Review
Published
Neuro-regulatory drug discovery (NRGDD): a neural-circuit framework for systemic therapeutic modulation
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1782364
Library
Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 318 articles
Original Research
Published
Are community-delivered patient navigation interventions the answer for targeting colorectal cancer screening inequalities? Findings from Lancashire's “Call for a KIT” intervention
Sandro Tiziano Stoffel · Shahida Hanif · Lorraine Morris · Robert Kerrison · Yasemin Hirst · Christian Von Wagner
Frontiers in Cancer Control and Society
doi 10.3389/fcacs.2026.1518293
Case Report
Published
Case Report: Neurological and pulmonary angiostrongylosis in a Ryukyu long-furred rat (Diplothrix legata) on Amami-Oshima Island, Japan
So Shinya · Toshihiro Tokiwa · Keita Sakashita · Hisashi Yoshimura · Ryotaro Suzuki · Ryouta Torimoto · Yukinori Muraoka · Masami Yamamoto
Frontiers in Parasitology
doi 10.3389/fpara.2026.1797945
Review
Published
A narrative review of motor control dual pathways: the corticospinal and reticulospinal tracts in synergy and differentiation
Yun Xing · Jiaxin Liu · Linrui Wu · Ke Zhang · Shengbo Yang
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1768036
Systematic Review
Published
Interventions Addressing Vaccine Hesitancy in the WHO European Region and in North America (United States and Canada): A Systematic Review
Flavia Pennisi · Carlo Lunetti · Chiara Barbati · Luca Viviani · Anna Carole D’Amelio · Anabela da Conceição Pereira · Tiago Correia · Anna Odone · Carlo Signorelli
Public Health Reviews
doi 10.3389/phrs.2026.1609375
Original Research
Published
Photo-triggered and magnetically guided nanosystems for precision drug transport: architecture development, spectral analysis and release behavior
Feng Liu · Xing Peng · Yinghong Ling · Weizhi Tan · Mengjiao Huang · Tieyu Chen · Xiaohu Qin
Frontiers in Nanotechnology
doi 10.3389/fnano.2026.1788494
Original Research
Published
Synergistic efficacy of combined neurolysis and methylcobalamin in peripheral nerve injury: a randomized clinical trial
Xuwei Hu · Zuoshi Li
Frontiers in Integrative Neuroscience
doi 10.3389/fnint.2026.1747898
Review
Published
Novel therapeutic approaches targeting biomechanical pathway alterations in bone diseases
Malkiet Kaur · Manju Nagpal
Frontiers in Biophysics
doi 10.3389/frbis.2026.1773451
Systematic Review
Published
Nanoparticle-mediated mRNA delivery for cancer, autoimmunity, and genetic diseases: a rapid review
Okechukwu Paul-Chima Ugwu · Fabian C. Ogenyi · Mariam Basajja · Chinyere N. Ugwu · Mundu M. Mustafa · Michael Ben Okon
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1793322
Review
Published
Revisiting old drugs and drug combinations for polycythemia vera and related neoplasms
Gökhan Mergen · Hans C. Hasselbalch
Frontiers in Hematology
doi 10.3389/frhem.2026.1749376
Original Research
Published
Cross-species gestural coding framework for social carnivores
Andrew J. Laurita · Stephanie A. Poindexter
Frontiers in Ethology
doi 10.3389/fetho.2026.1770290
Original Research
Published
Microbiota-derived succinic acid boosts antiviral activity of AKT targeting in coronaviruses
Hanhan Feng · Xiaofeng Liu · Nanping Wu
Frontiers in Virology
doi 10.3389/fviro.2026.1751938
Review
Published
Vernalization control in the Brassicaceae: a multidimensional translational landscape
Shuta Yano · Akhi Paul Chowdhury · Ayasha Akter · Ryo Fujimoto · Diana Mihaela Buzas · Kenji Osabe
Frontiers in Horticulture
doi 10.3389/fhort.2026.1791790
Original Research
