Review
Published
Beyond GLP-1: underexplored peptide–receptor systems as the next frontier in drug discovery
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1792418
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Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 279 articles
Review
Published
A registry-based systematic review of lifestyle and non-pharmaceutical oncology interventions in Africa
Monica Wangari · Eunice Njoroge · Grace Mburu · Brenda Mogeni · Luke Ouma
Frontiers in Cancer Control and Society
doi 10.3389/fcacs.2026.1571038
Original Research
Published
Complications and treatment patterns in patients with non-transfusion-dependent α- and β-thalassemia compared with matched controls: a retrospective observational study using administrative claims data in the United States
Arielle L. Langer · Amey Rane · Keely S. Gilroy · Jing Zhao · Louise Lombard · Carolyn R. Lew · Sujit Sheth
Frontiers in Hematology
doi 10.3389/frhem.2026.1770034
Original Research
Published
Dose optimization of inhaled tigecycline in humans to overcome inherent adverse events and maximize bacterial clearance using a physiologically-based pharmacokinetic modeling approach
Hyunseo Park · Amarinder Singh · Ashish Srivastava · Bhargavi Thalluri · Christelle J. Mathieu · Paridhi Gupta · Camron M. Pearce · Malik Zohaib Ali · Ilham M. Alshiraihi · Sara E. Maloney Norcross · Anthony J. Hickey · Mercedes Gonzalez-Juarrero · Bernd Meibohm
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1762713
Review
Published
Food-derived molecules as regulators of intestinal tight junctions and barrier function: mechanisms and implications
Sinéad M. Ryan · David J. Brayden
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1692219
Original Research
Published
Towards a standardized diabetic prolonged wound healing model in hairless SKH1 mice
Elle Koivunotko · Julia Monola · Chris S. Pridgeon · Jere Linden · Riina Harjumäki · Emrah Yatkin · Mari Madetoja · Marjo Yliperttula
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10857
Original Research
Published
Ligand-directed assembly of an iminodiacetate-hybridized molybdenum-red isopolyoxomolybdate Mo V 10 Mo VI 3
Ingrid Gregorovic · Emir Al-Sayed · Nadiia I. Gumerova · Judith Füllborn-Ott · Ingo Ott · Gerald Giester · Annette Rompel
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1770808
Original Research
Published
Radiobiological evaluation of the therapeutic effect of silver-111 for the ISOLPHARM project
Alberto Arzenton · Aurora Leso · Francesca Rana · Giulia S. Valli · Elena Delgrosso · Laura Cansolino · Cinzia Ferrari · Silva Bortolussi · Isabella Guardamagna · Giorgio Baiocco · Giorgio Grosso · Davide Serafini · Andrea Gandini · Valerio Di Marco · Antonietta Donzella · Emilio Mariotti · Marcello Lunardon · Devid Maniglio · Germano Bonomi · Alberto Andrighetto
Frontiers in Nuclear Medicine
doi 10.3389/fnume.2026.1773638
Original Research
Published
A case study on N-nitrosamine investigation in a marketed drug: from analytical procedure validation to risk mitigation decision
Yue Zhang · Sabah Houari · Thomas Van Laethem · Priyanka Kumari · Eric Ziemons · Philippe Hubert · Cédric Hubert
Frontiers in Analytical Science
doi 10.3389/frans.2026.1772719
Original Research
Published
Low dose thirdhand smoke exposure enhances platelet functional responses in mice
Precious O. Badejo · Ahmed B. Alarabi · Hamdy E. A. Ali · Lanam Millican · Reina De La Paz · Shelby S. Umphres · Sadia Kamal · Fatima Z. Alshbool · Fadi T. Khasawneh
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10679
Original Research
Published
Synergistic removal of various emergent pollutants in biochar-enhanced constructed wetlands: a pilot-scale nature-based solution for municipal wastewater treatment improvements
Chaimae Maldou · Yasmina El Janoussi · Dhafer Mohammed M. Al Salah · Majida Lahrouni · Naaila Ouazzani · Tonni Agustiono Kurnaiwan · Ayoub El Ghadraoui · Amine Elleuch · Aroua Ammar · John Poté · Faissal Aziz
Frontiers in Environmental Chemistry
doi 10.3389/fenvc.2026.1762724
Review
Published
IDRs in Cross-Membrane Transport: Regulation of Ion Channels and Transporters, Mechanistic Studies Made Possible by NMR and Computational Methods
Olga Vinogradova
Frontiers in Biophysics
doi 10.3389/frbis.2026.1804302
Original Research
Published
The database of peptide medications for human deep-space missions demonstrates the potential for on-demand “Astropharmacy”
Rebecca C. Blum · Dorra Omrani · Alina Kunitskaya · Jessica E. Snyder · Cynthia Bui · Philip M. Williams · David J. Loftus · Lynn J. Rothschild
Frontiers in Space Technologies
doi 10.3389/frspt.2025.1692554
Original Research
Published
Colour of medicines and children’s acceptability: What children think of the colour of oral dosage forms?
