Review
Published
Histotripsy in tumor therapy: advances in non-thermal mechanical ablation, immune modulation, and clinical translation
Yangyang Ma · Xinan Long · Jiangpeng Cheng · Lizhi Niu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1858144
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Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 5006 articles
Review
Published
Nutritional regulation of the tumor immune microenvironment: metabolic mechanisms, immunotherapy response, and nursing implications
Danwei Zhong · Congjue Li · Zunyao Xiao
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938564
Review
Published
Tebentafusp induces systemic immune activation, but tumor immune remodeling remains incompletely validated: a narrative review in metastatic uveal melanoma
Francesca Rifaldi · Filippo De Braud · Michele Del Vecchio · Lorenza Di Guardo
Frontiers in Immunology
doi 10.3389/fimmu.2026.1934256
Review
Published
Precision immuno-oncology in triple-negative breast cancer: from PD-L1 to multimodal biomarkers, ADC–ICI combinations, and global real-world integration
Jingna Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1911879
Original Research
Published
House dust mite drives biphasic immunomodulation of inflammatory dendritic epidermal cells via glucose metabolism in atopic dermatitis
Ying Zhao · Cuie Gao · Xin Sui · Lan Ge · Huan Wang · Sisi Deng · Qiquan Chen · Lu Liu · Jing Tian · Tong Mu · Li Wang · Zhiqiang Song
Frontiers in Immunology
doi 10.3389/fimmu.2026.1887390
Review
Published
Lactate dynamics at the Pseudomonas aeruginosa –host interface: bacterial metabolism, host defense, and emerging links to histone lactylation
Yi Jian · Zhijie Wu · Yuqiang Liang · Jin Cao · Mei Li · Fashuang Yang · Ke Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1979311
Review
Published
Botanical polysaccharides as veterinary vaccine adjuvants: structure, receptors, and translational limits
Ran Guan · Chaoyun Yang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1982641
Review
Published
Microbial-derived metabolites in cancer: evidence boundaries, immune mechanisms and translational pathways
Xuefeng Shi · Shunjun Wang · Wenhao Ouyang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1947330
Original Research
Published
Low-frequency passive mechanical stimulation produces antidepressant-like effects in rats involving gut–brain axis modulation
Rong Gao · Wenjing Pu · Yifei Lv · Liqiong Liu · Yan Zhao · Hao Liu · Li Chen · Nan Guan · Hongen Li
Frontiers in Immunology
doi 10.3389/fimmu.2026.1928978
Original Research
Published
Early dynamics of eosinophils and the neutrophil-to-lymphocyte ratio are associated with severe immune-related adverse events during nivolumab therapy for metastatic renal cell carcinoma
Ondřej Fiala · Jan Králíček · Jindřich Kopecký · Michal Vočka · Tomas Buchler · Hana Študentová · Jana Obertová · Beáta Rondzíková · Martin Matějů · Dominik Šafčák · Matej Hrnčár · Peter Priester · Martina Spisarová · Anežka Zemánková · Radka Lohynská · Michaela Tkadlecová · Lucie Grmelová · Petr Stránský · Bohuslav Melichar · Patrik Palacka · Alexandr Poprach
Frontiers in Immunology
doi 10.3389/fimmu.2026.1944728
Mini Review
Published
A proposed retinal venular immune gate: a mini review of perivascular macrophages and basement-membrane organization
Zhiqing Huang · Zijian Huang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1970491
Review
Published
Progress in research on gut microbiota regulation of tumorigenesis, progression, and therapeutic response via inflammatory cytokines
Yan Liu · Dan Zang · Jun Chen
Frontiers in Immunology
doi 10.3389/fimmu.2026.1922678
Review
Published
