The Role of Cell Metabolism in Development, Drug Resistance, and Survival Assessment in Cancer, volume II

This Research Topic is Volume II of a series. The previous volume can be found here:The Role of Cell Metabolism in Development, Drug Resistance, and Survival Assessment in Cancer.Cell metabolism is essential for cells to maintain their vital functions. Impaired cellular metabolism leads to defects in several important molecules, contributing to diseases such as Wilson's Disease, which is caused by dysfunction of cellular copper metabolism. Cellular metabolism has also now been shown to play an important role in the development of malignant tumors, e.g., lipid metabolism and amino acid metabolism, which can influence the survival of tumor cells by affecting the mitochondrial function of cells. Cellular metabolism includes ferroptosis due to abnormal phospholipid metabolism, cuproptosis due to abnormal copper metabolism, and more. The pooling of this content can help discover new therapeutic targets for tumor suppression from a cellular metabolism perspective or a combination of drug approaches to reverse tumor resistance. Despite the continuous progress in knowledge on tumor cell metabolism, still detailed aspects of tumor cell proliferation, metastasis, and drug resistance need to be further explored.This Research Topic aims to bring together novel content on cell metabolism about tumorigenesis, progression, drug resistance, and prognostic assessment, as well as on the identification of biomarkers using metabolomics approaches. We welcome content on cellular metabolism studies using cellular and animal experiments, as well as databases- and clinical cohorts-based analyses. We aim to publish articles on cell metabolism studies in cancer. Review and original research are welcome, including but not limited to the following contents:• Clinical metabolomics in the context of cancers• The effect of cell metabolism on the drug resistance of cancers• The relationship between gene mutation and cell metabolism• The prognostic assessment of patients with cancers by the metabolism-related biomarker Topic editors: Leilei Wu, Guowei Ma, Chang Gu, Fang Hu, Jian Zeng, Pritam Sadhukhan Source: https://www.frontiersin.org/research-topics/76612/the-role-of-cell-metabolism-in-development-drug-resistance-and-survival-assessment-in-cancer-volume-ii