Review
Published
Gut microbiota-immune-bone axis in osteoporosis: mechanisms and intervention strategies
Minying Huang · Baocheng Xie · Hongyu Liu
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1879472
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Showing 417 articles
Review
Published
Microbiota–host crosstalk in ulcerative colitis: mechanistic evidence and translational prospects for traditional Chinese medicine
Jing Chen · Jing Du · Baoxi Mu · Jie Zhang · Guangbin Shang · Xiaojun Yan
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1956353
Original Research
Published
Histopathology-guided spatial transcriptomic analysis identifies an ECM-associated stromal pattern in lacrimal gland adenoid cystic carcinoma with complementary proteomic and functional analyses
Rong Luan · Difei Zuo · Yeqing Wang · Meixia Jiang · Xun Liu · Limin Zhu · Tingting Lin
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1949721
Original Research
Published
Polysomnographic and nocturnal heart rate correlates of cognitive impairment in Parkinson’s disease: a cross-sectional study
Zhang Linwei · Lv Pu · Wang Lu · Zhang Xiangfei · Wang Kang · Jin Miao
Frontiers in Neurology
doi 10.3389/fneur.2026.1913495
Review
Published
Periostin in diabetic kidney disease: mechanistic insights, biomarkers, and therapeutic perspectives
Xuhao Li · Yamiao Wu · Yexuan Shi · Guoliang Xiong · Lingfei Lu · Jiandong Lu
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1979232
Review
Published
Metabolic-inflammatory heterogeneity in PCOS assisted reproduction: a compartmental susceptibility model
Lin Yuying
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1963493
Review
Published
Modifiable glymphatic-related brain clearance physiology in humans: a critical narrative review of interventional evidence
Marta M. Wrzesień · Kamil Pobozy · Grzegorz Turek · Wojciech Czyzewski · Binbin Zhu · Mirosław Ząbek
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1984401
Review
Published
Neuromodulatory interventions for Alzheimer’s disease
Ruofan Wang · Botao Zhu · Qingda Guo · Jun Steed Huang · Wandong Zhang
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1925914
Systematic Review
Published
Antimalarial and antiplasmodial compounds (2024–2026): a systematic review of synthetic, semi-synthetic, and natural agents
Bertin Mikolo · Gelase Fredy Nsonde Ntandou · Hermeline Tabuna Nee Ntalani
Frontiers in Tropical Diseases
doi 10.3389/fitd.2026.1944733
Hypothesis and Theory
Published
Altered body representation in chronic non-specific low back pain: a testable framework linking body-schema-related disturbance, corticomotor alterations, and altered pain processing
Zhifei Xie
Frontiers in Pain Research
doi 10.3389/fpain.2026.1899538
Mini Review
Published
Cortical circuits linking peripheral inflammation to affective states
Dahae J. Jun · Shi Tang · Emilia Favuzzi
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1951226
Review
Published
Candida albicans subverts host programmed cell death: a unified framework from pyroptosis to ferroptosis
Limin Fan · Ruining Huang · Kexin Wang · Manting Ni · Xiuyu Nong · Zhenmou Xie · Bo Fu · Lijun Mo · Yinyuan Lan · Qingqing Xu · Wenhan Cao · Xinyue Li · Xueting Liu · Yaohua Xue
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1960578
Original Research
Published
Regulatory role and mechanism of sRNA24 targeting pqsH in Pseudomonas aeruginosa infection immunity
Huanlan Liao · Qianying Liu · Yuyang Liu · Qiwei Li · Yujuan Xiong · Lan Wang · Yang Lu
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1933779
Original Research
