Hypothesis and Theory
Published
Economic impact of biomarker-based aging interventions on healthcare costs and individual value
Federico Felizzi
Frontiers in Genetics
doi 10.3389/fgene.2026.1814599
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 2614 articles
Original Research
Published
Cross-lineage anomaly detection of microRNA expression: a framework for deriving exploratory candidate biomarkers in sarcoma
Mritunjoy Dey · Piotr Remiszewski · Ewelina Perdas · Paweł Golik · Jakub Piątkowski · Anna M. Czarnecka
Frontiers in Genetics
doi 10.3389/fgene.2026.1907450
Original Research
Published
Different stimulation methods for the rat treadmill exercise model used in cardiovascular disease research
Yu Jiang · Lihua Fang · Jingwen Xiao · Qinfei Wei · Xiaona Lin · Yan Zhang
Frontiers in Physiology
doi 10.3389/fphys.2026.1905960
Review
Published
Flavonoids in cancer pharmacology: molecular mechanisms, tumor microenvironment regulation, and drug resistance
Zhengyuan Yu · Zhanyi Zhou · Ni Yin · Hongcheng Ge
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1969337
Original Research
Published
Fibrinolytic suppression and increased uterine artery resistance are associated with embryo resorption in DBA/2 mated CBA/J mice
Youchen Liu · Jingjing Wang · Boning Huang · Ping Tang · Fangle Liu · Yuying Zheng · Yilin Li · Huiyi Xie · Liuqing Lin · Xinrong Yang · Xiubing Zhang · Jie Gao · Baoqin Lin
Frontiers in Physiology
doi 10.3389/fphys.2026.1942168
Original Research
Published
New software for assessment and interpretation of pulmonary function tests in adults: a comparative validation study
Khadija Ayed · Mhamed Acheche · Juan Del Coso · Ismail Laher · Ayoub Saeidi · Anthony C. Hackney · Hassane Zouhal
Frontiers in Physiology
doi 10.3389/fphys.2026.1917497
Review
Published
Early life stress, lower urinary tract dysfunction, and respiratory disease: a proposed shared-mechanism framework
Tadanobu Chuyo Kamijo · Mayoko Tsuji
Frontiers in Physiology
doi 10.3389/fphys.2026.1929695
Review
Published
High-altitude gastric disorders: insights into maladaptation pathophysiological mechanisms, disease spectrum and prevention strategies
Huihui Shang · Rong Zhang · Youbang Xie · Airong Yang · Jing Wang
Frontiers in Physiology
doi 10.3389/fphys.2026.1944395
Original Research
Published
Agreement between upper-arm and wrist cuff occlusion for the assessment of vascular reactivity by digital thermal monitoring
Hamidreza Mohammadi · Ali Hashemi · Timothy O’Brien · Hamed Ghoshouni · Hirofumi Tanaka · Robert A. Kloner · Morteza Naghavi
Frontiers in Physiology
doi 10.3389/fphys.2026.1961953
Original Research
Published
Taxifolin alleviates podocyte injury and macrophage chemotaxis associated with diabetic nephropathy by directly targeting RBP1 identified via multi-omics and machine learning
Zi-Xuan Wang · Wen-Xuan Wang · Qiong-Dan Liang · Ling-Dong Kong
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1933167
Original Research
Published
Physiologically-based pharmacokinetic model to predict pharmacokinetics of KY0467 in humans and guide dose selection in infants and children
Panpan Xie · Yanyan Yang · Xuemei He · Ming Yang · Zhixing Chen · Xi Weng · Aixin Shi
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1866331
Original Research
Published
Electroacupuncture pretreatment attenuates myocardial ischemia/reperfusion injury-induced ferroptosis via the p53/SLC7A11/GPX4 pathway
Jing Mao · Qian-Ru Guo · Yi-Pu Luo · Cong-Fei Liu · Zhen-Yang Cao · Yun-Tao Yu · Wen-Wei Wu · Xin-Yu Luan · Dan-Ning Xu · Hua Wang · Pu Chen · Song Wu
Frontiers in Physiology
doi 10.3389/fphys.2026.1928208
Original Research
Published
Associations between spike velocity and physical characteristics in elite sitting volleyball players
Shaocheng Sun · Meiling Ren · Jinhu Yan
Frontiers in Physiology
doi 10.3389/fphys.2026.1992570
Original Research
Published
Whole-exome sequencing reveals cumulative rare variant burden associated with susceptibility to anti-tuberculosis drug-induced liver injury in a Han Chinese cohort
Yang Hao · Xiaoqing Zhang · Daiyun Huang · Shengyin Qin · Yunxiao Lin · Jianwen Ruan · Lu Shen · Na Zhang · Zhenting Wang · Cong Huai · Jianquan Zhang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1952049
Mini Review
Published
From emergency myelopoiesis to trained immunity? Reframing post-stroke myeloid reprogramming along the brain-bone marrow axis
TongZhu Wei · YongJiu Wang
Frontiers in Neurology
