Advances in the Prevention and Management of In-Hospital Cardiac Arrest

In-hospital cardiac arrest (IHCA) is a global health issue affecting approximately 1 to 10 patients per 1000 admissions worldwide and causes immense morbidity and mortality. Despite significant advances in resuscitation care, only a small fraction of those who suffer IHCA survive to hospital discharge. Hospital systems around the world rely on international evidence-based treatment recommendations to guide IHCA management, yet many of these recommendations are based on limited or low-quality evidence, leaving critical knowledge gaps in IHCA care. Moreover, the rare recommendations stemming from high-quality evidence are most often derived from randomized clinical trials limited to out-of-hospital cardiac arrest (OHCA). Given the fundamental differences between IHCA and OHCA—including patient comorbidities, arrest etiologies, time to basic and advanced life support, and expected outcomes—recommendations extrapolated from OHCA data may not adequately address the unique challenges of IHCA care. These distinctions underscore the critical need for focused, IHCA-specific research to inform evidence-based clinical practice. This Research Topic seeks to advance the field of resuscitation science by highlighting emerging and innovative work focused on IHCA. We aim to provide a platform for a broad range of scientific literature that spans the full continuum of resuscitation, including arrest prevention, intra-arrest management, post-arrest care, education and systems of care. We welcome submissions of scholarly articles of all types that describe the epidemiology, risk stratification, or pathophysiology of IHCA; evaluate the efficacy or safety of IHCA-targeted interventions; or address methodological or implementation challenges to IHCA research, education or clinical practice. Themes of interest include, but are not limited to: 1) Arrest Prevention• Rapid Response Systems / Early Warning Scores• Machine-learning predictive algorithms / Health record–integrated alert systems• Pre-/Peri-arrest management2) Intra-Arrest Management• Age- or physiologic-based cutoffs for use of different resuscitation protocols (neonatal versus pediatric or pediatric versus adult)• Components of high-quality CPR: CPR quality targets (rate, depth, fraction)• Alterations and adaptations to conventional chest compressions (e.g., active compression-decompression, impedance threshold device, interposed abdominal compressions, prone CPR)• Airway management• Ventilation strategies• Physiological monitoring / CPR feedback• Etiology-specific therapies; alternative management strategies• Arrest pharmacology• Defibrillation• ECPR• Termination of Resuscitation 3) Post-Arrest Care• Physiological goals / neuroprotective strategies• Neuroprognostication• Survivorship4) Education and Systems of Care• Health-care provider education / Training programs / Simulation• In-hospital resuscitation systems, team composition, etc.Dr. Ryan Morgan received research funding (NIH and American Heart Association) to their institution for studies related to in-hospital cardiac arrest; active and previous collaborations and co-authorship with several of the proposed invited authors Topic editors: Catherine Ross, Ryan Morgan, Ari Moskowitz Source: https://www.frontiersin.org/research-topics/77570/advances-in-the-prevention-and-management-of-in-hospital-cardiac-arrest