Hypothesis and TheoryPublished 12 October 2026Integrating Control-Mastery Theory and EMDR in the treatment of attachment-related trauma: pathogenic beliefs, testing processes, and target selectionLudovica Bedeschi · Margherita OnofriFrontiers in Psychologydoi 10.3389/fpsyg.2026.1918050
Systematic ReviewPublished 9 October 2026Towards optimizing repetitive transcranial magnetic stimulation protocols for chronic subjective tinnitusDibyendu Das · Koyel Das · Henry Benson Nongrum · Indranil Chatterjee · Dinesh BhatiaFrontiers in Audiology and Otologydoi 10.3389/fauot.2026.1955517
Original ResearchPublished 9 October 2026Metaphors' journeys across time and genre: tracking the evolution of literary metaphors with temporal embeddingsVeronica Mangiaterra · Chiara Barattieri di San Pietro · Paolo Canal · Valentina BambiniFrontiers in Language Sciencesdoi 10.3389/flang.2026.1828340
Hypothesis and TheoryPublished 9 October 2026A SynNotch-PiggyBac gene circuit for inflammation-responsive IL-10 delivery in Alzheimer’s disease: a hypothesis and design frameworkSuhani Gupta · Ronav GuptaFrontiers in Aging Neurosciencedoi 10.3389/fnagi.2026.1866161
ReviewPublished 9 October 2026The global emergence of Trichophyton indotineae: epidemiology, resistance, and management challengesDipika Shaw · Adnan Omar · Michelle Singh · Merin Chandanathil · Chandana Bhargavi · Nagaraj Mysore · Dharam Bir · Srinidhi Ramasamy · Prasanna HonnavarFrontiers in Tropical Diseasesdoi 10.3389/fitd.2026.1960706
Hypothesis and TheoryPublished 9 October 2026The cingulate–mitochondrial–resonome axis: a conceptual framework integrating rehabilitation, interoception, and affective–motor processing in canine chronic painHolly Pollard-Wright · Alexandra KlomhausFrontiers in Pain Researchdoi 10.3389/fpain.2026.1807872
Mini ReviewPublished 9 October 2026Pain, cognition, and culture in dementia research: a critical synthesis of empirical and methodological literatureRimsha Taqdees · Tom Mercer · Abigail Olubola TaiwoFrontiers in Pain Researchdoi 10.3389/fpain.2026.1797629
Original ResearchPublished 9 October 2026Age-associated remodeling of NK cell subsets, B cell subsets, and T cell surface markers in peripheral blood of healthy Chinese adults: a prospective multicolor flow cytometry studyLiyuan Zheng · Wei Cao · Yixuan Wang · Tengda Xu · Fada Wang · Leidan Zhang · Xinchao Liu · Taisheng LiFrontiers in Agingdoi 10.3389/fragi.2026.1847033
PerspectivePublished 9 October 2026From health trackers to compasses: can wearables and apps deliver on their health prevention promise?S. M. Goodday · A. Goldenberg · F. Doshi-Velez · S. H. FriendFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1967226
Hypothesis and TheoryPublished 9 October 2026Immunometabolic synaptopathy: linking metabolic syndrome to epileptogenesis through trained immunity and parvalbumin interneuron vulnerabilityBaihui Zhang · Wenjin Wang · Tao Li · Hua HuangFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.1979155
Original ResearchPublished 9 October 2026Development and application of a targeted MISCP-S intervention model for psychiatric hospitalsJing Du · Xin Jiang · Qiwen Li · Xin Liu · Gang Qing · Yan Yang · Mi YangFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1799863
Study ProtocolPublished 9 October 2026Sitting Baduanjin-based rehabilitation programme following endovascular therapy in patients with chronic limb-threatening ischemia: protocol for a WeChat mini program-assisted multicentre randomized controlled trialJiayi Song · Li Fu · Xiaomei Fang · Haiyan Chen · Lian Wang · Liang Xing · Huanping Liu · Yun XuFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1921616
Original ResearchPublished 9 October 2026Comprehensive coronary computed tomography angiography assessment in high-altitude diabetic populations: integrating plaque characteristics, pericoronary inflammation, and coronary functionXin Fang · Shuang Li · Zhetao Wang · Junyan Zhang · Jia Song · Bing Wu · Kang Li · Kaiyue DiaoFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1886360
