Original ResearchPublished 9 October 2026Distinct temporal trajectories of EPAS1 mRNA expression during moderate-altitude training in Han and Tibetan endurance athletesQing-Qing Su · Hai-Lin Ma · Yan-Lin Sun · Fu-Hai Ma · Yan-Chang Shen · Jian Wang · Xiao-Wei Ma · Jiang-Long Zhang · Yang Zhang · Erik R. SwensonFrontiers in Cell and Developmental Biologydoi 10.3389/fcell.2026.1973797
Original ResearchPublished 9 October 2026Single cell RNA-seq analysis identifies junctional adhesion molecule two positive endothelial cells aggravate osteoarthritis by mediating vascular permeability and macrophage adhesionYang Xing · Chengxin Li · Chao Wang · Linli Zheng · Puyi ShengFrontiers in Cell and Developmental Biologydoi 10.3389/fcell.2026.1937741
Mini ReviewPublished 9 October 2026Phytogenic zinc oxide nanoparticles in breast cancer therapy: an ethnopharmacological perspective on multi-targeted mechanistic pathways and translational constraintsDhanya Soman Pillai · Ramesh Narve Venkatesha · Amarnath Karavettekudy Ranjit · Zeena Subramonia PillaiFrontiers in Pharmacologydoi 10.3389/fphar.2026.1883009
Original ResearchPublished 9 October 2026Tirzepatide versus other glucose-lowering therapies and risk of COPD exacerbations in patients with comorbid type 2 diabetes: a retrospective cohort studyWan-Hsuan Hsu · Yang-En Chan · Jheng-Yan Wu · Yao-Ming Chuang · Chia-Yu Kuo · Bo-Wen Shiau · Po-Yu Huang · Chih-Cheng LaiFrontiers in Pharmacologydoi 10.3389/fphar.2026.1917340
Original ResearchPublished 9 October 2026A novel CAF-related gene signature for prognostic and immunotherapy response prediction in PDAC based on single-cell RNA-seq and bulk RNA-seq dataXuezhi Du · Zesheng Li · Yuwei Wang · Lei Han · Jinjin Sun · Weipeng GongFrontiers in Pharmacologydoi 10.3389/fphar.2026.1873756
ReviewPublished 9 October 2026Pharmacological regulation of chondrocyte ferroptosis by plant-derived metabolites in osteoarthritis: from molecular mechanisms to targeted nanodeliveryTianci Guo · Qi Liu · Jida Wang · Keming Ren · Longyao Zhang · Jinzhong Sheng · Aifeng LiuFrontiers in Pharmacologydoi 10.3389/fphar.2026.1949976
Original ResearchPublished 9 October 2026Cannabidiol preserves astrocyte viability and attenuates injury-induced glial stress responses across zebra finch song control nucleiDylan A. Marshall · Karen A. Litwa · Ken SoderstromFrontiers in Pharmacologydoi 10.3389/fphar.2026.1972787
Original ResearchPublished 9 October 2026Multi-source data integration and ensemble machine learning analysis of the role of Corilagin in regulating endoplasmic reticulum stress and alleviating intestinal ischemia reperfusion injury in miceZhiyang Wang · Qin Han · Lijie Pang · Siyang Zheng · Xin Wang · Bin Tian · Kun Li · Bin Li · Feng Qiu · Yunpeng Diao · Ruqiang YuanFrontiers in Pharmacologydoi 10.3389/fphar.2026.1966534
Original ResearchPublished 9 October 2026Histopathology-guided spatial transcriptomic analysis identifies an ECM-associated stromal pattern in lacrimal gland adenoid cystic carcinoma with complementary proteomic and functional analysesRong Luan · Difei Zuo · Yeqing Wang · Meixia Jiang · Xun Liu · Limin Zhu · Tingting LinFrontiers in Pharmacologydoi 10.3389/fphar.2026.1949721
Original ResearchPublished 9 October 2026Knockdown of vATPase subunit A impairs larval-pupal development in Plutella xylostellaXuetao Yu · Yanan Jiang · Lijie Ren · Jinhua Luo · Zhanhao Dai · Lin Lu · Li Ren · Li Zhu · Chao Li · Qidi Wei · Gang Wu · Xiaohong Yan · Chenhui ShenFrontiers in Physiologydoi 10.3389/fphys.2026.1974591
Original ResearchPublished 9 October 2026A robust adversarial learning framework for EEG emotion recognitionHao Yang · Li Chen · Jianyong Gao · Junqiang Zhang · Jianfeng ZhangFrontiers in Neurologydoi 10.3389/fneur.2026.1951986
