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Autonomic Disorders: Advancing the Field Together with the first British Autonomic Society Meeting

Frontiers in Neurology and the British Autonomic Society (BAS) join forces on this special occasion to promote advances in Autonomic Disorders. In support of the goals of the first BAS Scientific Meeting (26-27 October 2026, The Francis Crick Institute, London; more information here), we are launching the current Research Topic to bring together clinicians and researchers in the field of Autonomic Disorders to discuss primary autonomic failure, reflex disorders, autoimmune autonomic conditions, and rare autonomic pathologies. Autonomic disorders encompass a broad spectrum of conditions affecting the regulation of blood pressure, heart rate, thermoregulation, and other involuntary functions. Despite growing recognition of their clinical burden, these disorders remain underdiagnosed and undertreated, in part due to heterogeneous presentations, limited biomarker validation, and gaps in diagnostic pathways. Autonomic medicine faces persistent challenges in translating mechanistic insight into reliable diagnostic tools and effective treatments: many patients experience delayed diagnosis, and clinicians often lack validated biomarkers to distinguish between overlapping autonomic syndromes or to predict disease trajectory. Recent advances in neurophysiological testing, imaging, and molecular biomarkers have begun to refine diagnostic accuracy and disease stratification, while emerging therapeutic strategies aim to address both symptomatic management and underlying disease mechanisms.This Research Topic aims to consolidate current knowledge and highlight new findings that advance the recognition, characterization, and management of autonomic disorders. Contributions should address diagnostic innovation, disease mechanisms, and treatment strategies across the autonomic disorder spectrum. By bringing together clinical and preclinical perspectives, this collection seeks to bridge gaps between bench research and bedside practice, supporting earlier diagnosis, better patient stratification, and improved therapeutic decision-making. The Research Topic welcomes contributions from clinicians and scientists engaging with the themes discussed at the British Autonomic Society meeting, extending the conversation to the wider international research community.We welcome submissions across a diverse range of manuscript types supported by the journal—including Original Research, Brief Research Reports, Perspectives, Protocols, Mini-Reviews, and more—exploring, but not limited to, the following themes:- Primary autonomic failure, including multiple system atrophy and pure autonomic failure- Orthostatic and reflex-mediated disorders, such as orthostatic hypotension and vasovagal syncope- Autoimmune and paraneoplastic autonomic neuropathies- Rare autonomic pathologies and their clinical recognition- Novel biomarkers and diagnostic techniques for autonomic dysfunction- The interface between autonomic disorders and broader brain health- Strategies for early detection and prevention of autonomic failure progressionAuthors are encouraged to submit work that advances diagnostic precision, clarifies disease mechanisms, or informs clinical management. Both clinical and preclinical studies are welcome, and clinically oriented submissions are particularly encouraged given the section’s translational focus.Articles will be published online as soon as they are accepted after peer review and approved for publication.This Research Topic has been organized in collaboration with the British Autonomic Society. Topic Editors Valeria Iodice and Giacomo Chiaro hold positions within the Society as President and Treasurer, respectively. Topic editors: Valeria Iodice, Giacomo Chiaro, Giorgia Melli Source: https://www.frontiersin.org/research-topics/86885/autonomic-disorders-advancing-the-field-together-with-the-first-british-autonomic-society-meeting

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