Carbon-Based or MOF-based Composite Nanomaterials for interfacial engineering, multifunctional integration, and structure–property–bioactivity relationships

Carbon-based and MOF-based nanomaterials have become outstanding biomedical materials due to large specific surface area, adjustable fluorescence, superior photothermal conversion efficiency and modifiable surface chemistry. In the past decade, graphene oxide, carbon quantum dots and carbon nanotubes have made great progress in bioimaging, tumor treatment and bone defect repair. However, prominent obstacles remain: high preparation cost, non-specific off-target toxicity, long-term in vivo biosafety risks and poor degradation performance of tissue scaffolds. This collection collects frontier findings to deepen the integration of carbon and MOF material science and translational biomedicine.Cutting-edge studies have proven carbon and MOF nanomaterials possess outstanding optical, electrical and structural advantages, yet multiple bottlenecks block their clinical transformation. This Research Topic aims to solve critical challenges: establishing clear structure-biocompatibility correlations, constructing high-performance carbon and MOF theranostic platforms, and optimizing carbon and MOF composite regenerative biomaterials. Researchers are expected to design multifunctional delivery systems for precise tumor diagnosis and synergistic treatment, fabricate biomimetic carbon and MOF scaffolds to boost tissue repair capacity, and unify standardized biosafety testing protocols. Integrated interdisciplinary outcomes will bridge laboratory research and preclinical translation of carbon and MOF biomedical nanomaterials.This topic related to biomedical engineering, covers carbon nanomaterials, MOFs and carbon/MOF hybrid composites for interdisciplinary biomedical research. Original articles, reviews, communications and technical methodology papers are all accepted. Core themes include green synthesis, surface engineering, multimodal bioimaging, combined tumor therapy, biomarker biosensors, carbon-MOF reinforced tissue scaffolds, and in vitro/in vivo biosafety assessment. Cross-disciplinary works integrating materials science, pharmacy and translational medicine are highly encouraged.• Green controllable synthesis and functional modification of carbon and MOF biomaterials • Carbon quantum dots/MOF hybrids for high-sensitivity bioimaging and early disease detection• Graphene/MOF nanoplatforms for chemo-photothermal synergistic tumor therapy • Carbon nanotube-MOF composite scaffolds for bone and neural tissue regeneration• Carbon/MOF hybrid biosensors for rapid, accurate biomarker detection • The fields related to biomedical engineering Topic editors: Jin Huang, Ronghe Gu Source: https://www.frontiersin.org/research-topics/84299/carbon-based-or-mof-based-composite-nanomaterials-for-interfacial-engineering-multifunctional-integration-and-structure-property-bioactivity-relationships