New Vaccines and Drugs for Human Microbial Infections, Vol II

According to the World Health Organization (WHO), infectious diseases are the second global cause of death after cardiovascular diseases. Most are lower respiratory tract infections, and most pathogens are microorganisms, including viruses, bacteria, protists, and fungi. Profilaxis and treatment are essential for epidemiological control and mortality and morbidity decrease. In many cases, safer and more effective vaccines and drugs are urgent. A special issue of concern is antibiotic resistance. The WHO predicted that the number of deaths related to antimicrobial resistance will rise from 0.7 to 10 million by 2050.The main objective of this Research Topic is to report of new confirmed drug targets, drugs, and protective antigens of microbial pathogens, as well as their implementation in new treatments and vaccines undergoing preclinical or clinical studies or in significant improvements to the existing ones. The second objective is the description of new strategies for antigen, vaccine, drug target, or drug discovery.The term microbial pathogens include any zoonotic or anthroponotic infectious microorganism capable of causing human diseases. In this Research Topic, original articles and reviews are welcome, especially those focused on intracellular pathogens. The subtopics are:1. Strategies for antigen and drug target discovery2. Discovery and validation of vaccine-candidate antigens3. New drug targets4. Discovery of new antibiotics5. Design of new drugs6. Drug repurposing7. Preclinical testing of new vaccine and drug formulations in animalPlease the first edition of this Research Topic here: https://fro.ntiers.in/VykDI1kie4b Topic editors: Pedro José Alcolea, Thamir A. Alandijany, Ana Alonso Ayala Source: https://www.frontiersin.org/research-topics/83115/new-vaccines-and-drugs-for-human-microbial-infections-vol-ii