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New imaging method maps memory circuits at single-cell resolution

A light-sheet technique lets neuroscientists follow how memories are stored across thousands of neurons at once.

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Researcher reviewing brain imaging on a monitor in a laboratory

A team of neuroscientists has developed an imaging approach that records the activity of thousands of individual neurons while a memory forms.

A clearer view of the brain

The method combines light-sheet microscopy with a new fluorescent marker, reducing tissue damage and extending recording time.

The authors have released their analysis pipeline openly so other laboratories can reproduce the results.

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