
Original Research
Published
Octenidine selectively disrupts membrane-coupled photosynthetic functions in intact purple bacteria
Péter Maróti
Frontiers in Photobiology
doi 10.3389/fphbi.2026.1841679
Original Research
Published
In-host modeling of Tfh–Tfr–fCD8+ T cell dynamics on HIV reservoir persistence
Faraimunashe Chirove · Koffi Messan Agbavon
Frontiers in Applied Mathematics and Statistics
doi 10.3389/fams.2026.1875113
Original Research
Published
A Mycobacterium tuberculosis rare variable antigen vaccine reduces lung pathology in hypersusceptible SP140 −/− mice
Zachary P. Howard · Alexander Mohapatra · Weihao Zheng · Joel D. Ernst
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1814646
Perspective
Published
Development of automated biosensor technologies for future biological research beyond low Earth orbit
Neha Lingam · Alina Shkurikhina · Jasmine W. Wu · Dunya M. Shuman · Sergio R. Santa Maria
Frontiers in Space Technologies
doi 10.3389/frspt.2026.1877143
Review
Published
CAR-T cell therapy in glioblastoma: from αβ to γδ T-cell platforms
Costanza Dieli · Roberta Costanzo · Anna Maria Corsale · Federica Paolini · Marta Di Simone · Claudia Avellone · Francesco Dieli · Domenico Gerardo Iacopino · Salvatore Marchiafava · Rosario Maugeri · Serena Meraviglia
Oncology Reviews
doi 10.3389/or.2026.1808229
Methods
Published
Production of virus-like particles with AsCas12a nuclease and CMV-driven crRNA for mammalian genome editing
Natalia A. Kruglova · Sofiia E. Borovikova · Mikhail V. Shepelev
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1735339
Frontiers in Science Lead Article
Published
Regulatory T cells: master orchestrators of immune tolerance and tissue homeostasis
Jeffrey A. Bluestone · Megan K. Levings · Frederick J. Ramsdell · Alexander Y. Rudensky · Qizhi Tang · Piotr Trzonkowski
Frontiers in Science
doi 10.3389/fsci.2026.1792210
Frontiers in Science Viewpoint
Published
Treg therapy needs better trials
Fadi Issa · Kathryn Wood
Frontiers in Science
doi 10.3389/fsci.2026.1874873
Original Research
Published
Essential oil from Artemisia gmelinii extenuates cellular integrity of Sporothrix globosa and its biofilms by steering intracellular ROS and basal ergosterol levels
Acharya Balkrishna · Manisha Kabdwal · Monali Joshi · Yash Varshney · Meenu Tomer · Pardeep Nain · Savita Lochab · Anurag Varshney
Frontiers in Fungal Biology
doi 10.3389/ffunb.2026.1842749
Hypothesis and Theory
Published
The cells of origin of the chemotherapy-curable malignancies are highly sensitive to cytotoxic chemotherapy-mediated cell death
Emily Proudman · Philip Savage
Frontiers in Hematology
doi 10.3389/frhem.2026.1814036
Original Research
Published
Acute myocardial infarction induces sex-specific, time-dependent remodeling of the gut microbiome and intestinal immune compartment in retired breeder C57BL/6N mice
Eszter Pal · Neda Omidi Arjenaki · Yao Lu · Jianguo Xia · Lorraine Chalifour
Frontiers in Microbiomes
doi 10.3389/frmbi.2026.1818652
Mini Review
Published
Persistent low-level HIV viremia: a narrative review of diagnostic predicaments, virological pathomechanisms, and clinical outcomes
Shanmugam Saravanan · Ramachandran Vignesh · Madhavan Vidya · Sathasivam Sivamalar · Pachamuthu Balakrishnan · Esaki M Shankar · Marie Larsson
Frontiers in Virology
doi 10.3389/fviro.2026.1807017
Original Research
Published
Connexin 43 enhances liver metastatic ability of GIST cells in vivo
Takako Kihara · Jiayin Yuan · Takashi Yamasaki · Makoto Yoshida · Mizuka Ohkouchi · Yuka Nakaya-Hashikura · Neinei Kimura · Kanae Hyodo · Chisato Ohe · Seiichi Hirota
Pathology and Oncology Research
doi 10.3389/pore.2026.1612383
Systematic Review
Published
Signaling pathway mechanisms in pancreatic ductal adenocarcinoma tumor microenvironment and emerging targeting strategies for improved prognosis
Tosin Akinsipe · Caroline O. Odewumi · Lekan Latinwo · Omorose O. Aghimien · Musiliyu A. Musa · Philip O. Igbinoba · Anthony L. Simons · Monica O. Aghimien
Oncology Reviews
doi 10.3389/or.2026.1814540
Original Research
Published
Single-cell mechanoprofiling of aging and cancer using AFM probes coated with RGD ultrashort peptide nanofibers
Manola Moretti · Vanesa Gámez-Báez · Dana Alhattab · Sherin Abdelrahman · Rosario Montserrat Pérez-Pedroza · Panayiotis Bilalis · Malak Abedalthagafi · Christian Baumgartner · Charlotte A. E. Hauser
Frontiers in Nanotechnology
doi 10.3389/fnano.2026.1652880
Original Research
Published
Proof-of-principle 4-marker spatial profiling reveals distinct, location-independent immune clusters in biliary tract cancers