ReviewPublished 9 October 2026Periostin in diabetic kidney disease: mechanistic insights, biomarkers, and therapeutic perspectivesXuhao Li · Yamiao Wu · Yexuan Shi · Guoliang Xiong · Lingfei Lu · Jiandong LuFrontiers in Endocrinologydoi 10.3389/fendo.2026.1979232
Case ReportPublished 9 October 2026Case Report: Sustained pubertal suppression for 68 months with a single histrelin acetate implant in central precocious pubertySofya Ilmer · Parissa SalemiFrontiers in Endocrinologydoi 10.3389/fendo.2026.1951374
Original ResearchPublished 9 October 2026Effects of Latin dance exercise on body image and social anxiety in female college studentsLuyao Wang · Zhenzhen Li · Yiming Liu · Xutao LyuFrontiers in Psychologydoi 10.3389/fpsyg.2026.1958896
ReviewPublished 9 October 2026Epicardial adipose tissue in obesity-related heart failure with preserved ejection fraction and atrial fibrillation: mechanisms, imaging, and therapeutic modulationQi Zhu · Tiance Xu · Chen Yang · Lili TanFrontiers in Endocrinologydoi 10.3389/fendo.2026.1976969
Original ResearchPublished 9 October 2026Past wounds, present bonds, future mothers: item-level analysis of perinatal risk profilesRaffaella Mineo · Leonardo Fazio · Antonio Maiorana · Claudia Guarneri · Jada Sottile · Eleonora Bevacqua · Linda A. Antonucci · Maria Rita InfurnaFrontiers in Psychologydoi 10.3389/fpsyg.2026.1899047
Original ResearchPublished 9 October 2026Stage anxiety and piano performance: the sequential mediating roles of self-efficacy and attentional controlYue Sun · Zhou ZhouFrontiers in Psychologydoi 10.3389/fpsyg.2026.1895260
Systematic ReviewPublished 9 October 2026Network meta-analysis of the effects of traditional Chinese fitness exercises on mental health and physical benefits among college studentsNan Wang · Hao Hong · Maolin Dong · Yaoshu Li · Lisha Lan · Junjian ZhengFrontiers in Psychiatrydoi 10.3389/fpsyt.2026.1921373
Systematic ReviewPublished 9 October 2026Efficacy of artificial intelligence-driven conversational agents (chatbots) for mental health promotion among university students: a systematic review and meta-analysisChen Shao · Xiaochen Chen · Shengnan Qiao · Ang Li · Shipeng Liu · Yanglong ChenFrontiers in Psychiatrydoi 10.3389/fpsyt.2026.1824378
Original ResearchPublished 9 October 2026The relationship between impulsive behaviors and adult attention-deficit/hyperactivity disorder symptoms in bipolar disorderTülay Sati Kirkan · Nazan DolapogluFrontiers in Psychiatrydoi 10.3389/fpsyt.2026.1916550
ReviewPublished 9 October 2026Beyond the light-driven pacemaker: the suprachiasmatic nucleus as a dynamic coordinator of environmental cuesTao Zhang · Kai Huang · Jing Yu · Shaojun Wu · Qiaocheng ZhaiFrontiers in Neurosciencedoi 10.3389/fnins.2026.1937340
ReviewPublished 9 October 2026T-cell dynamics after intracerebral hemorrhage and stroke-associated pneumonia: the vicious cycle of the lung–brain axisJingyan Li · Wei NiFrontiers in Neurosciencedoi 10.3389/fnins.2026.1953214
Original ResearchPublished 8 October 2026Repeatability in venom expenditure during defensive bites in rattlesnakes: use of a chemical weapon deployed to generate an extended phenotypeChelsea E. Martin · William K. HayesFrontiers in Ethologydoi 10.3389/fetho.2026.1918065
Original ResearchPublished 8 October 2026Nutrient mass balance of koi–basil aquaponics production systemsNathan Howell · Behnam AskarianFrontiers in Aquaculturedoi 10.3389/faquc.2026.1914289
