Exploring Beneficial Effects of Bioactive Compounds from Food Wastes in Physiopathological Conditions

The escalating global challenge of food waste carries dire environmental and economic repercussions. However, this issue also presents a unique opportunity through the abundance of bioactive compounds found in food by-products such as peels, seeds, and pomace. These compounds, which include polyphenols, flavonoids, carotenoids, and dietary fibers, have demonstrated significant antioxidant, anti-inflammatory, antimicrobial, and anticancer properties. They have potential relevance in therapeutic applications and align well with circular economy principles by promoting waste reduction. Malfunctioning molecular pathways such as oxidative stress, mitochondrial dysfunction, and chronic inflammation play critical roles in numerous diseases, including metabolic disorders, cardiovascular diseases, neurodegenerative diseases, and cancers. Bioactives derived from food waste have shown promise in modulating these pathways and offering protective or therapeutic effects.This Research Topic aims to further delve into the therapeutic prospects of bioactive compounds sourced from food waste. While their health benefits are acknowledged, gaps remain in comprehensively understanding their molecular mechanisms of action, bioavailability, and practical clinical applications. Given the growing interest in linking food waste valorization to health advancements, it is crucial to explore these bioactives through molecular docking, metabolomics, and high-throughput screening techniques. Doing so will serve to bridge existing knowledge gaps and enhance their potential in disease management and therapy.To gather further insights within this interdisciplinary domain, we welcome contributions focusing on, but not limited to, the following themes:- Molecular characterization of bioactive compounds from food waste- Mechanistic insights into the modulatory effects of these compounds on cellular and molecular pathways- Green extraction techniques for isolating and purifying these compounds- Bioavailability and pharmacokinetics of food waste-derived bioactives- Innovative applications of these compounds in preventing or treating various physiopathological conditionsOriginal Research Articles, Reviews, and Mini-Reviews are welcome to be submitted to this Research Topic. Topic editors: Valeria Consoli, Giuseppe Antonio Malfa, Valeria Sorrenti, Ekaterina Kozuharova Source: https://www.frontiersin.org/research-topics/79039/exploring-beneficial-effects-of-bioactive-compounds-from-food-wastes-in-physiopathological-conditions