ReviewPublished 30 September 2026Mitochondrial dysfunction and PANoptosis-related signaling in acute central nervous system injuries: mechanistic convergence and therapeutic opportunitiesHongbo Zhang · Ruoxin Tu · Dawei Zhang · Hao Tian · Hongna YinFrontiers in Molecular Neurosciencedoi 10.3389/fnmol.2026.1982074
Original ResearchPublished 30 September 2026Between science, religion, and tradition: multiple forms of legitimation of occult practices in contemporary KazakhstanEssenzhol Aliyarov · Marhabbat Nurov · Dinara Zhanguzhekova · Dauren Nessipkaliyev · Tussubzhan DuzbayevFrontiers in Political Sciencedoi 10.3389/fpos.2026.1895091
MethodsPublished 30 September 2026Protocol for non-viral HDR-based CRISPR/Cas9 platform for small custom editing in primary T cellsKatariina Mamia · Anniken Solveig Matheson Sollano · Vanja Lundberg · Svetlana Vakkilainen · Eliisa Kekäläinen · Camilla Schalin-Jäntti · Eira Leinonen · Børre Fevang · Juha Grönholm · Timi Martelius · Shiva Dahal-Koirala · Emma Maria HaapaniemiFrontiers in Genome Editingdoi 10.3389/fgeed.2026.1817322
ReviewPublished 30 September 2026Gene therapy for non-obstructive azoospermia: therapeutic avenues and translational pathway to clinical applicationMan-Xi Jiang · Tao Jing · Huai L. Feng · Yan ZhuFrontiers in Genome Editingdoi 10.3389/fgeed.2026.1921175
PerspectivePublished 30 September 2026Glycan-intrinsic monoclonal antibody biomanufacturingAron GyorgypalFrontiers in Chemical Engineeringdoi 10.3389/fceng.2026.1955792
ReviewPublished 30 September 2026MSC-derived extracellular vesicles for spinal cord injury: inflammatory microenvironment modulation, stage-dependent repair mechanisms, and translational challengesHang Yu · Yifan Liu · Shulong Yin · Haoyue Hu · Linquan Li · Taotao Zhu · Jie Liu · Sheng Liu · Chenxi Zhao · Shiqing FengFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.1960271
ReviewPublished 30 September 2026Gut microbiota–cancer crosstalk: emerging molecular targets for personalized cancer treatment- a comprehensive reviewPooja Negi · Arpita Upreti · Preeti Budhlakoti · Amit Kumar Sen · Mitali Danu · Sumit Tewari · Nirmal Joshi · Deepak Chandra JoshiFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1924197
ReviewPublished 30 September 2026Emerging NPR-B agonists for cartilage and bone: from CNP biology to translational compound designYasuhiko Ago · Amali Karunathilaka · Jacky M. Guerrero-Vargas · Shunji TomatsuFrontiers in Chemistrydoi 10.3389/fchem.2026.1949456
PerspectivePublished 30 September 2026Neuroimmune phenotypes in brain aneurysms and neurodegenerative diseasesFrancis J. Lauzier · David C. LauzierFrontiers in Neurosciencedoi 10.3389/fnins.2026.1916561
Conceptual AnalysisPublished 29 September 2026From eco-affective narrowing to agency: acceptance, externalization, and efficacy in climate-related cognitionPaolo RaileFrontiers in Cognitiondoi 10.3389/fcogn.2026.1927324
OpinionPublished 29 September 2026Beyond pulmonary arterial hypertension: sotatercept across the advanced heart failure and transplant continuumAndrew Xanthopoulos · Christos Kourek · Dimitrios E. Magouliotis · Filippos Triposkiadis · Alexandros BriasoulisFrontiers in Transplantationdoi 10.3389/frtra.2026.1966659
Original ResearchPublished 29 September 2026Virtual reality-assisted psychological treatment of aggression for violent offenders: a pilot descriptive case series in maximum-security forensic psychiatryFernando Renee González Moraga · Sean Perrin · Pia Enebrink · Kristina Sygel · Wim Veling · Märta WalliniusFrontiers in Health Servicesdoi 10.3389/frhs.2026.1920018
