Advanced Biosensors and Bioelectronic Platforms for Precision Healthcare

Recent advances in biosensors and bioelectronic platforms are reshaping precision healthcare by enabling rapid, sensitive, and minimally invasive detection of clinically relevant biomarkers. The integration of functional nanomaterials, electrochemical transduction, wearable and implantable devices, and microfluidic lab-on-a-chip systems has greatly expanded the capabilities of next-generation healthcare technologies for early diagnosis, continuous monitoring, and decentralized testing. In parallel, emerging data-driven approaches are improving biosensor signal interpretation, supporting more accurate and actionable clinical decision-making.Despite these advances, major challenges remain in translating biosensing technologies from proof-of-concept studies to practical healthcare applications. Key barriers include device miniaturization, long-term operational stability, sample-to-answer integration, multiplexed detection, manufacturing scalability, and validation in clinically relevant settings. There is therefore a strong need for interdisciplinary efforts that combine materials science, engineering, biology, and medicine to develop robust biosensors and bioelectronic systems tailored to real healthcare needs.This Research Topic aims to bring together cutting-edge studies on the design, fabrication, integration, and application of advanced biosensors and bioelectronic platforms for healthcare. By highlighting innovations in sensing interfaces, device architectures, analytical performance, and translational implementation, this collection seeks to accelerate the development of practical biosensing solutions for personalized diagnosis, disease monitoring, and improved health outcomes.This Research Topic welcomes original research, reviews, mini reviews, perspectives, and methods articles focused on biosensors and bioelectronic platforms for healthcare applications. Submissions should advance the development, integration, or clinical translation of biosensing systems that enable sensitive, specific, and accessible healthcare diagnostics and monitoring.Topics of interest include, but are not limited to:o Electrochemical, impedance-based, and other bioelectronic biosensing platforms for healthcareo Wearable and implantable biosensors for continuous or real-time monitoringo Microfluidic-integrated biosensors and lab-on-a-chip systemso Point-of-care diagnostic platforms and decentralized testing deviceso Nanomaterial-enabled transducers and functional sensing interfaceso Immunosensors, aptasensors, and other advanced biorecognition strategieso Biochip design and multiplexed biomarker detectiono Biosensors for cancer, infectious diseases, metabolic disorders, neurological disorders, and other human diseaseso Sensor platforms for physiological monitoring and personalized healthcareo AI-assisted biosensor signal processing, pattern recognition, chemometrics, and data interpretationo Device miniaturization, integration, long-term stability, and cost-effective fabricationo Clinical validation, usability, manufacturability, and translational challenges of healthcare biosensorso Multi-sensor arrays, electronic tongues, and electronic noses.Studies are particularly encouraged when they demonstrate clear relevance to healthcare use cases, including early diagnosis, treatment monitoring, disease stratification, and remote or continuous patient monitoring. Topic editors: Biswajit Saha, Hadar Ben-Yoav, Pushpesh Ranjan Source: https://www.frontiersin.org/research-topics/79193/advanced-biosensors-and-bioelectronic-platforms-for-precision-healthcare