openEHR and the Open Platform Ecosystem: Clinical Models, Vendor-Neutral Architectures, and Collaboration Across Standards for Interoperable, Patient-Centred Care, Clinical Research

Health systems worldwide face persistent fragmentation of clinical data across proprietary systems, hindering care coordination, patient safety, and the secondary use of data for research, public health, and AI. Despite decades of standardisation efforts, most electronic health record deployments remain locked into vendor-specific data models that limit semantic interoperability and long-term data portability. The open platform approach, anchored in the openEHR specifications, offers an alternative architecture based on vendor-neutral, standardised clinical models managed collaboratively by clinicians and informaticians.The goal of this Research Topic is to consolidate and advance the evidence base around openEHR and the open platform paradigm, drawing on implementation experience, clinical modelling practice, and real-world health system deployments across diverse geographies and care settings. It aims to surface both mature findings and emerging research questions at the intersection of open specifications, interoperability, clinical research and collaborative health data governance.Suitable themes for manuscripts include (but are not limited to):• Design, governance, and lifecycle management of openEHR archetypes and templates in clinical practice. • National and regional open platform deployments: architecture, adoption, and lessons learned.• Interoperability between openEHR and other health data standards (HL7 FHIR, SNOMED CT, OMOP, ICD, LOINC). • Vendor-neutral, standards-based approaches to longitudinal health records and data portability. • Clinical decision support, care pathways, and guidelines modelling using openEHR specifications. • Secondary use of openEHR-based clinical data for population health, research, and AI/machine learning. • Open platform approaches within the European Health Data Space (EHDS) and cross-border health data exchange. • Clinician and end-user engagement in clinical modelling and open specification co-design.• Implementation science perspectives on open platform adoption: barriers, facilitators, and sustainability. • Collaborative governance models across standards development organisations for health data interoperability.• Synthetic health data generation from openEHR-based repositories: methods, validation, and applications for research, education, and AI training.• Prospective clinical research trials for e’source data capture of adverse events, patient reported outcomes, pharmacovigilance and submission to regulatory agencies. Topic editors: Jordi Piera-Jiménez, Michael Marschollek, John D Powderly II, MD, Shinji Kobayashi Source: https://www.frontiersin.org/research-topics/81458/openehr-and-the-open-platform-ecosystem-clinical-models-vendor-neutral-architectures-and-collaboration-across-standards-for-interoperable-patient-centred-care-clinical-research