Original ResearchPublished 12 October 2026Independent correlates of vancomycin steady-state trough concentration among patients undergoing combined CABG and valve surgery: observational findings for intra-aortic balloon pump supportBei-bei Shao · Tao Feng · Ji-cheng Jiang · Wen-lu Xing · Ming Ni · Lu-lu Li · Chao Liu · Shu-ping Meng · Yong-cheng Ma · Ai-feng WangFrontiers in Pharmacologydoi 10.3389/fphar.2026.1888382
Original ResearchPublished 12 October 2026Electroacupuncture pretreatment attenuates myocardial ischemia/reperfusion injury-induced ferroptosis via the p53/SLC7A11/GPX4 pathwayJing Mao · Qian-Ru Guo · Yi-Pu Luo · Cong-Fei Liu · Zhen-Yang Cao · Yun-Tao Yu · Wen-Wei Wu · Xin-Yu Luan · Dan-Ning Xu · Hua Wang · Pu Chen · Song WuFrontiers in Physiologydoi 10.3389/fphys.2026.1928208
Original ResearchPublished 12 October 2026Quercetin attenuates polystyrene nanoplastic-induced intestinal barrier injury through modulation of macrophage inflammatory responsesJian Kang · Heng Yang · Yan Wang · Xin Zhang · Chunyang Zhu · Yanhong Zhou · Yanqin LiFrontiers in Pharmacologydoi 10.3389/fphar.2026.1973458
ReviewPublished 12 October 2026WRN helicase addiction in MSI-H colorectal cancer: biomarker-guided pharmacology, resistance evolution, and implications for other gastrointestinal cancersPeng Zhang · Jiangsu Gan · Hongying Wang · Yali XiongFrontiers in Pharmacologydoi 10.3389/fphar.2026.1962228
PerspectivePublished 12 October 2026Precision targeting of type 2 inflammation in COPD: identifying candidates for dupilumab therapyKezhuo Zhong · Kaiying Lv · Qun LiangFrontiers in Pharmacologydoi 10.3389/fphar.2026.1971309
Systematic ReviewPublished 12 October 2026Prognostic value of multiple biomarkers for kidney function decline in type 2 diabetes with relatively preserved kidney function: a systematic review and exploratory meta-analysisJie Hu · Xinyu Pan · Shuwu Wei · Junping WeiFrontiers in Endocrinologydoi 10.3389/fendo.2026.1938521
Original ResearchPublished 12 October 2026Metformin and atorvastatin ameliorate MASH via the AMPK/NF-κB pathwayBin Zhang · Na Li · Fang Liu · Guorui Wang · Quanwei Chen · Yiming Sun · Ni Yang · Hao Zhang · Jianjun HanFrontiers in Endocrinologydoi 10.3389/fendo.2026.1972846
Original ResearchPublished 12 October 2026Impact of unilateral salpingectomy on ovarian reserve and long-term reproductive outcomes in reproductive-aged womenYanna Zhou · Yiting YangFrontiers in Endocrinologydoi 10.3389/fendo.2026.1952475
ReviewPublished 12 October 2026Role of histone post-translational modifications in preeclampsia: from pathogenesis to diagnostic and therapeutic strategiesYuanxuan Ma · Renwei Zhang · Mengting Yang · Jingli Wang · Bo Hou · Shiguo LiuFrontiers in Endocrinologydoi 10.3389/fendo.2026.1973542
EditorialPublished 9 October 2026Editorial: Imaging biomarkers in neurodegenerative diseases: advances and challengesFrancesco Lanfranchi · Andrew R. Bender · Lucas Caldi GomesFrontiers in Aging Neurosciencedoi 10.3389/fnagi.2026.2009935
Mini ReviewPublished 9 October 2026Comparative evaluation of borneol as a context‐dependent modulator of blood-brain barrier function: barrier-restorative or permeability-enhancing agent?Xiangning Yin · Sarah Ann ThomasFrontiers in Drug Deliverydoi 10.3389/fddev.2026.1934025
Original ResearchPublished 9 October 2026Age-associated remodeling of NK cell subsets, B cell subsets, and T cell surface markers in peripheral blood of healthy Chinese adults: a prospective multicolor flow cytometry studyLiyuan Zheng · Wei Cao · Yixuan Wang · Tengda Xu · Fada Wang · Leidan Zhang · Xinchao Liu · Taisheng LiFrontiers in Agingdoi 10.3389/fragi.2026.1847033
