Articles

Showing 106 articles

• Original Research

  Published 21 August 2026

  Breastmilk transfer and infant exposure to atazanavir/ritonavir in breastfeeding women with HIV: results from IMPAACT 2026

  Emily Anne Barr · Mauricio Pinilla · Jeremiah D. Momper · Ahizechukwu C. Eke · Lucy Koech · Kristina M. Brooks · Victoria Ndyanabangi · Sandra K. Burchett · Sujith Valiyaparambil · Mark Mirochnick · Alice Marie Stek · Brookie M. Best · Rachael Jeffrey · Chelsea Stotz · Marije Van Schalkwyk · Renee Browning · David E. Shapiro · Kathleen M. Powis

  Frontiers in Reproductive Health

  doi 10.3389/frph.2026.1892081

• Mini Review

  Published 20 August 2026

  3D- and 4D-printed scaffolds for osteoporotic bone regeneration: translational insights from in vivo preclinical and human-oriented studies

  Miguel Castro-Rodríguez · Luis Diaz-Gomez · Yolanda Sanz · Carmen Alvarez-Lorenzo · María Vallet-Regí

  Frontiers in Biomaterials Science

  doi 10.3389/fbiom.2026.1937864

• Original Research

  Published 20 August 2026

  New mechanistic insight into SARM1 activation: TRIM32-mediated ubiquitination is a key lever that actuates SARM1’s catalytic action, leading to axon degeneration and cell death

  Hitoshi Murata · Nahoko Tomonobu · Ken-ichi Yamamoto · Rie Kinoshita · Masakiyo Sakaguchi

  Frontiers in Neural Circuits

  doi 10.3389/fncir.2026.1842408

• Editorial

  Published 18 August 2026

  Editorial: Targeting cancer metabolic reprogramming for cancer therapy

  Werner J. Geldenhuys · Haitao M. Ji · Hoang V. Le

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1916506

• Brief Research Report

  Published 17 August 2026

  Navigating imaging artifacts: challenges with visualizing intrinsically fluorescent antimalarials

  Emily K. Bremers · David Anaguano · Paul R. Carlier · Vasant Muralidharan · Maria Belen Cassera

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1919904

• Review

  Published 14 August 2026

  Unlocking the opportunities and challenges of green strategies for bioavailability enhancement of polyphenols

  Arya Ojha · Sweta Acharya · Adarsh Sharma · Vivek S. S. Chougule · Nishi Mody · Ankit Jain

  Frontiers in Food Science and Technology

  doi 10.3389/frfst.2026.1911918

• Perspective

  Published 12 August 2026

  Antibiogram of pathogenic bacterial isolates from various samples in Prince Sultan Hospital, Western Region, Saudi Arabia. Retrospective study from 2020 to 2024

  Ebtehal H. Alqurashi · Najla A. Obaid · Alyaa Alzahrani · Fahad S. Alshareef · Najlaa M. Mohandes · Areej M. Althyabi · Sahar Albugami · Sultan Almammari

  Frontiers in Antibiotics

  doi 10.3389/frabi.2026.1872911

• Review

  Published 7 August 2026

  Gut microbiota-mediated biotransformation of dietary bioactive compounds: inter-individual variability, determinants, and implications for personalised nutrition

  Tapash Chakraborty · Shashanka Jyoti Kashyap · Pragyan Deep Chetia · Sumona Purkayastha

  Frontiers in Systems Biology

  doi 10.3389/fsysb.2026.1898890

• Original Research

  Published 6 August 2026

  Adjunctive antimycobacterial and immunomodulatory effects of Allium cepa (pink variety) in a rabbit model of latent-like mycobacterial infection

  Theophilus Kwesi Ninkyi · Eric Ogyam · Kelvin Atta Agyapong · Cynthia Amaning Danquah

  Frontiers in Tuberculosis

  doi 10.3389/ftubr.2026.1874315

• Review

  Published 4 August 2026

  Beyond the hallmarks of cancer: enabling technologies reshaping cancer diagnosis, prevention, and treatment

