Beyond Borders: Integrated Antimicrobial Resistance Surveillance Across Human, Environmental, and Zoonotic Interfaces

The rapid dissemination of antimicrobial resistance (AMR) is a quintessential "One Health" challenge, as resistant pathogens and genetic determinants move fluidly between humans, animals, and the environment. While individual sectors have made strides in monitoring resistance, surveillance remains largely fragmented. The goal of this Research Topic is to bridge these silos by showcasing integrated surveillance strategies that track the flow of AMR across interfaces. We aim to highlight how longitudinal, cross-sectoral data can inform public health interventions, veterinary practices, and environmental regulations to mitigate the global AMR crisis. We invite original research, reviews, and perspective articles that address the technical, biological, and logistical challenges of multi-sectoral AMR surveillance. We are particularly interested in studies that do not merely report data from a single niche, but rather examine the interfaces where transmission occurs. Themes of interest include, but are not limited to:• Integrated Genomic Surveillance: Use of Whole Genome Sequencing (WGS) and metagenomics to track high-risk clones and mobile genetic elements (MGEs) across human clinics, livestock, and wastewater microbial populations.• Environmental Reservoirs: Role of soil, aquaculture, and urban water systems, along with associated antimicrobials and environmental contaminants, as reservoirs driving antimicrobial resistance evolution and influencing human and animal health.• Zoonotic Transmission Pathways: Quantitative assessments of AMR transmission dynamics through the food chain and direct animal-human contact, including horizontal gene transfer processes. • Technological Innovations: Development of harmonized data-sharing platforms, AI-driven predictive modeling for AMR outbreaks, and low-cost surveillance tools for resource-limited settings.• Policy and Socioeconomics: Evaluating the impact of "One Health" surveillance on antibiotic stewardship policies and the economic burden of AMR. Topic editors: Firdoos Ahmad Gogry, Sahana Vasudevan, Saravanan Matheshwaran, André O. Hudson Source: https://www.frontiersin.org/research-topics/85694/beyond-borders-integrated-antimicrobial-resistance-surveillance-across-human-environmental-and-zoonotic-interfaces