Federico Rossari · Michele Sala · Margherita Rimini · Silvia Camera · Mara Persano · Giovanni Tonon · Chiara Bonini · Maria Giulia Cangi · Lorenza Pecciarini · Claudio Doglioni · Maurilio Ponzoni · Chiara Balestrieri · Federica Pedica · Andrea Casadei-Gardini
Pathology and Oncology Research
doi 10.3389/pore.2026.1612389
Original Research
Published
Comparative reactivity studies of imine-copper(II) and zinc(II) complexes containing both oxindole and benzimidazole scaffolds for biomolecules and tumor cells
Aline Monteiro L. Zaballa · Ana Paula Araujo de Oliveira · Rodrigo B. Fazzi · Raphael E. F. de Paiva · Katherine Tsantarlis · Carla Columbano Oliveira · Maciel Santos Luz · Sayuri Miyamoto · Ana M. da Costa Ferreira
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1666012
Original Research
Published
Conversion from resistance to susceptibility: a dirty trick by PM 10
Sharon A. McClellan · Mallika Somayajulu · Farooq S. Muhammed · Robert Wright · Linda D. Hazlett
Frontiers in Environmental Health
doi 10.3389/fenvh.2026.1766012
Review
Published
Offense-defense in bone infection: interferon regulation and the immune evasion of Staphylococcus aureus
Jinrong Qian · Weiwei Qian · Xiaoyu Tang · Yin Yang
Frontiers in Bacteriology
doi 10.3389/fbrio.2026.1757036
Review
Published
Sirtuin 1 is a key molecular link between cellular senescence and heart failure
Jan Krekora · Jarosław Drożdż · Janusz Blasiak
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1818104
Original Research
Published
Immunometabolic reprogramming of Mycobacterium tuberculosis -responsive memory CD4 + T cell subsets is linked to long-term protective immunity
Vaishnavi Kaipilyawar · Samantha Leong · Arianne Lovey · Lorenzzo L. Stringari · Reynaldo Dietze · Jerrold J. Ellner · Rodrigo Ribeiro-Rodrigues · Padmini Salgame
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1783887
Original Research
Published
Development of in planta genome editing by transient expression of genome-editing tools in tomato
Misaki Kobayashi · Na Renhu · Shu Takahashi · Seungje Choi · Haruto Watanabe · Martina Bianca Fuhrmann-Aoyagi · Hiroshi Ezura · Kenji Miura
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1777148
Editorial
Published
Editorial: Advances and new horizons in cellular therapies for leukemia and myeloma
Bhavana Bhatnagar · Srinivas Devarakonda
Frontiers in Hematology
doi 10.3389/frhem.2026.1812817
Original Research
Published
Efficacy of a novel thermo-reversible wound gel against antibiotic tolerant biofilm
Jeyachchandran Visvalingam · Anna Muzaleva · Miloslav Sailer · Sarvesh Logsetty · Robert B. Huizinga
Frontiers in Antibiotics
doi 10.3389/frabi.2026.1773630
Original Research
Published
A novel de novo ATP2B1 variant causes autosomal dominant intellectual developmental disorder 66 by disrupting calcium homeostasis via impaired membrane trafficking
Huanhuan Zang · Xiaoyun Yang · Yucai Liu · Caiyun Ma · Dawei Yang
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10834
Review
Published
Skeletal muscle reprogramming in peripheral nerve injury: mechanisms, therapeutic roles, and complication management
Fuqiang Long · Xiaoru Pan · Anxin He · Xinlu Wang · Zairong Wei · Shaoying Gao
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10835
Original Research
Published
Identification of potential hub genes related to ferroptosis and hypoxia in dilated cardiomyopathy: a bioinformatic analysis with preliminary experimental validation
Xiqin Wang · Chrismis Novalinda Ginting · William Leslie
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10709
Original Research
Published
L-Glutamine attenuates peritoneal fibrosis developed in 5-Fluorouracil-treated mice
Juliana Francisca Grossi Heleno · Leticia Cristine Cardoso dos Santos · Igor Campos Fontes · Mirielly Ranny Almeida Paiva Silva · Lucas Barbosa Correia · Nayma Drielly Granato Silva · Pedro Henrique Dias Moura Prazeres · Pedro Pires Goulart Guimarães · Derek W. Gilroy · Silvia Passos Andrade · Paula Peixoto Campos
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10755
Review
Published
The role of necroptosis as a possible therapeutic target in multiple myeloma: the emerging roles of necroptosis
Duygu Aydemir
Frontiers in Hematology
doi 10.3389/frhem.2026.1686097
Hypothesis and Theory
Published
Bilateral rhythmic stimulation as a possible modulator of meningeal lymphatic flow: a regulatory T cell–centered neuroimmune hypothesis of eye movement desensitization and reprocessing
Ioulia Milovanov
Frontiers in Integrative Neuroscience
doi 10.3389/fnint.2026.1758529