Original ResearchPublished 8 October 2026Energy and resource sustainability patterns in the European Union through clustering and convergence dynamicsNicoleta Barbuta-Misu · Puiu Lucian Georgescu · Monica Laura Zlati · Costinela Fortea · Valentin Marian AntohiFrontiers in Environmental Economicsdoi 10.3389/frevc.2026.1943790
Original ResearchPublished 8 October 2026Comparative long-term outcomes of kidney transplantation from donors with isolated microscopic hematuria and thin basement membrane disease versus donors with isolated microscopic hematuria and normal histology: the largest cohort analysis to dateYaser Shah · Dieter Broering · Dalia Obeid · Hassan Aleid · Ahmed Nazmi · Hani Alahdal · Kris Ann Hervera Marquez · Turki AlHussain · Tariq AliFrontiers in Transplantationdoi 10.3389/frtra.2026.1952224
ReviewPublished 8 October 2026Biophysical transport control in smart nanocomposite packaging under non-thermal food preservation technologiesAdeshina Fadeyibi · Azeez Ayinla Adebayo · Zinash Delebo Osunde · Mohammed Gana YisaFrontiers in Food Science and Technologydoi 10.3389/frfst.2026.1980752
Original ResearchPublished 8 October 2026Human-Hippopotamus conflicts and socio-ecological tensions in the Ruzizi plain: a one health and political ecology perspectiveEsther Mufungizi Ahana · Marie Shangalume Fadhili · François Mmunga Assumani · Christian Zagabe Muderhwa · Gustave Nachigera MushagalusaFrontiers in Conservation Sciencedoi 10.3389/fcosc.2026.1921310
Original ResearchPublished 8 October 2026Characterizing and mitigating protocol-dependent gene expression bias in 3′ and 5′ single-cell RNA sequencingValeryia Shydlouskaya · S. M. Mansour Haeryfar · Tallulah S. AndrewsFrontiers in Bioinformaticsdoi 10.3389/fbinf.2026.1931243
PerspectivePublished 8 October 2026From disease activity scores to precision medicine: biomarkers and composite models for risk stratification in chronic spontaneous urticariaShuayb Elkhalifa · Mohamed AbuzakoukFrontiers in Allergydoi 10.3389/falgy.2026.1962595
Mini ReviewPublished 8 October 2026Sleep and circadian disruption during human spaceflight: mechanisms, operational consequences, and countermeasuresMerel Goedegebure · Sarah BaatoutFrontiers in Space Technologiesdoi 10.3389/frspt.2026.1958668
Original ResearchPublished 8 October 2026Influenza A (H1N1)pdm infection exacerbates behavioral, cognitive, and synaptic impairments in 5xFAD miceAnastasiya Rakovskaya · Alexey Lozhkov · Valeria Tverdokhlebova · Yana Zabrodskaya · Egor Vinokurov · Valeria Kirenskaya · Alexander Erofeev · Angelika Garshinina · Valeria Zryacheva · Anna Shtro · Ekaterina Pchitskaya · Olga Vlasova · Ekaterina Elpaeva · Pavel Dav · Ilya Bezprozvanny · Andrey VasinFrontiers in Behavioral Neurosciencedoi 10.3389/fnbeh.2026.1955816
Study ProtocolPublished 8 October 2026Co-designing accessible digital mindfulness for veterans with spinal cord injury: protocol for developing and testing VA CALM-SCI for virtual realityHilary Touchett · Kathryn Kanzler · Zina Trost · Jan Lindsay · Felicia SkeltonFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1923501
PerspectivePublished 8 October 2026A prebill control plane for record integrity in inpatient artificial intelligence-enabled clinical documentation workflowsStephanie Smith · Hani JudehFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1910263
Systematic ReviewPublished 8 October 2026Beyond the app: a marketness assessment of digital health, sports, and well-being - a systematic reviewFrancisco von Hafe · Ana Rita Santos · Ana Rita Londral · Ana Margarida Silva · José Lopes · Nuno Carvalho · Soraia Ferreira · Salomé AzevedoFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1871114
