Review
Published
Aging, the microbiota–gut–brain axis, and late-life epilepsy: a hypothesis-driven review
Yingsi Cao · Huiying Li · Minzheng Xu · Yuting Teng
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1861519
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Showing 191 articles
Review
Published
Analysis of the heterogeneity of the immune microenvironment of bone metastases and new strategies of nanotechnology intervention
Chenyang Wu · Xueli Qiu · Chao Wang · Jinyu Bai · Xiaozhong Zhou
Oncology Reviews
doi 10.3389/or.2026.1820639
Review
Published
Copper-regulated cell death after spinal cord injury: evidence boundaries for non-coding RNA, epigenetics and cuproptosis
Jun Tao · Guobing Wang · Guoying Jiang · Wenqi Feng
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1885261
Original Research
Published
In silico transcriptomic analysis nominates TSPAN32 as a central node of SCFA-driven immunometabolic reprogramming in intestinal epithelial cells
Zahra Masood · Iqra Sarwar · Ayesha Sanam · Amber Zaidi · Muhammad Zulfiqah Sadikan
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1847552
Original Research
Published
Diversity of glutamate receptors in glial cells of the mouse optic nerve
Nine F. Kompier · Marcus Semtner · Sophie Walter · Christian Steinhäuser · Christiane Nolte · Helmut Kettenmann
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1911068
Original Research
Published
Genome-wide identification and evolutionary characterization of predicted HSP70 proteins in the Cuban painted snail Polymita picta
Mario Juan Gordillo-Pérez · Bernardo Reyes-Tur · Zeyuan Chen · Julia Sigwart · Carola Greve · Martijn Heleven · Karen Smeets · Natalie Beenaerts
Frontiers in Ecology and Evolution
doi 10.3389/fevo.2026.1933916
Mini Review
Published
At the nucleus of neuronal health: Drosophila insights into LaminB-dependent homeostasis in aging and cell death
Francesco Napoletano
Frontiers in Cell Death
doi 10.3389/fceld.2026.1954383
Original Research
Published
Physiological and redox status properties of a new late-ripening triploid hybrid mandarin: a seasonal field evaluation
Benoit Allegrini · Livia-Maria Venturini · Julie Oustric · Laurent Julhia · Yann Froelicher · Liliane Berti · Radia Lourkisti · Jérémie Santini
Frontiers in Plant Physiology
doi 10.3389/fphgy.2026.1896981
Original Research
Published
Structural and functional defects of mitochondrial serine hydroxymethyltransferase genetic variants responsible for a novel neurodevelopmental syndrome
Giovanna Boumis · Sara Breccia · Gianluca Pistoia · Sharon Spizzichino · Carlotta Zamparelli · Francesca Troilo · Adele Di Matteo · Carlo Travaglini Allocatelli · Roberto Contestabile · Angela Tramonti · Francesca Cutruzzolà · Giorgio Giardina
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1941005
Original Research
Published
Integrative genome-scale metabolic model of GABAergic neurons reveals metabolic signatures across the mild cognitive impairment – Alzheimer disease continuum
Andrea Angarita-Rodríguez · Johan H. Largo-González · Julián Pérez-Mejía · Daniel Balcazar · Viviana Vargas-López · Jason A. Papin · Andrés Pinzón · Janneth González
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1897648
Review
Published
Lipid metabolic reprogramming in clear cell renal cell carcinoma: focus on high-density lipoprotein-related pathways
Lize Wu · Huaying Xue · Yifei Wu · Ningning Shen · Zhiqing Yang · Lifang Gao · Wenxia Ma · Chen Wang
Oncology Reviews
doi 10.3389/or.2026.1887460
Original Research
Published
