Review
Published
Beyond static biomarkers: systems biology and AI for decoding cancer dynamics
Subhajit Dutta · Anjana Goli
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1855016
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Articles
Every article on Frontiers is peer reviewed, permanently archived and free to read.
Showing 417 articles
Original Research
Published
Genetic evidence for causal relationships between brain functional networks and domain-specific recovery after nondisabling ischemic stroke
Huan Cai · Zhenchun Huang · Jialin Liang · Hao Zhang · Zhonghua Liu
Experimental Biology and Medicine
doi 10.3389/ebm.2026.10948
Mini Review
Published
Intrinsically disordered regions as drivers of protein aggregation: mechanisms, phase separation, and emerging predictive frameworks
Rahul Kaushik · Suyong Re
Frontiers in Biophysics
doi 10.3389/frbis.2026.1880887
Original Research
Published
Mechanistic evaluation of water removal dynamics in stabilised human urine for circular fertiliser production
Charles B. Niwagaba · Anastasija Vasiljev · Mathias Kasirye · Andrew Lubuulwa · Alex Y. Katukiza · Swaib Semiyaga · Musa Manga · Prithvi Simha
Frontiers in Chemical Engineering
doi 10.3389/fceng.2026.1892312
Hypothesis and Theory
Published
Neuroinflammation as a failure of allostatic integrity: a hierarchical-circular model of biological memory for pathogenesis in neurodegenerative and neuropsychiatric diseases
Samuel Ruesga Mundo
Frontiers in Systems Neuroscience
doi 10.3389/fnsys.2026.1888548
Original Research
Published
Virtual screening and mechanistic elucidation of myricetin as a quorum sensing inhibitor targeting AhyI in Aeromonas hydrophila
Bingxin Li · Qiyu Gu · Boqiang Wei · Hui Geng · Li Xiong
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1815299
Perspective
Published
The Remission Therapy Inquiry-Based Research Model (RIRM): a conceptual framework for mechanistic hypothesis generation
Pichit Suvanprakorn · Krit Pongpirul
Frontiers in Systems Biology
doi 10.3389/fsysb.2026.1835804
Review
Published
Small particles, big environmental impact: the sustainable chemistry of iron sulfide nanomaterials
Manjinder Kour · Sapana Jadoun · Raakhi Gupta
Frontiers in Environmental Chemistry
doi 10.3389/fenvc.2026.1829659
Hypothesis and Theory
Published
Time as event: bridging explicit and emergent temporal representations in computer-based social simulations
Juan A. Barceló · Joaquim Fort · Albert García Piquer · Olga Palacios · Ramón Buxó · Jaume Noguera
Frontiers in Complex Systems
doi 10.3389/fcpxs.2026.1838587
Hypothesis and Theory
Published
Δ 9 -tetrahydrocannabinol, a cannabis sativa–derived natural product, as a probe of endocannabinoid system plasticity in type 1 diabetes: a receptor-level, testable hypothesis
Wojciech Łukowski
Frontiers in Natural Products
doi 10.3389/fntpr.2026.1812441
Review
Published
Physical feasibility gating in early drug discovery: a decision framework for identifying predictable physical failures, with retrospective illustration
Sarfaraz K. Niazi
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1799663
Original Research
Published
Selective adsorption of Pb 2+ from acid mine drainage through a poly (hydroxamic acid) (PHA) ligand: an HSAB-guided coordination mechanism
Nozipho Nompumelelo Mzinyane
Frontiers in Environmental Chemistry
doi 10.3389/fenvc.2026.1835320
Hypothesis and Theory
Published
Persistent Afferent Bias: a mechanistic link between somatic disruption and autonomic dysregulation