Published
Global MyoG research 2004–2024: a bibliometric analysis of trends and translational implications
Luoming Hu · Weizhong Zhuang · Weimin Chen · Song Yang · Shuo Chen · Xin Wang · Qiang Gao · Jimei Chen
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10929
Original Research
Published
Metabolomics-guided identification of bioactive phytometabolites from South African plants targeting neuroblastoma
Mmei Cheryl Motshudi · Clarissa Marcelle Naidoo · Chikwelu Lawrence Obi · Benson Chucks Iweriebor · Earl Prinsloo · Muhammad Sulaiman Zubair · Nqobile Monate Mkolo
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10867
Original Research
Published
Ananalysis of the effects of Treg cell therapy intervention on the gut microbiota of type 1 diabetic mice using 16S rRNA gene sequencing
Mengyao Zhou · Kang Du · Hanmin Wang · Zhuxian Zhang · Rui Zhao · Chenghong Ma · Qionger Huang · Wei Zhang · Weiwen Chen
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10701
Review
Published
Skeletal muscle reprogramming in peripheral nerve injury: mechanisms, therapeutic roles, and complication management
Fuqiang Long · Xiaoru Pan · Anxin He · Xinlu Wang · Zairong Wei · Shaoying Gao
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10835
Review
Published
Overcoming Candida biofilm resistance: targeting persister cells with probiotic-derived metabolites
Priyanka Debta · Binaya Krushna Sahu · Sudipta Kumar Patra · Fakir Mohan Debta · Ekagrata Mishra · Sujogya Kumar Panda
Frontiers in Antibiotics
doi 10.3389/frabi.2026.1767028
Methods
Published
A novel methodology for localizing pallidal deep brain stimulation leads
Benjamin Pobiel · Kevin J. O’Neill · Remi Patriat · Tara Palnitkar · Meghan E. Hill · Rachel C. Cole · Henry Braun · Stephanie L. Alberico · Biswaranjan Mohanty · Devyn Bauer · Michael C. Park · Scott E. Cooper · Jerrold L. Vitek · Noam Harel · Joshua E. Aman
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1768558
Original Research
Published
Wavelength selection for laser design in mid-infrared spectroscopy
Miriam Aledda · Federico Marini · Bijay Kafle · Mehmet C. Erdem · Pranish Karki · Kristian H. Liland · Boris Zimmermann · Nils K. Afseth · Alessandra Biancolillo · Valeria Tafintseva · Kristin Tøndel · Volha Shapaval · Achim Kohler
Frontiers in Photonics
doi 10.3389/fphot.2026.1696425
Original Research
Published
Colour of medicines and children’s acceptability: What children think of the colour of oral dosage forms?
Elisa Alessandrini · Sveinbjorn Gizurarson · Jennifer Walsh · Roy Turner · Daniel Schaufelberger · Sonia Iurian · Hannah Batchelor · Sandra Klein · Begonya Nafria · Pamela Dicks · Segolene Gaillard · Axel R. Franz · Jasmin Albano · Aleksander Wisniewski · Charlotte Vermehren · Christina Gade · Jon Traerup Andersen · Catherine Tuleu
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1744120
Mini Review
Published
Enhanced information processing in the human neocortex: cellular mechanisms and translational perspectives
Manuela Tore · Laura Monni · Alessio Di Clemente · Michele Giugliano
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1770193
Original Research
Published
Ecological influences on host–parasite dynamics among Biomphalaria snails in two schistosomiasis endemic regions of Kenya
Florence N. Parsimei · Steven Ger Nyanjom · Mercy Y. Akinyi · George Ogara · Collins Ngudi · Patrick K. Karanja · Maurice R. Odiere · Lucy Ochola
Frontiers in Parasitology
doi 10.3389/fpara.2026.1729760
Review
Published
The impact of epigenetics on tumor metabolism: Friend or foe in drug response?