Primary cell and tissue cultures of human choroid plexus epithelial cells
Ronja Bihlmaier · Melanie Scharr · Peter H. Neckel · Bernhard Hirt · Andreas F. Mack
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1827493
Original Research
Published
Polymer-specific nanoplastics trigger oxidative stress, inflammatory activation, and mitoepigenetic remodeling: in vitro and in silico evidence for MT-ND6-mediated mitochondrial complex I perturbation
Pradyumna Kumar Mishra · Aneha K. Rajan · Apoorva Chouksey · Vikas Gurjar · Ashwani Pathak · Aniket Aglawe · Ravi Prakash Tiwari · Debabrata Dash · Ram Kumar Nema · Rajnarayan Tiwari · Devojit Kumar Sarma · Rupesh K. Srivastava
Frontiers in Toxicology
doi 10.3389/ftox.2026.1916884
Mini Review
Published
Microgravity- induced organ and system-level deconditioning: a network physiology perspective
Rashmi Neginhal · Rebecca Rejo George
Frontiers in Network Physiology
doi 10.3389/fnetp.2026.1931834
Perspective
Published
Set-point shifts in peri-anesthetic fluid homeostasis: a conceptual framework informed by α 2-agonist diuresis
Shotaro Nagahama
Frontiers in Anesthesiology
doi 10.3389/fanes.2026.1873909
Original Research
Published
Molecular abnormalities scale across three models of cerebral injury
Volha Liaudanskaya · Matthew J. Robson · Nicole L. Vike · Sumra Bari · Christopher J. O’Connell · Orlando S. Hoilett · David L. Kaplan · Thomas M. Talavage · Eric A. Nauman · Semyon Slobounov · Hans C. Breiter
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1844343
Review
Published
Mitochondrial control of blood-brain barrier homeostasis in neuroinflammatory psychiatric disorders
Larli Misael Pérez-López · Alberto Camacho-Morales · Ivón Howland-Álvarez · Antonio Alí Pérez-Maya
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1924581
Original Research
Published
Rotenone-induced oxidative stress triggers peroxisomal alterations in BV-2 microglial cells
Alessio Valenza · Maurizio Muzzi · Francesca Rendina · Irene Montali · Daniele Pensabene · Anna Fracassi · Marco Segatto · Sandra Moreno
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1941513
Review
Published
From metabolism to neurodegeneration: how microglial functional reprogramming drives neurodegenerative diseases
Qiaoqiao Cui · Ke Zheng · Qiyun Liu · Lizhen Wang · Yixin Liu · Ruifang Bai · Wei Zhang · Junhong Guo · Xueli Chang · Juan Wang
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1921079
Review
Published
Aquaporin dysfunction and impaired brain interstitial fluid clearance in Alzheimer’s disease – an integrative review
Marina Daniela Manescu · Teodora Minca · Ionica Pirici · Cristina Jana Busuioc · Valentin Octavian Mateescu · Daniel Pirici
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1903812
Review
Published
Mesenchymal stem cell senescence as a potency brake: causes, consequences, and cures
Sen Zhou · Yu Xie · Yanjie Guo · Yufu Zhang · Yusi Liu
Frontiers in Aging
doi 10.3389/fragi.2026.1929624
Review
Published
Silent Kv subunits as major players in cell membrane excitability
Mohammed Alshemery · Mert Beyazyildirim · Joao L. Carvalho-de-Souza
Frontiers in Biophysics
doi 10.3389/frbis.2026.1925801
Brief Research Report
Published
Bone morphogenetic protein 4-associated mitochondrial dysfunction in diabetic nephropathy involves Parkin downregulation
Masanori Tamaki · Tatsuya Tominaga · Kazuhiro Hasegawa · Takahiro Kida · Shinji Miyakami · Ikuko Shimizu · Sumiyo Yamaguchi · Masanori Minato · Kojiro Nagai · Shu Wakino
Frontiers in Clinical Diabetes and Healthcare
doi 10.3389/fcdhc.2026.1860424
Review