CorrectionPublished 9 October 2026Correction: Cerebrospinal fluid lipid profiles as exploratory biomarkers for pediatric meningitis: a proof-of-concept case seriesFeng Tang · Changzhen Li · Ye Zeng · Wanjun Luo · Lei Xi · Xiaomei WangFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.2012403
ReviewPublished 9 October 2026Gene, microbiome, and anti-aging doping in sport: molecular mechanisms, detection strategies, and implications for sports rehabilitation medicineDiego CotellaFrontiers in Sports and Active Livingdoi 10.3389/fspor.2026.1984895
Original ResearchPublished 9 October 2026Evaluation of large language models for ICI-related liver injury with an emerging microbiome focusMan Sun · Dan Zang · Huan Zhou · Jun ChenFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1955356
ReviewPublished 9 October 2026Strategies for the detection and prevention of human cytomegalovirus from pregnancy to the neonatal periodPei Hu · Wenjie Chen · Ying Zhou · Mengyao Yu · Yuexinzi Jin · Xi Chen · Jiexin Zhang · Jin ZhouFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1965954
Systematic ReviewPublished 9 October 2026Effects and safety of acupuncture on inflammatory biomarkers in patients with coronary heart disease: a systematic review and meta-analysisLinghao Meng · Di Sun · Houfang Ma · Shuhan Zhao · Songyan Bai · Wenzeng Zhu · Limei Zhang · Shuai ShiFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1891405
Original ResearchPublished 9 October 2026Prognostic value of the inflammatory burden index in predicting 1-year mortality in patients undergoing cardiac resynchronization therapy for heart failureRustem Yilmaz · Kenan Toprak · Ahmet Karagoz · Osman Can Yontar · Mustafa Yolcu · Yasar Turan · Faruk Boyaci · Okan Oguzhan Ovaz · Emre Kasim Yilmaz · Enes Furkan Ozturk · Ersoy ÖzFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1934817
Original ResearchPublished 9 October 2026Baseline SII and SIRI identify immune-inflammatory susceptibility and improve risk stratification of early subclinical cardiac dysfunction during non-steroidal aromatase inhibitor therapyCenyu Li · Zhengyu Tao · Yihan Wu · Chen Wu · Zi Wang · Xiaoning Wang · Huijuan Dai · Meng Jiang · Jun PuFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1888328
Original ResearchPublished 9 October 2026Sex-dependent transcriptional and imaging responses to metformin in young-adult mice with SuHx-induced pulmonary arterial hypertensionIrene Fernández-Folgueral · María Jesús Sánchez-Guisado · Irati Aiestaran-Zelaia · Marta Beraza · Aitor Zubillaga-Unsain · Claudia Miranda-Pérez de Alejo · Amanda Marrero-Pérez de Alejo · Kinsey Mae Thorpe · Angela Frimpong · Rui Adão · Ian J. Holt · Jesús Ruiz-CabelloFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1947678
Original ResearchPublished 9 October 2026Comprehensive coronary computed tomography angiography assessment in high-altitude diabetic populations: integrating plaque characteristics, pericoronary inflammation, and coronary functionXin Fang · Shuang Li · Zhetao Wang · Junyan Zhang · Jia Song · Bing Wu · Kang Li · Kaiyue DiaoFrontiers in Cardiovascular Medicinedoi 10.3389/fcvm.2026.1886360
Original ResearchPublished 9 October 2026Short-course letrozole restores fertility in aged azoospermic dogsBao Liu · Lei Zhang · Fangzhou Zhu · Xin Jin · Taole LiuFrontiers in Veterinary Sciencedoi 10.3389/fvets.2026.1939063
Case ReportPublished 9 October 2026Nursing care of a child with cerebral palsy and multidrug-resistant bacterial pneumonia treated with bacteriophage therapy: a case reportLu Wang · Chunyan Lu · Huiwen Li · Dan LiFrontiers in Pediatricsdoi 10.3389/fped.2026.1955901
Mini ReviewPublished 9 October 2026Biomarker-guided immunotherapy in osteosarcoma: from immune microenvironment profiling to patient stratification and combination strategiesQingqing LiFrontiers in Medicinedoi 10.3389/fmed.2026.1987146