Boris Živný
Frontiers in Integrative Neuroscience
doi 10.3389/fnint.2026.1848233
Systematic Review
Published
Site selection for aquaculture of extractive species in open ocean environments: a systematic review with focus on ecological carrying capacity
Apsara Liyanwala · Sabine Horn · Bela H. Buck
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1852458
Review
Published
Inducible two-step cultivation of microalgae: engineering the growth and lipid biosynthesis for biofuel production
Krishnakumar Mohan · Arathi Sreenikethanam · Subhisha Raj · Niharika Mondru · Amit K. Bajhaiya
Frontiers in Fuels
doi 10.3389/ffuel.2026.1860328
Mini Review
Published
Phenotypic plasticity in fish cell lines: conceptual links to aquatic epigenetics
Daisuke Ikeda
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1867376
Hypothesis and Theory
Published
Hierarchical-circular model of biological memory: a multilevel hypothesis for pathogenesis and allostatic integrity in Alzheimer’s disease and related dementias
Samuel Ruesga Mundo
Frontiers in Dementia
doi 10.3389/frdem.2026.1841647
Review
Published
Therapeutic priming of liver regeneration: from mechanisms to ex vivo machine perfusion
Sarah Yoshimi Tropp · Dinesh Jaishankar · Carl Atkinson · Satish N. Nadig
Frontiers in Transplantation
doi 10.3389/frtra.2026.1841091
Original Research
Published
Optimal lemongrass (Cymbopogon citratus) supplementation improves growth, feed efficiency, and digestive development without altering hematological status in red tilapia (Oreochromis spp.)
Robert Dela Cerna Comahig · Matthew Stephen Mejia Tundag · Junmer T. Serrano · Jodelo C. Rabuya · Jaynos R. Cortes
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1841385
Review
Published
Impact of plant-based interventions on gynecological cancers: a narrative review of mechanistic interplays and clinical evidence
Fidelis Batale Fabrael · John Sotunsa · Kehinde Samuel Olaniyi · Onome Bright Oghenetega · Oluwatobi Adewale · Blessing Monica Akindele · Faith Olanrewaju · Nekabari Lekpa Gbimadee · Seyi Olayemi · Abosede Oreoluwa Bolaji · Marvellous Osewe Iyobhebhe · Emmanuel Mololuwa Adegbotoluwa · Emmanuel Damilare Folahanmi · John Ahmadu Kaisar · Precious Adeoye Oyedokun
Frontiers in Molecular Medicine
doi 10.3389/fmmed.2026.1832188
Original Research
Published
Essential oil from Artemisia gmelinii extenuates cellular integrity of Sporothrix globosa and its biofilms by steering intracellular ROS and basal ergosterol levels
Acharya Balkrishna · Manisha Kabdwal · Monali Joshi · Yash Varshney · Meenu Tomer · Pardeep Nain · Savita Lochab · Anurag Varshney
Frontiers in Fungal Biology
doi 10.3389/ffunb.2026.1842749
Brief Research Report
Published
Mitochondrial morphology and mtDNA content in fibroblasts from patients with different types of mucopolysaccharidosis
Klaudia Walczak · Lidia Gaffke · Karolina Pierzynowska · Natalia Sowa-Rogozińska · Ewa Piotrowska
Acta Biochimica Polonica
doi 10.3389/abp.2026.16345
Original Research
Published
Combining machine learning and physiological network models for sepsis prediction
Juri Backes · Artyom Tsanda · Tobias Knopp · Wolfgang Renz · Eckehard Schöll
Frontiers in Network Physiology
doi 10.3389/fnetp.2026.1852577
Perspective
Published
Glyphosate: North America's toxic food crops and the enduring legacy of disease
J. A. Barnett · D. L. Gibson
Frontiers in Environmental Health
doi 10.3389/fenvh.2026.1863758
Review
Published
