Original Research
Published
Alzheimer’s disease diagnosis based on gene selection and cross-tissue validation
Xiaolan Zhang · Xiaotong Tang · Qian Bo · Yu Ma · Fang Shi · Hongpeng Hou
Frontiers in Genetics
doi 10.3389/fgene.2026.1890236
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Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 645 articles
Original Research
Published
Feedback-enabled digital twin and explainable artificial intelligence framework for predictive resilience and adaptive decision-making in disrupted supply chains
Charles Onyeka Nwamekwe · Nkemakonam Chidiebube Igbokwe · Ifeanyichukwu Benjamin Unigwe
Frontiers in Sustainability
doi 10.3389/frsus.2026.1907543
Original Research
Published
High-value-added forest product exports, the digital economy, and the efficiency of forest ecological product value realization
Hui Pan
Frontiers in Forests and Global Change
doi 10.3389/ffgc.2026.1917095
Original Research
Published
A multi-source empirical audit of blockchain and DeFi: concentration, intelligent agents, and mechanism design
William Villegas-Ch · Aracely Mera Navarrete · Rommel Gutierrez · Paul Sarango-Lalangui
Frontiers in Blockchain
doi 10.3389/fbloc.2026.1949598
Original Research
Published
A unified unsupervised deep learning and stride threat modeling framework for multi-domain cyber-physical security in nuclear digital twins
Mehtab Alam · Akshay Chamoli · Ashraf Ali · Abdullah Alourani
Frontiers in Mechanical Engineering
doi 10.3389/fmech.2026.1926649
Original Research
Published
Single-cell transcriptomic analysis identifies vascular smooth muscle cell transcriptional programs associated with human carotid plaque remodeling
Yi-Jie Lu · Xue-Guang Lin · Ting Wang · Fan-Xuan Huang · Ying Deng · Shuai Jiang · Jing Dong Tang · Bo Yu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1950061
Technology and Code
Published
singIST: an R/bioconductor library and quarto dashboard for automated single-cell comparative transcriptomics analysis of disease models and humans
Aitor Moruno-Cuenca · Sergio Picart-Armada · Alexandre Perera-Lluna · Francesc Fernández-Albert
Frontiers in Genetics
doi 10.3389/fgene.2026.1952333
Systematic Review
Published
Beyond the hype: an empirical assessment of quantum computing in bioinformatics
Manuel Arcieri · Paolo Zuliani · Giovanni Carotenuto · Meryam Carrus · Tiziana Castrignanò
Frontiers in High Performance Computing
doi 10.3389/fhpcp.2026.1923360
Hypothesis and Theory
Published
Mentorship as metadata: clinical annotation and the limits of real-world data in oculoplastic surgery
Itay Nitzan · Tehila Shlomov · Zvi Gur
Frontiers in Ophthalmology
doi 10.3389/fopht.2026.1972892
Perspective
Published
Underrepresentation of African surveillance data in global arbovirus modeling
Rosheen S. Mthawanji
Frontiers in Tropical Diseases
doi 10.3389/fitd.2026.1894025
Original Research
Published
Integrative multi-omics characterization of KLRB1/CD161 in diffuse large B-cell lymphoma: associations with immune context, subtype biology, and therapeutic response
Erwei Li · Yingying Tang · Yuanyuan Wanyan · Yu Liang
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1903725
Original Research
Published
Geochemical connectivity among mine tailings, soils, sediments, and waters in a historical mining basin integrating multivariate statistics and exploratory random forest modeling
Luisa Fernanda Rueda-Garzon · Alejandro Carrillo-Chávez · Raúl Miranda-Avilés · Daniela Calvo-Ramos · Jorge Luis Morales-Martínez · Carolina Muñoz-Torres · Rocío García-Martínez
Frontiers in Geochemistry
doi 10.3389/fgeoc.2026.1919883
Original Research
Published
Downstream evaluation of synthetic AI-generated T 1 -weighted contrast-enhanced MR images in glioma segmentation and grading
Dimosthenis E. Gkotsis · Adam J. Schwarz · Jan Wolber · Lehel M. Ferenczi · Hongxu Yang
Frontiers in Radiology
doi 10.3389/fradi.2026.1931738
Original Research
Published
Neuro-psycho MMSig: multimodal mechanism enrichment platform for neuropsychiatric disorders
Vinay Srinivas Bharadhwaj · Karim S. Shalaby · Sathvik Guru Rao · Bruce Schultz · Jiayuan Zhang · Daniel Domingo-Fernández · Martin Hofmann-Apitius · Alpha Tom Kodamullil
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1898607
Original Research
Published
Structurally restricted message-passing within shallow architectures for explainable network-level brain decoding on small cohorts
José Diogo Marques dos Santos · Maria Beatriz Ramos · Luís Paulo Reis · José Paulo Marques dos Santos · Bruno Direito
Frontiers in Behavioral Neuroscience
doi 10.3389/fnbeh.2026.1833995
Original Research
Published
Beyond segmentation accuracy: understanding model reliability and failure modes in ultrasound image analysis