Case ReportPublished 9 October 2026Jejunal intussusception following distal gastrectomy with Billroth I anastomosis: a case reportJing Guo · Runjie Hou · Yuan Zhang · Kaimeng Wang · Xiaobiao Song · Jijun WangFrontiers in Surgerydoi 10.3389/fsurg.2026.1817048
Original ResearchPublished 9 October 2026Clinical challenges in vaccine and monoclonal antibody development against ESCAPE pathogens: insights from EMA scientific advice proceduresIgor Stojkov · Linda Marchioro · Isabelle Bekeredjian-Ding · Benjamin HofnerFrontiers in Medicinedoi 10.3389/fmed.2026.1931144
Original ResearchPublished 9 October 2026Age-related hepatic tolerance to ischemia-reperfusion injury in a rat model of extended hepatectomyDmitry G. Akhaladze · Ivan V. Tverdov · Alexander A. Andreev-Andrievskiy · Mikhail A. Mashkin · Olga Yu. Frolova · Nikolay S. GrachevFrontiers in Surgerydoi 10.3389/fsurg.2026.1902759
Systematic ReviewPublished 9 October 2026Effects of liraglutide on blood pressure and renal function in patients with type 2 diabetic nephropathy: a meta-analysis of randomized controlled trialsShengning Gao · Yudong Shan · Dongxue Ma · Xiaohong Zhou · Weijuan GaoFrontiers in Medicinedoi 10.3389/fmed.2026.1921737
Systematic ReviewPublished 9 October 2026From MRI-defined bone marrow lesions to pain, structural progression, and subchondral remodeling in knee osteoarthritis: an integrated multi-database bibliometric and text-mining analysisYousheng Zhang · Zihang ZhaoFrontiers in Medicinedoi 10.3389/fmed.2026.1903675
Original ResearchPublished 9 October 2026Functional ovarian reserve in women with Hodgkin and non-Hodgkin lymphomasFrancesca Filippi · Nicole Serra · Sabrina Comana · Giorgia Di Stefano · Marco Reschini · Paola Vigano’ · Edgardo SomiglianaFrontiers in Oncologydoi 10.3389/fonc.2026.1965843
Case ReportPublished 9 October 2026Durable biochemical and radiographic response during toripalimab treatment in MSI-high/TMB-high mCRPC: a case reportJunhang Ding · Zhengxin Liu · Jinyu Tian · Feng Wang · Chuan LiuFrontiers in Oncologydoi 10.3389/fonc.2026.1907524
ReviewPublished 9 October 2026Liquid biopsy in pancreatic ductal adenocarcinoma from diagnostic accuracy to clinical utilityKonstantinos Kossenas · Nikolaos Garmpis · Nikolaos Karountzos · Christos DamaskosFrontiers in Oncologydoi 10.3389/fonc.2026.1962181
ReviewPublished 9 October 2026From image biomarkers to treatment decisions: multimodal AI and clinical translation in gynecologic oncologyMohamad Bakir · Mohammad Khaldoun Al Masri · Yousef Mushtaha · Narmeen Shaikh · Mohammed Raddaoui · Khalid Said MohammadFrontiers in Oncologydoi 10.3389/fonc.2026.1960963
ReviewPublished 9 October 2026Progress on therapeutic mRNA vaccines for cancerSiyu Wu · Huarong Liao · Wei ZhangFrontiers in Oncologydoi 10.3389/fonc.2026.1980190
Original ResearchPublished 9 October 2026Adaptive laboratory evolution and proteomic insight on collateral sensitivity for meropenem in colistin-resistant Klebsiella pneumoniaeSevaram Singh · Lovnish Thakur · Sapna · Shailesh Kumar · Manoj Kumar · Sameer Maitry · Shailendra Mani · Niraj KumarFrontiers in Microbiologydoi 10.3389/fmicb.2026.1960299
Original ResearchPublished 9 October 2026Urbanization shapes the landscape of antibiotic resistance genes and water quality microbial markers across an urban watershedMary Bustamante · Somtopchukwu Opara · Ali Hammoud · Jared Schneider · Kara Bowles · Keshav Pokhrel · Jacob A. Napieralski · Sonia M. Tiquia-ArashiroFrontiers in Microbiologydoi 10.3389/fmicb.2026.1974267
Original ResearchPublished 9 October 2026Research trends and emerging topics in gut microbiota-derived metabolites and diabetic kidney disease: a multi-database bibliometric analysis (2014–2025)Xinyu Yang · Xiangning Huang · Yaru Shi · Yunfeng Yu · Rong YuFrontiers in Microbiologydoi 10.3389/fmicb.2026.1967850