Published
FcεRII (CD23) in dermatological disorders: structure, function, and clinical implications
Natalia Zdanowska · Wiktoria Nowik-Zając · Joanna Czerwińska · Joanna Najbar · Agnieszka Owczarczyk-Saczonek
Frontiers in Allergy
doi 10.3389/falgy.2026.1849342
Review
Published
Regulated cell death in the nervous system: a framework for execution diversity and spatially restricted degeneration
Laura Lossi · Marco Sbriz · Claudia Castagna · Adalberto Merighi
Frontiers in Cell Death
doi 10.3389/fceld.2026.1823132
Review
Published
Gut microecology in critical illness: mechanisms, biomarkers, and therapeutic strategies — a critical appraisal
Liang Tian · Shanshan Xu · Xueping Xie · Man Wang · Lina Huang
Frontiers in Gastroenterology
doi 10.3389/fgstr.2026.1902608
Mini Review
Published
Trehalose metabolism: an integrative hub linking energy homeostasis and development in insects
Sharada D. Mohite · Rakesh S. Joshi
Frontiers in Insect Science
doi 10.3389/finsc.2026.1872741
Review
Published
Functional genetic signatures of the gut microbiome in cardiometabolic diseases: mechanisms and translational opportunities
Martin Nganga Muigano
Frontiers in Microbiomes
doi 10.3389/frmbi.2026.1847345
Original Research
Published
Hydrogen peroxide as a multifaceted regulator of the Atg4 protease and autophagy in the pathogenic fungus Alternaria alternata
Hsin-Yu Lu · Je-Jia Wu · Celine Yen Ling Choo · Pei-Ching Wu · Kuang-Ren Chung
Frontiers in Fungal Biology
doi 10.3389/ffunb.2026.1881957
Systematic Review
Published
Nucleus accumbens GLP-1 signaling and its role in reward and metabolic regulation: a systematic review
Maysa Edwiges · Susana I. Sá · Rui Lopes · Cesar Portela · José Paulo Andrade · João Rocha-Neves
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1880560
Systematic Review
Published
Global research landscape and trends of metabolomics in diabetic kidney disease: focus on immunometabolic interactions
Yuting Li · Changlin Li · Jiamin Duan · Qingli Yang · Jing Zhang · Duo Yu · Yuwei Chen · Jianing Ni · Xiaomeng Lin · Xudong Cai
Frontiers in Clinical Diabetes and Healthcare
doi 10.3389/fcdhc.2026.1791774
Frontiers in Science Lead Article
Published
The glucose ketone index: a proposed quantitative biomarker to support cancer and chronic disease prevention and management
Derek C. Lee · Tomas Duraj · Isabella D. Cooper · Joseph C. Maroon · Kris Smith · Wafaa Abdel-Hadi · Egiroh Omene · Athanasios E. Evangeliou · Thomas N. Seyfried
Frontiers in Science
doi 10.3389/fsci.2026.1763395
Hypothesis and Theory
Published
Neuroinflammation as a failure of allostatic integrity: a hierarchical-circular model of biological memory for pathogenesis in neurodegenerative and neuropsychiatric diseases
Samuel Ruesga Mundo
Frontiers in Systems Neuroscience
doi 10.3389/fnsys.2026.1888548
Review
Published
Obesity from the perspective of the liver
Miklós Csala · József Mandl
Pathology and Oncology Research
doi 10.3389/pore.2026.1612376
Original Research
Published
The AcasR-FadD9 regulatory axis modulates iron homeostasis and susceptibility to the anti-mycobacterial compound ACA
Feng Huang · Zixin Wang · Dong Jiang · Shengyi Li · Zheng-Guo He · Hua Zhang
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1830528
Mini Review
Published
Mitochondrial transfer and mesenchymal stem cells in ophthalmology: current evidence and therapeutic implications
Xiaoli Liu · Mingqi Zhang · Zhuoshi Wang
Experimental Biology and Medicine
doi 10.3389/ebm.2026.11128
Original Research
Published