Serena Castelli · Melania Franchini · Luigi Ferraro · Nicolò Mangraviti
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1755829
Review
Published
Advances in endothelial cell targeting by AAV vectors
Milena Cichon · Alicja Jozkowicz · Anna Grochot-Przeczek
Acta Biochimica Polonica
doi 10.3389/abp.2026.15740
Original Research
Published
A next-generation strategy for HIV-1 vaccination: computational design of a multi-epitope subunit vaccine targeting global circulating variants
Sajid Khan · Zarlish Attique · Muhammad Hamza · Lingyu Li · Muhammad Imran · Li Yu · Suping Zhang
Frontiers in Virology
doi 10.3389/fviro.2025.1705632
Commentary
Published
Commentary: CVM-1118 (foslinanib), a 2-phenyl-4-quinolone derivative, promotes apoptosis and inhibits vasculogenic mimicry via targeting TRAP1
Mary J. C. Hendrix · Elisabeth A. Seftor · Richard E. B. Seftor · Yi-Wen Chu · Du-Shieng Chien · Yen-Ling Chen
Pathology and Oncology Research
doi 10.3389/pore.2026.1612325
Case Report
Published
Daratumumab in severe Evans syndrome: a case report
Stefan M. Hillmann · Hendrik Brockhoff · Sarah Loebel · Suna Hentschke · Dirk Arnold · Hans Salwender
Frontiers in Hematology
doi 10.3389/frhem.2025.1719208
Original Research
Published
Targeting F2R/PAR1 with ligand decorated lipid nanocarriers for enhanced drug delivery into ovarian cancer cells
Riya Khetan · Weranga Rajapaksha · Bukuru D. Nturubika · Todd A. Gillam · Doug A. Brooks · Sanjay Garg · Anton Blencowe · Hugo Albrecht · Preethi Eldi
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1727958
Review
Published
Research advances in neuronavigated target localization for repetitive transcranial magnetic stimulation in depression: from standardization to individualized neuromodulation
Luyang Jiang · Chris Chit Sze Fung · Calvin Pak Wing Cheng
Frontiers in Neuroimaging
doi 10.3389/fnimg.2025.1703198
Review
Published
RNA splicing in bone diseases: mechanisms, pathogenesis and therapeutics
Linlin Zheng · Hui Sun · Ning Li · Lianqing Wang · Tianchu Li · Qiaoli Zhai
Acta Biochimica Polonica
doi 10.3389/abp.2025.15819
Clinical Trial
Published
Automated thermo-mechanical therapy for immediate relief in chronic non-specific lower back pain: a randomized controlled trial
Kyle Donnery · Giuseppina Pilloni · Mohamad FallahRad · Kiwon Lee · Byungyun Han · Soonhi Park · Jihye Kim · Leigh Charvet · Marom Bikson
Frontiers in Neuroergonomics
doi 10.3389/fnrgo.2025.1674928
Review
Published
CRISPR/Cas9-based programmable genome editing in chickens: concepts, applications and regulatory issues
Gautham Kolluri · Adnan Naim · Shiva Kumar Kurva · Jagbir Singh Tyagi · Mohd. Matin Ansari · Simmi Tomar · Ashok Kumar Tiwari · Laxmi Chouhan
Frontiers in Genome Editing
doi 10.3389/fgeed.2025.1729535
Original Research
Published
Functional study of a novel SCN4A variant c.611C>T identified in a Japanese patient with myasthenia
Natsuki Kira · Kosuke Yoshida · Satoe Takahashi · Ayami Yamanaka · Takashi Kimura · Kazuaki Homma · Masanori P. Takahashi · Tomoya Kubota
Frontiers in Biophysics
doi 10.3389/frbis.2025.1710099
Review
Published
Targeting the JAK2V617F mutant hematopoietic microenvironment in myeloproliferative neoplasm
Amar Yeware
Frontiers in Hematology
doi 10.3389/frhem.2025.1694867
Review
Published
Targeting frustration: a review on reducing abnormal behaviors in broiler breeders via environmental enrichment
Marcela A. Quino · Bethany Baker-Cook
Frontiers in Ethology
doi 10.3389/fetho.2025.1717389
Review
Published
Aging and Alzheimer’s: the critical role of mitochondrial dysfunction and synaptic alterations
Pinky · Zitin Wali · Neha · Prachi Tiwari · Mohamed El-Tanani · Syed Arman Rabbani · Suhel Parvez
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2025.1676317
Mini Review
Published