Agathe Bricout · David Hardman · Scott Inglis · Stephen Pye · Carmel M. Moran
Frontiers in Medical Technology
doi 10.3389/fmedt.2026.1918432
Original Research
Published
Experimental evaluation of compression algorithms for memory-constrained embedded systems
Tomáš Bača · Lukáš Formanek · Peter Ševčík · Ondrej Karpiš
Frontiers in Computer Science
doi 10.3389/fcomp.2026.1925314
Original Research
Published
A context-aware and human-centered framework for road safety assessment using semantic scene understanding
Imad Tbaileh · Ahmed Radwan · Oroob Yaseen · Mohammed Elhenawy · Huthaifa I. Ashqar · Rashed Isam Ashqar
Frontiers in Future Transportation
doi 10.3389/ffutr.2026.1920858
Original Research
Published
An AI-based blockchain framework with AES–RSA hybrid encryption for secure data sharing in smart environments
Sahbaa AbdulKareem Al-Abassy
Frontiers in Blockchain
doi 10.3389/fbloc.2026.1935632
Original Research
Published
An XGBoost–logistic regression hybrid stacking model for breast cancer outcome prediction
Oyetayo Oyebisi · Winnie Chacha · Femi Amoyedo
Frontiers in Applied Mathematics and Statistics
doi 10.3389/fams.2026.1931146
Original Research
Published
Plasma untargeted metabolomics reveals metabolic signatures associated with epilepsy and anti-seizure medication responsiveness
Zijian Li · Zhen Liang · Juan Ren · Songyan Liu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1885513
Original Research
Published
Integrative oxidative stress–disulfidptosis analysis identifies NPR3 and ZNF366 as cell-type-associated candidate markers in clear cell renal cell carcinoma
Ping Wang · Zhixuan Cai · Gaofeng Wu · Guangfeng Zhu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1912537
Original Research
Published
Multi-omics integration in allergy, viral infections and asthma: a comprehensive analysis of bioinformatics tools
Silvia Garcés Rigol · Nuria Contreras · Rafael Núñez · Elena Izquierdo · Domingo Barber · Alma Villaseñor · Osvaldo Graña Castro · María M. Escribese
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1904588
Mini Review
Published
Primary cilia as a molecular convergence hub linking neurodevelopment and autism spectrum disorder
Arianna Boscato · Lorenzo Milesi · Marta Biagioli · Alice Tata
Frontiers in Cellular Neuroscience
doi 10.3389/fncel.2026.1914796
Correction
Published
Correction: Establishing reference points for artificial social agent evaluation: the ASAQ representative set 2025
Siska Fitrianie · Amal Abdulrahman · Merijn Bruijnes · Willem-Paul Brinkman
Frontiers in Computer Science
doi 10.3389/fcomp.2026.1951219
Original Research
Published
AI-Accelerated blockchain architecture for efficient and secure electronic healthcare record exchange
Nagaraj Segar · Vijayarajan Vijayan
Frontiers in Blockchain
doi 10.3389/fbloc.2026.1905158
Original Research
Published
Decentralized blockchain governance for explainable causal AI in macroeconomic forecasting
Oumaima Abouzaid · Faouzi Boussedra
Frontiers in Blockchain
doi 10.3389/fbloc.2026.1883639
Original Research
Published
Integrated microarray-based and single-cell transcriptomic analyses reveal cell adhesion-related fibrotic remodeling signatures in heart failure
Shun Zhang · Le Li · Zuohua Li · Xiaojun Wang · Juan Zhou · Qing Lyu
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2026.1929610
Original Research
Published
Affordance-based robot manipulation with flow matching
Fan Zhang · Michael Gienger
Frontiers in Robotics and AI
doi 10.3389/frobt.2026.1906861
Brief Research Report
Published
New perspectives on nutritional stress—first carbon and nitrogen stable isotopes of pig remains from historic starvation experiments
Felix Sadebeck · Stuart Black · Renate Schafberg · Juliette Waterman
Frontiers in Environmental Archaeology
doi 10.3389/fearc.2026.1892726
Original Research
Published
A machine learning framework for interpreting phylogenetic tree patterns in interkingdom horizontal gene transfer
Kevin Aguirre-Carvajal · Cristian R. Munteanu · Vinicio Armijos-Jaramillo
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1891949
Original Research
Published
A single-cell atlas and Shiny-based framework for murine lung injury and remodeling
Qiuming Wang · Jixian Li · Philip J. Moos · Alessandro Venosa
Frontiers in Bioinformatics
doi 10.3389/fbinf.2026.1886929
Original Research
Published
Machine learning-based prediction of soil aggregate stability for sustainable land management in the eastern Himalayan region of India
Suryakant Gupta · Prachi Yadav · Jagabandhu Panda · Kiran Bala Behura · Subhankar Ghosh · Laishram Kanta Singh · Sougrakpam Roma Devi · Mainak Ghosh · Amulya Kumar Mohanty · Prasanta Kumar Pathak