Published
Long-term organic fertilization enhances paddy soil nitrogen availability through direct nutrient stimulation and complementary diazotroph-mediated pathway
Li Wen · Chao Li · Kaikai Cheng · Lihong Shi · Lingling Liu · Shijie Qin · Ke Wang · Peng Jiang · Haiming Tang
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1923757
Review
Published
Gut microbiota-derived small molecules, peptides, and proteins in GPCR signaling: current evidence for β-arrestin involvement
Yushan Hu · Yiru Liu · Haiyan Yao · Siteng Wang · Yice Gao · Ruixue Li · Hui Sun
Frontiers in Microbiology
doi 10.3389/fmicb.2026.1979411
Review
Published
Decoding Zmiz1 : a key transcription coactivator in development and disease
Rajan K C · Anoushka Shenoy · Most Ayesha Siddika · Nehal R. Patel · Stryder M. Meadows · Maria J. Galazo
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1933470
Original Research
Published
Direct RNA sequencing-based multi-omics profiling reveals transcriptional and post-transcriptional remodeling in mice with diet-induced atherosclerosis
Xin Liu · Xueyu Han · Wenjun Qiu · Fengming Guo · Yan Guo · Yipeng Gao · Yuxin Liu · Ruichen Xu · Ke Hu · Bo Shen
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1953461
Systematic Review
Published
Mapping the intellectual landscape of lactylation research: a bibliometric analysis of global trends and emerging frontiers
Jieyan Wang · Zhou Li · Xiya Li · Xiyu Liu · Zhaohua Zhong · Yantong Wan · Hui Liang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1841236
Review
Published
Chinese herbal medicine for ulcerative colitis: product-level clinical evidence, mechanistic appraisal, and a roadmap to precision translation
Yingxiu Wu · Jianxiong Ren · Huibiao Li · Shiyu Qi · Wei Ke
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1976448
Original Research
Published
Gypenoside LI modulates autophagy-associated apoptosis in clear cell renal cell carcinoma by PPARG/PTEN/PI3K/AKT/mTOR/ULK1 signaling network
Ruyi Liu · Hao Yu · Hui Liu · Yujie Wei · Anxin Wang · Qi Huang · Hui Xu · Xiuming Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1956477
Review
Published
Precision medicine for futile recanalization after mechanical thrombectomy in acute ischemic stroke: mechanisms, diagnostics, and tailored therapies
Yihua Zhu · Jie Wen · Xingqi Zhao · Haoxuan Li · Gelin Xu
Frontiers in Neurology
doi 10.3389/fneur.2026.1962902
Original Research
Published
Association of leucine pathway metabolites with moyamoya disease and its clinical phenotypes
Miaoran Fu · Jixuan Xu · Tianjiao Zhang · Yueming Luo · Lijun Wang · Lulu Qi · Min Zhang · Chuming Tao
Frontiers in Neurology
doi 10.3389/fneur.2026.1875390
Original Research
Published
Cross-scale genetic, molecular, and cellular triangulation prioritizes ACSL5 as a T3-responsive candidate linking hypothyroidism liability to anemia
Hui Li · Tao Jiang · Huan Wang · Mei Wang · Sixi Xie
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1943954
Mini Review
Published
Plant essential oils as a novel therapeutic strategy for depression and anxiety: emerging evidence and mechanisms
Jiahui Hong · Liting He · Jingquan Chen · Hongxuan Cai · Weiyi Cheng · Ji-gang Piao · Jingjing Zhu
Frontiers in Psychiatry
doi 10.3389/fpsyt.2026.1920527
Review
Published
How electroacupuncture parameters shape brain responses
Ciqiu Tian · Qian Li · Fengxia Liang
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1959062
Review
Published
GLP-1 receptor agonists as potential disease-modifying agents in Parkinson’s and Alzheimer’s disease: mechanisms, clinical trial evidence, and the neuroprotection horizon
