Clinical Research on Nutrition and Children's Health: Focusing on Genetics, Metabolism, and the Gut Microbiome - Volume II

With the continuous advancement of medical research, the crucial role of nutrition in the management of children's health and disease management has been increasingly paid attention to. Nutrition not only directly affects the progression and prognosis of diseases but also opens up new avenues for disease diagnosis, progression assessment, and treatment efficacy enhancement through interactions with genetics, metabolism, and gut microbiota.The Research Topic aims to select original articles and review articles in the fields of basic and clinical research, focusing mainly on evidence-based frameworks for precision nutrition interventions in pediatrics. From multiple perspectives including standardized health management and medical procedures, genetics, metabolic regulation, allergy and immunity, and gut microbiota, we analyze the mechanisms of the relationship between nutrition and pediatric diseases, as well as the important role of nutritional intervention in the diagnosis and treatment of pediatric diseases. The literature review should explain the research methods, present and analyze the research results, summarize and extract the core findings, and propose forward-looking suggestions. At the same time, these documents should strictly comply with the journal's writing style and format requirements.This Research Topic aims to gather further insights into the dynamic interplay between genetic predispositions, metabolic pathways, and gut microbiota composition in shaping nutritional outcomes and health trajectories among children. We welcome articles addressing, but not limited to, the following themes:- Identify genetic variants (e.g., SNPs in nutrient metabolism genes) that modulate individualized responses to dietary interventions by integrating multi-omics approaches.- Characterize metabolic signatures linked to micronutrient deficiencies, obesity, or food allergies in pediatric populations. - Decipher how gut microbiota-host interactions mediate nutrient absorption, immune function, and chronic disease risks (e.g., inflammatory bowel disease, obesity, and tumor).- Evaluate the potential of microbiota-directed therapies (e.g., probiotics, prebiotics) and genotype-tailored dietary strategies to optimize growth, neurodevelopment, and metabolic resilience in early life. Topic editors: Li Hong, Xiaonan Li Source: https://www.frontiersin.org/research-topics/81608/clinical-research-on-nutrition-and-childrens-health-focusing-on-genetics-metabolism-and-the-gut-microbiome---volume-ii