Advances in Diabetes and Hypertension Research - Volume II

Globally, diabetes represents a considerable burden on healthcare systems, with an age-standardized total prevalence of 6.1% in 2021. The burden of diabetes is predicted to increase further due to rising incidences of type 1 and type 2 diabetes, population aging, and the growing prevalence of comorbidities. This trend is expected to result in a further rise in hospitalizations among individuals with diabetes, significantly impacting patients’ quality of life, health status, and outcomes.Hypertension affects one in three adults worldwide. The number of individuals affected by hypertension doubled between 1990 and 2019, rising from 650 million to 1.3 billion. This common and deadly condition can lead to stroke, heart attack, heart failure, kidney damage, and other diseases. Alarmingly, only 21% of people with hypertension have their condition under control.Global evidence suggests that patients with both diabetes and hypertension are at a higher risk of cardiovascular disease due to several shared pathophysiological pathways. While various mechanisms have been proposed, the underlying relationship between these conditions, as well as the effects of novel therapeutic approaches, remain insufficiently explored. This highlights the need for further research.This Research Topic aims to provide insights into the complex connections between diabetes and hypertension, presenting recent developments in management strategies, clinical outcomes, antihypertensive treatment, and the pathological mechanisms underlying these relationships.Authors are invited to submit papers presenting innovative findings on the mechanisms underlying the relationship between diabetes and hypertension. While articles should cover a range of subjects, they are not limited to the following:- Pathophysiological mechanisms linking diabetes and hypertension- Cardiovascular complications and outcomes in patients with type 1 and type 2 diabetes and hypertension- Renal and cardiorenal interactions in diabetes-associated hypertension- Role of metabolic dysfunction, including insulin resistance and glycemic control, in blood pressure regulation- Determinants and outcomes of antihypertensive therapy in patients with type 1 and type 2 diabetes- Blood pressure control, targets, and variability in diabetic populations- Microvascular and macrovascular complications arising from the coexistence of diabetes and hypertension- Real-world evidence and population-based studies on the management of diabetes and hypertension Topic editors: Christiano Argano, Rosario Scaglione Source: https://www.frontiersin.org/research-topics/78018/advances-in-diabetes-and-hypertension-research---volume-ii