Original ResearchPublished 9 October 2026Cannabidiol preserves astrocyte viability and attenuates injury-induced glial stress responses across zebra finch song control nucleiDylan A. Marshall · Karen A. Litwa · Ken SoderstromFrontiers in Pharmacologydoi 10.3389/fphar.2026.1972787
Original ResearchPublished 9 October 2026Phytochemical characterization and effects of Dolomiaea costus root extract on ovariectomy-induced metabolic, skeletal, and uterine alterations in ratsTahany Saleh Aldayel · Hany Salah Mahmoud · Heba M. A. Abdelrazek · Doaa H. Elsayed · Mona A. Higo · Enas E. Eltamany · Heba Nageh Gad EL-HakFrontiers in Pharmacologydoi 10.3389/fphar.2026.1841164
Mini ReviewPublished 9 October 2026Saliva-based genomic signatures for early detection of oral squamous cell carcinoma: the state and perspectives of translationHiren Hansraj Patadiya · Satya Upadhyayula · Vrunda T. AdesharaFrontiers in Geneticsdoi 10.3389/fgene.2026.1831378
ReviewPublished 9 October 2026The “mobile bricks” of human evolution: how transposable elements shaped human phenotypesGiorgia Modenini · Paolo AbondioFrontiers in Geneticsdoi 10.3389/fgene.2026.1937765
Study ProtocolPublished 9 October 2026Effect of epidural spinal cord stimulation combined with personalized neurorehabilitation in chronic motor-complete spinal cord injury: study protocol for the phase II single-arm feasibility RESTORES (RESToration Of Rehabilitative function with Epidural spinal Stimulation) trialKai Rui Wan · Zhi Yan Valerie Ng · Seng Kwee Wee · Fatimah Misbaah · Wen Li Lui · Min Wee Phua · Tegan Plunkett · Neethu Robinson · Aung Aung Phyo Wai · Cuntai Guan · Ananda Sidarta · Rosa Qi Yue So · Brian Premchand · Kezia Susanto · Luca Cocchi · Seyed Ehsan Saffari · Rui Xin Justin Ker · Wai Hoe NgFrontiers in Neurologydoi 10.3389/fneur.2026.1967078
ReviewPublished 9 October 2026Periostin in diabetic kidney disease: mechanistic insights, biomarkers, and therapeutic perspectivesXuhao Li · Yamiao Wu · Yexuan Shi · Guoliang Xiong · Lingfei Lu · Jiandong LuFrontiers in Endocrinologydoi 10.3389/fendo.2026.1979232
Study ProtocolPublished 9 October 2026Cognitive remediation in schizophrenia: efficacy and role of neuroplasticity in “top-down” and “bottom-up” mechanisms—a randomized, double-blind, treatment-as-usual-controlled study protocolJuan I. Cifuentes · Constanza Orellana · Diego Tello · Cristian Ramírez · Catalina Prieto · Jessica M. Guasti · Rodrigo R. NietoFrontiers in Psychiatrydoi 10.3389/fpsyt.2026.1936475
ReviewPublished 8 October 2026Iron-related biomarkers and Lewy body dementia: a scoping reviewJessica L. Freeling · Lisa M. McFaddenFrontiers in Aging Neurosciencedoi 10.3389/fnagi.2026.1900516
PerspectivePublished 8 October 2026From disease activity scores to precision medicine: biomarkers and composite models for risk stratification in chronic spontaneous urticariaShuayb Elkhalifa · Mohamed AbuzakoukFrontiers in Allergydoi 10.3389/falgy.2026.1962595
Mini ReviewPublished 8 October 2026Sleep and circadian disruption during human spaceflight: mechanisms, operational consequences, and countermeasuresMerel Goedegebure · Sarah BaatoutFrontiers in Space Technologiesdoi 10.3389/frspt.2026.1958668
Original ResearchPublished 8 October 2026Pathogen spectrum and triple-criteria interpretation algorithm of BALF-targeted NGS in children with refractory severe community-acquired pneumonia in mountainous Northeastern Sichuan: a single-center retrospective studyRongjie Chen · Zhe Xu · Tingting He · Xiao Liu · Yi Ding · Xin HouFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1929990