Elisa Alessandrini · Sveinbjorn Gizurarson · Jennifer Walsh · Roy Turner · Daniel Schaufelberger · Sonia Iurian · Hannah Batchelor · Sandra Klein · Begonya Nafria · Pamela Dicks · Segolene Gaillard · Axel R. Franz · Jasmin Albano · Aleksander Wisniewski · Charlotte Vermehren · Christina Gade · Jon Traerup Andersen · Catherine Tuleu
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1744120
Original Research
Published
Chronic low back pain management in rural Cameroon: a pragmatic pilot study of osteopathic care, physiotherapy, and the “unique practitioner syndrome”
Ibrahim Npochinto Moumeni · Abdel-Nasser Njikam Moumeni · Tchuidjio Ketchogue Bristher Orlsiter · Fausting Atemkeng-Tsatedem
Frontiers in Musculoskeletal Disorders
doi 10.3389/fmscd.2025.1716794
Original Research
Published
The use of QbD for the development and validation of a stability-indicating RP-HPLC method for the quantitation of nevirapine in bulk, tablet and niosome formulations
Bwalya A. Witika · Roderick B. Walker
Frontiers in Analytical Science
doi 10.3389/frans.2026.1735125
Systematic Review
Published
Aerospace health: a systematic review and current state of science
Michael Joseph Dino · Chloe Margalaux Villafuerte · Justin Pimentel · Jerald Sayat · Joseph Carlo Vital · Danny Hernandez · Ladda Thiamwong · Veronica Decker · Mona Shattell · Luis Ezra Cruz · Mary Leoncio · Joshua Rejs Reyes · Reylan David · Jose Arnel Manalili
Frontiers in Space Technologies
doi 10.3389/frspt.2026.1736627
Review
Published
Current status of antimicrobial resistance in Indian healthcare system: combating antimicrobial resistance with precision medicine
Ashish Shinde · Athira Mohan · Vani Mahathi Bulusu · Poonam Soni · Jitendra Singh · Sagar Khadanga · Ankur Joshi · Poongothai Venkatachalapathy · Rupinder Kaur Kanwar · Sonal Sekhar Miraj · Murali Munisamy
Frontiers in Antibiotics
doi 10.3389/frabi.2026.1632790
Original Research
Published
Isolation, purification, and structural characterization of biosurfactants derived from indigenous probiotics Lactobacillus helveticus MTCC5463 and Lactobacillus rhamnosus MTCC5462
Kamini Pandey · Madhu Kumari · Sameena Mehtab · Barkha Singhal
Frontiers in Bacteriology
doi 10.3389/fbrio.2025.1726048
Original Research
Published
Kinetic insights into Ag-doped TiO 2 photocatalysts for dye degradation: advances in materials driving renewable energy technologies
Imad Ud Din · Laila Saad · Zia Ur Rehman · Fazal Suhrab Gul · Najeeb Ur Rehman · Fazal Mabood · Adnan Shahzad · Penggang Wang · Sameerah I. Al-Saeedi · Magdi E. A. Zaki
Frontiers in Catalysis
doi 10.3389/fctls.2025.1710435
Original Research
Published
Morphological and transcriptomic change of brain pericytes by lipopolysaccharide treatment
Taiki Asai · Yoshino Yonezu · Akiko Uyeda · Haruki Watanabe · Tatsunori Suzuki · Hidemi Misawa · Rieko Muramatsu
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1725431
Original Research
Published
Targeting F2R/PAR1 with ligand decorated lipid nanocarriers for enhanced drug delivery into ovarian cancer cells
Riya Khetan · Weranga Rajapaksha · Bukuru D. Nturubika · Todd A. Gillam · Doug A. Brooks · Sanjay Garg · Anton Blencowe · Hugo Albrecht · Preethi Eldi
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1727958
Review
Published
Receptor-targeted technetium-99m radiopharmaceuticals: increasing access to molecular imaging in healthcare
Michelle T. Ma
Frontiers in Chemical Biology
doi 10.3389/fchbi.2025.1729615
Original Research
Published
Development of a comprehensive approach for the characterization of polar plant decoctions by orthogonal LC-MS reversed phase, HILIC, and NMR metabolite profiling: the case of Combretum micranthum
Lisa Vuadens · Robin Huber · Laurence Marcourt · Luis-Manuel Quiros-Guerrero · Olivier Auguste Kirchhoffer · Arnaud Gaudry · Renata Campos Nogueira · Elhadji Assane Diop · Sidi Mohamed Seck · Jean-Luc Wolfender · Emerson Ferreira Queiroz
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1717575
