The Future of Neurosurgical Oncology: AI, Translational Science, and Surgical Innovation

This Research Topic explores the future of neurosurgical oncology, driven by artificial intelligence, translational science, and cutting-edge surgical innovation. From cranial to spinal procedures, and from the operating room to real-world data systems, this collection aims to spotlight the tools and techniques transforming how neurosurgeons plan, operate, and deliver care across all settings.By bridging neurosurgery, cancer neuroscience, and translational oncology through artificial intelligence and clinical informatics, this collection underscores the multidisciplinary evolution of modern neurosurgical oncology.We welcome submissions that advance our understanding of next-generation neurosurgical practice, including original research, technical innovations, translational frameworks, and operative case insights. This Topic is timely, interdisciplinary, and globally relevant, reflecting the accelerating transformation in surgical intelligence and the evolving role of neurosurgeons in brain and spine oncology.Thematic Areas:- Intelligent Technologies and Data-Driven Neurosurgery- AI and machine learning for surgical planning, outcome prediction, and workflow optimization- Clinical informatics and predictive analytics in real-time neurosurgical care- Decision support tools, digital registries, and real-world datasets- Translational Science and Surgical Innovation- Integration of radiomics, genomics, and intraoperative data streams- Novel platforms for tissue characterization and precision surgery- Innovation at the interface of engineering, imaging, and neurosurgical research- Evolving Surgical Techniques and Protocols- Robotics, endoscopic approaches, intraoperative imaging, and AR/VR- Protocol development including, Enhanced Recovery After Surgery (ERAS, safety checklists, and minimally invasive pathways- Global comparisons of technique adaptation and innovation scaling- Special Focus: Brain Tumor Surgery and Neuro-Oncology- AI-powered tumor segmentation, intraoperative guidance, and supramaximal resection- Neurosurgical roles in immunotherapy delivery, tissue banking, and targeted therapy trialsSuggested Article Types:- Original Research- Operative Techniques- Translational Mini-Reviews- Clinical Protocols- Perspectives or OpinionsThis Research Topic is timely and forward-thinking, aligning with the accelerating transformation in surgical intelligence. Its interdisciplinary scope will appeal to neurosurgeons, data scientists, translational researchers, and innovators. With high-impact potential, it reinforces the role of neurosurgical oncology in shaping the future of brain and spine care, and its global relevance ensures contributions from both high-resource and resource-constrained environments.Please note: Manuscripts consisting solely of bioinformatics, computational analysis, or predictions of public databases, which are not accompanied by validation (independent clinical or patient cohort, or biological validation in vitro or in vivo, which are not based on public databases), are not suitable for publication in this journal. Topic editors: Andres M Alvarez Pinzon, Edgar G. Ordóñez-Rubiano, MD, Jose Valerio Source: https://www.frontiersin.org/research-topics/75478/the-future-of-neurosurgical-oncology-ai-translational-science-and-surgical-innovation