Influence of the pyruvate kinase activator mitapivat (AG-348) on RBC ATP content and export and RBC adhesivity in blood from healthy subjects and sickle cell disease patients
Apoorva Jagadish · Youwei Chen · Hongmei Zhu · Weijia Mai · Shein-Chung Chow · Zhong Li · Grace M. Lee · Marilyn J. Telen · Tim J. McMahon
Frontiers in Hematology
doi 10.3389/frhem.2026.1766692
Mini Review
Published
How do pro-inflammatory cytokines alter miRNA profiles in brain endothelial cells? Mechanisms, consequences, and therapeutic strategies for blood-brain barrier protection
Nahla Galal Metwally · Sara Mohamad · Iris Bruchhaus
Frontiers in Malaria
doi 10.3389/fmala.2026.1849845
Frontiers in Science Lead Article
Published
Regulatory T cells: master orchestrators of immune tolerance and tissue homeostasis
Jeffrey A. Bluestone · Megan K. Levings · Frederick J. Ramsdell · Alexander Y. Rudensky · Qizhi Tang · Piotr Trzonkowski
Frontiers in Science
doi 10.3389/fsci.2026.1792210
Methods
Published
Engineering Mycobacterium smegmatis to produce oxygenic mycolic acids of Mycobacterium tuberculosis
Udipta Bohara · Liwu Li · Biswarup Mukhopadhyay · Endang Purwantini
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1809486
Review
Published
Mechanistic insights into the synaptic damage-repair and regeneration processes in neurodegenerative Alzheimer’s disease: phytochemicals as neuroprotective agents
Bharti Yadav · Prabhakar Gangwar · Kirti Kumari · Anuradha Yadav · Rashmi Rao · Keshav Kumar · Harkomal Verma · Monisha Dhiman · Anil Kumar Mantha
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1835778
Review
Published
Zinc-binding proteins in Alzheimer’s disease: mechanisms, therapeutic potential, and natural compound interventions
Riddhi Upadhyay · Susmita Kar · Murugan Sevanan
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1836070
Review
Published
Exploring the gut–brain axis: dietary influences on Alzheimer’s disease pathogenesis
Samira R. Mansour · Menna A. Khalaf · Mostafa A. Moustafa · Mardies A. Moustafa · AbdelRaouf A. Moustafa
Frontiers in Microbiomes
doi 10.3389/frmbi.2026.1639904
Review
Published
Integrative perspectives on electroacupuncture modulation of vagal–cholinergic and neuro–immune–metabolic regulation in long COVID
Liwen Wang · Xiaoyang Hu · Dongning Yan
Frontiers in Integrative Neuroscience
doi 10.3389/fnint.2026.1775007
Review
Published
The interplay between bile acid metabolism and gut microbiome in biliary tract cancers
Ifeoma Ike · Farzad Teymouri · Christiana Crook · Sofia Guzman · Max Hazeltine · Dani Castillo · Daneng Li · Gagandeep Brar
Frontiers in Microbiomes
doi 10.3389/frmbi.2026.1774429
Review
Published
Engineering yeast for sustainable production of sterols, steroids, and bile acids: advances, strategies, and future directions
Hee Yeon Song · Ga Won Lee · Young Hoon Jung · Jae Won Lee
Frontiers in Chemical Engineering
doi 10.3389/fceng.2026.1833599
Original Research
Published
Psychophysiological effects of low-frequency sound mediated by room size, room shape, and stimulus duration
Paul Oomen · Rona Geffen · Daniela Gentile · Nour Atassi · Bashar Farran · Christoph Braun · Veronica Cuevas Villanueva · Luka Nadiradze · Máté Csanád · Amira Val Baker
Frontiers in Cognition
doi 10.3389/fcogn.2026.1806052
Review
Published
Variability in the circulation of cerebrospinal fluid: causes and clinical implications for intraventricular drug delivery
Herbert H. Engelhard · Olivier Balédent · Matthew T. Borzage · Lydia Andrews-Jones · Thomas M. Feldsien · Didier R. Lefebvre
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1735474