MethodsPublished 29 September 2026MuscleSCS: a standardized programming framework combining neural neuromodulation and spinally mediated paraspinal muscle modulationMatthias Hubert MorgallaFrontiers in Pain Researchdoi 10.3389/fpain.2026.1954865
ReviewPublished 29 September 2026New insight into Alzheimer’s disease: small molecule-Aβ in the brain transport and peripheral organ clearanceTianci Ma · Yongyi Li · Yuting Ding · Shijie Liu · Chuanhao Gao · Xiang Li · Zhiqian Tong · Yan LvFrontiers in Agingdoi 10.3389/fragi.2026.1921485
EditorialPublished 29 September 2026Editorial: Metabolomic analysis of plant matrices: identification of compounds of therapeutic and nutraceutical interestMariacaterina Lianza · Victor Aguilar-HernándezFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1996217
Systematic ReviewPublished 29 September 2026Comparison of group and individual therapy in physiotherapy, occupational therapy, and speech therapy: a systematic reviewMichael Minor · Elisabeth Plath · Carsten Volland · Silke Neusser · Anna BußmannFrontiers in Rehabilitation Sciencesdoi 10.3389/fresc.2026.1904321
CorrectionPublished 29 September 2026Correction: Pathological similarities between degenerative enthesopathy and rheumatic enthesitis: the role of ECM stiffness and Wolff's Law-based mechanical stimulation as a therapeutic strategyKang Ahn · Aerisa Ahn · Seung Jun Oh · Hyun Sung KimFrontiers in Rehabilitation Sciencesdoi 10.3389/fresc.2026.1999671
Original ResearchPublished 29 September 2026Multimodal rehabilitation for hard flaccid syndrome in a retrospective case seriesChristopher L. Mendias · Tariq M. AwanFrontiers in Rehabilitation Sciencesdoi 10.3389/fresc.2026.1970062
Original ResearchPublished 29 September 2026Human β defensin type 2 based novel antimicrobial peptide prediction using both molecular dynamics simulation and artificial intelligence methodsIshrat Jahan · Hailemicael Lulseged Yimer · Kushal Badal · Michaela Brady · Jason J. Guo · Bryce Richardson · Letu Qingge · Liqun ZhangFrontiers in Chemistrydoi 10.3389/fchem.2026.1913090
ReviewPublished 29 September 2026Neurobiological mechanisms and brain network dysfunction in major depressive disorder: an integrative reviewDina Iskakova · Burcu Yener · Altyngul Kamzanova · Aygul Sitakanova · Rifat Hamoudi · Almira KustubayevaFrontiers in Integrative Neurosciencedoi 10.3389/fnint.2026.1904444
PerspectivePublished 29 September 2026Towards a nonlinear “neuroimmune gate-model”: beyond stellate ganglion block and vagus nerve stimulationLorenz Fischer · Hans-Georg SchaibleFrontiers in Neurosciencedoi 10.3389/fnins.2026.1976225
ReviewPublished 28 September 2026Decoding host–microbiome interactions through integrative multi-omics and artificial intelligence: from biological mechanisms to predictive modellingGayatri Krishna S. · Narchikundil Reeja · Shemmy Sadanandan · Bhagya Mappurath · Akash Chatterjee · Ginny Antony · Tony GraceFrontiers in Microbiomesdoi 10.3389/frmbi.2026.1906484
ReviewPublished 28 September 2026Advances in electroactive materials-based strategies for promoting skin wound healingHaihong Ge · Xi Ren · Zeyuan LeiFrontiers in Medical Technologydoi 10.3389/fmedt.2026.1919503
ReviewPublished 28 September 2026Bio-based nanophotothermal systems as smart drug delivery platforms for multimodal synergistic cancer therapy—a reviewAleksandra Porjazoska KujundziskiFrontiers in Medical Technologydoi 10.3389/fmedt.2026.1943029
Systematic ReviewPublished 28 September 2026Immersive simulation interventions for children and adolescents with autism spectrum disorder: technologies, cognitive and socio-emotional development, and AI-driven emotion estimation: a systematic reviewMohammad Mominur Rahman · Khansa Chemnad · Marwa Al Assi · Areej Babiker · Achraf OthmanFrontiers in Virtual Realitydoi 10.3389/frvir.2026.1850096