The safety case for a deep geological repository in Switzerland: site and geological barrier characteristics
Raphael A. J. Wüst · Michael Schnellmann · Angela Landgraf · Silvio Giger · Nicolas Roy · Daniel Traber · Gaudenz Deplazes · Raphael Schneeberger · Jens K. Becker · Nathan Looser · Urs H. Fischer · Valentina Zampetti · Tim Vietor
Frontiers in Nuclear Engineering
doi 10.3389/fnuen.2026.1849685
Review
Published
An evolutionary genomic perspective on preterm birth, genome editing, and pregnancy in the human species
Akua A. Obeng · Monica Uddin · Chengqi Wang · Derek E. Wildman
Frontiers in Genome Editing
doi 10.3389/fgeed.2026.1805932
Original Research
Published
Fleeing is believing: adaptive behavior under social threat as an inference process
Hridai S. Khurana · Valeria Mussetto · Leiron Ferrarese · Cornelius T. Gross · Rory J. Bufacchi
Frontiers in Neural Circuits
doi 10.3389/fncir.2026.1812938
Review
Published
Mechanistic insights into the synaptic damage-repair and regeneration processes in neurodegenerative Alzheimer’s disease: phytochemicals as neuroprotective agents
Bharti Yadav · Prabhakar Gangwar · Kirti Kumari · Anuradha Yadav · Rashmi Rao · Keshav Kumar · Harkomal Verma · Monisha Dhiman · Anil Kumar Mantha
Frontiers in Synaptic Neuroscience
doi 10.3389/fnsyn.2026.1835778
Perspective
Published
Emerging role of genipin as a therapeutic in diseases of the peripheral nervous system
Archie Patel · Nadja Zeltner
Frontiers in Biomaterials Science
doi 10.3389/fbiom.2026.1852025
Review
Published
Role of angiotensin-converting enzyme in cognitive aging: evidence from preclinical and clinical studies
Joshua Smith · Prakashkumar Dobariya · Tanvi R. Kadam · Swati S. More
Frontiers in Drug Discovery
doi 10.3389/fddsv.2026.1855021
Original Research
Published
Associative emotional memory encoding: insights from network stability analysis of an fMRI-driven bilinear dynamics
Weronika Dziarnowska · Melis Orhun · Yannan Zhu · Nils Kohn · Guillén Fernández · Matin Jafarian
Frontiers in Systems Neuroscience
doi 10.3389/fnsys.2026.1794170
Original Research
Published
Comparative metabolomics provides insights into the metabolic reprogramming of the predatory Arma custos (Fabricius) during low-temperature storage
Yifan Dong · Xiaoyan Yuan · Zihan Shi · Yansong Xiao · Shaolong Wu · Can Wang · Lin Tan · Weiai Zeng · Yusheng Wang
Frontiers in Insect Science
doi 10.3389/finsc.2026.1820584
Review
Published
Integrative perspectives on electroacupuncture modulation of vagal–cholinergic and neuro–immune–metabolic regulation in long COVID
Liwen Wang · Xiaoyang Hu · Dongning Yan
Frontiers in Integrative Neuroscience
doi 10.3389/fnint.2026.1775007
Review
Published
Vector-amplified toxicity of microplastics and heavy metals in aquatic invertebrates: mechanistic insights and implications for sustainable aquaculture
Jaynos R. Cortes · John Lloyd F. Penionez · Jay D. Tering · Fabio C. Ruaza
Frontiers in Aquaculture
doi 10.3389/faquc.2026.1841755
Review
Published
Glycan-encoded immune checkpoints and allorecognition: a mechanistic framework for transplantation and organ engineering
Md Mohosin Rana · Stephen G. Withers · Jonathan C. Choy · Jayachandran N. Kizhakkedathu
Frontiers in Transplantation
doi 10.3389/frtra.2026.1841203
Study Protocol
Published
Assessing sleep, cognition and overnight memory performance in neurotypically developing youth in a children's hospital
Gabrielle N. Deutsch · Emmet W. Klein · Chelsea E. Cadle · Katharine C. Simon · H. Gerry Taylor · Maninder Kalra · Paola Malerba
