Exploring Biochemical Pathways in Dyslipidemia and Hyperglycemia-Induced Atherosclerosis

In the field of cardiovascular research, dyslipidemia and hyperglycemic conditions are widely recognized as significant risk factors for atherosclerotic cardiovascular diseases, such as coronary artery disease, peripheral artery disease, and stroke. These conditions do not merely act as independent risk factors but initiate a complex and interconnected series of biochemical cascades that accelerate the pathological process of atherosclerosis. Notably, lipid oxidation, inflammatory cytokine release, and endothelial dysfunction are critical contributors to the progression of atherosclerosis under dyslipidemic and diabetic environments. A comprehensive understanding of these biochemical and molecular-level changes is crucial to developing effective preventive measures and innovative therapeutic strategies.This Research Topic aims to elucidate the mechanisms that define the characteristic pathophysiological features occurring in the early stages of atherosclerosis. Recognizing these initial changes is vital as they play a crucial role in the development and progression of atherosclerotic cardiovascular disease. By closely examining early-stage pathology, the objective is to identify novel molecules and pathways that could potentially serve as future targets for intervention, thereby establishing more effective treatment approaches.To gather further insights in the latest findings on the molecular mechanisms of atherosclerosis, we welcome articles addressing, but not limited to, the following themes:o Cellular and Molecular Biologyo Gene Expression and Signalingo Metabolic Mechanismso Immunological AspectsWe invite a wide range of submissions, including research based on in vitro studies, animal models, or investigations involving human subjects. Topic editors: Michishige Terasaki Source: https://www.frontiersin.org/research-topics/80793/exploring-biochemical-pathways-in-dyslipidemia-and-hyperglycemia-induced-atherosclerosis