Mohamed Alsharif · Omran Shrebaty · Mohammad Ammar Aloudah · Mayar Alqahtani · Raghad Saud Aloubili · Marafi Jammaa Ahmed · Bana Albani · Ahmad El Bana
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1969490
Systematic Review
Published
Bioactivity research in Grifola frondosa: a global scientometric analysis of emerging bioactivities and translational applications
Christian Joseph N. Ong · Jamil Allen G. Fortaleza · Kevin Smith P. Cabuhat · Glocielle F. Molabola · Johnalie N. Cabalbag · Jose Jurel M. Nuevo · Jowi Tsidkenu Pili Cruz · Esperanza C. Cabrera
Frontiers in Fungal Biology
doi 10.3389/ffunb.2026.1940029
Review
Published
Deep brain stimulation and spinal cord stimulation for chronic disorders of consciousness: a decade of clinical evidence, mechanistic insights, and critical appraisal
Dongsheng Liu · Kai Yang · Jianlei An · Sipeng Zhu · Yitong Jia · Yichen Zhou · Yong Wang · Weihua Cheng · Kaihan Jiang · Yi Yang · Shaoya Yin · Lei Liu
Frontiers in Human Neuroscience
doi 10.3389/fnhum.2026.1982589
Review
Published
Biochemical and molecular mechanisms of probiotic action: current concepts and emerging therapeutic applications
Alexey A. Churin · Lyudmila O. Sokolyanskaya · Anastasia P. Lukina · Olga V. Karnachuk
Frontiers in Nutrition
doi 10.3389/fnut.2026.1964473
Mini Review
Published
Pan-cancer biomarkers of immune therapy resistance: mechanisms and clinical translation
Chao Wang · Dong Yang
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1895670
Review
Published
The 19S proteasome as a therapeutic target in hematologic malignancies
Idaly M. Olivas · Mayra A. Gonzalez-Henry · Saeedeh Darvishi · Evelyn M. Esparza · Anna M. Eiring
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1918833
Review
Published
The fast–slow stretch-shortening cycle classification: provenance, transmission and evidential status of the 250 ms boundary
Chengzhi Li · Yi Yang
Frontiers in Physiology
doi 10.3389/fphys.2026.1981174
Review
Published
Principles, concepts, and perspectives for the improvement of decompression procedures: a Neo-Haldanian approach bridging bubble physics and decompression physiology
Jean-Pierre Imbert · Ran Arieli · Costantino Balestra
Frontiers in Physiology
doi 10.3389/fphys.2026.1943519
Hypothesis and Theory
Published
The developmental dopamine trajectory hypothesis of ADHD across the lifespan
Raly James Perez Custodio · Stephan Getzmann · Edmund Wascher · Michael C. Pan · Florence Ingred Samante · Fred Lawrence Samante · Bung-Nyun Kim · Hee Jin Kim · Eugene C. Yi · Jae Hoon Cheong
Frontiers in Psychiatry
doi 10.3389/fpsyt.2026.1944446
Original Research
Published
Multi-cohort meta-analysis, single-cell and Mendelian randomization analyses with experimental validation identify RHBDF2 as a shared mediator of ulcerative colitis and blood–brain barrier disruption
Jiongjiong Cheng · Aman Xu
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1970578
Review
Published
Microplastics and nanoplastics as potential ecological oncogenic co-drivers: rewiring host–microbe interactions in cancer
Richard Ponce-Cusi · Claudia Barletta-Carrillo · Nesstor Pilco-Ferreto
Frontiers in Cellular and Infection Microbiology
doi 10.3389/fcimb.2026.1923626
Original Research
Published
Flow cytometric profiling of water buffalo milk EVs: how lactation stage drives phenotypic evolution and macrophage modulation
Barbara Canonico · Mariele Montanari · Ludovica Di Fabrizio · Giulia Franzoni · Giovanna De Matteis · Katia Cappelli · Francesco Grandoni · Maria Carmela Scatà · Daniele Lopez · Samanta Mecocci · Michela Battistelli · Tania Vanzolini · Giovanna Cappelli · Anna Donniacuo · Orlando Paciello · Caterina Ciacci · Stefano Papa · Michele Guescini · Paola Lanuti · Alessandra Martucciello
