Golgi Biogenesis and Trafficking Dynamics: Mechanisms of Organelle Organisation and Membrane Flow

The Golgi apparatus is a central hub for protein and lipid processing, sorting, and distribution in eukaryotic cells. Its biogenesis and function depend on highly coordinated membrane formation, trafficking, and remodelling events that connect the Golgi with the endoplasmic reticulum, endosomes, and plasma membrane. Advances in live-cell and super-resolution imaging have revealed that, beyond vesicles, tubules and direct membrane continuities also contribute to Golgi connectivity and cargo flow. However, the molecular mechanisms that establish and maintain these dynamic structures remain only partly understood.This Research Topic aims to gather experimental studies and reviews that advance our understanding of Golgi biogenesis and trafficking dynamics across diverse eukaryotes-including animals, plants, and fungi. We welcome multidisciplinary contributions using imaging, molecular, biochemical, and structural approaches to dissect how the Golgi forms, remodels, and coordinates membrane traffic with other organelles. Studies linking Golgi organization to development, stress responses, or disease are particularly encouraged.Areas to be covered may include, but are not limited to:• Mechanisms of Golgi formation, maintenance, and turnover• Tubule formation, vesicle budding, tethering, and fusion around the Golgi apparatus• ER-Golgi and post-Golgi trafficking pathways across eukaryotic systems• Coordination of Golgi dynamics with the cytoskeleton and motor proteins• Organelle contact sites and membrane exchange mechanisms• Imaging and experimental analysis of Golgi architecture and membrane dynamics Topic editors: Akihiko Nakano Source: https://www.frontiersin.org/research-topics/81823/golgi-biogenesis-and-trafficking-dynamics-mechanisms-of-organelle-organisation-and-membrane-flow