  Sarfaraz K. Niazi

  Oncology Reviews

  doi 10.3389/or.2026.1804447

• Review

  Published 30 July 2026

  Beyond one drug–one target: AI-guided discovery of multi-target antiviral therapeutics

  Vrinda Gupta · Sahil Sharma · Vikrant Abbot · Rohit Bhatia · Neeraj Choudhary · Dinesh Kumar

  Frontiers in Virology

  doi 10.3389/fviro.2026.1853552

• Review

  Published 28 July 2026

  Phytochemical interventions in bacterial resistance: plant metabolites as next-generation antibacterial agents

  Amin Mahmood Thawabteh · Anwar Ma’ali · Waed Ibdah · Donia Karaman · Rafik Karaman

  Frontiers in Chemical Biology

  doi 10.3389/fchbi.2026.1760834

• Editorial

  Published 24 July 2026

  Editorial: Structural and functional roles of membrane transport proteins in cellular physiology

  Olga Vinogradova

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1926644

• Original Research

  Published 14 July 2026

  In silico identification of organosulfur compounds from Allium ascalonicum L. as potential inhibitors of influenza A (H5N1): integrated DFT, docking, and molecular dynamics analysis

  Rangga Adhi Prastika · Alifaghi Pahlevi Ervianto Putra · Muhammad Alesha Fadhana · Volta Kellik Setiawan · Moh. Royhan Afnani · Sukma Sahadewa · Fara Disa Durry · Aswin Rafif Khairullah · I Made Dwi Mertha Adnyana · Abhishek Singh · Maksim Rebezov · Abdugani Abdurasulov · Vikash Jakhmola · Nitin Sharma · Nadezhda V. Kupaeva · Imam Siswanto · Arif Nur Muhammad Ansori · Arli Aditya Parikesit

  Frontiers in Virology

  doi 10.3389/fviro.2026.1857484

• Review

  Published 6 July 2026

  Physical feasibility gating in early drug discovery: a decision framework for identifying predictable physical failures, with retrospective illustration

  Sarfaraz K. Niazi

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1799663

• Original Research

  Published 3 July 2026

  Hematocrit-adjusted tacrolimus levels are associated with acute kidney injury but not rejection early after liver transplantation

  Trana Hussaini · Daljeet Chahal · Vladimir Marquez · Tianyi Wen · Monica Dahiya · Eric M. Yoshida · Michael R. Law

  Frontiers in Transplantation

  doi 10.3389/frtra.2026.1878595

• Editorial

  Published 30 June 2026

  Editorial: Pharmaceutical care and wellness of diabetes

  Havagiray R. Chitme · Mirza Muhammad Faran Ashraf Baig · Ajay Kumar Gupta

  Frontiers in Clinical Diabetes and Healthcare

  doi 10.3389/fcdhc.2026.1910046

• Editorial

  Published 29 June 2026

  Editorial: Accelerating antibiotic development from natural products: tackling antimicrobial resistance (AMR)

  Sanjib Bhakta · Cynthia Amaning Danquah · RuAngelie Edrada-Ebel · Simon Gibbons

  Frontiers in Antibiotics

  doi 10.3389/frabi.2026.1898318

• Review

  Published 29 June 2026

  The nano-neuro nexus: smart sensors at the frontier of detecting neurodegeneration

  Arpit Mehrotra · Abhilasha Sood · Shraddha Yadav · Aditi D. Raval · S. Renuka Jyothi · Ashok Kumar Sah · Chandan Sharma · Laxmidhar Maharana

  Frontiers in Nanotechnology

  doi 10.3389/fnano.2026.1843615

• Review

  Published 16 June 2026

  Use of public health databases for the early identification of Autism spectrum disorder: a scoping review protocol