Calcium-dependent conformational transitions and ligand binding regulation of C-reactive protein: a comprehensive review
Bin Cheng · Zhi-Xin Yao · Guo-Qiang Wu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1963529
Mini Review
Published
Cerebrospinal fluid metagenomic next-generation sequencing for culture-negative anaerobic central nervous system infection involving Prevotella oris : attribution challenges in low-biomass specimens
Yan Li · Minghua Fan · Yuyuan Hu · Yuhang Yang · Wenyuan Li · Wei Zhang · Yanhong Wang
Frontiers in Immunology
doi 10.3389/fimmu.2026.1896093
Mini Review
Published
T-cell metabolic reprogramming in systemic lupus erythematosus: linking intracellular metabolism to effector differentiation and senescent-like/exhausted-like states
Yi Zou · Zhichu Ren · Yuki Kudo · Michihito Kono
Frontiers in Immunology
doi 10.3389/fimmu.2026.1961063
Mini Review
Published
Metabolic stress and macrophage efferocytosis in osteoarthritis: mechanisms and therapeutic implications
HaoYang Wu · DeChao Yuan · RenJian He · ShiWei Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1999085
Original Research
Published
Integrative single-cell and bulk transcriptomic analysis identifies monocyte/macrophage senescence-associated candidate genes in pulmonary arterial hypertension
Xiaojun Chen · Weibin Wu · Yilong Liu · Guili Lian · Qingquan Liu
Frontiers in Immunology
doi 10.3389/fimmu.2026.1938985
Original Research
Published
Spatial analysis of placentae during congenital cytomegalovirus infection suggests distinct cellular profiles in immune and trophoblast cells: an exploratory study
Elise Sintim-Aboagye · Huy Quang Quach · Indrani Mukherjee · Will Sherman · Katelyn T. Nguyen · Neil Ferland · Sheila Farnan · Kamila Otrubova · Namisha Verma · Dawn Littlefield · Sohan Punia · Erica Johnson · Mark Blackstad · Mark R. Schleiss · Andrew P. Norgan · Clive M. Gray · Elizabeth Ann L. Enninga · Rana Chakraborty
Frontiers in Immunology
doi 10.3389/fimmu.2026.1885923
Original Research
Published
Cross-lineage anomaly detection of microRNA expression: a framework for deriving exploratory candidate biomarkers in sarcoma
Mritunjoy Dey · Piotr Remiszewski · Ewelina Perdas · Paweł Golik · Jakub Piątkowski · Anna M. Czarnecka
Frontiers in Genetics
doi 10.3389/fgene.2026.1907450
Review
Published
MicroRNA cargo of extracellular vesicles as mediators of immune dysregulation in pediatric immune thrombocytopenia: from pathogenetic drivers to biomarkers
Lucia Argenziano · Maria Maddalena Marrapodi · Giuseppe Di Feo · Oriana Di Domenico · Francesca Rossi · Alessandra Di Paola
Frontiers in Genetics
doi 10.3389/fgene.2026.1951187
Review
Published
Alcohol-induced placental vasculopathy reprograms the placental-fetal cardiovascular axis: angiogenic mechanisms linking maternal alcohol exposure to developmental cardiovascular programming
Elisa Cebral
Frontiers in Physiology
doi 10.3389/fphys.2026.1917947
Review
Published
Silencing without clearing: pharmacological modulation of the SASP in aging and disease
Lukas Fresser · Zofia Chrienova · Jan Gebrt · Patrik Oleksak · Kamil Kuca · Eugenie Nepovimova
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1911529
Methods
Published
A high-throughput 96-well plate method to measure human uterine contractility
Emilie Huon · Justine Rayssac · Marie-Charlotte Lamau · Carole Abo · Gauthier Dietrich · Ylann Abrahami · Jordan Kouby · Julien Adam · Nicolas R. Chevalier
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1953934
Original Research
Published
Fibrinolytic suppression and increased uterine artery resistance are associated with embryo resorption in DBA/2 mated CBA/J mice
Youchen Liu · Jingjing Wang · Boning Huang · Ping Tang · Fangle Liu · Yuying Zheng · Yilin Li · Huiyi Xie · Liuqing Lin · Xinrong Yang · Xiubing Zhang · Jie Gao · Baoqin Lin
