Sustainable Biomaterials from Bioresources for Bone and Hard Tissue Regeneration

Natural biomaterials derived from renewable bioresources and biological waste have emerged as sustainable alternatives to conventional synthetic biomaterials for biomedical applications. Marine by-products, agricultural residues, and other biological resources represent abundant sources of naturally occurring polymers and bioceramics, including chitin, chitosan, collagen, silk fibroin, alginate, aragonite, coral-derived minerals, and calcium phosphates. Recent advances in environmentally friendly extraction and processing have enabled the production of high-quality biomaterials with the biocompatibility, bioactivity, and physicochemical properties needed for tissue regeneration. Beyond reducing the environmental burden of waste disposal, these approaches support circular bioeconomy principles by transforming underutilised bioresources into high-value biomedical materials.This Research Topic focuses on how sustainably sourced natural biomaterials can be designed and validated for bone and hard tissue regeneration, where the demand for environmentally responsible alternatives to conventional grafts and synthetic ceramics is growing fastest. Rather than treating green processing and biological performance as separate stories, the collection asks contributors to connect them: to show how the origin and environmentally friendly processing of a biomaterial shape its structure and properties, and how those properties translate into biological function in hard tissue repair.We particularly welcome studies that establish clear links across the full chain: bioresource origin and green extraction, physicochemical and structural characterisation, and biological performance in bone and hard tissue regeneration. Topics of interest include, but are not limited to:o Green extraction, purification, and processing of natural polymers and bioceramics from marine, agricultural, and other biological waste streamso Structure–property–function relationships governing biological and regenerative performanceo Scaffold and composite design for bone and hard tissue engineeringo Biomaterial–cell interactions, bioactivity, mineralisation, and osteogenic responseo Biodegradation behaviour and its effect on tissue healingo Translational advances moving renewable biomaterials from laboratory research toward biomedical applicationTo maintain a cohesive scientific focus, submissions must include both physicochemical/structural characterisation and biological or biomedical evaluation relevant to tissue regeneration. Studies limited to extraction, processing, or environmental performance without biological or biomedical validation, and work whose primary emphasis is environmental science rather than biomaterials, fall outside the scope of this collection. Topic editors: Youssef Ait Hamdan, Syed Baker, Samia Elouali, ANASS BELBACHIR Source: https://www.frontiersin.org/research-topics/84233/sustainable-biomaterials-from-bioresources-for-bone-and-hard-tissue-regeneration