Frontiers in Sleep
doi 10.3389/frsle.2026.1771860
Original Research
Published
Exploring the spiking neural autoencoder: from hyperexcitability to noise-driven compensation
Mohammadreza Khodashenas · Daniel P. Martins
Frontiers in Systems Neuroscience
doi 10.3389/fnsys.2026.1788937
Review
Published
Pruritogenic mediators in atopic dermatitis: mechanisms of neurogenic crosstalk
Lai-San Wong · Jen-Hau Yang · Yu-Ta Yen · Jenq-Lin Yang
Journal of Cutaneous Immunology and Allergy
doi 10.3389/jcia.2026.16460
Original Research
Published
Decoding basal ganglia motor circuit dysfunction from handwriting: a physics-informed neural signal interpretation framework for Parkinson's disease screening
Krishnan Batri · S. Lakshmi · Salabat Khan · Zeshan Iqbal · Mohammad Alhefdi · Ghada Atteia · Sivaram Murugan
Frontiers in Neuroinformatics
doi 10.3389/fninf.2026.1814920
Review
Published
Revisiting the clastosome: a stress-induced nuclear proteolytic compartment of mammalian cells
Miguel Lafarga · María T. Berciano · Noemí Rueda · Sofía Cardona-Cortés · Olga Tapia
Frontiers in Neuroanatomy
doi 10.3389/fnana.2026.1839944
Perspective
Published
The fourth controlled release society workshop on oral peptide administration
David J. Brayden · Stephen T. Buckley · Andrew L. Lewis
Frontiers in Drug Delivery
doi 10.3389/fddev.2026.1860678
Original Research
Published
Effects of climate change on a nocturnal gecko: an integrative analysis
Ticiane de Lima Costa · Arinos de Oliveira Serpa · Arthur Sena · Bruno Araújo de Souza · Gabriel Henrique de Oliveira Caetano · Heitor Campos de Sousa · Júlio Miguel Alvarenga da Silva · Leandro Braga Godinho · Luisa Maria Diele-Viegas · Naiane Arantes Silva · Vitor Hugo Cavalcante · Guarino Rinaldi Colli
Frontiers in Amphibian and Reptile Science
doi 10.3389/famrs.2026.1753497
Original Research
Published
Circuit dynamics of binocular conflict in mouse primary visual cortex
Daniel P. Montgomery · Daniel A. Bowen · Jin Wu · Mark F. Bear · Eric D. Gaier
Frontiers in Systems Neuroscience
doi 10.3389/fnsys.2026.1786396
Systematic Review
Published
Environmental epigenetic modifiers in neurodegenerative diseases: a systematic review of epigenomic mechanisms and therapeutic targets
Pranay Wal · Sunita Mishra · Debashish Pradhan · Ankita Wal · Debashis Purohit · Lalit Mohan Nainwal · Vivek Dhir · Amin Gasmi
Frontiers in Epigenetics and Epigenomics
doi 10.3389/freae.2026.1833533
Review
Published
Research overview—2025: integrating scientific progress to accelerate global tuberculosis elimination
Patrick K. Moonan · Timothy H. Holtz
Frontiers in Tuberculosis
doi 10.3389/ftubr.2026.1805962
Review
Published
Microbial interventions in rice rhizosphere engineering: from soil microbiome manipulation to yield stability
Qudrat Ullah · Waqas Haider · Muhammad Usama
Frontiers in Industrial Microbiology
doi 10.3389/finmi.2026.1832866
Original Research
Published
Tolazoline, an alpha-adrenergic antagonist, may also block xylazine at off-target sites as inferred from molecular docking
Giuseppe Floresta · Vincenzo Patamia · Alberto Granzotto · Davide Arillotta · Gabriele Duccio Papanti · Amira Guirguis · John M. Corkery · Giovanni Martinotti · Stefano L. Sensi · Fabrizio Schifano
Frontiers in Chemical Biology
doi 10.3389/fchbi.2026.1806456
Perspective
Published
Plant agency: from senome and electrome to plant semiosphere
Luís Felipe Basso · Frantisek Baluška · Gustavo Maia Souza
Frontiers in Plant Physiology
doi 10.3389/fphgy.2026.1861112