Frontiers in Physiology
doi 10.3389/fphys.2026.1942168
Original Research
Published
Berberine ameliorates thioacetamide-induced liver injury in zebrafish through PPARγ signaling and restores bile acid homeostasis
Peng Sun · Jun Wu · Xiaoyu Zhu · Yanshuang Ren · Zhanyi Zhou · Wenjian Zhen · Yuan Ma · Xue Ding · Menghan Huang · Yuying Zhang · Wei Gong · Hao Wang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1881966
Review
Published
NEDD4-1: from molecular mechanisms to clinical translation in human diseases
Haifen Tian · Yongsheng Huang · Yun Liang · Chengjun Huang · Bingbing Wei · Chang-Neng Liao · Weijie Zhou
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1897001
Review
Published
Early life stress, lower urinary tract dysfunction, and respiratory disease: a proposed shared-mechanism framework
Tadanobu Chuyo Kamijo · Mayoko Tsuji
Frontiers in Physiology
doi 10.3389/fphys.2026.1929695
Original Research
Published
EGFR-TKI-associated colitis in non-small cell lung cancer: a retrospective characterization of clinical, radiographic, endoscopic, and histopathologic features
Shujun Wang · Chen Tan · Pufang Shi · Ya Li · Hefeng Zhan · Jiajing Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1935622
Original Research
Published
Agreement between upper-arm and wrist cuff occlusion for the assessment of vascular reactivity by digital thermal monitoring
Hamidreza Mohammadi · Ali Hashemi · Timothy O’Brien · Hamed Ghoshouni · Hirofumi Tanaka · Robert A. Kloner · Morteza Naghavi
Frontiers in Physiology
doi 10.3389/fphys.2026.1961953
Systematic Review
Published
Exercise programmes incorporating proximal kinetic-chain components in flexible flatfoot: a systematic review and meta-analysis of foot posture, neuromuscular, and dynamic outcomes
Zheyu Xiong · Jiguo Liang · Guanghua Li
Frontiers in Physiology
doi 10.3389/fphys.2026.1959545
Original Research
Published
Independent correlates of vancomycin steady-state trough concentration among patients undergoing combined CABG and valve surgery: observational findings for intra-aortic balloon pump support
Bei-bei Shao · Tao Feng · Ji-cheng Jiang · Wen-lu Xing · Ming Ni · Lu-lu Li · Chao Liu · Shu-ping Meng · Yong-cheng Ma · Ai-feng Wang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1888382
Original Research
Published
Associations between spike velocity and physical characteristics in elite sitting volleyball players
Shaocheng Sun · Meiling Ren · Jinhu Yan
Frontiers in Physiology
doi 10.3389/fphys.2026.1992570
Original Research
Published
Quercetin attenuates polystyrene nanoplastic-induced intestinal barrier injury through modulation of macrophage inflammatory responses
Jian Kang · Heng Yang · Yan Wang · Xin Zhang · Chunyang Zhu · Yanhong Zhou · Yanqin Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1973458
Original Research
Published
Reporting signals of selected extrapyramidal adverse events with four newer second-generation antipsychotics: a disproportionality analysis of FAERS spontaneous reports
Pan Ma · Qin Xiao · Yunpei Zhao · Xin Zhang · Huan Ma · Dan Chen · Linli Xie
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1921943
Original Research
Published
Whole-exome sequencing reveals cumulative rare variant burden associated with susceptibility to anti-tuberculosis drug-induced liver injury in a Han Chinese cohort
Yang Hao · Xiaoqing Zhang · Daiyun Huang · Shengyin Qin · Yunxiao Lin · Jianwen Ruan · Lu Shen · Na Zhang · Zhenting Wang · Cong Huai · Jianquan Zhang
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1952049
Original Research
Published
Depression, anxiety, and cognitive function in patients with ischemic cerebrovascular disease: a cross-sectional study based on the Montreal Cognitive Assessment