  Luiz Jupiter Carneiro de Souza · Luis Phillipe Nagem Lopes · Mariana Del Grossi Moura · Katia Miyuki Sasaki Zeredo · José Fernando Salvador Carrillo · Joaquim Lucas Júnior · Mabel Fernandes Figueiró · Jose Antonio Silvestre Fernandes Neto · Luciane Cruz Lopes · Waldecy Rodrigues

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2026.1816967

• Brief Research Report

  Published 12 June 2026

  Anti-leishmanial activity and dereplication using GC-MS assisted by molecular networking of the essential oil from the leaves and inflorescence of Melaleuca viminalis (myrtaceae)

  Ana Clara L. N. Silva · Marisi G. Soares · Eduard Choi Jr. · Gabriela V. Araujo Flores · Luiz Felipe D. Passero · Márcia D. Laurenti · Patrícia Sartorelli

  Frontiers in Natural Products

  doi 10.3389/fntpr.2026.1826685

• Case Report

  Published 14 May 2026

  Spine-centred integrated osteopathic management for multi-site degenerative musculoskeletal pain after conventional and traditional healing failure in a low-resource setting: a concept-driven case report

  Ibrahim Npochinto Moumeni

  Frontiers in Musculoskeletal Disorders

  doi 10.3389/fmscd.2026.1811905

• Review

  Published 12 May 2026

  Variability in the circulation of cerebrospinal fluid: causes and clinical implications for intraventricular drug delivery

  Herbert H. Engelhard · Olivier Balédent · Matthew T. Borzage · Lydia Andrews-Jones · Thomas M. Feldsien · Didier R. Lefebvre

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1735474

• Perspective

  Published 8 May 2026

  Challenges in drug efficacy and toxicity screening with 3D bioprinted melanoma models

  Lissinda H. du Plessis · Nonzuzo Myeza · Chrisna Gouws · Awie F. Kotzé · Daniel Nieto

  Frontiers in Cell Death

  doi 10.3389/fceld.2026.1821035

• Editorial

  Published 5 May 2026

  Editorial: Targeted cancer therapy through metabolic pathways

  Prasanna Srinivasan Ramalingam · Md Sadique Hussain · Shreyas Ramchandra Gaikwad · Sivakumar Arumugam

  Frontiers in Molecular Medicine

  doi 10.3389/fmmed.2026.1842647

• Review

  Published 4 May 2026

  Oral delivery of biologics: from barrier-limited formulation to active convective transport

  Sarfaraz K. Niazi

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1783113

• Review

  Published 30 April 2026

  From biosimilars to breakthroughs: regulatory convergence toward evidence-efficient development of monoclonal antibodies

  Sarfaraz K. Niazi

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1778468

• Original Research

  Published 29 April 2026

  Radiopharmacy services in South African academic hospitals: implications for planning radiopharmacy services in Africa

  David Kimani · Beverley Summers · Lerato Mosima

  Frontiers in Nuclear Medicine

  doi 10.3389/fnume.2026.1822893

• Mini Review

  Published 22 April 2026

  Training the next-generation of biomedical scientists through artificial intelligence-driven education and research in pharmacology and pharmaceutical sciences

  Santosh Kumar · Ritu Karwasra · Weinan Zhou · Jayaraman Seetharaman · Bhupesh Singla

  Experimental Biology and Medicine

  doi 10.3389/ebm.2026.10988

• Editorial

  Published 21 April 2026

  Editorial: SARS-CoV-2: virology, epidemiology, diagnosis, pathogenesis and control, volume II

  Severino Jefferson Ribeiro da Silva · Larissa Krokovsky · Ronaldo Celerino da Silva · Zhen Qin

  Frontiers in Virology

  doi 10.3389/fviro.2026.1838913

• Original Research

  Published 10 April 2026

  Molecular taxonomic characterisation of Ancylostoma spp. and Strongyloides spp. in three protected areas in Ghana

  Sandra S. Gyarteng Mensah · John Asiedu Larbi · Adrian Streit

  Frontiers in Parasitology

  doi 10.3389/fpara.2026.1798958

• Review

  Published 10 April 2026

  Beyond GLP-1: underexplored peptide–receptor systems as the next frontier in drug discovery