doi 10.3389/fneur.2026.1976078
Original Research
Published
Clinical study of isokinetic training with joint control tasks on lower limb function in stroke patients with proprioceptive impairment: a preliminary randomized controlled trial
Zhendong Zhang · Huixian Yu · Ping Li · Na Li · Yumei Zhang
Frontiers in Neurology
doi 10.3389/fneur.2026.1881854
Perspective
Published
Precision targeting of type 2 inflammation in COPD: identifying candidates for dupilumab therapy
Kezhuo Zhong · Kaiying Lv · Qun Liang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1971309
Original Research
Published
Perception of virus effects and vaccination among people with multiple sclerosis in Saudi Arabia
Hind Alnajashi · Khadijah Ibraheem Basheikh · Bushra Obaidallah A. Alqurayqiri · Fayzah Shaikh Albar · Shahad Ayed M. Algarni · Lana Saeed Allakhmi
Frontiers in Neurology
doi 10.3389/fneur.2026.1816182
Review
Published
Clinical evaluation of visual snow syndrome: a structured narrative review with proposed clinical diagnostic approach
Nemira Žilinskaitė-Tranas · Gytis Makarevičius · Aušra Liveikienė · Kristina Ryliškienė
Frontiers in Neurology
doi 10.3389/fneur.2026.1961508
Systematic Review
Published
The application of square-stepping exercise in patients with stroke: a scoping review
Yali Yan · Juan Xu · Jiaxin Yao · Yuanyuan Liu · Mengdan Li · Xinxin Geng
Frontiers in Neurology
doi 10.3389/fneur.2026.1952887
Systematic Review
Published
Procedural interventions for chronic migraine: an umbrella review intervention-specific evidence map
Lijie Xia · Dianhui Yang · Yan Lu · Yunfei Gong · Chengtao Zhang
Frontiers in Neurology
doi 10.3389/fneur.2026.1915292
Systematic Review
Published
Efficacy of digital interventions for patients with post-stroke aphasia: a systematic review and network meta-analysis
Junjie Shi · Yue Sun · Jingyi Zhang · Zeyu Yang · Jia Hu · Liang Zhi · Qingfang Zhang · Yulong Wang · Jianjun Long
Frontiers in Neurology
doi 10.3389/fneur.2026.1936067
Original Research
Published
Development and internal validation of a clinical prediction model for postoperative venous thromboembolism after neurosurgical intervention in patients with traumatic brain injury
Dongping Li · Jianhui Chen · Chunfa Weng · Jianhuang Huang
Frontiers in Neurology
doi 10.3389/fneur.2026.1953953
Mini Review
Published
Mapping the neural basis of the perception of “flow of time”: interval timing and mental time travel in the human brain
Ryuta Ochi · Mitsuru Kawamura
Frontiers in Neurology
doi 10.3389/fneur.2026.1960572
Systematic Review
Published
Prognostic value of multiple biomarkers for kidney function decline in type 2 diabetes with relatively preserved kidney function: a systematic review and exploratory meta-analysis
Jie Hu · Xinyu Pan · Shuwu Wei · Junping Wei
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1938521
Original Research
Published
Associations of the triglyceride-glucose index and intracranial arterial stenosis with poor functional outcome after ischemic stroke: a retrospective observational study of 712 patients
Baoyi Liao · Yongzhe Gu · Nuo Ma · Aiping Jin · Shengqi Yao
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1949849
Original Research
Published
Metformin and atorvastatin ameliorate MASH via the AMPK/NF-κB pathway
Bin Zhang · Na Li · Fang Liu · Guorui Wang · Quanwei Chen · Yiming Sun · Ni Yang · Hao Zhang · Jianjun Han
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1972846
Editorial
Published
Editorial: Current insights in sperm motility and male fertility
Gabriela R. Mendeluk · Nafisa H. Balasinor
Frontiers in Endocrinology
doi 10.3389/fendo.2026.2004991
Original Research
Published
Nonlinear relationship between serum LH levels on hCG trigger day and live birth rates in patients with fresh embryo transfer: a retrospective cohort study
Yue Zhang · Yuxuan Xiao · Aimin Yang · Yang Yang · Lei Jiang · Jiahua Zheng · Kaixuan Guo · Wei Wang
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1957191
Original Research
Published
Effectiveness and safety of imeglimin in routine clinical practice among Indian patients with type 2 diabetes mellitus: a prospective, non-interventional, real-world observational study (INDI-TIMES 2.0)
Debmalya Sanyal · Anuj Maheshwari · Subrata Chakrabarti · Manoj Chawla · Mangesh Tiwaskar · Soujanya Kunapa Reddy · S Sridhar · Arthur Joseph Ashirvatham · Rituraj Benode Deb · Gayathry V M
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1973270
Original Research
