Review
Published
Oral delivery of biologics: from barrier-limited formulation to active convective transport
Sarfaraz K. Niazi
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1783113
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 184 articles
Original Research
Published
Phα1β cardiovascular safety pharmacology using the telemetry system in rats
Celio José Castro Junior · Marcus Vinícius Gomez
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1749055
Mini Review
Published
Epi-liquidomics: redefining cancer diagnostics through epigenetic profiling
Shahper Nazeer Khan · Mohammad Harris Siddiqui · Aamir Ahmad · Luca Guarnera · Salamatu Tijjani Isah
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1813822
Systematic Review
Published
Nanoparticle-mediated mRNA delivery for cancer, autoimmunity, and genetic diseases: a rapid review
Okechukwu Paul-Chima Ugwu · Fabian C. Ogenyi · Mariam Basajja · Chinyere N. Ugwu · Mundu M. Mustafa · Michael Ben Okon
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1793322
Mini Review
Published
The anesthesiologist's role in preventing chronic post-surgical pain and opioid use through neurobiological programming: a mini review
Trisha Nair · Ofelia Loani Elvir-Lazo · Robert Wong
Frontiers in Anesthesiology
doi 10.3389/fanes.2026.1766035
Review
Published
Revisiting old drugs and drug combinations for polycythemia vera and related neoplasms
Gökhan Mergen · Hans C. Hasselbalch
Frontiers in Hematology
doi 10.3389/frhem.2026.1749376
Original Research
Published
Assessing vocal changes through spectral analyses of vocalizations in a cerebellar-specific dystonia mouse model
Austin L. Fitzgerald · Jonathan A. Coello · Alyssa M. Lyon · Breanne L. Dao · Meike E. van der Heijden
Dystonia
doi 10.3389/dyst.2026.15530
Original Research
Published
Dose optimization of inhaled tigecycline in humans to overcome inherent adverse events and maximize bacterial clearance using a physiologically-based pharmacokinetic modeling approach
Hyunseo Park · Amarinder Singh · Ashish Srivastava · Bhargavi Thalluri · Christelle J. Mathieu · Paridhi Gupta · Camron M. Pearce · Malik Zohaib Ali · Ilham M. Alshiraihi · Sara E. Maloney Norcross · Anthony J. Hickey · Mercedes Gonzalez-Juarrero · Bernd Meibohm
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1762713
Mini Review
Published
Species barriers in AAV tropism: mechanisms, models, and emerging solutions for clinical translation
Xinyuan Xu
Acta Biochimica Polonica
doi 10.3389/abp.2026.15939
Original Research
Published
Towards a standardized diabetic prolonged wound healing model in hairless SKH1 mice
Elle Koivunotko · Julia Monola · Chris S. Pridgeon · Jere Linden · Riina Harjumäki · Emrah Yatkin · Mari Madetoja · Marjo Yliperttula
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10857
Original Research
Published
Radiobiological evaluation of the therapeutic effect of silver-111 for the ISOLPHARM project
Alberto Arzenton · Aurora Leso · Francesca Rana · Giulia S. Valli · Elena Delgrosso · Laura Cansolino · Cinzia Ferrari · Silva Bortolussi · Isabella Guardamagna · Giorgio Baiocco · Giorgio Grosso · Davide Serafini · Andrea Gandini · Valerio Di Marco · Antonietta Donzella · Emilio Mariotti · Marcello Lunardon · Devid Maniglio · Germano Bonomi · Alberto Andrighetto
Frontiers in Nuclear Medicine
doi 10.3389/fnume.2026.1773638
Original Research
Published
Feasibility in the detection of sentinel lymph node-associated blood vessels using intravital microscopy in patients undergoing sentinel lymph node biopsy for melanoma
Emmanuel Gabriel · Daniel T. Fisher · Minhyung Kim · Kristopher Attwood · Xiaoyi Ma · Valerie Francescutti · John M. Kane · Sharon S. Evans · Joseph J. Skitzki
Frontiers in Imaging
doi 10.3389/fimag.2026.1758694
Original Research
Published
Metabolomics-guided identification of bioactive phytometabolites from South African plants targeting neuroblastoma
Mmei Cheryl Motshudi · Clarissa Marcelle Naidoo · Chikwelu Lawrence Obi · Benson Chucks Iweriebor · Earl Prinsloo · Muhammad Sulaiman Zubair · Nqobile Monate Mkolo
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10867
Original Research
Published
Across preclinical and clinical platforms, approved and investigational psychiatric drugs share pathways and associate with similar molecular functions