  Sarfaraz K. Niazi

  Frontiers in Drug Discovery

  doi 10.3389/fddsv.2026.1792418

• Original Research

  Published 26 March 2026

  Dose optimization of inhaled tigecycline in humans to overcome inherent adverse events and maximize bacterial clearance using a physiologically-based pharmacokinetic modeling approach

  Hyunseo Park · Amarinder Singh · Ashish Srivastava · Bhargavi Thalluri · Christelle J. Mathieu · Paridhi Gupta · Camron M. Pearce · Malik Zohaib Ali · Ilham M. Alshiraihi · Sara E. Maloney Norcross · Anthony J. Hickey · Mercedes Gonzalez-Juarrero · Bernd Meibohm

  Frontiers in Tuberculosis

  doi 10.3389/ftubr.2026.1762713

• Original Research

  Published 12 March 2026

  Low dose thirdhand smoke exposure enhances platelet functional responses in mice

  Precious O. Badejo · Ahmed B. Alarabi · Hamdy E. A. Ali · Lanam Millican · Reina De La Paz · Shelby S. Umphres · Sadia Kamal · Fatima Z. Alshbool · Fadi T. Khasawneh

  Experimental Biology and Medicine

  doi 10.3389/ebm.2026.10679

• Review

  Published 9 March 2026

  IDRs in Cross-Membrane Transport: Regulation of Ion Channels and Transporters, Mechanistic Studies Made Possible by NMR and Computational Methods

  Olga Vinogradova

  Frontiers in Biophysics

  doi 10.3389/frbis.2026.1804302

• Original Research

  Published 13 February 2026

  Colour of medicines and children’s acceptability: What children think of the colour of oral dosage forms?

  Elisa Alessandrini · Sveinbjorn Gizurarson · Jennifer Walsh · Roy Turner · Daniel Schaufelberger · Sonia Iurian · Hannah Batchelor · Sandra Klein · Begonya Nafria · Pamela Dicks · Segolene Gaillard · Axel R. Franz · Jasmin Albano · Aleksander Wisniewski · Charlotte Vermehren · Christina Gade · Jon Traerup Andersen · Catherine Tuleu

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2026.1744120

• Original Research

  Published 11 February 2026

  Chronic low back pain management in rural Cameroon: a pragmatic pilot study of osteopathic care, physiotherapy, and the “unique practitioner syndrome”

  Ibrahim Npochinto Moumeni · Abdel-Nasser Njikam Moumeni · Tchuidjio Ketchogue Bristher Orlsiter · Fausting Atemkeng-Tsatedem

  Frontiers in Musculoskeletal Disorders

  doi 10.3389/fmscd.2025.1716794

• Original Research

  Published 3 February 2026

  The use of QbD for the development and validation of a stability-indicating RP-HPLC method for the quantitation of nevirapine in bulk, tablet and niosome formulations

  Bwalya A. Witika · Roderick B. Walker

  Frontiers in Analytical Science

  doi 10.3389/frans.2026.1735125

• Review

  Published 28 January 2026

  Current status of antimicrobial resistance in Indian healthcare system: combating antimicrobial resistance with precision medicine

  Ashish Shinde · Athira Mohan · Vani Mahathi Bulusu · Poonam Soni · Jitendra Singh · Sagar Khadanga · Ankur Joshi · Poongothai Venkatachalapathy · Rupinder Kaur Kanwar · Sonal Sekhar Miraj · Murali Munisamy

  Frontiers in Antibiotics

  doi 10.3389/frabi.2026.1632790

• Original Research

  Published 20 January 2026

  Morphological and transcriptomic change of brain pericytes by lipopolysaccharide treatment

  Taiki Asai · Yoshino Yonezu · Akiko Uyeda · Haruki Watanabe · Tatsunori Suzuki · Hidemi Misawa · Rieko Muramatsu