Original ResearchPublished 9 October 2026Circulating and vascular NAD + metabolism remodeling in Tgαq*44 mice with progressive heart failureAgata Jedrzejewska · Oliwia Krol · Patryk Mucha · Ada Kawecka · Ewa Slominska · Mariola Olkowicz · Ryszard T. Smolenski · Marta TomczykFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1927197
ReviewPublished 9 October 2026Canine atopic dermatitis clinical trials: study design and methodological considerationsMichael Klotsman · Sharon K. Sagiv · Wayne H. Anderson · Domenico SantoroFrontiers in Veterinary Sciencedoi 10.3389/fvets.2026.1878714
ReviewPublished 9 October 2026A proposed framework for practical multimodal management of osteoarthritis in adult dogsDenis J. Marcellin-Little · Janice Huntingford · Tamara Grubb · Arielle Pechette Markley · Matthew W. Brunke · Donald A. Hulse · Bethany FrankFrontiers in Veterinary Sciencedoi 10.3389/fvets.2026.1864824
Original ResearchPublished 9 October 2026Development and external validation of an explainable machine learning model for identifying depressive symptoms in middle-aged and older adults with low haemoglobin: a prediction-model studyQilong Wang · Juan He · Siheng Ma · Jianpeng Zhao · Jingjing Zong · Dongmei Ma · Sha Liu · Lei Zhang · Xin Qi · Dongrong ZhaoFrontiers in Nutritiondoi 10.3389/fnut.2026.1846276
Original ResearchPublished 9 October 2026Influence of yoga on the epigenetics of obesity: a study on its short- and medium-term benefits in the treatment of patients with severe/morbid obesity eligible for bariatric surgeryCarmela Asteria · Giorgia Scichilone · Rosanna Cardani · Dejan Lazarevic · Valentina Milani · Federico Ambrogi · Laura Valentina Renna · Marco Morelli · Francesca Giannese · Anna Sofia Tascini · Nicoletta Caridi · Fabiana Barbieri · Michela Ravelli · Alessandro GiovanelliFrontiers in Public Healthdoi 10.3389/fpubh.2026.1858629
Study ProtocolPublished 9 October 2026Effects of the AI-HEALS intervention based on the Fogg behavior model on self-management in postoperative breast cancer patients: a randomized controlled trial study protocolLidan Heng · Jing Wang · Siyu Chen · Zixu Zhang · Wei Zhang · Lihua Nie · Weina Lv · Dandan Yang · Sen Li · Huitao WangFrontiers in Public Healthdoi 10.3389/fpubh.2026.1909032
Original ResearchPublished 9 October 2026Factors associated with reduced kidney function in hospitalized children with dehydrationDovilė Ruzgienė · Georgios Stathoglou · Inga Ivaškevičienė · Augustina JankauskienėFrontiers in Pediatricsdoi 10.3389/fped.2026.1917450
Original ResearchPublished 9 October 2026Relative timelines for transition from a hospital ventilator to invasive home respiratory support after tracheostomy in infants with chronic respiratory failureMegan Ottomeyer · Noah Hillman · Justin Josephsen · Paula Buchanan · Howard Williams · Kurtis T. SobushFrontiers in Pediatricsdoi 10.3389/fped.2026.1887686
Case ReportPublished 9 October 2026Osteopathic manipulative treatment as an adjunct therapy in a pediatric patient with chronic pancreatitis and visceral hyperalgesia: a case reportAvrohom Levy · Haili Bach · Fernando Medina Carbonell · Aniruddh SetyaFrontiers in Medicinedoi 10.3389/fmed.2026.1839129
Original ResearchPublished 9 October 2026Low arterial oxygen-content burden during the first 24 h and hospital mortality in mechanically ventilated adults: analyses of MIMIC-IV and eICUXiaoyan Gao · Jiaqi Wang · Luyan Xiong · Bingzhu Hu · Cheng Jiang · Juan Li · Shi Chen · Cong ZhangFrontiers in Medicinedoi 10.3389/fmed.2026.1935082
Case ReportPublished 9 October 2026Extensive vulvar and perianal langerhans cell histiocytosis with clinical improvement during low-dose thalidomide and topical therapy: a case reportPan Zou · Xiao Mei ZhuFrontiers in Medicinedoi 10.3389/fmed.2026.1969330
Original ResearchPublished 9 October 2026Explainable machine learning for preoperative prediction of acute kidney injury after intertrochanteric fracture surgery in older adultsWeizhang Lin · Ximing Lin · Hongpeng GaoFrontiers in Medicinedoi 10.3389/fmed.2026.1961926
