Environmental Pollutants and Endocrine Regulation in Fish

Fish are continuously exposed to a wide range of environmental pollutants, including pesticides, pharmaceuticals, industrial chemicals, heavy metals, microplastics, and other emerging contaminants. Many of these substances can act as endocrine disruptors, interfering with the hormonal systems that regulate growth, reproduction, metabolism, development, behavior, and stress responses. Given their ecological importance, sensitivity to aquatic contamination, and value as vertebrate models, fish provide a unique opportunity to investigate how environmental stressors alter endocrine function and affect organismal health. Recent advances in molecular endocrinology, ecotoxicology, and omics technologies have expanded our understanding of the mechanisms through which pollutants disrupt endocrine pathways in fish and the consequences for aquatic populations and ecosystems.This Research Topic aims to advance our understanding of endocrine regulation in fish under conditions of environmental pollutant exposure. We seek contributions that explore how contaminants affect key endocrine axes, including reproductive, thyroid, growth, metabolic, and stress-related pathways, and how these disruptions influence physiology, development, fitness, and population resilience. Particular emphasis will be placed on studies that elucidate mechanisms of endocrine disruption in fish, identify biomarkers of exposure and effect, and improve our ability to assess environmental risks in aquatic ecosystems. By integrating laboratory, field-based, and translational research, this collection will provide new insights into the endocrine consequences of pollution in fish and their broader ecological implications.We welcome contributions addressing, but not limited to, the following themes:• Endocrine-disrupting contaminants and their effects on hormonal signaling pathways in fish• Pollutant-induced alterations of reproductive, thyroid, growth, metabolic, and stress endocrine axes• Molecular, cellular, and multi-omics mechanisms underlying endocrine disruption• Developmental, reproductive, behavioral, and transgenerational consequences of pollutant exposure• Emerging contaminants, contaminant mixtures, and real-world exposure scenarios in aquatic environments• Biomarkers, ecological impacts, and risk assessment of endocrine disruption in fish populations Topic editors: Joseph H Bisesi, Christopher J Martyniuk, Mingzhe Yuan Source: https://www.frontiersin.org/research-topics/84557/environmental-pollutants-and-endocrine-regulation-in-fish