Disorders of motor circuit function: dystonia, ataxia, tremor, spasticity, and tic disorders

Motor circuit disorders represent a heterogeneous group of neurological conditions characterised by disruptions in the neural pathways governing voluntary and involuntary movement. Dystonia, ataxia, spasticity, and tic disorders — despite their distinct clinical presentations — share common threads in their underlying pathophysiology, involving dysfunction across cortico-basal ganglia-thalamo-cortical and cerebellar circuits. Advances in neuroimaging, electrophysiology, genetics, and neuromodulation have significantly expanded our understanding of these conditions, yet many questions remain regarding their mechanisms, progression, and optimal management.This Research Topic aims to bring together research on the pathophysiology, diagnosis, and treatment of motor circuit disorders, with a particular focus on dystonia, ataxia, spasticity, and tic disorders. We welcome contributions spanning basic neuroscience, translational research, and clinical studies. We invite submissions covering, but not limited to, the following themes: • Neural circuit mechanisms underlying dystonia, ataxia, spasticity, and tic disorders• Neuroimaging and electrophysiological biomarkers for diagnosis and disease monitoring• Neuromodulation approaches, including deep brain stimulation (DBS), transcranial magnetic stimulation (TMS), and transcranial direct current stimulation (tDCS)• Pharmacological and rehabilitative interventions and their effects on motor circuit function• Paediatric versus adult presentations and disease trajectories across the lifespan• Emerging technologies and digital tools for movement analysis and monitoring• Comorbidities, including cognitive and psychiatric features of motor circuit disorders Topic editors: Mariam Hull, Augusto Fusco Source: https://www.frontiersin.org/research-topics/80847/disorders-of-motor-circuit-function-dystonia-ataxia-tremor-spasticity-and-tic-disorders