Emily Su · Nico Matthew S. Valencia · Jarod Le · Emily Liu · Jennifer L. Wilson
Frontiers in Drug Discovery
doi 10.3389/fddsv.2025.1686789
Systematic Review
Published
Honeybee venom therapy and viral infection: a systematic synthesis of venom antiviral activity
Sirwan Sleman · Zaniar A. Abass · Barham J. Abdullah · Omed I. Abid · Masood B. Ameen
Frontiers in Virology
doi 10.3389/fviro.2026.1751614
Review
Published
Local delivery of tranexamic acid for hemorrhage control in trauma: a narrative review
Henry T. Peng · Christian J. Kastrup · Catherine Tenn · Andrew Beckett
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1771095
Review
Published
Natural product based approaches to overcome Candida glabrata and emerging AMR threats
Binaya Krushna Sahu · Sudipta Kumar Patra · Mahesh Chandra Sahu · Sujogya Kumar Panda
Frontiers in Antibiotics
doi 10.3389/frabi.2026.1767032
Perspective
Published
Acinetobacter baumannii: challenges presented by a drug-resistant pathogen
E.K. Goncalves · L.A. Ramos · A. Seibert · L.M. Ribeiro · S.L. McDuffie · M.C. Murray · S.E. Fiester
Frontiers in Bacteriology
doi 10.3389/fbrio.2025.1734537
Review
Published
Receptor-targeted technetium-99m radiopharmaceuticals: increasing access to molecular imaging in healthcare
Michelle T. Ma
Frontiers in Chemical Biology
doi 10.3389/fchbi.2025.1729615
Review
Published
Aging and Alzheimer’s: the critical role of mitochondrial dysfunction and synaptic alterations
Pinky · Zitin Wali · Neha · Prachi Tiwari · Mohamed El-Tanani · Syed Arman Rabbani · Suhel Parvez
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2025.1676317
Review
Published
Photobiomodulation therapy in neuropathic pain: mechanisms, evidence, and future directions
Daniel O. Martins · Igor R. C. Rocha · Linda R. Watkins · Marucia Chacur
Frontiers in Photonics
doi 10.3389/fphot.2025.1730347
Systematic Review
Published
CRISPR–Cas9 mediated gene therapy in inherited bone marrow failure syndromes
Nadeesha J. S. Munugoda Hewa · Rajendra KC · Alex W. Hewitt · Kirsten A. Fairfax
Frontiers in Hematology
doi 10.3389/frhem.2025.1713610
Sensors
Published
ASIX: Single-photon, energy resolved X-ray imaging with 50 μ m hexagonal hybrid pixel
Massimo Minuti · Luca Baldini · Roberto Beccherle · Ronaldo Bellazzini · Ashish Bisht · Maurizio Boscardin · Alessandro Brez · Paolo Bruschi · Marco Ceccanti · Matteo Centis Vignali · Luca Frontini · Luigi Gaioni · Omar Hammad Ali · Luca Latronico · Valentino Liberali · Guido Magazzù · Alberto Manfreda · Massimo Manghisoni · Fabio Morsani · Leonardo Orsini · Luca Palini · Melissa Pesce Rollins · Michele Pinchera · Massimo Piotto · Alessandro Profeti · Paolo Prosperi · Lodovico Ratti · Andrea Ria · Sabina Ronchin · Carmelo Sgrò · Stefano Silvestri · Gloria Spandre · Alberto Stabile · Gianluca Traversi · Gabriella Trucco · Monica Vasquez · Danny Zanardo
Frontiers in Sensors
doi 10.3389/fsens.2025.1599365
Review
Published
Is it possible to prevent excessive synaptic pruning in schizophrenia? Possibilities and limitations
Agnieszka Pawlak · Jakub Stefanowicz · Zofia Kotkowska · Agata Gabryelska · Marcin Sochal · Filip Napieraj · Magdalena Kotlicka-Antczak · Dominik Strzelecki
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2025.1656232
Lab on a Chip Technologies
Published
Organs-on-a-chip for global equity: a perspective from Guatemala on advancing biomedical research in resource-limited settings
Maria D. Cabrera · Andrea C. del Valle
Frontiers in Lab on a Chip Technologies
doi 10.3389/frlct.2025.1669220
Medical Engineering
Published
Confocal fluorescence microscopy for real-time breast cancer diagnosis: current advances and future perspectives
Khushi Vyas · Ahmed Ezzat · Nicholas Holford · Rathi Ramakrishnan · Daniel R. Leff
Frontiers in Medical Engineering
doi 10.3389/fmede.2025.1607453
Parasitology
Published
Guanine derivatives as promising candidates for the development of purine-based antimalarial drugs
Worlanyo Tashie · Harry P. de Koning · Nancy O. Duah-Quashie · Neils B. Quashie
Frontiers in Parasitology
doi 10.3389/fpara.2025.1634209
Tuberculosis
Published
Patterns of Mycobacterium tuberculosis genotypes and resistance mutations in patients with pulmonary multidrug-resistant tuberculosis in Sverdlovsk Oblast, Russia