Original ResearchPublished 8 October 2026Differential sparse attention framework for accurate ovarian cancer subtype classification using DenseNet121Muhammad Shoaib Saleem · Javed Rashid · Turke Althobaiti · Faiza Jameel · Khiati Zakaria · Hari Mohan Rai · Anwar GhaniFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1875306
Original ResearchPublished 8 October 2026Multimodal classification of skin lesions based on lightweight gated low-rank hyper-fusion networkKe Wang · Tao Zhang · Xingqi Liu · Jiancun Zhou · Qian He · Jianxin HeFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1947161
Brief Research ReportPublished 8 October 2026Sex-based diagnostic bias in AI symptom checkers: a structured, exploratory audit of three platformsSamah Khan · Michael K. Paasche-OrlowFrontiers in Digital Healthdoi 10.3389/fdgth.2026.1950777
Policy and Practice ReviewsPublished 8 October 2026Municipal solid waste management systems in Nelson Mandela Bay Municipality: a comparative analysis across diverse income groupsSibongangani Khonelihle MngomezuluFrontiers in Sustainabilitydoi 10.3389/frsus.2026.1941833
Original ResearchPublished 8 October 2026Assessment of the transcriptional and cellular effects of CRISPRa targeting Dopa decarboxylase and GTP cyclohydrolase 1 in HEK293 and SH-SY5Y cellular models of Parkinsonian neurotoxicitySiyethaba Zinhle Bhengu · Ravesh Singh · Veron Ramsuran · Zama Ndlondlo Princess MsibiFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.1883789
Mini ReviewPublished 8 October 2026Cortical circuits linking peripheral inflammation to affective statesDahae J. Jun · Shi Tang · Emilia FavuzziFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.1951226
Original ResearchPublished 8 October 2026Association between injury severity and recovery of objective functional measures following adolescent lateral ankle sprain: a secondary cohort analysisMatas Meškauskas · Saulius Rutkauskas · Miglė Misiūnienė · Jūratė Tomkevičiūtė · Paulina Kriauzaitė · Dalius Malcius · Emilis ČekanauskasFrontiers in Sports and Active Livingdoi 10.3389/fspor.2026.1966025
Original ResearchPublished 8 October 2026Effects of a physically active gamification program on cognitive function in primary school childrenMaría del Carmen Carcelén-Fraile · Amanda Camacho-Illana · Alba Rusillo-Magdaleno · Alberto Ruiz-ArizaFrontiers in Sports and Active Livingdoi 10.3389/fspor.2026.1967341
Original ResearchPublished 8 October 2026The role of ferro-aging genes in periodontitis: novel insights based on bioinformatics analysisPoyi Chu · Danhua Wu · Jianwen Deng · XuFeng ChenFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1875267
Original ResearchPublished 8 October 2026A RIPK2-associated macrophage program links mycobacterial sensing to osteoclastogenesis in bone tuberculosisYuyang Zhang · Ziyang Zhang · Dongyang Zhang · Jiulin Tan · Zhaoxin Ma · Qingyang Xiao · Jie Zhang · Qixiu Yu · Zehua Zhang · Yong Tang · Ce Dou · Fei LuoFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1970405
Original ResearchPublished 8 October 2026Regulatory role and mechanism of sRNA24 targeting pqsH in Pseudomonas aeruginosa infection immunityHuanlan Liao · Qianying Liu · Yuyang Liu · Qiwei Li · Yujuan Xiong · Lan Wang · Yang LuFrontiers in Cellular and Infection Microbiologydoi 10.3389/fcimb.2026.1933779
Original ResearchPublished 8 October 2026GenAI literacy and online learning resilience among Chinese university students: the mediating role of self-efficacyDinara Dauyen · Ulzhan ZhubaniyazovaFrontiers in Educationdoi 10.3389/feduc.2026.1860024
Original ResearchPublished 8 October 2026Unequal coexistence: governance lock-in among academic mission logics in a multidisciplinary facultyBernt Arne BertheussenFrontiers in Educationdoi 10.3389/feduc.2026.1917314