ReviewPublished 28 September 2026High-order chromatin structures mediated by phase separation in cell senescenceWenjing Sun · Boxian Li · Zhaoyong Xu · Jing Wang · Jing Cao · Yangzhong Wang · Jiale Wang · Wenbo Gu · Pengjun Xu · Liang Wang · Wenyan XieFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1896884
ReviewPublished 28 September 2026Next-generation polymeric nanoparticles for regenerative endodontics: engineering the pulp microenvironment beyond antimicrobial therapyRosana Farjaminejad · Neeki Jabbari · Alexander Garcia-Godoy · Franklin Garcia-Godoy · Elnaz TavazozadehFrontiers in Dental Medicinedoi 10.3389/fdmed.2026.1972546
ReviewPublished 28 September 2026Phytocannabinoid-drug interactions: pharmacokinetic and pharmacodynamic mechanisms, clinical relevance and toxicological considerationsDiogo Alexandre Gomes · Wellyngton Vieira Eufrázio · Marcella Silva Ribeiro · Linério Ribeiro de Novais Júnior · Flávia Rigo · Patrícia de Aguiar Amaral · Antonella Campanale · Antônio Inserra · Rafael Mariano de BitencourtFrontiers in Toxicologydoi 10.3389/ftox.2026.1952599
ReviewPublished 28 September 2026Chromatin remodeling in bone organoids: from epigenetic regulation to disease modeling and therapeutic translationYuxin Zheng · Desheng Liu · Jun Hou · Hong Ding · Yingying HeFrontiers in Geneticsdoi 10.3389/fgene.2026.1975296
ReviewPublished 28 September 2026Multipath interaction network of annexin A2: multifaceted regulation and translational perspectives in neurological diseasesYong Guan · Ping Gu · Dachuang Guo · Liqiang Huang · Dongye Lian · Caicai Zhang · Jigao Feng · Hao PengFrontiers in Geneticsdoi 10.3389/fgene.2026.1916220
ReviewPublished 28 September 2026Mitochondrial metabolic plasticity in cancer: hybrid bioenergetic states and translational targeting in surgical oncologyDebdeep Chattopadhyay · Ramya Lakshmi Rajendran · Nida Mubin · Durva Tendulkar · Thoudam Debraj Singh · Subhrojyoti Ghosh · Saurabh Kumar Jha · Prakash Gangadaran · Byeong-Cheol AhnExperimental Biology and Medicinedoi 10.3389/ebm.2026.11244
Brief Research ReportPublished 25 September 2026Identification of antibiotic resistance genes in fecal microbiota selected donors during the establishment of a biobank in the south of BrazilLucas de Figueiredo Soveral · Liandra Raphaella de Lima Holanda · Izadora Borgmann Frizzo Assunção · Leticia Gonçalves Gomes · Isabella Bittencourt de Souza · Gabriella de Souza Rodrigues · Patrícia Almeida Vanny · Oscar Bruna-Romero · Jussara Kasuko Palmeiro · Mara Cristina Scheffer · Thais Cristine Marques Sincero · Carlos Rodrigo Zárate-BladésFrontiers in Antibioticsdoi 10.3389/frabi.2026.1905540
Original ResearchPublished 25 September 2026Virtual screening of phytochemicals against multiple protein targets of Alzheimer’s diseaseSamuel Mesfin · Naamah Bloch · Abraham O. SamsonFrontiers in Drug Discoverydoi 10.3389/fddsv.2026.1922953
ReviewPublished 25 September 2026CLDN18 and FGFR2 splicing variants are emerging tumor-associated antigens for cancer therapyMasuko Katoh · Masaru KatohFrontiers in Molecular Medicinedoi 10.3389/fmmed.2026.1927389
ReviewPublished 25 September 2026Targeting gut dysbiosis: a new frontier in MASLD managementShweta Sharma · Arun Pachauri · Harshal Nagar · Vishwa Thakkar · Kajal PatelFrontiers in Systems Biologydoi 10.3389/fsysb.2026.1937809
ReviewPublished 25 September 2026Post-stroke spasticity: advances in network mechanisms and therapeuticsWei Yao · Yuanbin Yang · Zhiyi Wang · Longyue Yi · Deya Daneva · Zhuangwei Fang · Keyun Gan · Zhiqi LinFrontiers in Human Neurosciencedoi 10.3389/fnhum.2026.1868901