Original ResearchPublished 9 October 2026Single cell RNA-seq analysis identifies junctional adhesion molecule two positive endothelial cells aggravate osteoarthritis by mediating vascular permeability and macrophage adhesionYang Xing · Chengxin Li · Chao Wang · Linli Zheng · Puyi ShengFrontiers in Cell and Developmental Biologydoi 10.3389/fcell.2026.1937741
Original ResearchPublished 9 October 2026Tirzepatide versus other glucose-lowering therapies and risk of COPD exacerbations in patients with comorbid type 2 diabetes: a retrospective cohort studyWan-Hsuan Hsu · Yang-En Chan · Jheng-Yan Wu · Yao-Ming Chuang · Chia-Yu Kuo · Bo-Wen Shiau · Po-Yu Huang · Chih-Cheng LaiFrontiers in Pharmacologydoi 10.3389/fphar.2026.1917340
Original ResearchPublished 9 October 2026Cannabidiol preserves astrocyte viability and attenuates injury-induced glial stress responses across zebra finch song control nucleiDylan A. Marshall · Karen A. Litwa · Ken SoderstromFrontiers in Pharmacologydoi 10.3389/fphar.2026.1972787
Original ResearchPublished 9 October 2026Influence of self-reported vascular health and physical activity level on intravoxel incoherent motion imaging response to exercise in chronic low back painFrederique Dupuis · David B. Berry · Alexia Lau · Lara Havandjian · Zachary Brumm · Anirudh Anand · Armin Zavareh · Samuel R. Ward · Kamshad Raiszadeh · Bahar ShahidiFrontiers in Physiologydoi 10.3389/fphys.2026.1925680
Study ProtocolPublished 9 October 2026Effect of epidural spinal cord stimulation combined with personalized neurorehabilitation in chronic motor-complete spinal cord injury: study protocol for the phase II single-arm feasibility RESTORES (RESToration Of Rehabilitative function with Epidural spinal Stimulation) trialKai Rui Wan · Zhi Yan Valerie Ng · Seng Kwee Wee · Fatimah Misbaah · Wen Li Lui · Min Wee Phua · Tegan Plunkett · Neethu Robinson · Aung Aung Phyo Wai · Cuntai Guan · Ananda Sidarta · Rosa Qi Yue So · Brian Premchand · Kezia Susanto · Luca Cocchi · Seyed Ehsan Saffari · Rui Xin Justin Ker · Wai Hoe NgFrontiers in Neurologydoi 10.3389/fneur.2026.1967078
ReviewPublished 9 October 2026Polyclonal IgG therapy in neurologic and neuromuscular disease: mechanisms of action and insights from newer therapiesMel BergerFrontiers in Neurologydoi 10.3389/fneur.2026.1819474
ReviewPublished 9 October 2026Beyond the light-driven pacemaker: the suprachiasmatic nucleus as a dynamic coordinator of environmental cuesTao Zhang · Kai Huang · Jing Yu · Shaojun Wu · Qiaocheng ZhaiFrontiers in Neurosciencedoi 10.3389/fnins.2026.1937340
ReviewPublished 8 October 2026Nutrition, thyroid function, and tuberculosis: exploring the endocrine–immune axisNooneh Khachatourian · Rubina Takhmazian · Vishwanath VenketaramanFrontiers in Tuberculosisdoi 10.3389/ftubr.2026.1945832
Original ResearchPublished 8 October 2026Understanding parental trauma in caring for children with down syndrome within LSEN school settingsHabeeb Omoponle Adewuyi · Veronica M. DwarikaFrontiers in Child and Adolescent Psychiatrydoi 10.3389/frcha.2026.1926429
Hypothesis and TheoryPublished 8 October 2026Altered body representation in chronic non-specific low back pain: a testable framework linking body-schema-related disturbance, corticomotor alterations, and altered pain processingZhifei XieFrontiers in Pain Researchdoi 10.3389/fpain.2026.1899538
PerspectivePublished 8 October 2026From disease activity scores to precision medicine: biomarkers and composite models for risk stratification in chronic spontaneous urticariaShuayb Elkhalifa · Mohamed AbuzakoukFrontiers in Allergydoi 10.3389/falgy.2026.1962595
Study ProtocolPublished 8 October 2026Co-designing accessible digital mindfulness for veterans with spinal cord injury: protocol for developing and testing VA CALM-SCI for virtual realityHilary Touchett · Kathryn Kanzler · Zina Trost · Jan Lindsay · Felicia SkeltonFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1923501