Frontiers in Soil Science
doi 10.3389/fsoil.2026.1937878
Original Research
Published
Machine learning driven optimization of biofuel powered urban mobility for cleaner and smarter cities
Ritu Chauhan · Devanshi Thakur · Megat F. Zuhairi · Vivek Kumar Gaur
Frontiers in Sustainable Cities
doi 10.3389/frsc.2026.1906890
Original Research
Published
Forecasting pastoralist red meat production trajectories in a fragile and climate-vulnerable state: a comparative evaluation of classical, state-space, long-memory, and neural network models in Somalia
Abdirisak Osman Bade · Dahir Muse Shire · Saleban Mohamed Hassan · Abdisalam Hassan Muse
Pastoralism: Research, Policy and Practice
doi 10.3389/past.2026.17161
Original Research
Published
The application of deep neural networks to the detection of lumbar hernias: results from the approaches based on convolutional networks and transformers
António Fernandes · João Pedro Mazuco Rodriguez · Susana Moleirinho · Irina Trofimenko · Ekaterina Guseva · Alexander Martinovich · Ilzane Maria de Oliveira Morais · Louise Bisolo · Luís Mendes Gomes · José Machado
Frontiers in Radiology
doi 10.3389/fradi.2026.1722312
Original Research
Published
IndoorCART: a spatially-aware transformer framework for Wi-Fi fingerprinting indoor localization
Balaram Singh · Rajdeep Chatterjee · Mahendra Kumar Gourisaria · Manoj Sahni · Ernesto León-Castro
Frontiers in Signal Processing
doi 10.3389/frsip.2026.1884243
Systematic Review
Published
Forecasting sports outcomes through machine learning
Andres Gregori · Ivan Reyes-Pedroza · Ari Yair Barrera-Animas · Julieta Noguez · David Escobar-Castillejos
Frontiers in Computer Science
doi 10.3389/fcomp.2026.1883327
Review
Published
Performance, sustainability, and machine learning of UHPC with coarse aggregates: a critical review
S. K. Madhumitha · A. Abdul Rahim
Frontiers in Built Environment
doi 10.3389/fbuil.2026.1903555
Original Research
Published
The capturing ionospheric coupling and dynamic aurora (CICADA) nanosatellite mission concept
David M. Miles · Aroh Barjatya · Scott R. Bounds · Ivar W. Christopher · Jeffrey S. Dolan · Richard Dvorsky · Connor A. Feltman · Matthew G. Finley · Katherine Goodrich · Christian Hansen · Garret Hinson · Samuel Hisel · Gregory G. Howes · Allison N. Jaynes · Amanda M. Lasko · Gabriel Martin · Katherine J. Morris · Chris Piker · Carol Preston · Kevin L. Steele · Antonio Washington
Frontiers in Astronomy and Space Sciences
doi 10.3389/fspas.2026.1913241
Original Research
Published
A subject-specific mechanistic model of affect links electroencephalography, cardiorespiratory feedback, and monoaminergic dynamics
Masami Iwamoto
Frontiers in Computational Neuroscience
doi 10.3389/fncom.2026.1875657
Systematic Review
Published
Predictive accuracy of peptide–target interaction models in drug discovery: a systematic review and meta-analysis
William J. Waldock · Ahmad Guni · Ara Darzi · Cesar de la Fuente-Nunez · Hutan Ashrafian
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1894745
Brief Research Report
Published
Assessment of microexon-associated junction usage in Parkinson’s disease and spinocerebellar Ataxia type 3
Kira Mehnert · Jeannette Hübener-Schmid · Jakob Admard · Vladislav Lysenkov · German Demidov · Chrisovalantou Huridou · Jonasz Jeremiasz Weber · Olaf Riess · Nicolas Casadei
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2026.1872346
Original Research
Published
Soil and Water Assessment Tool reveals dominant baseflow in semi-arid catchment with sand dams in Kenya
Jana Reichenbach · Andreas Braun · Volker Hochschild
Frontiers in Water
doi 10.3389/frwa.2026.1922866
Original Research
Published
The association of extreme heat and PM 2.5 with preterm birth and low birthweight in Florida, United States
Jessica A. Broach · Emily W. Harville · Jihoon Jung · David Hsu · Xiuling Zhao · Yoonjung Ahn · Daniel Tong · Siqi Ma · Christopher K. Uejio
Frontiers in Environmental Health
doi 10.3389/fenvh.2026.1874291
Original Research
Published
Infant mortality across EU health systems: heterogeneity encoding, fixed effects regression, and machine learning in a small macro panel
Ecmel Kisa · Adnan Kisa
Frontiers in Health Services
doi 10.3389/frhs.2026.1893109
Original Research
Published
PDSA-DBUNet: dual-branch U-Net for abdominal medical image segmentation driven by polynomial dynamic sparse attention
Jiatong Shang · Guolin He · Xuyang Li
Frontiers in Signal Processing
doi 10.3389/frsip.2026.1904505
Original Research
Published
Evaluating large language models for domain-specific scholarly metadata classification
Muhammad Haris · Maryam Badar
Frontiers in Research Metrics and Analytics
doi 10.3389/frma.2026.1882130