High-performance electromagnetic calorimeter with oriented crystals to open new pathways in particle and astroparticle physics
L. Bandiera · P. Fedeli · the Oriented Calorimeter Collaboration
Frontiers in Sensors
doi 10.3389/fsens.2025.1659893
Original Research
Published
Characteristic brain function and network activity patterns in adolescent first-episode depression: a resting-state functional magnetic resonance imaging study
Liulu Zhang · Pingping Jie · Jie Zhao · Yuting Fu · Yong Liu · Bo Xiang · Jun Lv · Weidan Luo
Frontiers in Neuroimaging
doi 10.3389/fnimg.2025.1677410
Review
Published
Epigenetic dysregulation in pancreatic cancer: emerging biomarkers and clinical applications
Hina Sultana · Abhishikt David Solomon · Atif Khurshid Wani · Surendra K. Shukla
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1723159
Original Research
Published
Evidence of spatial periodic firing in the subiculum of mice
P. Abad-Perez · G. Rigamonti · F. J. Molina-Paya · G. Cabral-Pereira · Miriam Esteve-Campello · R. Scott · V. Borrell · L. Martínez-Otero · A. Falco · J. R. Brotons-Mas
Frontiers in Neural Circuits
doi 10.3389/fncir.2025.1648844
Epigenetics and Epigenomics
Published
Epigenetic repurposing of carbohydrate metabolic inhibitors for insulin resistance: targeting DNMT1 and HDAC3 for β-cell restoration
Muhammad Javid Iqbal · Luis A. Salazar
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2025.1691949
Sensors
Published
ASIX: Single-photon, energy resolved X-ray imaging with 50 μ m hexagonal hybrid pixel
Massimo Minuti · Luca Baldini · Roberto Beccherle · Ronaldo Bellazzini · Ashish Bisht · Maurizio Boscardin · Alessandro Brez · Paolo Bruschi · Marco Ceccanti · Matteo Centis Vignali · Luca Frontini · Luigi Gaioni · Omar Hammad Ali · Luca Latronico · Valentino Liberali · Guido Magazzù · Alberto Manfreda · Massimo Manghisoni · Fabio Morsani · Leonardo Orsini · Luca Palini · Melissa Pesce Rollins · Michele Pinchera · Massimo Piotto · Alessandro Profeti · Paolo Prosperi · Lodovico Ratti · Andrea Ria · Sabina Ronchin · Carmelo Sgrò · Stefano Silvestri · Gloria Spandre · Alberto Stabile · Gianluca Traversi · Gabriella Trucco · Monica Vasquez · Danny Zanardo
Frontiers in Sensors
doi 10.3389/fsens.2025.1599365
Musculoskeletal Disorders
Published
Association of National Area Deprivation Index with dietary patterns and pain-related inflammatory biomarkers in community-dwelling adults with chronic low back pain
Larissa J. Strath · Jonas G. Dembowski · Javier A. Tamargo · Andrew M. Sims · Demario S. Overstreet · Terence M. Penn · Rahm J. Bakshi · Eeshaan Bajaj · Tammie L. Quinn · D. Leann Long · Robert E. Sorge · Burel R. Goodin
Frontiers in Musculoskeletal Disorders
doi 10.3389/fmscd.2025.1601314
Molecular Medicine
Published
Antibody-drug conjugates targeting the cadherin, claudin and nectin families of adhesion molecules
Masuko Katoh · Yohann Loriot · Izuma Nakayama · Akinobu Hamada · Kohei Shitara · Masaru Katoh
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2025.1661016
Bee Science
Published
The effect of neonicotinoids on bumblebees (Bombus spp.): a systematic review
Daisy J. Dennis · Alexandra J. Gibbs
Frontiers in Bee Science
doi 10.3389/frbee.2025.1657493
Synthetic Biology
Published
pTARGEX vectors: a versatile toolbox for plant-based protein expression
Camille Chartrand-Pleau · Emily Gallipeau-Burns · Ananya Jain · Victor Boddy · Patrick Fakhouri · Sarah Rehmani · Teagan Thomas · Michelle Drapeau · Jordan T. VanderBurgt · Arnaud Boudigou · Adam M. Damry · Allyson M. MacLean
Frontiers in Synthetic Biology
doi 10.3389/fsybi.2025.1619871
Drug Delivery
Published
Strategies for delivering drugs across the blood-brain barrier for the treatment of neurodegenerative diseases
Xiaopei Zhang · Manfei Fu · Yuanfei Wang · Tong Wu
Frontiers in Drug Delivery
doi 10.3389/fddev.2025.1644633