Review
Published
Emerging micropollutants: risks, regulatory trends, and adsorption based-magnetic nanotechnology solutions
Amina Mumtaz · Saul Santini · Martin Albino · Beatrice Muzzi · Cristian Marinelli · Alessandra Cincinelli · Claudio Sangregorio · Tania Martellini
Frontiers in Environmental Chemistry
doi 10.3389/fenvc.2025.1675784
Original Research
Published
Novel prospectives of shikimic acid and Prunus mume extract for enhancing bioactivity on 5α-reductase and stability in cosmetic patches for acne treatment
Elizaveta Patronova · Egor Ilin · Viktor Filatov · Elena Kalenikova
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1737986
Mini Review
Published
Advances in genetic tools for metabolic engineering of non-conventional yeasts
Thasneem Banu Frousnoon · Stephen Mondo · Yasuo Yoshikuni
Frontiers in Synthetic Biology
doi 10.3389/fsybi.2025.1729790
Perspective
Published
Enabling living in space through modern innovations in space medicine: a perspective on tissue-on-a-chip technology
Subhajit Hazra · Sibsankar Palit · Thais Russomano · Gaurab Ghosh · Polash Sannigrahi
Frontiers in Space Technologies
doi 10.3389/frspt.2025.1725575
Original Research
Published
Activated carbon sheets from pomegranate peel with ionic liquid for Knoevenagel condensation: synthesis of aryledene and xanthene derivatives
Dhaneshwar Prasad · Archana Asatkar · Swetlana Prerna Ram · Shripal Singh · Santosh Kumar Prajapati · Subhash Banerjee
Frontiers in Catalysis
doi 10.3389/fctls.2025.1721217
Original Research
Published
Radiolabeled para -I-nimesulide: an unexpected tracer for imaging peripheral inflammation
Yumi Yamamoto · Kentaro Imai · Yohei Saito · Fumihiko Yamamoto
Frontiers in Nuclear Medicine
doi 10.3389/fnume.2025.1720380
Original Research
Published
Cohort event monitoring of booster COVID-19 vaccine safety using patient-reported outcomes in pregnant women
Emeline Maisonneuve · Nicoletta Luxi · Chiara Bellitto · Francesco Ciccimarra · Monika Raethke · Florence van Hunsel · Thomas Lieber · Erik Mulder · Fabio Riefolo · Felipe Villalobos · Nicolas H. Thurin · Francisco Batel-Marques · Kathryn Morton · Fergal O'Shaughnessy · Brian Cleary · Simona Sonderlichová · Andreea Farcas · Camelia Bucsa · Guillaume Favre · Satu J. Siiskonen · David Baud · Miriam C. J. M. Sturkenboom · Gianluca Trifirò · Alice Panchaud
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2025.1689349
Original Research
Published
The influence of dioleoylphosphatidylcholine (DOPC) on the lipid sponge phase system
Marshall R. Machingauta · Aina McEvoy · Alma Karlsson · Justas Barauskas · Tommy Nylander · Jennifer Gilbert
Frontiers in Soft Matter
doi 10.3389/frsfm.2025.1708264
Review
Published
A narrative review on the environmental impact of medicines: from water analysis and in vivo studies to prescribing appropriateness, based on European and Italian legal frameworks
Irene Cristini · Elisabetta Poluzzi · Federica Soardo · Salvatore Crisafulli · Stefano Polesello · Ursula Kirchmayer · Marco Milani · Francesca Russo · Michele Nicoletti · Giovanna Scroccaro · Paola Deambrosis · Shima Tavakolian Haghighi · Jacopo Grisotto · Ugo Moretti · Giovanna Paolone · Gianluca Trifirò
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2025.1681648
Review
Published
Pharmacovigilance and bioethics: the importance of a neglected relationship
Giuseppe Alvaro · Michael Müller · Richa Chhibber · Robert Fuentes
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2025.1698515
Original Research
Published
Mechanics-guided parametric modeling of intranasal spray devices and formulations for targeted drug delivery to the nasopharynx
Md Tariqul Hossain · Abir Malakar · Mohammad Yeasin · William O’Connell · Mohammad Mehedi Hasan Akash · Azadeh A. T. Borojeni · Devranjan Samanta · Gerallt Williams · Joshua Reineke · Gonçalo Farias · Sunghwan Jung · Julie Suman · Saikat Basu
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1721960