Weiwen Chen · Yinan Zhuo
Frontiers in Neurology
doi 10.3389/fneur.2026.1854573
Review
Published
P2Y 12 inhibition, adenosine signaling, and bone remodeling: differential skeletal pharmacology of antiplatelet agents
Zhuoqun Ma · Wei Luo · Yuanbo Li · Hong Li · Chaomin Li
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1897702
Mini Review
Published
From emergency myelopoiesis to trained immunity? Reframing post-stroke myeloid reprogramming along the brain-bone marrow axis
TongZhu Wei · YongJiu Wang
Frontiers in Neurology
doi 10.3389/fneur.2026.1976078
Review
Published
WRN helicase addiction in MSI-H colorectal cancer: biomarker-guided pharmacology, resistance evolution, and implications for other gastrointestinal cancers
Peng Zhang · Jiangsu Gan · Hongying Wang · Yali Xiong
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1962228
Correction
Published
Correction: Mechanism-aware and safety-validated AI for drug repurposing: a critical review and translational pharmacology framework
Moumita Hazra · Harishchander Anandaram
Frontiers in Pharmacology
doi 10.3389/fphar.2026.2009326
Systematic Review
Published
The application of square-stepping exercise in patients with stroke: a scoping review
Yali Yan · Juan Xu · Jiaxin Yao · Yuanyuan Liu · Mengdan Li · Xinxin Geng
Frontiers in Neurology
doi 10.3389/fneur.2026.1952887
Systematic Review
Published
Efficacy of digital interventions for patients with post-stroke aphasia: a systematic review and network meta-analysis
Junjie Shi · Yue Sun · Jingyi Zhang · Zeyu Yang · Jia Hu · Liang Zhi · Qingfang Zhang · Yulong Wang · Jianjun Long
Frontiers in Neurology
doi 10.3389/fneur.2026.1936067
Addendum
Published
Addendum: A modular, deep learning-based holistic intent sensing system tested with Parkinson's disease patients and controls
Joseph Russell · Jemma Inches · Camille B. Carroll · Jeroen H. M. Bergmann
Frontiers in Neurology
doi 10.3389/fneur.2026.1972445
Mini Review
Published
Functional divergence of the synapsin family in glioblastoma: Synapsin III as a candidate differentiation-restoring node
Xiangyu Dai · Yujie Ji · Zheng Cai · Haixin Zeng · Yi Li · Haining Zhou · Xu Zhang · Bing Li
Frontiers in Neurology
doi 10.3389/fneur.2026.1976698
Mini Review
Published
Mapping the neural basis of the perception of “flow of time”: interval timing and mental time travel in the human brain
Ryuta Ochi · Mitsuru Kawamura
Frontiers in Neurology
doi 10.3389/fneur.2026.1960572
Original Research
Published
Effectiveness and safety of imeglimin in routine clinical practice among Indian patients with type 2 diabetes mellitus: a prospective, non-interventional, real-world observational study (INDI-TIMES 2.0)
Debmalya Sanyal · Anuj Maheshwari · Subrata Chakrabarti · Manoj Chawla · Mangesh Tiwaskar · Soujanya Kunapa Reddy · S Sridhar · Arthur Joseph Ashirvatham · Rituraj Benode Deb · Gayathry V M
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1973270
Original Research
Published
Resistance to thyroid hormone alpha associated with a novel THRA ligand-binding domain variant: familial clinical, biochemical, skeletal, and exploratory cerebral FDG-PET/CT metabolic findings
Denisse Mata-Salgado · Juan José Morales-Suárez · Alfredo Adolfo Reza-Albarrán · Rodrigo Hernández-Ramírez · Miguel Angel Corza-Ayala · José Antonio Cienfuegos-Alvear · Ana María González-Jaimes · Iván Martínez-Duncker · Carmen Alaez-Verson
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1891019
Original Research
Published
Impact of unilateral salpingectomy on ovarian reserve and long-term reproductive outcomes in reproductive-aged women
Yanna Zhou · Yiting Yang
Frontiers in Endocrinology
doi 10.3389/fendo.2026.1952475