Editorial
Published
Editorial: Targeting cancer metabolic reprogramming for cancer therapy
Werner J. Geldenhuys · Haitao M. Ji · Hoang V. Le
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1916506
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 66 articles
Review
Published
The ERK MAPK pathway in mesenchymal glioblastoma: tumorigenesis, microenvironmental reprogramming, and the therapeutic promise of RAS(ON) multi-selective inhibition
Uma M. Basole · Mary M. Fitzpatric · Joseph Donohoe · Shashank Obulasetti · William Snider · Emily Haugen · Damir Garcia · Ana Gonzalez-Manteiga · Mathieu Sertorio · Marc Oria
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1857885
Original Research
Published
In vitro cytotoxic and anti-inflammatory activities of Ayapana triplinervis essential oil and hydroethanolic extract
Lucas Gabriel V. Barbosa · Luana de Sousa P. Barros · Alexandre Motta da Silva · Leandra Feliz Santos · Renata Cunha Silva · Carlos Vinícius A. da Silva · Raphael Oliveira de Figueiredo · Flavia Cristina A. Lucas · Laine Celestino Pinto · Joyce Kelly da Silva · Hector Henrique F. Koolen · Pablo Luis B. Figueiredo
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1888636
Original Research
Published
SR9009 regulates macrophage polarization via the NR1D1/NF-κB axis to ameliorate obesity-associated ulcerative colitis
Zhixue Zheng · Xuan Cai · Yaqi Liu · Jingtao Bi
Frontiers in Gastroenterology
doi 10.3389/fgstr.2026.1762028
Brief Research Report
Published
Anti-leishmanial activity and dereplication using GC-MS assisted by molecular networking of the essential oil from the leaves and inflorescence of Melaleuca viminalis (myrtaceae)
Ana Clara L. N. Silva · Marisi G. Soares · Eduard Choi Jr. · Gabriela V. Araujo Flores · Luiz Felipe D. Passero · Márcia D. Laurenti · Patrícia Sartorelli
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1826685
Original Research
Published
Differential roles of resident lung macrophages during control of murine alveolar and airway Mycobacterium abscessus infection
Kelsey C. Haist · Jack H. Congel · Jodi M. Corley · Alma E. Ochoa · Jazalle McClendon · Patrick S. Hume · Jerry A. Nick · William J. Janssen · Kenneth C. Malcolm · Katherine B. Hisert
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1781507
Systematic Review
Published
Signaling pathway mechanisms in pancreatic ductal adenocarcinoma tumor microenvironment and emerging targeting strategies for improved prognosis
Tosin Akinsipe · Caroline O. Odewumi · Lekan Latinwo · Omorose O. Aghimien · Musiliyu A. Musa · Philip O. Igbinoba · Anthony L. Simons · Monica O. Aghimien
Oncology Reviews
doi 10.3389/or.2026.1814540
Original Research
Published
Proof-of-principle 4-marker spatial profiling reveals distinct, location-independent immune clusters in biliary tract cancers
Federico Rossari · Michele Sala · Margherita Rimini · Silvia Camera · Mara Persano · Giovanni Tonon · Chiara Bonini · Maria Giulia Cangi · Lorenza Pecciarini · Claudio Doglioni · Maurilio Ponzoni · Chiara Balestrieri · Federica Pedica · Andrea Casadei-Gardini
Pathology and Oncology Research
doi 10.3389/pore.2026.1612389
Perspective
Published
Convergent mitochondrial toxicity of fluorinated agents in oncological anaesthesia: sevoflurane, 5-fluorouracil, and the ACOD1/itaconate immune axis
Ivan N. Dushin
Frontiers in Anesthesiology
doi 10.3389/fanes.2026.1839640
Original Research
Published
Deciphering the role of the Sch9 serine/threonine kinase in Scedosporium apiospermum
Samar Kabbara · Hajar Yaakoub · Baptiste Bidon · Charlotte Godon · Bienvenue Razafimandimby · Yves Delneste · Pascale Pignon · Jean-Philippe Bouchara · Monzer Hamze · Nicolas Papon
Frontiers in Fungal Biology
doi 10.3389/ffunb.2026.1820509
Original Research
Published
Conversion from resistance to susceptibility: a dirty trick by PM 10
Sharon A. McClellan · Mallika Somayajulu · Farooq S. Muhammed · Robert Wright · Linda D. Hazlett
Frontiers in Environmental Health
doi 10.3389/fenvh.2026.1766012
Review
Published
Offense-defense in bone infection: interferon regulation and the immune evasion of Staphylococcus aureus
Jinrong Qian · Weiwei Qian · Xiaoyu Tang · Yin Yang
Frontiers in Bacteriology
doi 10.3389/fbrio.2026.1757036
Original Research
Published
Identification of potential hub genes related to ferroptosis and hypoxia in dilated cardiomyopathy: a bioinformatic analysis with preliminary experimental validation
Xiqin Wang · Chrismis Novalinda Ginting · William Leslie
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10709
Original Research
Published
L-Glutamine attenuates peritoneal fibrosis developed in 5-Fluorouracil-treated mice
Juliana Francisca Grossi Heleno · Leticia Cristine Cardoso dos Santos · Igor Campos Fontes · Mirielly Ranny Almeida Paiva Silva · Lucas Barbosa Correia · Nayma Drielly Granato Silva · Pedro Henrique Dias Moura Prazeres · Pedro Pires Goulart Guimarães · Derek W. Gilroy · Silvia Passos Andrade · Paula Peixoto Campos
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10755
Case Report
Published
Case Report: two cases of idiopathic plasmacytic lymphadenopathy subtype of idiopathic multicentric Castleman disease with xanthelasma palpebrum from a Canadian center
Andrew A. Y. Chen · Vivian T. Yin · Paula Blanco · Mark Trinder · Richard I. Crawford · Ryan Henrie · Stephen Parkin · Nasreen Khalil · Mollie Carruthers · Lu Zhang · Luke Y. C. Chen
Frontiers in Hematology
doi 10.3389/frhem.2026.1745884
Lupus
Published
Placental lesions in patients with antiphospholipid antibody syndrome: experience of a single tertiary-care Italian reference center
Valentina Canti · Rebecca De Lorenzo · Giulia Inguscio · Serena Girardelli · Mirko Pozzoni · Nazario Pio Tenace · Roberta Lucianò · Federica Pasi · Maria Teresa Castiglioni · Paolo Ivo Cavoretto · Patrizia Rovere-Querini
Frontiers in Lupus
doi 10.3389/flupu.2024.1459172
Biomaterials Science
Published
Macrophage variance: investigating how macrophage origin influences responses to soluble and physical cues with immortalized vs. primary cells in 2D and 3D culture
Jodi Graf · Kartik Bomb · Michael Trautmann-Rodriguez · Bader M. Jarai · Nicole Gill · April M. Kloxin · Catherine A. Fromen
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2024.1399448
Neuroscience
Published
Abiotic-biotic characterization of Pt/Ir microelectrode arrays in chronic implants
Abhishek Prasad · Qing-Shan Xue · Robert Dieme · Viswanath Sankar · Roxanne C. Mayrand · Toshikazu Nishida · Wolfgang J. Streit · Justin C. Sanchez
Frontiers in Neuroengineering
doi 10.3389/fneng.2014.00002