Original Research
Published
Automated radiosynthesis and clinical experience of [ 18 F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study
Peerapon Kiatkittikul · Pradith Lerdsirisuk · Laksika Bhuthathorn · Arthita Choolam · Attapon Jantarato · Pattanapong Kongsakorn · Wisakha Chintawan · Thanapon Sringam · Nirawan Fonghoi · Saiphet Vanprom · Ryuichi Harada · Nobuyuki Okamura · Shozo Furumoto · Chetsadaporn Promteangtrong
Frontiers in Nuclear Medicine
doi 10.3389/fnume.2025.1718255
Review
Published
Discrepancies in regulations in post-marketing safety surveillance of drug-device combination products in the EU and US: a review
Joan D’souza · Mukesh Nandave · Ruth Blöchlinger
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2025.1609455
Perspective
Published
The role of MedDRA in global pharmacovigilance and public health during COVID-19: pandemic preparedness and response
Brian O’Hare · Heba Ibrahim · Patrick Revelle
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2025.1607642
Brief Research Report
Published
First positronium lifetime imaging with scandium-44 on a long axial field-of-view PET/CT
Lorenzo Mercolli · William M. Steinberger · Pascal V. Grundler · Anzhelika Moiseeva · Saverio Braccini · Maurizio Conti · Paweł Moskal · Narendra Rathod · Axel Rominger · Hasan Sari · Roger Schibli · Robert Seifert · Kuangyu Shi · Ewa Ł. Stepień · Nicholas P. van der Meulen
Frontiers in Nuclear Medicine
doi 10.3389/fnume.2025.1648621
Original Research
Published
Network pharmacology-based strategy and phytochemical screening of antioxidants suggesting the potential anti-obesity relevance of soybean food bars
Tedi Rustandi · Fakhriah Hayati · Fatah Nugroho · Senya Puteri Amalia · Regina Nastasya · Ahmed Mahal
Frontiers in Natural Products
doi 10.3389/fntpr.2025.1694933
Sensors
Published
Electrooxidation of dopamine using MoS 2 -Ag conductive ink on screen-printed electrodes for electrochemical sensing
Ntsoaki Mphuthi · Lucky Mashudu Sikwhivhilu · Suprakas Sinha Ray · Bulelwa Ntsendwana
Frontiers in Sensors
doi 10.3389/fsens.2025.1650004
Drug Safety and Regulation
Published
Communicating medication risks in pregnancy: Towards shared decision making
Ursula Winterfeld · Kenneth Hodson · Maya Berlin · Benoît Marin · Michael Ceulemans · Corinna Weber-Schoendorfer · François R. Girardin · David Baud · Béatrice Schaad · Alice Panchaud
Frontiers in Drug Safety and Regulation
doi 10.3389/fdsfr.2025.1712216
Nuclear Medicine
Published
Population pharmacokinetic modeling in radiopharmaceutical therapy: a review
Deni Hardiansyah · Bisma Barron Patrianesha · Gerhard Glatting
Frontiers in Nuclear Medicine
doi 10.3389/fnume.2025.1695332
Synthetic Biology
Published
Frontiers in biofoundry: opportunities and challenges
Choo Yee Yu · Geik Yong Ang · Nurulfiza Mat Isa · Kok-Gan Chan
Frontiers in Synthetic Biology
doi 10.3389/fsybi.2025.1630026
Environmental Chemistry
Published
Squalene recovery from Uzen oil field wastewater: a novel abiotic resource
Yerlan M. Suleimen · Alexander N. Trofimov · Gulnur K. Mamytbekova · Dilnaz Kurbanaliyeva · Burkitkan Akbay · Tursonjan Tokay
Frontiers in Environmental Chemistry
doi 10.3389/fenvc.2025.1672872
Science archive
Published
Synergistic combination of cannabidiol and celecoxib or 2,5-dimethylcelecoxib exerts oxidative stress-mediated cytotoxicity and mitigates glioblastoma invasiveness
Anna Rybarczyk · Aleksandra Majchrzak-Celińska · Violetta Krajka-Kuźniak
Acta Biochimica Polonica
doi 10.3389/abp.2025.15062
Catalysis
Published
Ag-Fe 2 O 3 nanohybrids for photocatalytic degradation and antibacterial activity
Asaad AlZubaidi · Vikram Pandit · Vivekanand Jawale · Madhu Gupta · Dattatray Late
Frontiers in Catalysis
doi 10.3389/fctls.2025.1655324
Nuclear Medicine
Published
Platinum group metals for nuclear medicine, a luxurious dream or the future of imaging and therapy: a review
Daniel G. Racz · Ivis F. Chaple
Frontiers in Nuclear Medicine
doi 10.3389/fnume.2025.1656374