Synthetic Biology in Pharmacology: Engineering Circuits and Cells for Therapeutics

Synthetic biology, an interdisciplinary field blending principles from molecular biology, organic chemistry, computational modeling, and nanobiotechnology, focuses on creating new biological systems and re-engineering existing ones. Recent advancements in developing complex genetic circuits and nano-scale structures have significantly expanded its applications in biomedicine.This Research Topic aims to explore the specific roles of synthetic gene circuits, metabolic engineering, and artificial cells in revolutionizing drug development. By harnessing these cutting-edge techniques, researchers can design novel systems tailored for therapeutic use, paving the way for transformative advancements in disease treatment and health care.We invite articles focusing on the following themes:• Design and Optimization of Synthetic Gene Circuits: Creating gene networks to modulate drug responses or for therapeutic applications.• Metabolic Engineering for Drug Production: Developing efficient microbial or cellular systems for synthesizing pharmaceuticals, including antibiotics and anticancer agents.• Development of Artificial Cells for Drug Delivery: Constructing synthetic systems to study drug interactions and enhance delivery mechanisms.Submissions that delve into these topics will highlight the critical role of synthetic biology in shaping the future of pharmacology. Topic editors: Michelle Jansman, Xingli Cun, Xiaowei Li Source: https://www.frontiersin.org/research-topics/69285/synthetic-biology-in-pharmacology-engineering-circuits-and-cells-for-therapeutics