Original ResearchPublished 25 September 2026Integrated computational investigation of Glycosmis pentaphylla -derived compounds against major venom proteins of Daboia russeliiSana S. Hussain · Danie J. KingsleyFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1906533
ReviewPublished 25 September 2026Decellularized dental pulp extracellular matrix for pulp-dentin regeneration: a narrative review of processing, bioactivity, delivery, preclinical evidence, and translational challengesXinli Zhang · Mengjie DongFrontiers in Dental Medicinedoi 10.3389/fdmed.2026.1962311
ReviewPublished 25 September 2026Epigenetic, chromatin-associated, and epitranscriptomic regulation in chronic pain: mechanisms and translational prospectsJianan You · Lei LiFrontiers in Geneticsdoi 10.3389/fgene.2026.1904744
ReviewPublished 24 September 2026Black boxes and petri dishes: AI models for antimicrobial pharmacokinetics, drug properties, and resistanceJacob K. McPherson · Surbhi Sharma · Biswajit Mishra · Fadi Shehadeh · Eleftherios MylonakisFrontiers in Bacteriologydoi 10.3389/fbrio.2026.1926678
Case ReportPublished 24 September 2026Metabolic and neuropathic outcomes following combined sodium-glucose cotransporter-2 inhibitor therapy and adjunctive acupuncture in obese patients with diabetic neuropathy: a case seriesYun Jin KimFrontiers in Pain Researchdoi 10.3389/fpain.2026.1886313
ReviewPublished 24 September 2026Hyperbaric oxygen therapy in sepsis-associated encephalopathy: pathophysiological rationale, preclinical evidence, and translational challengesYikun Xie · Yihao Li · Yujing Li · Shuai Chen · Guanqi Song · Hongyu WangFrontiers in Cellular Neurosciencedoi 10.3389/fncel.2026.1941147
ReviewPublished 24 September 2026AI-driven multi-omics integration in breast cancer: clinical applications, immunotherapy prediction, and translational challengesZi-Yao Wang · Na Liu · Min-Bin ChenFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1875788
Original ResearchPublished 24 September 2026Integrative multi-omics characterization of KLRB1/CD161 in diffuse large B-cell lymphoma: associations with immune context, subtype biology, and therapeutic responseErwei Li · Yingying Tang · Yuanyuan Wanyan · Yu LiangFrontiers in Molecular Biosciencesdoi 10.3389/fmolb.2026.1903725
Original ResearchPublished 24 September 2026Novel chitosan-encapsulated ZnO NPs@Subtilisin: enzyme immobilized as next-generation nanoplatform for antimicrobial and anticancer controlRua J. Kadhim · Majid S. Jabir · Ghassan M. Sulaiman · Uday M. Nayef · Suresh GhotekarFrontiers in Materialsdoi 10.3389/fmats.2026.1922253
Mini ReviewPublished 24 September 2026Time-resolved phenotyping of seizure evolution in developmental and epileptic encephalopathy: insights and gaps from the CYFIP2 Arg87Cys mouse modelRuiying Ma · U Suk Kim · Yousun Chung · Kihoon HanFrontiers in Synaptic Neurosciencedoi 10.3389/fnsyn.2026.1963161
ReviewPublished 23 September 2026Immunosuppressive cell populations as potential drivers of extrinsic immune checkpoint inhibition resistance in clear cell renal cell carcinomaUsman Humayun TemuriOncology Reviewsdoi 10.3389/or.2026.1953850
Original ResearchPublished 23 September 2026Effect of silymarin on Helicobacter pylori growth and adhesion: in vitro and in silico evaluationVitor Zorzal Majeski · Milena Lopes Francisco Bittencourt · Pedro Henrique Tregnago · Dalila Nickel Loose · Leonardo Bruno Federico · Rodrigo Rezende Kitagawa · Rita de Cássia Ribeiro GonçalvesFrontiers in Natural Productsdoi 10.3389/fntpr.2026.1890760