Published
Diagnostic delay length and disease severity are the main predictors of sleep apnea in acromegaly patients
Rosa Pirchio · Renata Simona Auriemma · Stefano Sanduzzi Zamparelli · Paola Bonavolontà · Claudia Merola · Angelo Canora · Claudia Pivonello · Alessandro Sanduzzi Zamparelli · Rosario Pivonello · Annamaria Colao
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1928818
Review
Published
Breakdown of adipocyte-endothelial communication as a driver of adipose tissue dysfunction in obesity
Vaishali Chaurasiya · Dan Duc Pham · Vesa M. Olkkonen
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1957205
Original Research
Published
Long-term post-trial extension of osilodrostat therapy in selected Canadian patients with Cushing disease from the LINC 3 and LINC 4 programs
Luciana Martel-Duguech · Ghislaine Houde · Constance Chik · Syed Ali Imran · André Lacroix
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1902818
Original Research
Published
Selective inhibition of aldosterone production modulates human adrenocortical (HAC15) cell fate
Kha Chin Long · Amnani Aminuddin · Najiah Ajlaa Ayub · Geok Chin Tan · A. Rahman A. Jamal · Nor Azian Abdul Murad · Nor Adzimah Johdi · Celso E. Gomez-Sanchez · Norlela Sukor · Morris J. Brown · Elena A. Azizan
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1872432
Original Research
Published
Evaluation of inflammatory status and macrophage polarization in premature ovarian insufficiency mice induced by chemotherapy
Maoxing Tang · Manzhi Zhao · Yangcheng Yao · Xiqian Zhang · Fenghua Liu
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1798400
Policy and Practice Reviews
Published
Obesity in adults: overview of a clinical practice guideline for South Africa
Marli Conradie-Smit · Wayne May · Clayton Arendse · Jason Bantjes · Zaheer Bayat · Elna Barnard · Sindeep Bhana · Nomathemba Chandiwana · Annibale Cois · Paula N. Diab · Zodwa Dire · Virginia R. Fourie · Julia H. Goedecke · Jocelyn Hellig · Zachary Koto · Kathleen Mawson · Makama Andries Monyeki · Angela Murphy · Christina Nieuwoudt · Marisa Noeth · Nicole Pearce · Joanna Skelton · Thinus (JGM) Smit · Sanjeev Sockalingam · Francois H. van Zyl · Jeanne Lubbe
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1875018
Case Report
Published
Case Report: Laser thermal ablation for severe primary hyperparathyroidism in a pregnant patient with MEN1 syndrome
Mateusz Obal · Marcin Motyka · Grzegorz Sokołowski · Tomasz Piskorz · Hubert Huras · Alicja Hubalewska-Dydejczyk
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1964081
Original Research
Published
Timing luteal urinary pregnanediol glucuronide assessment using urinary luteinizing hormone: agreement with ultrasound-determined ovulation
Rene Leiva · Rene Ecochard · Jonathan Yang
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1992715
Clinical Trial
Published
Efficacy of Huangbai liniment for diabetic foot ulcers with multidrug-resistant organism infection: a randomized controlled multicenter trial
Ning Wang · Gang Wang · Min Zhou · Keren Zhang · Tong Zhou · Xuewan Wang · Guangyao Yang · Lijuan Deng · Tianyi Huang · Shang Ju
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1926211
Original Research
Published
Sex differences in sleep and memory relationships in older adults at risk for Alzheimer’s disease
Negin Sattari · Abhishek Dave · Ivy Y. Chen · Kitty K. Lui · Miranda G. Chappel-Farley · Destiny E. Berisha · Kate E. Sprecher · Brady A. Riedner · Stephanie Jones · Barbara B. Bendlin · Bryce A. Mander · Ruth M. Benca
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1930177
Perspective
Published
A retrospective real-world study on semaglutide effectiveness in patients with obesity: differences between patients with and without food craving
Simona Bertoli · Federica Barbera · Chiara Cappellini · Alice Gotti · Alberto Battezzati
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1927180
Original Research
Published
Exercise-induced hypoalgesia following HIIT: associations with cardiac interoceptive accuracy and the moderation by physical fitness
Maria Geisler · Marco Herbsleb · Alexander Ritter · Feliberto de la Cruz · Yuraj Gubpta · Andy Schumann · Ilona Croy · Karl-Jürgen Bär
Frontiers in Psychology
doi 10.3389/fpsyg.2026.1953847
Original Research
Published
Altered cytokine profiles and elevated lactate levels in children with autism spectrum disorder: indications of a dysregulated immune-metabolic network?
