Review
Published
Neuro-regulatory drug discovery (NRGDD): a neural-circuit framework for systemic therapeutic modulation
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1782364
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 66 articles
Review
Published
Beyond GLP-1: underexplored peptide–receptor systems as the next frontier in drug discovery
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1792418
Specialty Grand Challenge
Published
Revisiting the grand challenges: the road travelled and ahead at the frontiers of computer-aided drug design
José L. Medina-Franco
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1780834
Mini Review
Published
Standardization of canine infections for the development of antileishmanial drugs
A. I. Olías-Molero · M. J. Corral-Caridad · M. D. Jiménez-Antón · M. Mateo-Barrientos · J. Carrión · J. J. Torrado · J. M. Alunda
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1754269
Original Research
Published
The “yeast-drop” treatment protocol in the Drosophila model for rapid and cost-effective TB drug testing
Maria Vidal · Esther Fuentes · Nerea Escobar · Marta Arch · Pere-Joan Cardona
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1746664
Perspective
Published
Acinetobacter baumannii: challenges presented by a drug-resistant pathogen
E.K. Goncalves · L.A. Ramos · A. Seibert · L.M. Ribeiro · S.L. McDuffie · M.C. Murray · S.E. Fiester
Frontiers in Bacteriology
doi 10.3389/fbrio.2025.1734537
Original Research
Published
Enhancing structure-based virtual screening of MDM2–p53 inhibitors: a benchmark of machine learning vs. traditional docking scoring functions
Marcia Yineth Castillo Tarazona · Gian Pietro Miscione
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1731262
Mini Review
Published
Zebrafish models for neurological disorders: a platform for natural product-based drug discovery
Anamica Chauhan · Thiyagarajan Raviraj · Ranbir Chander Sobti · Arpan Dutta · Monu Kumar Shukla · Michal Korinek
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1679580
Brief Research Report
Published
Workflow for the isolation of natural product secondary metabolites using off-line SPE guided by gradient reverse-phase liquid chromatography (LCSPE- fast)
Lyamara M. O. Pavão · Marília F. Barbosa · Ana Maria S. Pereira · Quezia B. Cass · Adriana A. Lopes
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1726849
Lab on a Chip Technologies
Published
Advancements and challenges in culturing patient-derived cancer cells for personalized therapeutics
Yatian Fu · Bee Luan Khoo · Chwee Teck Lim
Frontiers in Lab on a Chip Technologies
doi 10.3389/frlct.2025.1663420
Natural Products
Published
aNP-TRAP: a conceptual platform for in situ microbial cultivation and functional detection of antimicrobial activity
Maxwel Adriano Abegg
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1617079
Natural Products
Published
Methyl jasmonate and salicylic acid synergism enhances phloroglucinol content in shoot cultures of Astragalus fruticosus Forssk
Rawia Zayed · Ashraf El-Sayed · Ahmed M. Elissawy · Wafaa Ismaeil · Mohamed El-Shazly · Shaimaa Fayez
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1618336
Health Archive
Published
Behavioral signature of trihexyphenidyl in the TOR1A (DYT1) knockin mouse model of dystonia
Ahmad Abdal Qader · Yuping Donsante · Jeffrey E. Markowitz · H. A. Jinnah · Chethan Pandarinath · Ellen J. Hess
Dystonia
doi 10.3389/dyst.2025.15034
Parasitology
Published
Guanine derivatives as promising candidates for the development of purine-based antimalarial drugs
Worlanyo Tashie · Harry P. de Koning · Nancy O. Duah-Quashie · Neils B. Quashie
Frontiers in Parasitology
doi 10.3389/fpara.2025.1634209
Natural Products
Published
Recent advancement of cyanobactins and cyanobactin prenyltransferases from 2021 to 2024
Abujunaid Habib Khan · Chin-Soon Phan
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1616031
Analytical Science
Published
Kallikrein immobilized on magnetic beads for activity-based assays using mass spectrometry
Camila Loreta Rocha · Carmen Lúcia Cardoso
Frontiers in Analytical Science
doi 10.3389/frans.2025.1514381
Analytical Science
Published
The chemicalome profiling of Zishen Yuzhen Pill in vivo and its promoting effect on osteogenic differentiation of MC3T3-E1 cells
Juanjuan Cheng · Xinyue Meng · Daozheng Fang · Yong Zhu · Zhihao Liu · Xinyue Li · Ke Jie · Shiying Huang · Huilin Li · Shangbin Zhang · Jihang Chen · Jianping Chen
Frontiers in Analytical Science
doi 10.3389/frans.2025.1533486
Acoustics
Published
Detaching cells in culture medium using forced vibration for removing a centrifugation from culture process
Hayato Shimoguchi · Chikahiro Imashiro · Kenjiro Takemura
Frontiers in Acoustics
doi 10.3389/facou.2024.1502136