Tatiana Umpeleva · Elena Mazurina · Leonid Lavrenchuk · Sven G. Hinderaker · Einar Heldal · Andrei Mariandyshev · Diana Vakhrusheva · Irina Vasilieva
Frontiers in Tuberculosis
doi 10.3389/ftubr.2025.1406536
Bacteriology
Published
Preclinical validation of electrospun fibers to achieve vaginal colonization by Lactobacillus crispatus
Christy N. Armstrong · Sudeshna Saha · Marnie A. Aagard · Mohamed Y. Mahmoud · Nissi M. Varki · Nicole M. Gilbert · Hermann B. Frieboes · Warren G. Lewis · Amanda L. Lewis
Frontiers in Bacteriology
doi 10.3389/fbrio.2025.1562077
Thermal Engineering
Published
Magnetic particle imaging resolution needed for magnetic hyperthermia treatment planning: a sensitivity analysis
Shreeniket Pawar · Nageshwar Arepally · Hayden Carlton · Joshua Vanname · Robert Ivkov · Anilchandra Attaluri
Frontiers in Thermal Engineering
doi 10.3389/fther.2025.1520951
Molecular Medicine
Published
Immune-checkpoint-inhibitor therapy directed against PD-L1 is tolerated in the heart without manifestation of cardiac inflammation in a preclinical reversible melanoma mouse model
Caroline Schoenherr · Stefan Pietzsch · Cristina Barca · Franziska E. Müller · Frauke S. Bahr · Martina Kasten · Andre Zeug · Sergej Erschow · Christine S. Falk · Evgeni Ponimaskin · James T. Thackeray · Denise Hilfiker-Kleiner · Melanie Ricke-Hoch
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2024.1487526
Lab on a Chip Technologies
Published
How organ-on-a-chip is advancing cancer research and oncology - a cancer hallmarks’ perspective
Leela Rani Avula · Piotr Grodzinski
Frontiers in Lab on a Chip Technologies
doi 10.3389/frlct.2024.1487377
Medical Engineering
Published
Gluing osteochondral fragments: development of a novel strategy for dual adhesive application in a preclinical model
Alicja J. Bojan · Peyman Karami · Philip Procter · Dominique P. Pioletti
Frontiers in Medical Engineering
doi 10.3389/fmede.2024.1484232
Drug Delivery
Published
Glucagon-like peptide-1 receptor agonists for treatment of diabetes and obesity: advantage of oral delivery
R. R. C. New · M. Bogus · G. N. Travers · U. Hahn · A. Vaiceliunaite · M. Burnet · J. H. Wang · H. Wen
Frontiers in Drug Delivery
doi 10.3389/fddev.2024.1456654
Biomaterials Science
Published
Methodological aspects of correlative, multimodal, multiparametric breast cancer imaging: from data acquisition to image processing for AI-based radioproteomics in a preclinical setting
Silvester J. Bartsch · Klára Brožová · Christoph Fürböck · Joachim Friske · Daniela Laimer-Gruber · Thomas H. Helbich · Marcus Hacker · Claudia Kuntner · Klaus Kratochwill · Lukas Kenner · Georg Langs · Katja Pinker · Thomas Wanek
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2024.1420114
Biomaterials Science
Published
Correlated multimodal imaging in life sciences: lessons learnt
Pavitra Sokke Rudraiah · Rafael Camacho · Julia Fernandez-Rodriguez · Dror Fixler · Jan Grimm · Florian Gruber · Matúš Kalaš · Christopher Kremslehner · Claudia Kuntner · Daniela Kuzdas-Wood · Joakim Lindblad · Julia G. Mannheim · Martina Marchetti-Deschmann · Perrine Paul-Gilloteaux · Paula Sampaio · Peter Sandbichler · Anna Sartori-Rupp · Nataša Sladoje · Paul Verkade · Andreas Walter · Samuele Zoratto
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2024.1338115
Photonics
Published
Dual-modal photoacoustic and ultrasound imaging: from preclinical to clinical applications
Nikhila Nyayapathi · Emily Zheng · Qifa Zhou · Marvin Doyley · Jun Xia
Frontiers in Photonics
doi 10.3389/fphot.2024.1359784
Medical Engineering
Published
Advanced materials and biofabrication technologies to design in vitro functional central nervous system models
Cecilia Traldi · Vanessa Chiappini · Giovanna Menduti · Chiara Tonda-Turo · Marina Boido
Frontiers in Medical Engineering
doi 10.3389/fmede.2023.1270943
Molecular Medicine
Published
Astrocytes in stroke-induced neurodegeneration: a timeline
Eileen Collyer · Elena Blanco-Suarez
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2023.1240862
Neuroscience
Published
FDG-PET imaging in mild traumatic brain injury: a critical review
Kimberly R. Byrnes · Colin M. Wilson · Fiona Brabazon · Ramona von Leden · Jennifer S. Jurgens · Terrence R. Oakes · Reed G. Selwyn
Frontiers in Neuroenergetics
doi 10.3389/fnene.2013.00013