Frontiers in Veterinary Science
doi 10.3389/fvets.2026.1922591
Review
Published
Gut microbiota dysbiosis in pediatric acute lymphoblastic leukemia: clinical consequences, mechanistic insights, and microbiota-targeted interventions
Ke Chen · Qingqing Li · Yun Xing · Changqi Liu · Fei Yang
Frontiers in Pediatrics
doi 10.3389/fped.2026.1928304
Review
Published
Context-dependent oxytocin receptor signaling: from molecular architecture to transcript-level receptor engineering
Benjamin Jurek · Julia J. Winter · Daniel S. Quintana
Frontiers in Neuroscience
doi 10.3389/fnins.2026.1938379
Perspective
Published
Advances in enhanced sampling simulations of G-protein-coupled receptors
Keya Joshi · Victor Ayo Adediwura · Yinglong Miao
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1943336
Review
Published
Maternal adverse childhood experiences and epigenetic aging in pediatric populations: a scoping review
Debjani Chanda · Munawar Hussain Soomro · Jaeden Cole · Gillian England-Mason · Deborah Dewey
Frontiers in Child and Adolescent Psychiatry
doi 10.3389/frcha.2026.1913117
Original Research
Published
Polystyrene nanoplastics impair mitochondrial function, quality control, and ER–mitochondria crosstalk in HeLa cells
Giuseppe Petito · Maria Teresa Gentile · Arianna Cuomo · Angelo Fusco · Sara Falvo · Maria della Valle · Gianluca D’Abrosca · Carla Isernia · Roberto Fattorusso · Maria Emanuela Errico · Antonia Lanni · Gaetano Malgieri · Rosalba Senese
Frontiers in Toxicology
doi 10.3389/ftox.2026.1907794
Original Research
Published
Genetic algorithm–optimized SEIR-V: robust parameter estimation for wastewater-based infectious disease modeling across multiple regions
Bin Li · Sadaruddin Chachar · Chenhao Zhang · Zhang Rui · Nuoting Lu · Jieren Liu · Badaruddin Chachar · Zaid Chachar · Feijuan Huang · Yuanzhe Cai
Frontiers in Water
doi 10.3389/frwa.2026.1874972
Original Research
Published
ALYREF regulates glycolysis and promotes the progression of endometrial cancer through m 5 C modification of PKM2 mRNA
Yun Feng · Xueyin Li
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1831562
Original Research
Published
Stage-specific transcriptional atlas of goose satellite cells uncovers sex-biased molecular dynamics associated with embryonic skeletal muscle development
Cui Wang · Kai Shi · Yi Liu · Yongping Yang · Guitao Jiang · Chuang Li · Shufang Chen · Huiying Wang · Daqian He
Frontiers in Cell and Developmental Biology
doi 10.3389/fcell.2026.1957937
Original Research
Published
Exploring the immune enhancement effect of radiotherapy combined with NK cells on non-small cell lung cancer based on proteomics technology
Cui Chang · Tang Youming · Lu Ying · Lei Ningning · Guo Chunhui · Wei Dekai · Liang Mei · Wu Qiyuan · Liu Gechen · Wu Fasheng · Chen Jibing
Oncology Reviews
doi 10.3389/or.2026.1853377
Original Research
Published
Isogenic human stem cell models reveal mutation-dependent protective mechanisms of APOE3 Christchurch
Carlye Frisch · Lauren Baker · Gayathri Srinivasan · Albert E. Mintah · Salma Leyasi · Morgan Pedroza · Brooke Galyon · David A. Brafman
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1856154
Hypothesis and Theory
Published
Harmonizing Vietnamese traditional and western medicine: a digital health blueprint and the IMKE architectural framework
Anh Nguyen Thi Dieu · Hieu Le Ngoc
Frontiers in Digital Health
doi 10.3389/fdgth.2026.1928965