  Frontiers in Neural Circuits

  doi 10.3389/fncir.2026.1725431

• Original Research

  Published 12 January 2026

  Development of a comprehensive approach for the characterization of polar plant decoctions by orthogonal LC-MS reversed phase, HILIC, and NMR metabolite profiling: the case of Combretum micranthum

  Lisa Vuadens · Robin Huber · Laurence Marcourt · Luis-Manuel Quiros-Guerrero · Olivier Auguste Kirchhoffer · Arnaud Gaudry · Renata Campos Nogueira · Elhadji Assane Diop · Sidi Mohamed Seck · Jean-Luc Wolfender · Emerson Ferreira Queiroz

  Frontiers in Natural Products

  doi 10.3389/fntpr.2025.1717575

• Perspective

  Published 6 January 2026

  Enabling living in space through modern innovations in space medicine: a perspective on tissue-on-a-chip technology

  Subhajit Hazra · Sibsankar Palit · Thais Russomano · Gaurab Ghosh · Polash Sannigrahi

  Frontiers in Space Technologies

  doi 10.3389/frspt.2025.1725575

• Original Research

  Published 2 January 2026

  Radiolabeled para -I-nimesulide: an unexpected tracer for imaging peripheral inflammation

  Yumi Yamamoto · Kentaro Imai · Yohei Saito · Fumihiko Yamamoto

  Frontiers in Nuclear Medicine

  doi 10.3389/fnume.2025.1720380

• Original Research

  Published 29 December 2025

  Cohort event monitoring of booster COVID-19 vaccine safety using patient-reported outcomes in pregnant women

  Emeline Maisonneuve · Nicoletta Luxi · Chiara Bellitto · Francesco Ciccimarra · Monika Raethke · Florence van Hunsel · Thomas Lieber · Erik Mulder · Fabio Riefolo · Felipe Villalobos · Nicolas H. Thurin · Francisco Batel-Marques · Kathryn Morton · Fergal O'Shaughnessy · Brian Cleary · Simona Sonderlichová · Andreea Farcas · Camelia Bucsa · Guillaume Favre · Satu J. Siiskonen · David Baud · Miriam C. J. M. Sturkenboom · Gianluca Trifirò · Alice Panchaud

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2025.1689349

• Review

  Published 17 December 2025

  Pharmacovigilance and bioethics: the importance of a neglected relationship

  Giuseppe Alvaro · Michael Müller · Richa Chhibber · Robert Fuentes

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2025.1698515

• Original Research

  Published 12 December 2025

  Mechanics-guided parametric modeling of intranasal spray devices and formulations for targeted drug delivery to the nasopharynx

  Md Tariqul Hossain · Abir Malakar · Mohammad Yeasin · William O’Connell · Mohammad Mehedi Hasan Akash · Azadeh A. T. Borojeni · Devranjan Samanta · Gerallt Williams · Joshua Reineke · Gonçalo Farias · Sunghwan Jung · Julie Suman · Saikat Basu

  Frontiers in Drug Delivery

  doi 10.3389/fddev.2025.1721960

• Review

  Published 26 November 2025

  Discrepancies in regulations in post-marketing safety surveillance of drug-device combination products in the EU and US: a review

  Joan D’souza · Mukesh Nandave · Ruth Blöchlinger

  Frontiers in Drug Safety and Regulation

  doi 10.3389/fdsfr.2025.1609455

• Brief Research Report

  Published 20 November 2025

  First positronium lifetime imaging with scandium-44 on a long axial field-of-view PET/CT

  Lorenzo Mercolli · William M. Steinberger · Pascal V. Grundler · Anzhelika Moiseeva · Saverio Braccini · Maurizio Conti · Paweł Moskal · Narendra Rathod · Axel Rominger · Hasan Sari · Roger Schibli · Robert Seifert · Kuangyu Shi · Ewa Ł. Stepień · Nicholas P. van der Meulen

  Frontiers in Nuclear Medicine

  doi 10.3389/fnume.2025.1648621