Food-Derived Bioactive Compounds in Gut Endocrine Signaling and Metabolic Regulation

The gastrointestinal endocrine system is an important regulator of metabolic responses to food intake, coordinating communication between the gut and peripheral organs involved in glucose and energy balance. Increasing attention is being given to food derived bioactive compounds that may influence these pathways and contribute to metabolic regulation.This Research Topic aims to explore how bioactive components of foods affect gut endocrine function and how these responses influence systemic metabolism in health and metabolic disease. Particular emphasis will be placed on mechanisms involving gastrointestinal hormones, intestinal signaling pathways, gut-organ communication, and interactions with microbial metabolites where these directly affect endocrine function.Topics of interest include:• Food - derived bioactive compounds and gut hormone regulation• GLP-1, GIP, and other gastrointestinal endocrine pathways• Gastrointestinal receptor signaling in response to dietary bioactives• Functional foods and plant-derived compounds affecting gut endocrine function• Gut-pancreas, gut-liver, gut-muscle, and gut-adipose communication• Gut endocrine mechanisms involved in glucose regulation and insulin sensitivity• Interactions between dietary bioactives, microbial metabolites, and endocrine signaling• Molecular and metabolomic approaches to diet–gut endocrine interactions• Preclinical and clinical investigation of gut endocrine responses to food-derived compounds Topic editors: Marisa Frederico, Marcela Aragon, Paulo Iury Gomes Nunes Source: https://www.frontiersin.org/research-topics/85556/food-derived-bioactive-compounds-in-gut-endocrine-signaling-and-metabolic-regulation