Nicole Beyer · Theresia Volk · Hella Luksch · Melanie Ring · Nora C. Vetter · Angela Roesen-Wolff · Min Ae Lee-Kirsch · Veit Roessner
Frontiers in Psychiatry
doi 10.3389/fpsyt.2026.1904470
Original Research
Published
Effects of an eight-week mindfulness-informed psychoeducational intervention delivered during physical education lessons on self-reported aggression and impulsivity in adolescents
Walid Selmi · Achraf Hammami · Said Ben Hassen · Yassine Negra · Raouf Hammami · Roland van den Tillaar
Frontiers in Psychology
doi 10.3389/fpsyg.2026.1958309
Systematic Review
Published
A systematic review of machine learning approaches for MRI-based brain tumor analysis
Ivan Viktorovich Brak · Merich Doruk Kaymakcioglu · Vasiliy Vladimirovich Belousov · Zhanibek Baiturlin · Daultay Azamatovich Batyrkhanov · Daniil Olegovich Mityagin · Manzura Zholdassova · Almira Melsovna Kustubayeva
Frontiers in Computational Neuroscience
doi 10.3389/fncom.2026.1937002
Original Research
Published
Genomic insights into multidrug and extensively drug-resistant Klebsiella pneumoniae from bloodstream infections at three Zambian tertiary hospitals
Joseph Yamweka Chizimu · Harvey Kakoma Kamboyi · Maisa Kasanga · Taona Sinyawa · Misheck Shawa · Ruth Nakazwe · Steward Mudenda · Joseph Njung’e · Susan Kiiru · Mungunsar Chuluun · Chileshe Lukwesa · Zoran Muhimba · Victor Daka · Dianah Tibatemwa · Everlyn Wesangula · O-Tipo Shikanga · Sandra Diana Mwadetsa · Nchimunya Machila · Veronica Chuchu · Zachariah Mupila · Peter Clement Lasuba · Yasuhiko Suzuki · Flavien Nsoni Bumbangi · Roma Chilengi
Frontiers in Antibiotics
doi 10.3389/frabi.2026.1933211
Original Research
Published
TSC1-mTORC1 signaling in Alzheimer’s disease: an integrated bioinformatic analysis linking gene expression to neuropathology
Zheng Liu · Yuchen Yu · Yu Wang · Shuohan Ning · Tongshuai Huang · Jingqi Li · Sihan Fan · Chaolong Lu
Frontiers in Aging Neuroscience
doi 10.3389/fnagi.2026.1920487
Original Research
Published
Physiological discordance between clinical examination, bioimpedance spectroscopy, and lung ultrasound in maintenance hemodialysis patients without heart failure
Irwing R. Benites-Flores · Javier Rodríguez Revilla · Alvaro Taype-Rondan · Liliana C. Fernández-Anticona · Pedro Augusto Prado Ramírez · Nelly Seminario Alegre · Celia Rodríguez Tudero · Esperanza Moral Berrio · Elena Jimenez Mayor · Avinash Chandu Nanwani · José C. De la Flor
Frontiers in Nephrology
doi 10.3389/fneph.2026.2000700