Original ResearchPublished 8 October 2026Status and influencing factors of self-care among patients with chronic heart failure and their spouses from a dual perspective: a cross-sectional studyXiaoyan Wu · Yiyu Zhuang · Manjun Wang · Jinhua Jin · Jun Xie · Yuting KeFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1818518
Original ResearchPublished 8 October 2026Long-term survival after transcatheter aortic valve implantation in nonagenarian patients: a multicenter real-world studyGianluca Pagnoni · Marco Loffi · Dalia Caleffi · Susan Darroudi · Giuseppe Masaracchia · Benedetta Frassoni · Francesco Marangi · Sophia di Michele · Davide Gabbieri · Luciano Losi · Alberto Monello · Fabio Alfredo Sgura · Salvatore Arrotti · Rosario Rossi · Daniele Iaccarino · Marco Ruozzi · Vincenzo Guiducci · Filippo Luca Gurgoglione · Giorgio Benatti · Luigi Vignali · Giampaolo Niccoli · Giuseppe Boriani · Daniela Aschieri · Francesca CoppiFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1945453
ReviewPublished 8 October 2026Vascular aging biomarkers: the role of ADMA, SDMA, and inflammationAleksandra Melnitskaia · Liubov Machekhina · Valentina Pykhtina · Alexey Churov · Olga Maltseva · Wu Zhenghi · Olga Tkacheva · Irina StrazheskoFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1922813
Systematic ReviewPublished 8 October 2026Berberine and metabolic dysfunction-associated steatotic liver disease: a global analysis of molecular mechanisms, translational challenges and research frontiersFei Yu · Sihan Yin · Jiayu Zhu · Kewei SunFrontiers in Nutritiondoi 10.3389/fnut.2026.1969017
Case ReportPublished 8 October 2026Case Report: Pediatric deep vein thrombosis: when pain in the leg becomes a telltale signGeorgina G. Balyorugulu · Eunice Barnabas · Nshoma Malole · Haniye Almasi · James MakorereFrontiers in Medicinedoi 10.3389/fmed.2026.1909309
Mini ReviewPublished 8 October 2026Metabolic rewiring at the obesity–estrogen–polyamine axis in endometrial cancer: emerging mechanisms and translational opportunitiesDaniel Simancas-Racines · Dolores Jima Gavilanes · Andri Matos · Gabriele Davide Bigoni-Ordóñez · Claudia Reytor-GonzálezFrontiers in Cell and Developmental Biologydoi 10.3389/fcell.2026.1954981
Original ResearchPublished 8 October 2026Direct RNA sequencing-based multi-omics profiling reveals transcriptional and post-transcriptional remodeling in mice with diet-induced atherosclerosisXin Liu · Xueyu Han · Wenjun Qiu · Fengming Guo · Yan Guo · Yipeng Gao · Yuxin Liu · Ruichen Xu · Ke Hu · Bo ShenFrontiers in Cell and Developmental Biologydoi 10.3389/fcell.2026.1953461
Original ResearchPublished 8 October 2026Amomum tsao-ko volatile oil alleviates renal fibrosis in 5/6 nephrectomy rats through TGF- β 1/SMAD3 and PI3K/AKT signaling pathwaysHuanyue Cui · Meiru Shi · Qing Xu · Shangwen Zhou · Xin Li · Hangyu Wang · Dahong Yao · Ke Zhang · Pinghua Sun · Jinhui WangFrontiers in Pharmacologydoi 10.3389/fphar.2026.1819932
Original ResearchPublished 8 October 2026Availability and reimbursement of fixed-dose combination medicines for hypertension treatment in Central and Eastern EuropeRafał Nowak · Przemysław Holko · Iris Hoxha · Alexandra Savova · Pero Draganić · Jana Skoupa · Agnes Männik · Zoltán Kaló · Arturs Praskilevics · Kristina Garuoliene · Ljubica Shuturkova · Elena Chitan · Natasa Duborija-Kovacevic · Michał Owca · Ioana Bianchi-Manaila · Nikola Stefanovic · Tomas Tesar · Tamás Ágh · Paweł KawalecFrontiers in Pharmacologydoi 10.3389/fphar.2026.1889485
EditorialPublished 8 October 2026Editorial: Herbal medicine for the treatment of chronic metabolic diseases, volume IIYongsheng ChenFrontiers in Pharmacologydoi 10.3389/fphar.2026.1952901
Original ResearchPublished 8 October 2026Comparative evaluation of antifibrotic activity of Salvadora persica extracts in CCl4-induced liver fibrosis in rats by reducing oxidative stress and inflammation via transcriptional modulation associated with TGF-β1/Smad signaling pathwayFouzia Latif · Bilal Ahmed · Hamad Z. Alkhathlan · Muhammad Saad Majeed · Afia Muhammad Akram · Qurat-ul-ain Ahmad · Shehla Akbar · Sabira Sultana · Hailing Ding · Farhan Sachal Cyprian · Merajuddin khanFrontiers in Pharmacologydoi 10.3389/fphar.2026.1900981